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Journal of Psychoactive Drugs Volume 51, 2019 - Issue 1
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Article

Long-Term Cognitive Effects of Kratom (Mitragyna speciosa Korth.) Use

Darshan Singh Ph.D.Centre for Drug Research, Universiti Sains Malaysia, Penang, MalaysiaCorrespondence[email protected]
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,
Suresh Narayanan Ph.D.School of Social Sciences, Universiti Sains Malaysia, Penang, MalaysiaView further author information
,
Christian P. Müller Ph.D.Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, GermanyView further author information
,
Balasingam Vicknasingam Ph.D.Centre for Drug Research, Universiti Sains Malaysia, Penang, MalaysiaView further author information
,
Murat Yücel Ph.D.Laboratory for Brain and Mental Health, Monash Institute of Cognitive and Clinical Neurosciences and School of Psychological Sciences, Monash University, Clayton, VIC, AustraliaView further author information
,
Eric Tatt Wei Ho Ph.D.Center for Intelligent Signal & Imaging Research, Universiti Teknologi Petronas, Perak, MalaysiaView further author information
,
Zurina Hassan Ph.D.Centre for Drug Research, Universiti Sains Malaysia, Penang, MalaysiaView further author information
&
Sharif Mahsufi Mansor Ph.D.Centre for Drug Research, Universiti Sains Malaysia, Penang, MalaysiaView further author information
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Pages 19-27 | Received 20 Apr 2018, Accepted 30 Jul 2018, Published online: 15 Dec 2018

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Darika Saingam, Darshan Singh, Alan F. Geater, Sawitri Assanangkornchai, Walailuk Jitpiboon & Carl Latkin. (2023) The Health Impact of Long-Term Kratom (Mitragyna Speciosa) Use in Southern Thailand. Substance Use & Misuse 58:10, pages 1212-1225.
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Charles Veltri & Oliver Grundmann. (2019) Current perspectives on the impact of Kratom use. Substance Abuse and Rehabilitation 10, pages 23-31.
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Anil K. Bachu, Prakamya Singal, Brittany Griffin, Lauren Harbaugh, Sakshi Prasad, Lakshit Jain, Syed Mohiuddin, Bhavani Nagendra Papudesi, Tarika Nagi, Nagy A. Youssef, Amit Chopra & Saeed Ahmed. Kratom use and mental health: A systematic literature review and case example. Journal of Addictive Diseases 0:0, pages 1-12.
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Articles from other publishers (30)

