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Aerosol Science and Technology Volume 44, 2010 - Issue 9
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Regular Articles

Deposition of Inhaled Ultrafine Aerosols in Replicas of Nasal Airways of Infants

L. Golshahi Department of Mechanical Engineering, University of Alberta, Edmonton, Alberta, Canada
,
W. H. Finlay Department of Mechanical Engineering, University of Alberta, Edmonton, Alberta, Canada
,
J. S. Olfert Department of Mechanical Engineering, University of Alberta, Edmonton, Alberta, Canada
,
R. B. Thompson Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
&
M. L. Noga Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Alberta, Canada
Pages 741-752 | Received 20 Jan 2010, Accepted 10 Apr 2010, Published online: 13 Jul 2010

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P. Worth Longest, Karl Bass, Rabijit Dutta, Vijaya Rani, Morgan L. Thomas, Ahmad El-Achwah & Michael Hindle. (2019) Use of computational fluid dynamics deposition modeling in respiratory drug delivery. Expert Opinion on Drug Delivery 16:1, pages 7-26.
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Guilherme J. M. Garcia, Jeffry D. Schroeter & Julia S. Kimbell. (2015) Olfactory deposition of inhaled nanoparticles in humans. Inhalation Toxicology 27:8, pages 394-403.
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Kiao Inthavong, Qin Jiang Ge, Xiangdong Li & Ji Yuan Tu. (2013) Source and trajectories of inhaled particles from a surrounding environment and its deposition in the respiratory airway. Inhalation Toxicology 25:5, pages 280-291.
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Yue Zhou, Jinxiang Xi, Justin Simpson, Hammad Irshad & Yung-Sung Cheng. (2013) Aerosol Deposition in a Nasopharyngolaryngeal Replica of a 5-Year-Old Child. Aerosol Science and Technology 47:3, pages 275-282.
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Ajit Kumar, Agisilaos Kourmatzis, Hak-Kim Chan, Shaokoon Cheng & Gajendra Singh. (2024) Effect of transient inhalation on powder evacuation and dispersion in a typical dual air inlet dry powder inhaler. Journal of Aerosol Science 175, pages 106287.
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Feng Tao, Yu Feng, Baobin Sun, Jianwei Wang, Xiaole Chen & Jiarui Gong. (2022) Septoplasty Effect on the Enhancement of Airflow Distribution and Particle Deposition in Nasal Cavity: A Numerical Study. Healthcare 10:9, pages 1702.
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Karl Bass, Mohammad A. M. Momin, Connor Howe, Ghali Aladwani, Sarah Strickler, Arun V. Kolanjiyil, Michael Hindle, Robert M. DiBlasi & Worth Longest. (2022) Characterizing the Effects of Nasal Prong Interfaces on Aerosol Deposition in a Preterm Infant Nasal Model. AAPS PharmSciTech 23:5.
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Andrew R. MartinWarren H. Finlay. (2022) Empirical Deposition Correlations. Journal of Aerosol Medicine and Pulmonary Drug Delivery 35:3, pages 109-120.
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Fifi N. M. Elwekeel, Xinguang Cui & Antar M. M. Abdala. (2022) Effects of chlorine particle concentration on the human airway. Journal of Nanoparticle Research 24:6.
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Connor Howe, Mohammad A.M. Momin, Dale R. Farkas, Serena Bonasera, Michael Hindle & P. Worth Longest. (2021) Advancement of the Infant Air-Jet Dry Powder Inhaler (DPI): Evaluation of Different Positive-Pressure Air Sources and Flow Rates. Pharmaceutical Research 38:9, pages 1615-1632.
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Sana HosseiniTheodore A. SchumanLaleh Golshahi. (2021) Correlations to Estimate the Key Anatomical Dimensions of Pediatric Nasal Airways using Minimally Invasive Measurements of Intranasal Pressure Gradient. Journal of Aerosol Medicine and Pulmonary Drug Delivery 34:3, pages 171-180.
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Ayyoub Zouaghi & Noureddine Zouzou. (2020) Submicrometer Particle Penetration in a Miniature Dielectric Barrier Discharge type Electrostatic Precipitator. Submicrometer Particle Penetration in a Miniature Dielectric Barrier Discharge type Electrostatic Precipitator.
Xiaoyu Xu, Yidan Shang, Lin Tian, Wenguo Weng & Jiyuan Tu. (2018) A numerical study on firefighter nasal airway dosimetry of smoke particles from a realistic composite deck fire. Journal of Aerosol Science 123, pages 91-104.
