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Journal of Environmental Science and Health, Part B
Pesticides, Food Contaminants, and Agricultural Wastes
Volume 15, 1980 - Issue 6
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Original Articles

An overview of short‐term tests for the mutagenic and carcinogenic potential of pesticides

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Pages 867-906 | Published online: 21 Nov 2008

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Christopher Didigwu Nwani, Peace Onas Somdare, Emmanuel Okechukwu Ogueji, Jacinta Chinedu Nwani, Juliana Adimonye Ukonze & Alfreda O. Nwadinigwe. (2017) Genotoxicity assessment and oxidative stress responses in freshwater African catfish Clarias gariepinus exposed to fenthion formulations. Drug and Chemical Toxicology 40:3, pages 273-280.
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Gowri K. Uggini & Balakrishnan Suresh. (2013) Genotoxic effects of two different classes of insecticide in developing chick embryos. Toxicological & Environmental Chemistry 95:6, pages 992-1005.
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G. Prabhavathy Das, Abjal Pasha Shaik & Kaiser Jamil. (2006) Cytotoxicity and Genotoxicity Induced by the Pesticide Profenofos on Cultured Human Peripheral Blood Lymphocytes. Drug and Chemical Toxicology 29:3, pages 313-322.
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Kaiser Jamil, Abjal Pasha Shaik, M. Mahboob & D. Krishna. (2005) Effect of Organophosphorus and Organochlorine Pesticides (Monochrotophos, Chlorpyriphos, Dimethoate, and Endosulfan) on Human Lymphocytes In‐Vitro. Drug and Chemical Toxicology 27:2, pages 133-144.
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Michael C. R. Alavanja & Matthew R. Bonner. (2005) Pesticides and Human Cancers. Cancer Investigation 23:8, pages 700-711.
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J.S. Yadav & V.K. Kaushik. (2002) Studies on The Genotoxicity of An Organophosphorous Pesticide Baytex-1000. International Journal of Human Genetics 2:1, pages 19-25.
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M. Mahboob, M. F. Rahman, K. Danadevi, B. Saleha Banu & Paramjit Grover. (2002) DETECTION OF DNA DAMAGE IN MOUSE PERIPHERAL BLOOD LEUKOCYTES BY THE COMET ASSAY AFTER ORAL ADMINISTRATION OF MONOCROTOPHOS. Drug and Chemical Toxicology 25:1, pages 65-74.
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Tuula E. Tuormaa. (1995) Adverse Effects of Agrochemicals on Reproduction and Health: A Brief Review from the Literature. Journal of Nutritional & Environmental Medicine 5:4, pages 353-366.
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Antonia Velázquez, Noel Xamena, Amadeu Creus & Ricardo Marcos. (1990) Mutagenic evaluation of the organophosphorus insecticides methyl parathion and triazophos in drosophila melanogaster . Journal of Toxicology and Environmental Health 31:4, pages 313-325.
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KamalA. Rashid, NasriS. Kawar, LarryA. Hull & RalphO. Mumma. (1987) Residues and mutagenicity of captan applied to apple trees and potential human exposure. Journal of Environmental Science and Health, Part B 22:1, pages 71-89.
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KamalA. Rashid & RalphO. Mumma. (1984) Genotoxicity of methyl parathion in short‐term bacterial test systems. Journal of Environmental Science and Health, Part B 19:6, pages 565-577.
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Yin‐Tak Woo. (1983) Carcinogenicity, mutagenicity and teratogenicity of carbamates, thio‐carbamates and related compounds: An overview of structure‐activity relationships and environmental concerns . Journal of Environmental Science and Health. Part C: Environmental Carcinogenesis Reviews 1:1, pages 97-133.
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Articles from other publishers (65)

