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Current Eye Research Volume 42, 2017 - Issue 5
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Vitreous Body and Retina

The Relationship of Brimonidine Concentration in Vitreous Body to the Free Concentration in Retina/Choroid Following Topical Administration in Pigmented Rabbits

Keisuke ShinnoSenju Pharmaceutical Co., Ltd., Osaka, JapanCorrespondence[email protected]
,
Kazuya KurokawaSenju Pharmaceutical Co., Ltd., Osaka, Japan
,
Seiko KozaiSenju Pharmaceutical Co., Ltd., Osaka, Japan
,
Akio KawamuraSenju Pharmaceutical Co., Ltd., Osaka, Japan
,
Katsuhiro InadaSenju Pharmaceutical Co., Ltd., Osaka, Japan
&
Hideki TokushigeSenju Pharmaceutical Co., Ltd., Osaka, Japan
Pages 748-753 | Received 31 Mar 2016, Accepted 13 Sep 2016, Published online: 17 Nov 2016

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Koji Nitta, Shiro Shimamoto, Ryotaro Wajima, Gaku Tachibana, Yutaro Yamada, Miyuki Domoto, Ryuji Takeda, Yoshinari Takahashi & Kazuhisa Sugiyama. (2020) The Effect of Brimonidine 0.1% on Disc Hemorrhage in Primary Open-Angle Glaucoma Patients. Clinical Ophthalmology 14, pages 213-219.
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Articles from other publishers (9)

Aiqun XiangHong HeHanyang YuAnzhen LiYanting LuoJunming YangXingwu Zhong. (2023) Ocular Posterior Segment Distribution and Pharmacokinetics of Brimonidine After Intravitreal Administration in Guinea Pigs. Journal of Ocular Pharmacology and Therapeutics 39:7, pages 456-462.
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Sina Bahrpeyma, Mika Reinisalo, Laura Hellinen, Seppo Auriola, Eva M. del Amo & Arto Urtti. (2022) Mechanisms of cellular retention of melanin bound drugs: Experiments and computational modeling. Journal of Controlled Release 348, pages 760-770.
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Weiye Li. 2022. Age-Related Macular Degeneration. Age-Related Macular Degeneration 233 260 .
Mitalee Tamhane, Kenneth T. Luu & Mayssa Attar. (2021) Ocular Pharmacokinetics of Brimonidine Drug Delivery System in Monkeys and Translational Modeling for Selection of Dose and Frequency in Clinical Trials. Journal of Pharmacology and Experimental Therapeutics 378:3, pages 207-214.
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Gen Suzuki, Eriko Kunikane, Keisuke Shinno, Seiko Kozai, Masaaki Kurata & Akio Kawamura. (2020) Ocular and Systemic Pharmacokinetics of Brimonidine and Timolol After Topical Administration in Rabbits: Comparison Between Fixed-Combination and Single Drugs. Ophthalmology and Therapy 9:1, pages 115-125.
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Paulina Jakubiak, Carina Cantrill, Arto Urtti & Rubén Alvarez-Sánchez. (2019) Establishment of an In Vitro–In Vivo Correlation for Melanin Binding and the Extension of the Ocular Half-Life of Small-Molecule Drugs. Molecular Pharmaceutics 16:12, pages 4890-4901.
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Keisuke Shinno, Kazuya Kurokawa, Seiko Kozai, Akio Kawamura, Katsuhiro Inada & Hideki Tokushige. (2019) Effect of Solution pH on Distribution of Ophthalmically Administered Brimonidine in Posterior Ocular Tissues in Pigmented Rabbits. Ophthalmology and Therapy 8:2, pages 271-277.
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Paulina Jakubiak, Michael Reutlinger, Patrizio Mattei, Franz Schuler, Arto Urtti & Rubén Alvarez-Sánchez. (2018) Understanding Molecular Drivers of Melanin Binding To Support Rational Design of Small Molecule Ophthalmic Drugs. Journal of Medicinal Chemistry 61:22, pages 10106-10115.
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Anna-Kaisa Rimpelä, Mika Reinisalo, Laura Hellinen, Evgeni Grazhdankin, Heidi Kidron, Arto Urtti & Eva M. del Amo. (2018) Implications of melanin binding in ocular drug delivery. Advanced Drug Delivery Reviews 126, pages 23-43.
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