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Connective Tissue Research Volume 61, 2020 - Issue 3-4: Ex Vivo Models of Musculoskeletal Tissues
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Original Articles

Mechanosensitive Ca2+ signaling and coordination is diminished in osteocytes of aged mice during ex vivo tibial loading

Andrea E. MorrellDepartment of Biomedical Engineering, Columbia University, New York, NY, USAView further author information
,
Samuel T. RobinsonDepartment of Biomedical Engineering, Columbia University, New York, NY, USAView further author information
,
Matthew J. SilvaDepartment of Orthopaedic Surgery, Musculoskeletal Research Center, Washington University, St. Louis, MO, USA;Department of Biomedical Engineering, Washington University, St. Louis, MO, USAView further author information
&
X. Edward GuoDepartment of Biomedical Engineering, Columbia University, New York, NY, USACorrespondence[email protected]
View further author information
Pages 389-398 | Received 28 Jun 2019, Accepted 03 Jan 2020, Published online: 13 Jan 2020

Citations (10)

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Spencer E. Szczesny. (2020) Ex vivo models of musculoskeletal tissues. Connective Tissue Research 61:3-4, pages 245-247.
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Articles from other publishers (9)

Xin Song, Amel Sassi, Kimberly Seaman, Chun-Yu Lin & Lidan You. (2023) Vibration Therapy for Cancer-Related Bone Diseases. Vibration 6:2, pages 449-465.
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Jiarui Cui, Yo Shibata, Tianmin Zhu, Jun Zhou & Jiaming Zhang. (2022) Osteocytes in bone aging: Advances, challenges, and future perspectives. Ageing Research Reviews 77, pages 101608.
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Joseph D. Gardinier, Amit Chougule & Chunbin Zhang. (2022) The mechanotransduction of MLO‐Y4 cells is disrupted by the senescence‐associated secretory phenotype of neighboring cells. Journal of Cellular Physiology 237:4, pages 2249-2257.
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Karl J. Lewis. (2021) Osteocyte calcium signaling – A potential translator of mechanical load to mechanobiology. Bone 153, pages 116136.
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Xiao Yang, Cong-Jin Liu, Zhen-Zhen Wang, Dong Ding, Jing-Wen Shi, Xin-Tong Wu, Lian-Wen Sun & Yu-Bo Fan. (2021) Effects of advanced glycation end products on osteocytes mechanosensitivity. Biochemical and Biophysical Research Communications 568, pages 151-157.
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Andrea E. Morrell, Samuel T. Robinson, Hua Zhu Ke, Gill Holdsworth & X. Edward Guo. (2021) Osteocyte mechanosensing following short-term and long-term treatment with sclerostin antibody. Bone 149, pages 115967.
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Apratim Bajpai, Rui Li & Weiqiang Chen. (2020) The cellular mechanobiology of aging: from biology to mechanics. Annals of the New York Academy of Sciences 1491:1, pages 3-24.
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E. E. A. Cramer, K. Ito & S. Hofmann. (2021) Ex vivo Bone Models and Their Potential in Preclinical Evaluation. Current Osteoporosis Reports 19:1, pages 75-87.
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Christopher J Chermside-Scabbo, Taylor L Harris, Michael D Brodt, Ingrid Braenne, Bo Zhang, Charles R Farber & Matthew J Silva. (2020) Old Mice Have Less Transcriptional Activation But Similar Periosteal Cell Proliferation Compared to Young-Adult Mice in Response to in vivo Mechanical Loading. Journal of Bone and Mineral Research 35:9, pages 1751-1764.
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