Nur Aisyah Khairul Annuar, Ummi Kalthum Azlan, Ahmed Mediani, Xiaohui Tong, Rongchun Han, Ebtesam Al-Olayan, Syarul Nataqain Baharum, Hamidun Bunawan, Murni Nazira Sarian, Hamizah Shahirah Hamezah & Ibrahim Jantan. (2024) An insight review on the neuropharmacological effects, mechanisms of action, pharmacokinetics and toxicity of mitragynine. Biomedicine & Pharmacotherapy 171, pages 116134.
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Suleiman Yunusa, Zurina Hassan & Christian P. Müller. (2023) Mitragynine inhibits hippocampus neuroplasticity and its molecular mechanism. Pharmacological Reports 75:6, pages 1488-1501.
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Rahni Hossain, Abida Sultana, Manit Nuinoon, Kunwadee Noonong, Jitbanjong Tangpong, Kazi Helal Hossain & Md Atiar Rahman. (2023) A Critical Review of the Neuropharmacological Effects of Kratom: An Insight from the Functional Array of Identified Natural Compounds. Molecules 28:21, pages 7372.
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Bin Yang, Shanyong Yi, Ruiling Zhang & Mohammad Farris Iman Leong Abdullah. (2023) Adverse Psychological and Therapeutic Effects of Kratom (Mitragyna speciosa) Use: A Systematic Review. Malaysian Journal of Medicine and Health Sciences 19:5, pages 218-236.
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Rima Atria Japarin, Norsyifa Harun, Zurina Hassan & Christian P. Müller. (2023) The dopamine D1 receptor antagonist SCH-23390 blocks the acquisition, but not expression of mitragynine-induced conditioned place preference in rats. Behavioural Brain Research 453, pages 114638.
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Elisabeth Prevete, Kim Paula Colette Kuypers, Eef Lien Theunissen, Gianluca Esposito, Johannes Gerardus Ramaekers, Massimo Pasquini & Ornella Corazza. (2023) Clinical Implications of Kratom (Mitragyna speciosa) Use: a Literature Review. Current Addiction Reports 10:2, pages 317-334.
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Rima Atria Japarin, Norsyifa Harun, Zurina Hassan & Mohammed Shoaib. (2023) Mitragynine, a primary constituent of kratom reinstates morphine-seeking behaviour in rats. Behavioural Pharmacology 34:2-3, pages 123-130.
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David Peran, Michael Stern, Petr Cernohorsky, Roman Sykora, Stanislav Popela & Frantisek Duska. (2023) Mitragyna speciosa (Kratom) poisoning: Findings from ten cases. Toxicon 225, pages 107054.
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Mohamad Azmeer Effendy, Suleiman Yunusa, Noorul Hamizah Mat, Ahmad Tarmizi Che Has, Christian P. Müller & Zurina Hassan. (2023) The role of AMPA and NMDA receptors in mitragynine effects on hippocampal synaptic plasticity. Behavioural Brain Research 438, pages 114169.
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Wanumaidah Saengmolee, Dania Cheaha, Nusaib Sa-ih & Ekkasit Kumarnsit. (2022) Exploring of cardiac autonomic activity with heart rate variability in long-term kratom ( Mitragyna speciosa Korth.) users: a preliminary study . PeerJ 10, pages e14280.
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Chad HartleyIIII, Marilyn Bulloch & Scott R. Penzak. (2022) Clinical Pharmacology of the Dietary Supplement Kratom ( Mitragyna speciosa ) . The Journal of Clinical Pharmacology 62:5, pages 577-593.
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Vinita Sharma, Linda B. Cottler, Cristina B. Bares & Catalina Lopez-Quintero. (2022) Kratom Use Among U.S. Adolescents: Analyses of the 2019 National Survey on Drug Use and Health. Journal of Adolescent Health 70:4, pages 677-681.
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American Psychiatric Association. 2022. Diagnostic and Statistical Manual of Mental Disorders. Diagnostic and Statistical Manual of Mental Disorders.
Wanumaidah Saengmolee, Rattanaphon Chaisaen, Phairot Autthasan, Chutimon Rungsilp, Nusaib Sa-Ih, Dania Cheaha, Ekkasit Kumarnsit & Theerawit Wilaiprasitporn. (2022) Consumer-Grade Brain Measuring Sensor in People With Long-Term Kratom Consumption. IEEE Sensors Journal 22:6, pages 6088-6097.
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Inna Larsen, Emily Zhang & Pantea Farahmand. (2022) Current Understanding of the Effects and Potential Clinical Utility of Kratom: A Review. Journal of Psychiatric Practice 28:2, pages 92-97.
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Jack E. Henningfield, Daniel W. Wang & Marilyn A. Huestis. (2022) Kratom Abuse Potential 2021: An Updated Eight Factor Analysis. Frontiers in Pharmacology 12.
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Shaun L. Greene. 2022. Novel Psychoactive Substances. Novel Psychoactive Substances 495 532 .
Chiek Yi You, Zurina Hassan, Christian P. Müller & Farah Wahida Suhaimi. (2021) Mitragynine improves cognitive performance in morphine-withdrawn rats. Psychopharmacology 239:1, pages 313-325.
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Elisabeth Prevete, Kim Paula Colette Kuypers, Eef Lien Theunissen, Ornella Corazza, Giuseppe Bersani & Johannes Gerardus Ramaekers. (2021) A systematic review of (pre)clinical studies on the therapeutic potential and safety profile of kratom in humans. Human Psychopharmacology: Clinical and Experimental 37:1.
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Mohammad Farris Iman Leong Bin Abdullah & Darshan Singh. (2021) The Adverse Cardiovascular Effects and Cardiotoxicity of Kratom (Mitragyna speciosa Korth.): A Comprehensive Review. Frontiers in Pharmacology 12.
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Elisabeth Müller, Thomas Hillemacher & Christian P. Müller. (2021) Kratom use for depression/anxiety self-management: challenges during the COVID-19 pandemic – A case report. Heliyon 7:5, pages e07039.
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Farah Wahida Suhaimi, Zurina Hassan, Sharif Mahsufi Mansor & Christian P. Müller. (2021) The effects of chronic mitragynine (Kratom) exposure on the EEG in rats. Neuroscience Letters 745, pages 135632.
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Pietro Brunetti, Alfredo Fabrizio Lo Faro, Anastasio Tini, Francesco Paolo Busardò & Jeremy Carlier. (2020) Pharmacology of Herbal Sexual Enhancers: A Review of Psychiatric and Neurological Adverse Effects. Pharmaceuticals 13:10, pages 309.
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Elisabeth Müller, Thomas Hillemacher & Christian P. Müller. (2020) Kratom instrumentalization for severe pain self-treatment resulting in addiction – A case report of acute and chronic subjective effects. Heliyon 6:7, pages e04507.
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Steven C. Eastlack, Elyse M. Cornett & Alan D. Kaye. (2020) Kratom—Pharmacology, Clinical Implications, and Outlook: A Comprehensive Review. Pain and Therapy 9:1, pages 55-69.
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Rahimah Hassan, Cheah Pike See, Sasidharan Sreenivasan, Sharif M. Mansor, Christian P. Müller & Zurina Hassan. (2020) Mitragynine Attenuates Morphine Withdrawal Effects in Rats—A Comparison With Methadone and Buprenorphine. Frontiers in Psychiatry 11.
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Rhiannon Bath, Tanner Bucholz, Amy F. Buros, Darshan Singh, Kirsten E. Smith, Charles A. Veltri & Oliver Grundmann. (2020) Self-reported Health Diagnoses and Demographic Correlates With Kratom Use: Results From an Online Survey. Journal of Addiction Medicine 14:3, pages 244-252.
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C Michael White. (2019) Pharmacologic and clinical assessment of kratom: An update. American Journal of Health-System Pharmacy 76:23, pages 1915-1925.
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John M Corkery, Peter Streete, Hugh Claridge, Christine Goodair, Duccio Papanti, Laura Orsolini, Fabrizio Schifano, Kanav Sikka, Sophie Körber & Amy Hendricks. (2019) Characteristics of deaths associated with kratom use. Journal of Psychopharmacology 33:9, pages 1102-1123.
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Vânia Meireles, Tiago Rosado, Mário Barroso, Sofia Soares, Joana Gonçalves, Ângelo Luís, Débora Caramelo, Ana Simão, Nicolás Fernández, Ana Duarte & Eugenia Gallardo. (2019) Mitragyna speciosa: Clinical, Toxicological Aspects and Analysis in Biological and Non-Biological Samples. Medicines 6:1, pages 35.
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