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Current Eye Research Volume 44, 2019 - Issue 3
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Extraocular Conditions

Therapeutic Effect of Intense Pulsed Light on Ocular Demodicosis

XiaoZhao ZhangDepartment of Ophthalmology and Vision Science, The Eye & ENT Hospital of Fudan University, Shanghai, China;NHC Key Laboratory of Myopia (Fudan University); Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, ChinaView further author information
,
Nan SongNHC Key Laboratory of Myopia (Fudan University); Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China;Department of Laser Plastic Surgery, The Eye & ENT Hospital of Fudan University, Shanghai, ChinaCorrespondence[email protected]
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&
Lan GongDepartment of Ophthalmology and Vision Science, The Eye & ENT Hospital of Fudan University, Shanghai, China;NHC Key Laboratory of Myopia (Fudan University); Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, ChinaCorrespondence[email protected]
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Pages 250-256 | Received 30 Jun 2018, Accepted 08 Oct 2018, Published online: 25 Oct 2018

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Weiliang Zhang, Xiaoqin Cao, Lu Yang, Yajian Duan & Wei Zhang. (2023) Analysis of Treatment Efficacy of Intense Pulsed Light (M22) for Meibomian Gland Dysfunction with Demodex Mites. Clinical, Cosmetic and Investigational Dermatology 16, pages 3743-3751.
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Jameson Loyal, Emily Carr, Rawaa Almukhtar & Mitchel P Goldman. (2021) Updates and Best Practices in the Management of Facial Erythema. Clinical, Cosmetic and Investigational Dermatology 14, pages 601-614.
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Nihal Altunisik, Dursun Turkmen & Serpil Sener. (2021) Evaluation of the effect of 577-nm pro-yellow laser on demodex intensity. Journal of Cosmetic and Laser Therapy 23:7-8, pages 221-224.
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Carlos Vergés, José Salgado-Borges, Francesc March de Ribot & Verónica Ribas. (2021) Current developments of intensive pulsed light treatment for dry eye disease and meibomian gland dysfunction. Expert Review of Ophthalmology 16:5, pages 401-409.
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Etty Bitton & Sarah Aumond. (2021) Demodex and eye disease. Clinical and Experimental Optometry 104:3, pages 285-294.
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Fredrik Fineide, Morten S. Magnø, Ayyad Zartasht Khan, Xiangjun Chen, Jelle Vehof & Tor P. Utheim. (2023) Intense pulsed light treatment in meibomian gland dysfunction: Past, present, and future. Acta Ophthalmologica 102:4.
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Nikhil Sharma, Eilidh Martin, Edward Ian Pearce & Suzanne Hagan. (2024) A Delphi approach to establishing consensus on best practice for the diagnosis and treatment of Demodex blepharitis. Contact Lens and Anterior Eye 47:1, pages 102080.
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Omur O. Ucakhan, Tuna Celik-Buyuktepe, Lin Yang, Brian Wogu & Penny A. Asbell. (2023) Update on Dry Eye Disease Treatment: Evidence From Randomized Controlled Trials. Eye & Contact Lens: Science & Clinical Practice 49:12, pages 542-568.
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Xi Song, Chunying Zhang, Saisai Zhang & Mansha He. (2023) Therapeutic efficacy of optimal pulse technology in the treatment of chalazions. Frontiers in Medicine 10.
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He Wang, Xiaoyue Yin, Yue Li, Zhaowei Zhang, Kai Zhao, Fen Hu, Qian Liu, Qiuchen Lu, Yining Wang, Ling Zhang, Hui Jia, Jiaxin Han, Jianxin Guo & Mingxin Li. (2023) Safety and efficacy of intense pulsed light in the treatment of severe chronic ocular graft-versus-host disease. The Ocular Surface 30, pages 276-285.
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Ilan Feldman, Judit Krausz, Oz Levinkron, Joel Gutovitz, Natalia Edison, Eyal Cohen, Mark Krauthammer & Daniel Briscoe. (2023) Is Demodex Blepharitis Connected With Cataract Surgery?. American Journal of Ophthalmology 254, pages 31-35.
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Michelle K. Rhee, Elizabeth Yeu, Melissa Barnett, Christopher J. Rapuano, Deepinder K. Dhaliwal, Kelly K. Nichols, Paul Karpecki, Francis S. Mah, Arthur Chan, James Mun & Ian Benjamin Gaddie. (2023) Demodex Blepharitis: A Comprehensive Review of the Disease, Current Management, and Emerging Therapies. Eye & Contact Lens: Science & Clinical Practice 49:8, pages 311-318.
