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Current Medical Research and Opinion Volume 33, 2017 - Issue 11
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Pain

Pharmacokinetics and safety of fentanyl sublingual spray and fentanyl citrate intravenous: a single ascending dose study in opioid-naïve healthy volunteers

Richard RauckCarolinas Pain Institute, Winston Salem, NC, USA; Correspondence[email protected]
,
D. Alexander OhINSYS Development Company, Inc., Chandler, AZ, USA;
,
Neha ParikhINSYS Development Company, Inc., Chandler, AZ, USA;
,
Christian KochLotus Clinical Research LLC, Pasadena, CA, USA;
,
Neil SinglaLotus Clinical Research LLC, Pasadena, CA, USA;
,
Jin YuINSYS Development Company, Inc., Chandler, AZ, USA;
,
Srinivas NalamachuInternational Clinical Research Institute, Overland Park, KS, USA;
&
Santosh Vetticadenpreviously with INSYS Development Company, Inc., Chandler, AZ, USA
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Pages 1915-1920 | Received 15 May 2017, Accepted 05 Jul 2017, Published online: 11 Aug 2017

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Richard L. Rauck, D. Alexander Oh, Neil Singla, Christian Koch, Neha Parikh, Srinivas Nalamachu, Daniel Wilson, Jin Yu & Santosh Vetticaden. (2017) Pharmacokinetics and safety of fentanyl sublingual spray and fentanyl citrate intravenous: a multiple ascending dose study in opioid-naïve healthy volunteers. Current Medical Research and Opinion 33:11, pages 1921-1933.
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Articles from other publishers (4)

Sara Shum, Danny D. Shen & Nina Isoherranen. (2021) Predicting Maternal-Fetal Disposition of Fentanyl Following Intravenous and Epidural Administration Using Physiologically Based Pharmacokinetic Modeling. Drug Metabolism and Disposition 49:11, pages 1003-1015.
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Mari Fihlman, E. Karru, P. Varpe, H. Huhtinen, N. Hagelberg, T. I. Saari & K. T. Olkkola. (2020) Feasibility of a transmucosal sublingual fentanyl tablet as a procedural pain treatment in colonoscopy patients: a prospective placebo-controlled randomized study. Scientific Reports 10:1.
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Miriam Saiz‐Rodríguez, Dolores Ochoa, Coral Herrador, Carmen Belmonte, Manuel Román, Enrique Alday, Dora Koller, Pablo Zubiaur, Gina Mejía, María Hernández‐Martínez & Francisco Abad‐Santos. (2018) Polymorphisms associated with fentanyl pharmacokinetics, pharmacodynamics and adverse effects. Basic & Clinical Pharmacology & Toxicology 124:3, pages 321-329.
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Richard L. Rauck, D. Alexander Oh, Neil Singla, Christian Koch, Neha Parikh, Srinivas Nalamachu, Jin Yu & Steven James. (2018) Pharmacokinetics of Fentanyl Sublingual Spray in Opioid-Naïve Participants: Results of a Phase 1, Multiple Ascending Dose Study. Clinical Drug Investigation 38:8, pages 715-726.
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