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ARTICLES

Zeaxanthin, a Retinal Carotenoid, Protects Retinal Cells against Oxidative Stress

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Pages 311-318 | Received 08 Apr 2008, Accepted 11 Jan 2009, Published online: 02 Jul 2009

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Articles from other publishers (34)

Claudia Honisch, Umberto Rodella, Claudio Gatto, Paolo Ruzza & Jana D’Amato Tóthová. (2023) Oxidative Stress and Antioxidant-Based Interventional Medicine in Ophthalmology. Pharmaceuticals 16:8, pages 1146.
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Rajasekar Janani, Rani Elavarasan Anitha, Peethambaran Divya, Muzaffar Chonche & Vallikannan Baskaran. (2022) Astaxanthin ameliorates hyperglycemia induced inflammation via PI3K/Akt–NF–κB signaling in ARPE-19 cells and diabetic rat retina. European Journal of Pharmacology 926, pages 174979.
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Drake W. Lem, Dennis L. Gierhart & Pinakin Gunvant Davey. (2021) Carotenoids in the Management of Glaucoma: A Systematic Review of the Evidence. Nutrients 13:6, pages 1949.
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Po-Ting YehYun-Ju ChenNien-Chen LinAn-I YehChang-Hao Yang. (2020) The Ocular Protective Effects of Nano/Submicron Particles Prepared from Lycium barbarum Fruits Against Oxidative Stress in an Animal Model . Journal of Ocular Pharmacology and Therapeutics 36:3, pages 179-189.
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Thomas Lawler, Yao Liu, Krista Christensen, Thasarat S. Vajaranant & Julie Mares. (2019) Dietary Antioxidants, Macular Pigment, and Glaucomatous Neurodegeneration: A Review of the Evidence. Nutrients 11:5, pages 1002.
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Gehan El-Akabawy & Neveen M. El-Sherif. (2019) Zeaxanthin exerts protective effects on acetic acid-induced colitis in rats via modulation of pro-inflammatory cytokines and oxidative stress. Biomedicine & Pharmacotherapy 111, pages 841-851.
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Changjiang Ying, Lei Chen, Shanshan Wang, Yizhen Mao, Hongwei Ling, Wei Li & Xiaoyan Zhou. (2017) Zeaxanthin ameliorates high glucose-induced mesangial cell apoptosis through inhibiting oxidative stress via activating AKT signalling-pathway. Biomedicine & Pharmacotherapy 90, pages 796-805.
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Tomomi Masuda, Masamitsu Shimazawa & Hideaki Hara. (2017) Retinal Diseases Associated with Oxidative Stress and the Effects of a Free Radical Scavenger (Edaravone). Oxidative Medicine and Cellular Longevity 2017, pages 1-14.
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Ramar Manikandan, Raman Thiagarajan, Ganesh Goutham, Munusamy Arumugam, Manikandan Beulaja, Luca Rastrelli, Krystyna Skalicka-Woźniak, Solomon Habtemariam, Ilkay Erdogan Orhan, Seyed Fazel Nabavi & Seyed Mohammad Nabavi. (2016) Zeaxanthin and ocular health, from bench to bedside. Fitoterapia 109, pages 58-66.
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We Fong Siah, James Loughman & Colm O'Brien. (2015) Lower Macular Pigment Optical Density in Foveal-Involved Glaucoma. Ophthalmology 122:10, pages 2029-2037.
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Cassie L. Rayner, Glen A. Gole, Steven E. Bottle & Nigel L. Barnett. (2014) Dynamic, in vivo, real-time detection of retinal oxidative status in a model of elevated intraocular pressure using a novel, reversibly responsive, profluorescent nitroxide probe. Experimental Eye Research 129, pages 48-56.
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X Zou, J Gao, Y Zheng, X Wang, C Chen, K Cao, J Xu, Y Li, W Lu, J Liu & Z Feng. (2014) Zeaxanthin induces Nrf2-mediated phase II enzymes in protection of cell death. Cell Death & Disease 5:5, pages e1218-e1218.
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Sang Hoon Jung. 2014. Handbook of Nutrition, Diet and the Eye. Handbook of Nutrition, Diet and the Eye 423 439 .
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Samir Khandhadia, Angela Cree & Andrew Lotery. 2014. Systems Biology of Free Radicals and Antioxidants. Systems Biology of Free Radicals and Antioxidants 3625 3653 .