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Hongya ZengLan Gong. (2023) A Review of Applications and Intracellular Mechanisms of Intense Pulsed Light in Eyelid Inflammatory Diseases. Photobiomodulation, Photomedicine, and Laser Surgery 41:3, pages 104-119.
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Malachie Ndikumukiza, Yu-Ting Xiao, You-Fan Ye, Jia-Song Wang, Xi Peng, Hua-Tao Xie & Ming-Chang Zhang. (2023) Botulinum Neurotoxin Type a Injection Combined with Absorbable Punctal Plug Insertion: An Effective Therapy for Blepharospasm Patients with Dry Eye. Journal of Clinical Medicine 12:3, pages 877.
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Jiahua Li, Erdong Wei, Amin Reisinger, Lars Einar French, Benjamin M. Clanner-Engelshofen & Markus Reinholz. (2023) Comparison of Different Anti-Demodex Strategies: A Systematic Review and Meta-Analysis. Dermatology 239:1, pages 12-31.
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Yahui Lei, Jing Peng, Jiayan Liu & Jingxiang Zhong. (2022) Intense pulsed light (IPL) therapy for meibomian gland dysfunction (MGD)–related dry eye disease (DED): a systematic review and meta-analysis. Lasers in Medical Science 38:1.
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Jeremy J. Kudrna, Clever Nguyen & Gargi K. Vora. (2022) Intense Pulse Light Therapy for Meibomian Gland Dysfunction. Current Ophthalmology Reports 10:4, pages 138-152.
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A. Caravaca, J.L. Alió del Barrio, M.C. Martínez Hergueta & M.A. Amesty. (2022) Intense pulsed light combined with meibomian gland expression for chalazion management. Archivos de la Sociedad Española de Oftalmología (English Edition) 97:9, pages 490-496.
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A. Caravaca, J.L. Alió del Barrio, M.C. Martínez Hergueta & M.A. Amesty. (2022) Luz pulsada intensa combinada con expresión de las glándulas de Meibomio para el tratamiento del chalación. Archivos de la Sociedad Española de Oftalmología 97:9, pages 490-496.
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Jeongseop Yun & Ji Sang Min. (2022) Skin temperature change in patients with meibomian gland dysfunction following intense pulsed light treatment. Frontiers in Medicine 9.
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Solomon Abrha Bezabh, Wubshet Tesfaye, Julia K. Christenson, Christine F. Carson & Jackson Thomas. (2022) Antiparasitic Activity of Tea Tree Oil (TTO) and Its Components against Medically Important Ectoparasites: A Systematic Review. Pharmaceutics 14:8, pages 1587.
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Rolando Toyos, Neel R. Desai, Melissa Toyos & Steven J. Dell. (2022) Intense pulsed light improves signs and symptoms of dry eye disease due to meibomian gland dysfunction: A randomized controlled study. PLOS ONE 17:6, pages e0270268.
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Yanan Huo, Qi Wan, Xinzhu Hou, Zhiyong Zhang, Jinchuan Zhao, Zhiyi Wu & Xiuming Jin. (2022) Therapeutic Effect of Intense Pulsed Light in Patients with Sjögren’s Syndrome Related Dry Eye. Journal of Clinical Medicine 11:5, pages 1377.
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Zhiyuan Li, Haiyan Wang, Mo Liang, Zhenghua Li, Yvliang Li, Xiaoping Zhou & Guoping Kuang. (2022) Hypochlorous Acid Can Be the Novel Option for the Meibomian Gland Dysfunction Dry Eye through Ultrasonic Atomization. Disease Markers 2022, pages 1-12.
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Dayron F. Martínez-Pulgarín, Marcel Y. Ávila & Alfonso J. Rodríguez-Morales. (2021) Interventions for Demodex blepharitis and their effectiveness: A systematic review and meta-analysis. Contact Lens and Anterior Eye 44:6, pages 101453.
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Roberto Gonzalez-Salinas, Elizabeth Yeu, Mark Holdbrook, Stephanie N. Baba, Juan Carlos Ceballos, Martha Massaro-Corredor, Claudia Corredor-Ortega, Nallely Ramos-Betancourt & Hugo Quiroz-Mercado. (2021) Safety and Efficacy of Topical Lotilaner Ophthalmic Solution 0.25% for the Treatment of Demodex Blepharitis: A Pilot Study. Journal of Ophthalmology 2021, pages 1-7.
