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ORIGINAL ARTICLE

The in vitro anti-tumour activity of zoledronic acid and docetaxel at clinically achievable concentrations in prostate cancer

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Pages 669-677 | Received 22 May 2006, Published online: 08 Jul 2009

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Michele Caraglia, Monica Marra, Silvio Naviglio, Gerardo Botti, Raffaele Addeo & Alberto Abbruzzese. (2010) Zoledronic acid: an unending tale for an antiresorptive agent. Expert Opinion on Pharmacotherapy 11:1, pages 141-154.
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Articles from other publishers (27)

Andrea Christou, Nuno Ferreira & Antonia Sophocleous. (2022) Effects of zoledronic acid on osteosarcoma progression and metastasis: systematic review and meta‐analysis. Clinical and Experimental Medicine 23:7, pages 3041-3051.
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Aidan Kane, Leona Campbell, Diana Ky, David Hibbs & Dee Carter. (2021) The Antifungal and Synergistic Effect of Bisphosphonates in Cryptococcus . Antimicrobial Agents and Chemotherapy 65:2.
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Rachel M. Jones, Claire Morgan & Gianfilippo Bertelli. (2015) Effects of zoledronic acid and docetaxel on small GTP-binding proteins in prostate cancer. Tumor Biology 36:6, pages 4861-4869.
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Umut Varol, Mustafa Degirmenci, Burcak Karaca, Harika Atmaca, Asli Kisim, Selim Uzunoglu, Canfeza Sezgin, Ulus Ali Sanli & Ruchan Uslu. (2014) Zoledronic acid increases cytotoxicity by inducing apoptosis in hormone and docetaxel-resistant prostate cancer cell lines. Tumor Biology 36:2, pages 779-786.
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Iris Chiara Salaroglio, Ivana Campia, Joanna Kopecka, Elena Gazzano, Sara Orecchia, Dario Ghigo & Chiara Riganti. (2014) Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma. Oncotarget 6:2, pages 1128-1142.
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Chiara Riganti, Barbara Castella, Joanna Kopecka, Ivana Campia, Marta Coscia, Gianpiero Pescarmona, Amalia Bosia, Dario Ghigo & Massimo Massaia. (2013) Zoledronic Acid Restores Doxorubicin Chemosensitivity and Immunogenic Cell Death in Multidrug-Resistant Human Cancer Cells. PLoS ONE 8:4, pages e60975.
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Tilman Todenhöfer, Jörg Hennenlotter, Ursula Kühs, Valentina Gerber, Georgios Gakis, Ulrich Vogel, Stefan Aufderklamm, Axel Merseburger, Judith Knapp, Arnulf Stenzl & Christian Schwentner. (2012) Altered expression of farnesyl pyrophosphate synthase in prostate cancer: evidence for a role of the mevalonate pathway in disease progression?. World Journal of Urology 31:2, pages 345-350.
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Jean-Baptiste Lattouf & Fred Saad. 2013. Prostate Cancer: A Comprehensive Perspective. Prostate Cancer: A Comprehensive Perspective 935 940 .
H K Koul, S Koul & R B Meacham. (2011) New role for an established drug? Bisphosphonates as potential anticancer agents. Prostate Cancer and Prostatic Diseases 15:2, pages 111-119.
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Y. Loriot, C. Massard & K. Fizazi. (2012) Recent developments in treatments targeting castration-resistant prostate cancer bone metastases. Annals of Oncology 23:5, pages 1085-1094.
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KOJIRO YANO. (2012) Lipid metabolic pathways as lung cancer therapeutic targets: A computational study. International Journal of Molecular Medicine 29:4, pages 519-529.
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Matti Aapro & Fred Saad. (2012) Bone-modifying agents in the treatment of bone metastases in patients with advanced genitourinary malignancies: a focus on zoledronic acid. Therapeutic Advances in Urology 4:2, pages 85-101.
