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ORIGINAL ARTICLE

Effect of timing of surgery on survival after preoperative hyperfractionated accelerated radiotherapy (HART) for locally advanced rectal cancer (LARC): Is it a matter of days?

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Pages 1086-1093 | Received 30 Mar 2006, Published online: 08 Jul 2009

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Bengt Glimelius. (2006) Rectal cancer irradiation. Long course, short course or something else?. Acta Oncologica 45:8, pages 1013-1017.
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Xiang Cheng, Hongji Zhang, Ahmad Hamad, Hai Huang & Allan Tsung. (2022) Surgery-mediated tumor-promoting effects on the immune microenvironment. Seminars in Cancer Biology 86, pages 408-419.
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Kendrick Koo, Rachel Ward, Ryan L. Smith, Jeremy Ruben, Peter W. G. Carne & Hany Elsaleh. (2021) Temporal determinants of tumour response to neoadjuvant rectal radiotherapy. PLOS ONE 16:6, pages e0254018.
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Robin Detering, Wernard A. A. Borstlap, Lisa Broeders, Linda Hermus, Corrie A. M. Marijnen, Regina G. H. Beets-Tan, Willem A. Bemelman, Henderik L. van Westreenen & Pieter J. Tanis. (2018) Cross-Sectional Study on MRI Restaging After Chemoradiotherapy and Interval to Surgery in Rectal Cancer: Influence on Short- and Long-Term Outcomes. Annals of Surgical Oncology 26:2, pages 437-448.
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Min Jung Kim, Jin Suk Cho, Eun Mi Kim, Woo Ah Ko & Jae Hwan Oh. (2018) Optimal Time Interval for Surgery After Neoadjuvant Chemoradiotherapy in Patients With Locally Advanced Rectal Cancer: Analysis of Health Insurance Review and Assessment Service Data. Annals of Coloproctology 34:5, pages 241-247.
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Sea-Won Lee, Jong Hoon Lee, In Kyu Lee, Seong Taek Oh, Dae Yong Kim, Tae Hyun Kim, Jae Hwan Oh, Ji Yeon Baek, Hee Jin Chang, Hee Chul Park, Hee Cheol Kim, Eui Kyu Chie, Taek-Keun Nam & Hong Seok Jang. (2018) The Impact of Surgical Timing on Pathologic Tumor Response after Short Course and Long Course Preoperative Chemoradiation for Locally Advanced Rectal Adenocarcinoma. Cancer Research and Treatment 50:3, pages 1039-1050.
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Zeynep Gural, Sezer Saglam, Serap Yucel, Esra Kaytan-Saglam, Oktar Asoglu, Cetin Ordu, Hediye Acun, Rasul Sharifov, Semen Onder, Ahmet Kizir & Ethem N Oral. (2018) Neoadjuvant hyperfractionated accelerated radiotherapy plus concomitant 5-fluorouracil infusion in locally advanced rectal cancer: A phase II study. World Journal of Gastrointestinal Oncology 10:1, pages 40-47.
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Luis De La Maza, Matthew Wu, Licun Wu, Hana Yun, Yidan Zhao, Mark Cattral, Andrea McCart, BC John Cho & Marc de Perrot. (2017) In Situ Vaccination after Accelerated Hypofractionated Radiation and Surgery in a Mesothelioma Mouse Model . Clinical Cancer Research 23:18, pages 5502-5513.
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Natacha Leroi, François Lallemand, Philippe Coucke, Agnès Noel & Philippe Martinive. (2016) Impacts of Ionizing Radiation on the Different Compartments of the Tumor Microenvironment. Frontiers in Pharmacology 7.
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Ali Akbar, Abu Bakar Hafeez Bhatti, Samiullah Khan Niazi, Amir Ali Syed, Shahid Khattak, Syed Hassan Raza & Ather Saeed Kazmi. (2016) Impact of Time Interval Between Chemoradiation and Surgery on Pathological Complete Response and Survival in Rectal Cancer. Asian Pacific Journal of Cancer Prevention 17:1, pages 89-93.
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Natacha Leroi, Nor Eddine Sounni, Eva Van Overmeire, Silvia Blacher, Raphael Marée, Jo Van Ginderachter, François Lallemand, Eric Lenaerts, Philippe Coucke, Agnès Noel & Philippe Martinive. (2015) The timing of surgery after neoadjuvant radiotherapy influences tumor dissemination in a preclinical model. Oncotarget 6:34, pages 36825-36837.
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Bengt Glimelius. (2014) Optimal Time Intervals between Pre-Operative Radiotherapy or Chemoradiotherapy and Surgery in Rectal Cancer?. Frontiers in Oncology 4.
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Hiroshi Doi, Naohito Beppu, Soichi Odawara, Masao Tanooka, Yasuhiro Takada, Yasue Niwa, Masayuki Fujiwara, Fumihiko Kimura, Hidenori Yanagi, Naoki Yamanaka, Norihiko Kamikonya & Shozo Hirota. (2013) Neoadjuvant short-course hyperfractionated accelerated radiotherapy (SC-HART) combined with S-1 for locally advanced rectal cancer. Journal of Radiation Research 54:6, pages 1118-1124.
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Chia Bin Fang, Caroline Merci Caliari de Neves Gomes, Fernanda Bellotti Formiga, Vanessa Antunes Fonseca, Marineide Prudencio Carvalho & Wilmar Artur Klug. (2013) Existem benefícios com a cirurgia retardada após radioterapia e quimioterapia neoadjuvante no câncer de reto localmente avançado?. ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) 26:1, pages 31-35.
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Robert Glynne-Jones & Miranda Kronfli. (2011) Locally Advanced Rectal Cancer. Drugs 71:9, pages 1153-1177.
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S. Gollins. (2010) Radiation, chemotherapy and biological therapy in the curative treatment of locally advanced rectal cancer. Colorectal Disease 12, pages 2-24.
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Rainer Kube, Henry Ptok, David Jacob, Jörg Fahlke, Pawel Mroczkowski, Hans Lippert, Gunther Ziegenhardt, Uwe Schmidt & Ingo Gastinger. (2009) Modified neoadjuvant short-course radiation therapy in uT3 rectal carcinoma: low local recurrence rate with unchanged overall survival and frequent morbidity. International Journal of Colorectal Disease 25:1, pages 109-117.
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