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Scandinavian Journal of Rheumatology Volume 35, 2006 - Issue 4
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The effect of methotrexate (MTX) on expression of signalling lymphocytic activation molecule (SLAM) in patients with rheumatoid arthritis (RA) and its role in the regulation of cytokine production

Y. Morita Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, TokyoCorrespondence[email protected]
,
T. Fukazawa Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, Tokyo
,
M. Hirashima Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, Tokyo
,
K. Kaga Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, Tokyo
,
M. Kusaoi Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, Tokyo
,
T. Morita Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, Tokyo
,
S. Touyama Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, Tokyo
,
K. Morita Morita Medical Clinic, SaitamaJapan
,
Y. Takasaki Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, Tokyo
&
H. Hashimoto Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, Tokyo
 show all
Pages 268-272 | Received 23 Mar 2005, Accepted 20 Jan 2006, Published online: 12 Jul 2009

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I. V. Shirinsky, O. I. Zheltova, N. Y. Solovyova, V. A. Kozlov & V. S. Shirinsky. (2009) Changes in disease activity, cytokine production, and proliferation of peripheral blood mononuclear cells in patients with rheumatoid arthritis after simvastatin treatment. Scandinavian Journal of Rheumatology 38:1, pages 23-27.
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C. P. Bramlage, C. Kaps, U. Ungethüm, P. Bramlage, M. Koziolek, J. Wessels, V. Krenn, A. Pruß, G. A. Müller, F. Strutz, G‐R. Burmester & T. Häupl. (2008) Modulatory effects of inflammation and therapy on GDF‐5 expression in rheumatoid arthritis synovium. Scandinavian Journal of Rheumatology 37:6, pages 401-409.
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H. P. Sennels, S. Sørensen, M. Østergaard, L. S. Knudsen, M. S. Hansen, H. Skjødt, N. D. Peters, A. Colic, K. Grau & S. Jacobsen. (2008) Circulating levels of osteopontin, osteoprotegerin, total soluble receptor activator of nuclear factor‐kappa B ligand, and high‐sensitivity C‐reactive protein in patients with active rheumatoid arthritis randomized to etanercept alone or in combination with methotrexate. Scandinavian Journal of Rheumatology 37:4, pages 241-247.
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W. H. Sommer, V. Ganiere, D. Gachoud, A. Keta, A. Abou‐Hajar, J. Dudler & D. Aujesky. (2008) Neurological and pulmonary adverse effects of subcutaneous methotrexate therapy. Scandinavian Journal of Rheumatology 37:4, pages 306-309.
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M‐C. Park, S‐J. Jung, Y‐B. Park & S‐K. Lee. (2008) Relationship of serum TWEAK level to cytokine level, disease activity, and response to anti‐TNF treatment in patients with rheumatoid arthritis. Scandinavian Journal of Rheumatology 37:3, pages 173-178.
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Articles from other publishers (9)

Yixin Zheng, Jianan Zhao, Mi Zhou, Kai Wei, Ping Jiang, Lingxia Xu, Cen Chang, Yu Shan, Linshuai Xu, Yiming Shi, Steven J. Schrodi, Shicheng Guo & Dongyi He. (2023) Role of signaling lymphocytic activation molecule family of receptors in the pathogenesis of rheumatoid arthritis: insights and application. Frontiers in Pharmacology 14.
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Jian Yang, Ya-rong Lin, Bo-jun Xiong, Ze-hong Chen, Yu-fei Luo, Ying Xu, Yan-ping Su, Hui-hui Huang & Chang-xi Yu. (2022) Regulation effect of koumine on T-helper cell polarization in rheumatoid arthritis. European Journal of Pharmacology 937, pages 175387.
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Afshin Ghavidel, Shirin Farivar, Shahin Aghamiri & Reza Shiari. (2022) Association between forkhead box P3 expression level and gender of Iranian juvenile idiopathic arthritis patients. Rheumatology 60:1, pages 26-34.
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Yevgeniya Gartshteyn, Anca D. Askanase & Adam Mor. (2021) SLAM Associated Protein Signaling in T Cells: Tilting the Balance Toward Autoimmunity. Frontiers in Immunology 12.
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Sabina Sandigursky, Mark R Philips & Adam Mor. (2020) SAP interacts with CD28 to inhibit PD-1 signaling in T lymphocytes. Clinical Immunology 217, pages 108485.
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Jonathan L. Marks & Christopher J. Edwards. (2012) Protective effect of methotrexate in patients with rheumatoid arthritis and cardiovascular comorbidity. Therapeutic Advances in Musculoskeletal Disease 4:3, pages 149-157.
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Song Xinqiang, Liang Fei, Liu Nan, Luo Yuan, Yuan Fang, Xue Hong, Tan Lixin, Long Juan, Zhao Xiao, Sun Yuying & Xi Yongzhi. (2010) Therapeutic efficacy of experimental rheumatoid arthritis with low-dose methotrexate by increasing partially CD4+CD25+Treg cells and inducing Th1 to Th2 shift in both cells and cytokines. Biomedicine & Pharmacotherapy 64:7, pages 463-471.
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Riejanne Seigers, Jessica Timmermans, Hans J. van der Horn, Erik F.J. de Vries, Rudi A. Dierckx, Lydia Visser, Sanne B. Schagen, Frits S.A.M. van Dam, Jaap M. Koolhaas & Bauke Buwalda. (2010) Methotrexate reduces hippocampal blood vessel density and activates microglia in rats but does not elevate central cytokine release. Behavioural Brain Research 207:2, pages 265-272.
Crossref
Jennie H. LawBonnie Koo & John Y.M. Koo. (2018) Methotrexate Update: Mechanism of Action in Psoriasis Therapy. Psoriasis Forum 14a:1, pages 17-28.
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