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Current Medical Research and Opinion Volume 38, 2022 - Issue 2
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Pharmacology

What do we really know about the safety and efficacy of melatonin for sleep disorders?

David J. KennawayRobinson Research Institute and Adelaide School of Medicine, University of Adelaide, Adelaide, South Australia, AustraliaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-5864-3514
ORCID Icon
Pages 211-227 | Received 24 May 2021, Accepted 25 Oct 2021, Published online: 24 Nov 2021

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Julie Rolling, Juliette Rabot & Carmen M Schroder. (2022) Melatonin Treatment for Pediatric Patients with Insomnia: Is There a Place for It?. Nature and Science of Sleep 14, pages 1927-1944.
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Frank M. C. Besag & Michael J. Vasey. (2022) Adverse events in long-term studies of exogenous melatonin. Expert Opinion on Drug Safety 21:12, pages 1469-1481.
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Articles from other publishers (12)

Carol Paton, Paul Gringras, Alice Ruan, Ashley Liew, Olivia Rendora, Gaia Bove & Thomas R E Barnes. (2024) Quality of melatonin use in children and adolescents: findings from a UK clinical audit. BMJ Mental Health 27:1, pages e300894.
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Jean A. Boutin, Maxime Liberelle, Saïd Yous, Gilles Ferry & Françoise Nepveu. (2023) Melatonin facts: Lack of evidence that melatonin is a radical scavenger in living systems. Journal of Pineal Research 76:1.
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Jana Harenbrock, Heinz Holling, Graham Reid & Ivan Koychev. (2023) A meta-analysis of the relationship between sleep and β-Amyloid biomarkers in Alzheimer’s disease. Biomarkers in Neuropsychiatry 9, pages 100068.
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Mina Nicole Händel, Henning Keinke Andersen, Anja Ussing, Anne Virring, Poul Jennum, Nanette Mol Debes, Torben Laursen, Lone Baandrup, Christina Gade, Jette Dettmann, Jonas Holm, Camilla Krogh, Kirsten Birkefoss, Simon Tarp, Mette Bliddal & Henriette Edemann-Callesen. (2023) The short-term and long-term adverse effects of melatonin treatment in children and adolescents: a systematic review and GRADE assessment. eClinicalMedicine 61, pages 102083.
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Henriette Edemann-Callesen, Henning Keinke Andersen, Anja Ussing, Anne Virring, Poul Jennum, Nanette Mol Debes, Torben Laursen, Lone Baandrup, Christina Gade, Jette Dettmann, Jonas Holm, Camilla Krogh, Kirsten Birkefoss, Simon Tarp & Mina Nicole Händel. (2023) Use of melatonin in children and adolescents with idiopathic chronic insomnia: a systematic review, meta-analysis, and clinical recommendation. eClinicalMedicine 61, pages 102048.
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J. A. Boutin, D. J. Kennaway & R. Jockers. (2023) Melatonin: Facts, Extrapolations and Clinical Trials. Biomolecules 13:6, pages 943.
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David J Kennaway. (2023) The dim light melatonin onset across ages, methodologies, and sex and its relationship with morningness/eveningness. SLEEP 46:5.
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Deepa Burman, Karthikeyan Ramanujam, Dilshad Manzar, Vijay Kumar Chattu, David Warren Spence, Nevin F. W. Zaki, Haitham Jahrami & Seithikurippu R. Pandi-Perumal. (2023) Sleep and Autism Spectrum Disorder: A Comprehensive Review of Diagnosis, Markers, Interventions, and Treatments. Sleep and Vigilance 7:1, pages 9-22.
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Agnes Krause & Roland Seifert. 2023. Arzneiverordnungs-Report 2023. Arzneiverordnungs-Report 2023 579 588 .
Christine Salahub, Peter E. Wu, Lisa D. Burry, Christine Soong, Kathleen A. Sheehan, Thomas E. MacMillan & Lauren Lapointe-Shaw. (2022) Melatonin for Insomnia in Medical Inpatients: A Narrative Review. Journal of Clinical Medicine 12:1, pages 256.
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Mark J. Millan. (2022) Agomelatine for the treatment of generalized anxiety disorder: focus on its distinctive mechanism of action. Therapeutic Advances in Psychopharmacology 12, pages 204512532211051.
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Agnes Krause & Roland Seifert. 2022. Arzneiverordnungs-Report 2022. Arzneiverordnungs-Report 2022 543 552 .

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