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Current Medical Research and Opinion Volume 32, 2016 - Issue 11
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Oncology

The strange connection between epidermal growth factor receptor tyrosine kinase inhibitors and dapsone: from rash mitigation to the increase in anti-tumor activity

Mariarosaria BoccellinoDepartment of Biochemistry, Biophysics and General Pathology, Second University of Naples, Naples, Italy;
,
Lucio QuagliuoloDepartment of Biochemistry, Biophysics and General Pathology, Second University of Naples, Naples, Italy;
,
Concetta AlaiaDepartment of Biochemistry, Biophysics and General Pathology, Second University of Naples, Naples, Italy;
,
Anna GrimaldiDepartment of Biochemistry, Biophysics and General Pathology, Second University of Naples, Naples, Italy;
,
Raffaele AddeoOncology DH ASL Napoli 3 Nord, Frattamaggiore Hospital, Frattamaggiore, Naples, Italy;
,
Giovanni Francesco NicolettiMedical–Surgical and Dental Specialities, Second University of Naples, Naples, Italy;
,
Richard Eric KastIIAIGC Study Center, VT, USA
&
Michele CaragliaDepartment of Biochemistry, Biophysics and General Pathology, Second University of Naples, Naples, Italy; Correspondence[email protected], [email protected]
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Pages 1839-1848 | Received 12 May 2016, Accepted 07 Jul 2016, Published online: 11 Aug 2016

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R. E. Kast. (2020) Dapsone as treatment adjunct in ARDS. Experimental Lung Research 46:5, pages 157-161.
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Articles from other publishers (14)

Griselda Cabral‑Pacheco, Virginia Flores‑Morales, Idalia Garza‑Veloz, Miriam Damián‑Sandoval, Rosa Martínez‑Flores, María Martínez‑Vázquez, Iván Delgado‑Enciso, Iram Rodriguez‑Sanchez & Margarita Martinez‑Fierro. (2023) Evaluation of dapsone and its synthetic derivative DDS‑13 in cancer in vitro . Experimental and Therapeutic Medicine 27:1.
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Richard E. Kast, Alex Alfieri, Hazem I. Assi, Terry C. Burns, Ashraf M. Elyamany, Maria Gonzalez-Cao, Georg Karpel-Massler, Christine Marosi, Michael E. Salacz, Iacopo Sardi, Pieter Van Vlierberghe, Mohamed S. Zaghloul & Marc-Eric Halatsch. (2022) MDACT: A New Principle of Adjunctive Cancer Treatment Using Combinations of Multiple Repurposed Drugs, with an Example Regimen. Cancers 14:10, pages 2563.
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Badar A. Kanwar, Asif Khattak, Jenny Balentine, Jong Hoon Lee & Richard E. Kast. (2022) Benefits of Using Dapsone in Patients Hospitalized with COVID-19. Vaccines 10:2, pages 195.
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Mariarosaria Boccellino, Giovanni Galasso, Pasqualina Ambrosio, Paola Stiuso, Stefania Lama, Erika Di Zazzo, Sonia Schiavon, Daniele Vecchio, Luca D’ambrosio, Lucio Quagliuolo, Antonia Feola, Giacomo Frati & Marina Di Domenico. (2021) H9c2 Cardiomyocytes under Hypoxic Stress: Biological Effects Mediated by Sentinel Downstream Targets. Oxidative Medicine and Cellular Longevity 2021, pages 1-10.
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R.E. Kast, T.C. Burns & M.-E. Halatsch. (2021) Short review of SEC, a potential dexamethasone-sparing regimen for glioblastoma: Spironolactone, ecallantide, clotrimazole. Neurochirurgie 67:5, pages 508-515.
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Richard E. Kast. (2021) Research Supporting a Pilot Study of Metronomic Dapsone during Glioblastoma Chemoirradiation. Medical Sciences 9:1, pages 12.
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Yuping Liu, Haiyan Xing, Xiangliang Jiang, Yan Chen, Mengmeng Huang & Suyun Yu. (2020) Network pharmacology-based preventive effect of XZF on cutaneous toxicities induced by EGFR inhibitor. Biomedicine & Pharmacotherapy 123, pages 109755.
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Mariarosaria Boccellino, Federica Pinto, Vincenzo Ieluzzi, Alfonso Giovane, Lucio Quagliuolo, Chiara Fariello, Mario Coppola, Annalisa Carlucci, Mario Santini, Kenan Ferati, Arbëresha Bexheti‐Ferati, Antonio Giordano & Marina Di Domenico. (2019) Proteomics analysis of human serum of patients with non‐small‐cell lung cancer reveals proteins as diagnostic biomarker candidates. Journal of Cellular Physiology 234:12, pages 23798-23806.
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Marina Di Domenico, Federica Pinto, Lucio Quagliuolo, Maria Contaldo, Giuliana Settembre, Antonio Romano, Mario Coppola, Kenan Ferati, Arbëresha Bexheti-Ferati, Antonella Sciarra, Giovanni Francesco Nicoletti, Giuseppe Andrea Ferraro & Mariarosaria Boccellino. (2019) The Role of Oxidative Stress and Hormones in Controlling Obesity. Frontiers in Endocrinology 10.
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Robert Ancuceanu, Mihaela Dinu, Florentina Furtunescu & Daniel Boda. (2019) An inventory of medicinal products causing skin rash: Clinical and regulatory lessons. Experimental and Therapeutic Medicine.
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Jing Du, Yuanqiao He, Weiquan Wu, Peng Li, Youwei Chen, Zhiming Hu & Yong Han. (2019) Targeting EphA2 with miR-124 mediates Erlotinib resistance in K-RAS mutated pancreatic cancer . Journal of Pharmacy and Pharmacology 71:2, pages 196-205.
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Richard Kast. (2018) Paths for Improving Bevacizumab Available in 2018: The ADZT Regimen for Better Glioblastoma Treatment. Medical Sciences 6:4, pages 84.
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Georg Karpel-Massler, Richard E. Kast, Markus D. Siegelin, Annika Dwucet, Elisabeth Schneider, Mike-Andrew Westhoff, Christian Rainer Wirtz, Xiao Yun Chen, Marc-Eric Halatsch & Carsten Bolm. (2017) Anti-glioma Activity of Dapsone and Its Enhancement by Synthetic Chemical Modification. Neurochemical Research 42:12, pages 3382-3389.
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Viswanath R. Belum, Michael A. Marchetti, Stephen W. Dusza, Andrea Cercek, Nancy E. Kemeny & Mario E. Lacouture. (2017) A prospective, randomized, double-blinded, split-face/chest study of prophylactic topical dapsone 5% gel versus moisturizer for the prevention of cetuximab-induced acneiform rash. Journal of the American Academy of Dermatology 77:3, pages 577-579.
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