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Karl Bass & P. Worth Longest. (2018) Development of an infant complete-airway in vitro model for evaluating aerosol deposition. Medical Engineering & Physics 58, pages 47-55.
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Scott Tavernini, Tanya K. Church, David A. Lewis, Andrew R. Martin & Warren H. Finlay. (2018) Scaling an idealized infant nasal airway geometry to mimic inertial filtration of neonatal nasal airways. Journal of Aerosol Science 118, pages 14-21.
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Agata Dorosz, Agata Penconek & Arkadiusz Moskal. (2016) In vitro study on the aerosol emitted from the DPI inhaler under two unsteady inhalation profiles. Journal of Aerosol Science 101, pages 104-117.
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O. Pourmehran, M. Rahimi-Gorji, M. Gorji-Bandpy & T.B. Gorji. (2015) Simulation of magnetic drug targeting through tracheobronchial airways in the presence of an external non-uniform magnetic field using Lagrangian magnetic particle tracking. Journal of Magnetism and Magnetic Materials 393, pages 380-393.
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Beth L. LaubeGail SharplessAmi R. VikaniVincent HarrandSimeon J. ZinreichKeith SedberryDarin KnausJames BarryMark Papania. (2015) Intranasal Deposition of Accuspray™ Aerosol in Anatomically Correct Models of 2-, 5-, and 12-Year-Old Children. Journal of Aerosol Medicine and Pulmonary Drug Delivery 28:5, pages 320-333.
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Nan-Hung Hsieh & Chung-Min Liao. (2014) In vitro measurement and dynamic modeling-based approaches for deposition risk assessment of inhaled aerosols in human respiratory system. Atmospheric Environment 95, pages 268-276.
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Nicholas B. CarrigyConor A. RuzyckiLaleh GolshahiWarren H. Finlay. (2014) Pediatric In Vitro and In Silico Models of Deposition via Oral and Nasal Inhalation . Journal of Aerosol Medicine and Pulmonary Drug Delivery 27:3, pages 149-169.
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Conor A. Ruzycki, Laleh Golshahi, Reinhard Vehring & Warren H. Finlay. (2014) Comparison of In Vitro Deposition of Pharmaceutical Aerosols in an Idealized Child Throat with In Vivo Deposition in the Upper Respiratory Tract of Children. Pharmaceutical Research 31:6, pages 1525-1535.
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Kiao Inthavong, Yidan Shang & Jiyuan Tu. (2014) Surface mapping for visualization of wall stresses during inhalation in a human nasal cavity. Respiratory Physiology & Neurobiology 190, pages 54-61.
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Agata Penconek & Arkadiusz Moskal. (2013) Deposition of diesel exhaust particles from various fuels in a cast of human respiratory system under two breathing patterns. Journal of Aerosol Science 63, pages 48-59.
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Jolyon P MitchellMark W Nagel. (2013) Improved laboratory test methods for orally inhaled products. Therapeutic Delivery 4:8, pages 1003-1026.
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E. Javaheri, L. Golshahi & W.H. Finlay. (2013) An idealized geometry that mimics average infant nasal airway deposition. Journal of Aerosol Science 55, pages 137-148.
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Jinxiang Xi, Ariel Berlinski, Yue Zhou, Bruce Greenberg & Xiawei Ou. (2012) Breathing Resistance and Ultrafine Particle Deposition in Nasal–Laryngeal Airways of a Newborn, an Infant, a Child, and an Adult. Annals of Biomedical Engineering 40:12, pages 2579-2595.
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Lev Ruzer & Naomi HarleyJacky Rosati, Kristin Isaacs & Ted Martonen. 2012. Aerosols Handbook. Aerosols Handbook 47 74 .
Guoguang Su & Ramana M. Pidaparti. (2011) Generating Nanoparticles for Respiratory Drug Delivery. Journal of Nanotechnology in Engineering and Medicine 2:3.
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L. Golshahi, M.L. Noga, R.B. Thompson & W.H. Finlay. (2011) In vitro deposition measurement of inhaled micrometer-sized particles in extrathoracic airways of children and adolescents during nose breathing. Journal of Aerosol Science 42:7, pages 474-488.
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