Mathematical modeling and numerical simulation of surfactant delivery within a physical model of the neonatal trachea for different aerosol characteristics

E. GoikoetxeaThermal and Fluids Engineering Division, Mechanical Engineering Department, TECNUN, University of Navarra, San Sebastian, Gipuzkoa, SpainCorrespondence[email protected]

A. RivasThermal and Fluids Engineering Division, Mechanical Engineering Department, TECNUN, University of Navarra, San Sebastian, Gipuzkoa, Spain

X. MurgiaDepartment of Drug Delivery, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarland University, Saarbrücken, Germany

R. AntónThermal and Fluids Engineering Division, Mechanical Engineering Department, TECNUN, University of Navarra, San Sebastian, Gipuzkoa, Spain

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Federico Bianco, Fabrizio Salomone, Ilaria Milesi, Xabier Murgia, Sauro Bonelli, Elena Pasini, Raffaele Dellacà, Maria Luisa Ventura & Jane Pillow. (2021) Aerosol drug delivery to spontaneously-breathing preterm neonates: lessons learned. Respiratory Research 22:1.
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Francesco Tarantini, Ilaria Milesi, Xabier Murgia, Federico Bianco & Raffaele L. Dellacà. (2020) A Compartment-Based Mathematical Model for Studying Convective Aerosol Transport in Newborns Receiving Nebulized Drugs during Noninvasive Respiratory Support. Pharmaceutics 12:10, pages 936.
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Federico Bianco, Elena Pasini, Marcello Nutini, Xabier Murgia, Carolin Stoeckl, Martin Schlun, Uwe Hetzer, Sauro Bonelli, Marta Lombardini, Ilaria Milesi, Marisa Pertile, Stefan Minocchieri, Fabrizio Salomone & Albert Bucholski. (2020) In Vitro Performance of an Investigational Vibrating-Membrane Nebulizer with Surfactant under Simulated, Non-Invasive Neonatal Ventilation Conditions: Influence of Continuous Positive Airway Pressure Interface and Nebulizer Positioning on the Lung Dose. Pharmaceutics 12:3, pages 257.
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F. Bianco, F. Ricci, C. Catozzi, X. Murgia, M. Schlun, A. Bucholski, U. Hetzer, S. Bonelli, M. Lombardini, E. Pasini, M. Nutini, M. Pertile, S. Minocchieri, M. Simonato, B. Rosa, G. Pieraccini, G. Moneti, L. Lorenzini, S. Catinella, G. Villetti, M. Civelli, B. Pioselli, P. Cogo, V. Carnielli, C. Dani & F. Salomone. (2019) From bench to bedside: in vitro and in vivo evaluation of a neonate-focused nebulized surfactant delivery strategy. Respiratory Research 20:1.
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Iñigo Aramendia, Unai Fernandez-Gamiz, Alberto Lopez-Arraiza, Carmen Rey-Santano, Victoria Mielgo, Francisco Jose Basterretxea, Javier Sancho & Miguel Angel Gomez-Solaetxe. (2019) Experimental Evaluation of Perfluorocarbon Aerosol Generation with Two Novel Nebulizer Prototypes. Pharmaceutics 11:1, pages 19.
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Iñigo Aramendia, Unai Fernandez-Gamiz, Alberto Lopez-Arraiza, Carmen Rey-Santano, Victoria Mielgo, Francisco Basterretxea, Javier Sancho & Miguel Gomez-Solaetxe. (2018) Experimental and Numerical Modeling of Aerosol Delivery for Preterm Infants. International Journal of Environmental Research and Public Health 15:3, pages 423.
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Mathematical modeling and numerical simulation of surfactant delivery within a physical model of the neonatal trachea for different aerosol characteristics

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Mathematical modeling and numerical simulation of surfactant delivery within a physical model of the neonatal trachea for different aerosol characteristics

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