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Susanta K. Hui, Gregory R. Fairchild, Louis S. Kidder, Manju Sharma, Maryka Bhattacharya, Scott Jackson, Chap Le & Douglas Yee. (2011) Skeletal Remodeling Following Clinically Relevant Radiation-Induced Bone Damage Treated with Zoledronic Acid. Calcified Tissue International 90:1, pages 40-49.
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Fred Saad & Jean-Baptiste Lattouf. 2012. Prevention of Bone Metastases. Prevention of Bone Metastases 109 126 .
Joaquim Bosch-Barrera, Sofía D. Merajver, Javier A. Menéndez & Catherine Van Poznak. (2011) Direct antitumour activity of zoledronic acid: preclinical and clinical data. Clinical and Translational Oncology 13:3, pages 148-155.
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Jinlu Dai, Yi Lu, Chunyan Yu, Jill M. Keller, Atsushi Mizokami, Jian Zhang & Evan T. Keller. (2010) Reversal of Chemotherapy-Induced Leukopenia Using Granulocyte Macrophage Colony-Stimulating Factor Promotes Bone Metastasis That Can Be Blocked with Osteoclast Inhibitors. Cancer Research 70:12, pages 5014-5023.
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Helen L. Neville-Webbe, Michael Gnant & Robert E. Coleman. (2010) Potential Anticancer Properties of Bisphosphonates. Seminars in Oncology 37, pages S53-S65.
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Fred Saad & James Eastham. (2010) Maintaining Bone Health in Prostate Cancer Throughout the Disease Continuum. Seminars in Oncology 37, pages S30-S37.
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H.L. Neville-Webbe & R.E. Coleman. (2010) Bisphosphonates and RANK ligand inhibitors for the treatment and prevention of metastatic bone disease. European Journal of Cancer 46:7, pages 1211-1222.
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Robert Segal, Fadi Brimo & Wassim Kassouf. (2010) Normalization of Prostate-Specific Antigen and Reduction of Clinical Metastasis Following Zoledronic Acid Treatment in Castrate-Resistant Prostate Cancer. UroToday International Journal 03:01.
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Stephen S. Grubbs & Charles J. Schneider. 2009. Bone and Cancer. Bone and Cancer 219 227 .
John M. Fitzpatrick, Marc Colombel, Fred Saad, Cora N. Sternberg & Andrea Tubaro. (2009) Treatment Strategies in Advanced Prostate Cancer/Genitourinary Malignancies: The Use of Bisphosphonates Across the Continuum. European Urology Supplements 8:9, pages 733-737.
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Hervé Nyangoga, Stéphane Blouin, Hélène Libouban, Michel Félix Baslé & Daniel Chappard. (2009) A single pretreatment by zoledronic acid converts metastases from osteolytic to osteoblastic in the rat. Microscopy Research and Technique, pages NA-NA.
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Francesco Fabbri, Giovanni Brigliadori, Silvia Carloni, Paola Ulivi, Ivan Vannini, Anna Tesei, Rosella Silvestrini, Dino Amadori & Wainer Zoli. (2008) Zoledronic acid increases docetaxel cytotoxicity through pMEK and Mcl-1 inhibition in a hormone-sensitive prostate carcinoma cell line. Journal of Translational Medicine 6:1.
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Panagiotis Tsagozis, Fredrik Eriksson & Pavel Pisa. (2008) Zoledronic acid modulates antitumoral responses of prostate cancer-tumor associated macrophages. Cancer Immunology, Immunotherapy 57:10, pages 1451-1459.
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Daniele Santini, Sara Galluzzo, Maria Elisabetta Fratto, Bruno Vincenzi, Silvia Angeletti, Giordano Dicuonzo, Gaia Schiavon & Giuseppe Tonini. (2008) Bisphosphonates: from preclinical evidence to survival data in the oncologic setting. Oncology Reviews 1:3, pages 141-151.
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Yonghui Zhang, Michael P. Hudock, Kilannin Krysiak, Rong Cao, Kyle Bergan, Fenglin Yin, Annette Leon & Eric Oldfield. (2007) Activity of Sulfonium Bisphosphonates on Tumor Cell Lines. Journal of Medicinal Chemistry 50:24, pages 6067-6079.
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