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ORIGINAL ARTICLES: CANCER DIAGNOSTICS AND PROGNOSTICS

Circulating tumor DNA as a marker of minimal residual disease following local treatment of metastases from colorectal cancer

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Pages 1424-1429 | Received 12 Jan 2020, Accepted 01 Aug 2020, Published online: 13 Aug 2020

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Louise Bach Callesen, Torben Frøstrup Hansen, Rikke Fredslund Andersen, Niels Pallisgaard, Stine Kramer, Sven Schlander, Søren Rafael Rafaelsen, Anders Kindberg Boysen, Lars Henrik Jensen, Anders Jakobsen & Karen-Lise Garm Spindler. (2023) ctDNA-guided adjuvant treatment after radical-intent treatment of metastatic spread from colorectal cancer—the first interim results from the OPTIMISE study. Acta Oncologica 62:12, pages 1742-1748.
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Louise Bach Callesen, Torben Frøstrup Hansen, Rikke Fredslund Andersen, Niels Pallisgaard, Stine Kramer, Sven Schlander, Søren Rafael Rafaelsen, Anders Kindberg Boysen, Lars Henrik Jensen, Anders Jakobsen & Karen-Lise Garm Spindler. (2022) OPTIMISE: Optimisation of treatment selection and follow-up in oligometastatic colorectal cancer – a ctDNA-guided phase II randomised approach. Study protocol. Acta Oncologica 61:9, pages 1152-1156.
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Tom Boeken, Hélène Blons, Carole Dean, Marc Sapoval & Olivier Pellerin. (2023) The potential of ctDNA in locoregional therapies for colorectal cancer. The Lancet Gastroenterology & Hepatology 8:12, pages 1072-1073.
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Da Wang, Penglai Zhao, Tingting Lu, Jingyao Ren, Lihui Zhu, Xiaoyong Han, Guangming Zhang, Xiaohua Dong, Haizhong Ma, Miao Yu & Hui Cai. (2023) ctDNA as a prognostic biomarker in resectable CLM: Systematic review and meta-analysis. Open Life Sciences 18:1.
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Alexandre A. Jácome & Benny Johnson. (2023) Minimal Residual Disease in Colorectal Cancer: Are We Finding the Needle in a Haystack?. Cells 12:7, pages 1068.
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Dominik Paul Modest, Meinolf Karthaus, Stefan Kasper, Nicolas Moosmann, Verena Keitel, Alexander Kiani, Jens Uhlig, Lutz Jacobasch, Ludwig Fischer v. Weikersthal, Martin Fuchs, Florian Kaiser, Christian Lerchenmüller, Dagmar Sent, Christian Junghanß, Swantje Held, Sylvie Lorenzen, Klaus Kaczirek, Andreas Jung, Sebastian Stintzing & Volker Heinemann. (2022) FOLFOX plus panitumumab or FOLFOX alone as additive therapy following R0/1 resection of RAS wild-type colorectal cancer liver metastases – The PARLIM trial (AIO KRK 0314). European Journal of Cancer 173, pages 297-306.
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Manqi Wu, Haifeng Shen, Ziyang Wang, Nnennaya Kanu & Kezhong Chen. (2022) Research Progress on Postoperative Minimal/Molecular Residual Disease Detection in Lung Cancer. Chronic Diseases and Translational Medicine 8:2, pages 83-90.
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Louise B. Callesen, Tana Takacova, Julian Hamfjord, Florian Würschmidt, Karl J. Oldhafer, Roland Brüning, Dirk Arnold & Karen-Lise G. Spindler. (2022) Circulating DNA in patients undergoing loco-regional treatment of colorectal cancer metastases: a systematic review and meta-analysis. Therapeutic Advances in Medical Oncology 14, pages 175883592211331.
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Lisa S.M. Hofste, Maartje J. Geerlings, Eveline J. Kamping, Nadine D.H. Kouwenhoven, Daniel von Rhein, Erik A.M. Jansen, Linda M. Garms, Iris D. Nagtegaal, Rachel S. van der Post, Johannes H.W. de Wilt, Bastiaan R. Klarenbeek & Marjolijn J.L. Ligtenberg. (2022) Clinical Validity of Tumor-Informed Circulating Tumor DNA Analysis in Patients Undergoing Surgery of Colorectal Metastases. Diseases of the Colon & Rectum Publish Ahead of Print.
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Rebecca A. Snyder, Arvind Dasari & Y. Nancy You. 2022. Colorectal Liver Metastasis. Colorectal Liver Metastasis 457 464 .
Apurva Bonde, Daniel A. Smith, Elias Kikano, Jennifer M. Yoest, Sree H. Tirumani & Nikhil H. Ramaiya. (2021) Overview of serum and tissue markers in colorectal cancer: a primer for radiologists. Abdominal Radiology 46:12, pages 5521-5535.
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Yue Wang, Chunxia Yang, Wenjing Li, Ying Shen, Jianzhong Deng, Wenbin Lu, Jianhua Jin, Yongping Liu & Qian Liu. (2021) Identification of colon tumor marker NKD1 via integrated bioinformatics analysis and experimental validation. Cancer Medicine 10:20, pages 7383-7394.
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Jun Gong, Andrew Hendifar, Alexandra Gangi, Karen Zaghiyan, Katelyn Atkins, Yosef Nasseri, Zuri Murrell, Jane C. Figueiredo, Sarah Salvy, Robert Haile & Megan Hitchins. (2021) Clinical Applications of Minimal Residual Disease Assessments by Tumor-Informed and Tumor-Uninformed Circulating Tumor DNA in Colorectal Cancer. Cancers 13:18, pages 4547.
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Karen Bolhuis, Iris van 't Erve, Clinton Mijnals, Pien M. Delis – Van Diemen, Joost Huiskens, Aysun Komurcu, Marta Lopez-Yurda, Daan van den Broek, Rutger-Jan Swijnenburg, Gerrit A. Meijer, Cornelis J.A. Punt & Remond J.A. Fijneman. (2021) Postoperative circulating tumour DNA is associated with pathologic response and recurrence-free survival after resection of colorectal cancer liver metastases. EBioMedicine 70, pages 103498.
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Andreas Koulouris, Christos Tsagkaris, Ippokratis Messaritakis, Nikolaos Gouvas, Maria Sfakianaki, Maria Trypaki, Vasiliki Spyrou, Manousos Christodoulakis, Elias Athanasakis, Evangelos Xynos, Maria Tzardi, Dimitrios Mavroudis & John Souglakos. (2021) Resectable Colorectal Cancer: Current Perceptions on the Correlation of Recurrence Risk, Microbiota and Detection of Genetic Mutations in Liquid Biopsies. Cancers 13:14, pages 3522.
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Anna C. Lefèvre, Niels Pallisgaard, Camilla Kronborg, Karen L. Wind, Søren R. P. Krag & Karen-Lise G. Spindler. (2021) The Clinical Value of Measuring Circulating HPV DNA during Chemo-Radiotherapy in Squamous Cell Carcinoma of the Anus. Cancers 13:10, pages 2451.
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