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Aerosol Science and Technology Volume 45, 2011 - Issue 1
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Regular Articles

Micronized Drug Adhesion and Detachment from Surfaces: Effect of Loading Conditions

Parthiban Selvam College of Pharmacy, University of Texas at Austin, Austin, Texas, USA
,
Steve Marek College of Pharmacy, University of Texas at Austin, Austin, Texas, USA
,
C. Randall Truman School of Engineering, University of New Mexico, Albuquerque, New Mexico, USA
,
Doug McNair Cerner Corporation, Kansas City, Kansas, USA
&
Hugh D.C. Smyth College of Pharmacy, University of Texas at Austin, Austin, Texas, USA
Pages 81-87 | Received 20 Apr 2010, Accepted 09 Aug 2010, Published online: 09 Jun 2011

Citations (17)

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Sachin Mane, Surendra Ponrathnam & Nayaku Chavan. (2016) Interfacial tension approach toward drug loading with two-dimensional crosslinked polymer embedded gold: Adsorption kinetics evaluation. International Journal of Polymeric Materials and Polymeric Biomaterials 65:4, pages 168-175.
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Swapnil S. Desai, Abhijeet A. Aher & Preeti T. Kadaskar. (2013) Methods for reduction of cohesive forces between carrier and drug in DPI formulation. Drug Development and Industrial Pharmacy 39:11, pages 1589-1598.
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Articles from other publishers (15)

Jie Feng, Cunteng Wang, Yi Zhang, Ka Chung Chan, Chun-Ho Liu, Christopher Y.H. Chao & Sau Chung Fu. (2023) Particle resuspension from a flow-induced fluttering flexible substrate. Powder Technology 415, pages 118163.
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Angela Ren, John J. KolengIIIIII, Mark Costello, Jamie E. Spahn, Hugh D.C. Smyth & Feng Zhang. (2023) Twin-Screw Continuous Mixing Can Produce Dry Powder Inhalation Mixtures for Pulmonary Delivery. Journal of Pharmaceutical Sciences 112:1, pages 272-281.
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Jamie E. Spahn, Amr Hefnawy, Hugh D.C. Smyth & Feng Zhang. (2022) Development of a novel method for the continuous blending of carrier-based dry powders for inhalation using a co-rotating twin-screw extruder. International Journal of Pharmaceutics 623, pages 121914.
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Jamie E. Spahn, Feng Zhang & Hugh D.C. Smyth. (2022) Mixing of dry powders for inhalation: A review. International Journal of Pharmaceutics 619, pages 121736.
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Laura Nižić Nodilo, Ivo Ugrina, Drago Špoljarić, Daniela Amidžić Klarić, Cvijeta Jakobušić Brala, Mirna Perkušić, Ivan Pepić, Jasmina Lovrić, Vesna Saršon, Maša Safundžić Kučuk, Dijana Zadravec, Livije Kalogjera & Anita Hafner. (2021) A Dry Powder Platform for Nose-to-Brain Delivery of Dexamethasone: Formulation Development and Nasal Deposition Studies. Pharmaceutics 13:6, pages 795.
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Piyush P. Mehta, Shivajirao S. Kadam & Atmaram P. Pawar. (2020) Exploring the impact of extrinsic lactose fines, a USP modified sampling device and modified centrifuge tube on the delivered dose uniformity and drug detachment performance of a fluticasone propionate dry powder inhaler. Journal of Drug Delivery Science and Technology 57, pages 101681.
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Piyush P. Mehta, Atmaram P. Pawar, Kakasaheb R. Mahadik, Shivajirao S. Kadam & Vividha Dhapte‐Pawar. 2020. Polymer Coatings. Polymer Coatings 41 74 .
Joana T. Pinto, Sandra Stranzinger, Andreas Kruschitz, Eva Faulhammer, Sven Stegemann, Eva Roblegg & Amrit Paudel. (2018) Insights into the processability and performance of adhesive blends of inhalable jet-milled and spray dried salbutamol sulphate at different drug loads. Journal of Drug Delivery Science and Technology 48, pages 466-477.
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Anthony J. Hickey. 2018. Particles and Nanoparticles in Pharmaceutical Products. Particles and Nanoparticles in Pharmaceutical Products 213 232 .
Jiecheng Yang, Chuan-Yu Wu & Michael Adams. (2015) DEM analysis of the effect of electrostatic interaction on particle mixing for carrier-based dry powder inhaler formulations. Particuology 23, pages 25-30.
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Bernice Mei Jin Tan, Celine Valeria Liew, Lai Wah Chan & Paul Wan Sia Heng. 2015. Pulmonary Drug Delivery. Pulmonary Drug Delivery 199 222 .
Sara Jaffari, Ben Forbes, Elizabeth Collins, Jiyi Khoo, Gary P Martin & Darragh Murnane. (2014) Evidence for the existence of powder sub-populations in micronized materials: Aerodynamic size-fractions of aerosolized powders possess distinct physicochemical properties.. Pharmaceutical Research 31:12, pages 3251-3264.
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Jiecheng Yang, Chuan-Yu Wu & Michael Adams. (2013) DEM analysis of particle adhesion during powder mixing for dry powder inhaler formulation development. Granular Matter 15:4, pages 417-426.
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Joseph KushnerIVIV. (2012) Incorporating Turbula mixers into a blending scale-up model for evaluating the effect of magnesium stearate on tablet tensile strength and bulk specific volume. International Journal of Pharmaceutics 429:1-2, pages 1-11.
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Martin J Donovan, Aileen Gibbons, Matthew J Herpin, Stephen Marek, Shayna L McGill & Hugh DC Smyth. (2011) Novel dry powder inhaler particle-dispersion systems. Therapeutic Delivery 2:10, pages 1295-1311.
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