Yoshiki Koriyama, Yuya Nakayama, Seiichi Matsugo & Satoru Kato. (2013) Protective effect of lipoic acid against oxidative stress is mediated by Keap1/Nrf2-dependent heme oxygenase-1 induction in the RGC-5 cellline. Brain Research 1499, pages 145-157.
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Xinrong Xu, Li Hang, Binglin Huang, Yuanhua Wei, Shizhong Zheng & Wei Li. (2013) Efficacy of Ethanol Extract of Fructus lycii and Its Constituents Lutein/Zeaxanthin in Protecting Retinal Pigment Epithelium Cells against Oxidative Stress: In Vivo and In Vitro Models of Age-Related Macular Degeneration . Journal of Ophthalmology 2013, pages 1-10.
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Junji Tanaka, Tomohiro Nakanishi, Hiroshi Shimoda, Seikou Nakamura, Kazuhiro Tsuruma, Masamitsu Shimazawa, Hisashi Matsuda, Masayuki Yoshikawa & Hideaki Hara. (2013) Purple rice extract and its constituents suppress endoplasmic reticulum stress-induced retinal damage in vitro and in vivo. Life Sciences 92:1, pages 17-25.
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Zhihong Ren, Lixin Na, Yanmei Xu, Mitra Rozati, Junpeng Wang, Jianguo Xu, Changhao Sun, Karine Vidal, Dayong Wu & Simin Nikbin Meydani. (2012) Dietary Supplementation with Lacto-Wolfberry Enhances the Immune Response and Reduces Pathogenesis to Influenza Infection in Mice,. The Journal of Nutrition 142:8, pages 1596-1602.
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Antonio Gonzalez, Patricia Santofimia-Castaño, Ramon Rivera-Barreno & Gines M. Salido. (2011) Cinnamtannin B-1, a natural antioxidant that reduces the effects of H2O2 on CCK-8-evoked responses in mouse pancreatic acinar cells. Journal of Physiology and Biochemistry 68:2, pages 181-191.
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Juliana Mara Serpeloni, Gustavo Rafael Mazzaron Barcelos, José Pedro Friedmann Angeli, Adriana Zerlotti Mercadante, Maria Lourdes Pires Bianchi & Lusânia Maria Greggi Antunes. (2012) Dietary carotenoid lutein protects against DNA damage and alterations of the redox status induced by cisplatin in human derived HepG2 cells. Toxicology in Vitro 26:2, pages 288-294.
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Milam A. BrantleyJr.Jr., Melissa P. Osborn, Jiyang Cai & Paul SternbergJr.Jr.. 2012. Studies on Retinal and Choroidal Disorders. Studies on Retinal and Choroidal Disorders 367 397 .
Kyung-A Kim, Kui Dong Kang, Eun Ha Lee, Chu Won Nho & Sang Hoon Jung. (2011) Edible wild vegetable, Gymnaster koraiensis protects retinal ganglion cells against oxidative stress. Food and Chemical Toxicology 49:9, pages 2131-2143.
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Suk-Yee Li, Di Yang, Chung-Man Yeung, Wing-Yan Yu, Raymond Chuen-Chung Chang, Kwok-Fai So, David Wong & Amy C. Y. Lo. (2011) Lycium Barbarum Polysaccharides Reduce Neuronal Damage, Blood-Retinal Barrier Disruption and Oxidative Stress in Retinal Ischemia/Reperfusion Injury. PLoS ONE 6:1, pages e16380.
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Abeir Baltmr, James Duggan, Shereen Nizari, Thomas E. Salt & M. Francesca Cordeiro. (2010) Neuroprotection in glaucoma – Is there a future role?. Experimental Eye Research 91:5, pages 554-566.
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Sam Khandhadia & Andrew Lotery. (2010) Oxidation and age-related macular degeneration: insights from molecular biology. Expert Reviews in Molecular Medicine 12.
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Nan-Lin Wu, Yuh-Chiau Chiang, Chieh-Chen Huang, Jia-You Fang, Der-Fang Chen & Chi-Feng Hung. (2009) Zeaxanthin inhibits PDGF-BB-induced migration in human dermal fibroblasts. Experimental Dermatology 19:8, pages e173-e181.
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Hee Ju Lee, Kyung-A Kim, Kui Dong Kang, Eun Ha Lee, Chul Young Kim, Byung Hun Um & Sang Hoon Jung. (2010) The compound isolated from the leaves of Phyllostachys nigra protects oxidative stress-induced retinal ganglion cells death. Food and Chemical Toxicology 48:6, pages 1721-1727.
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Suk-Yee Li & Amy C. Y. Lo. (2010) Lutein Protects RGC-5 Cells Against Hypoxia and Oxidative Stress. International Journal of Molecular Sciences 11:5, pages 2109-2117.
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Sala Horowitz. (2010) A Holistic Look at Vision Health. Alternative and Complementary Therapies 16:1, pages 26-33.
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