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慧 高. (2021) Research Progress on the Pathogenic Mechanism of Demodex-Related Ocular Diseases. Hans Journal of Ophthalmology 10:02, pages 69-75.
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Xiaoming Yan, Jing Hong, Xiuming Jin, Wei Chen, Bei Rong, Yun Feng, Xiaodan Huang, Jinyang Li, Wenjing Song, Lin Lin & Yu Cheng. (2021) The Efficacy of Intense Pulsed Light Combined With Meibomian Gland Expression for the Treatment of Dry Eye Disease Due to Meibomian Gland Dysfunction: A Multicenter, Randomized Controlled Trial. Eye & Contact Lens: Science & Clinical Practice 47:1, pages 45-53.
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Di ChenJingyi WangDavid A. SullivanWendy R. KamYang Liu. (2020) Effects of Terpinen-4-ol on Meibomian Gland Epithelial Cells In Vitro. Cornea 39:12, pages 1541-1546.
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W. Ben Hadj Salah, C. Baudouin, S. Doan, A. Angoulvant, J. Gottlieb, J. Bénichou, E. Da Cunha, L. Eid, M. Labetoulle & A. Rousseau. (2020) Demodex et pathologies de la surface oculaire. Journal Français d'Ophtalmologie 43:10, pages 1069-1077.
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Behzod Tashbayev, Mazyar Yazdani, Reiko Arita, Fredrik Fineide & Tor Paaske Utheim. (2020) Intense pulsed light treatment in meibomian gland dysfunction: A concise review. The Ocular Surface 18:4, pages 583-594.
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Edward J. Wladis, Vinay K. Aakalu, Jill A. Foster, Suzanne K. Freitag, Rachel K. Sobel, Jeremiah P. Tao & Michael T. Yen. (2020) Intense Pulsed Light for Meibomian Gland Disease. Ophthalmology 127:9, pages 1227-1233.
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Harvey A. FishmanLaura M. PerimanAmi A. Shah. (2020) Real-Time Video Microscopy of In Vitro Demodex Death by Intense Pulsed Light . Photobiomodulation, Photomedicine, and Laser Surgery 38:8, pages 472-476.
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Alexis Ceecee Zhang, Alex Muntz, Michael T M Wang, Jennifer P Craig & Laura E Downie. (2020) Ocular Demodex : a systematic review of the clinical literature . Ophthalmic and Physiological Optics 40:4, pages 389-432.
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Keyur Savla, Jimmy T Le & Andrew D Pucker. (2020) Tea tree oil for Demodex blepharitis. Cochrane Database of Systematic Reviews 2022:1.
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Diane Thiboutot, Rox Anderson, Fran Cook-Bolden, Zoe Draelos, Richard L. Gallo, Richard D. Granstein, Sewon Kang, Marian Macsai, Linda Stein Gold & Jerry Tan. (2020) Standard management options for rosacea: The 2019 update by the National Rosacea Society Expert Committee. Journal of the American Academy of Dermatology 82:6, pages 1501-1510.
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Ally L. Xue, Michael T.M. Wang, Susan E. Ormonde & Jennifer P. Craig. (2020) Randomised double-masked placebo-controlled trial of the cumulative treatment efficacy profile of intense pulsed light therapy for meibomian gland dysfunction. The Ocular Surface 18:2, pages 286-297.
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Sharlotta Cote, Alexis Ceecee Zhang, Victoria Ahmadzai, Amina Maleken, Christine Li, Jeremy Oppedisano, Kaavya Nair, Ljoudmila Busija & Laura E Downie. (2020) Intense pulsed light (IPL) therapy for the treatment of meibomian gland dysfunction. Cochrane Database of Systematic Reviews 2020:3.
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Sheng-nan Cheng, Fa-gang Jiang, Hua Chen, Hui Gao & Yu-kan Huang. (2019) Intense Pulsed Light Therapy for Patients with Meibomian Gland Dysfunction and Ocular Demodex Infestation. Current Medical Science 39:5, pages 800-809.
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Keyur Savla, Jimmy T Le & Andrew D Pucker. (2019) Tea tree oil for Demodex blepharitis. Cochrane Database of Systematic Reviews.
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