Michael K. Peterson. 2003. Patty's Toxicology. Patty's Toxicology 1 186 .
Shilpa Olakkaran, Anupama Kizhakke Purayil, Anet Antony, Shanthala Mallikarjunaiah & Gurushankara Hunasanahally Puttaswamygowda. (2020) Oxidative stress-mediated genotoxicity of malathion in human lymphocytes. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 849, pages 503138.
Crossref
Suprakas Sinha Ray, Rashi Gusain & Neeraj Kumar. 2020. Carbon Nanomaterial-Based Adsorbents for Water Purification. Carbon Nanomaterial-Based Adsorbents for Water Purification 1 9 .
B. Reddi Bhargavi, Ravi Kumar VELLANKI & Jagadeeswara Kanala Reddy. (2019) EVALUATION OF CERTAIN PESTICIDE MIXTURES FOR THEIR MUTAGENICITY USING AMES Salmonella typhimurium - REVERSE MUTATION ASSAY. Journal of Experimental Biology and Agricultural Sciences 7:6, pages 606-612.
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. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 41 .
Abhay Singh Yadav, Anita Bhatnagar & Manjeet Kaur. (2010) Assessment of Genotoxic Effects of Butachlor in Fresh Water Fish, Cirrhinus mrigala (Hamilton). Research Journal of Environmental Toxicology 4:4, pages 223-230.
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Emanuela Testai, Franca M. Buratti & Emma Di Consiglio. 2010. Hayes' Handbook of Pesticide Toxicology. Hayes' Handbook of Pesticide Toxicology 1505 1526 .
J. Venkateswara Rao, S.K. Arepalli, V.G. Gunda & J. Bharat Kumar. (2008) Assessment of cytoskeletal damage in Paramecium caudatum: An early warning system for apoptotic studies. Pesticide Biochemistry and Physiology 91:2, pages 75-80.
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Won Jin Lee, Dale P. Sandler, Aaron Blair, Claudine Samanic, Amanda J. Cross & Michael C.R. Alavanja. (2007) Pesticide use and colorectal cancer risk in the agricultural health study. International Journal of Cancer 121:2, pages 339-346.
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Nada H.A. Al-Twaty .. (2006) Mutagenic Effects of Ethephon on Albino Mice. Journal of Biological Sciences 6:6, pages 1041-1046.
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Kara C. Sorensen, Joseph W. Stucki, Richard E. Warner, Elizabeth D. Wagner & Michael J. Plewa. (2005) Modulation of the genotoxicity of pesticides reacted with redox‐modified smectite clay. Environmental and Molecular Mutagenesis 46:3, pages 174-181.
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W. J. Lee, A. Blair, J. A. Hoppin, J. H. Lubin, J. A. Rusiecki, D. P. Sandler, M. Dosemeci & M. C. R. Alavanja. (2004) Cancer Incidence Among Pesticide Applicators Exposed to Chlorpyrifos in the Agricultural Health Study. JNCI Journal of the National Cancer Institute 96:23, pages 1781-1789.
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Takeshi Ohe, Tetsushi Watanabe & Keiji Wakabayashi. (2004) Mutagens in surface waters: a review. Mutation Research/Reviews in Mutation Research 567:2-3, pages 109-149.
Crossref
. 2004. Sax's Dangerous Properties of Industrial Materials. Sax's Dangerous Properties of Industrial Materials.
. 2004. Sax's Dangerous Properties of Industrial Materials. Sax's Dangerous Properties of Industrial Materials.
. 2004. Sax's Dangerous Properties of Industrial Materials. Sax's Dangerous Properties of Industrial Materials.
. 2004. Sax's Dangerous Properties of Industrial Materials. Sax's Dangerous Properties of Industrial Materials.
Y Tian & T Yamauchi. (2003) Micronucleus formation in 3-day mouse embryos associated with maternal exposure to chlorpyrifos during the early preimplantation period. Reproductive Toxicology 17:4, pages 401-405.
Crossref
Henry J. Trochimowicz, Gerald L. KennedyJr.Jr. & Neil D. Krivanek. 2003. Patty's Toxicology. Patty's Toxicology.
Elke Kennepohl & Ian C. Munro. 2001. Handbook of Pesticide Toxicology. Handbook of Pesticide Toxicology 1623 1638 .
Patrizia Hrelia. 1997. Advances in Environmental Control Technology: Health and Toxicology. Advances in Environmental Control Technology: Health and Toxicology 415 432 .
Sebastian Kevekordes, Thomas Gebel, Katharina Pav, Rudolf Edenharder & Hartmut Dunkelberg. (1996) Genotoxicity of selected pesticides in the mouse bone-marrow micronucleus test and in the sister-chromatid exchange test with human lymphocytes in vitro. Toxicology Letters 89:1, pages 35-42.
Crossref
Zehra Rehana, Abdul Malik & Masood Ahmad. (1996) Genotoxicity of the Ganges water at Narora (U.P.), India. Mutation Research/Genetic Toxicology 367:4, pages 187-193.
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Carrie Taets. (1996) The Effects of Herbicide Interaction on Chinese Hamster Ovary Cells. Journal of Natural Resources and Life Sciences Education 25:1, pages 81-84.
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Zehra Rehana, Abdul Malik & Masood Ahmad. (1995) Mutagenic activity of the ganges water with special reference to the pesticide pollution in the river between Kachla to Kannauj (U.P.), India. Mutation Research/Genetic Toxicology 343:2-3, pages 137-144.
Crossref
Patrizia Hrelia, Fernanda Vigagni, Francesca Maffei, Marta Morotti, Annamaria Colacci, Paolo Perocco, Sandro Grilli & Giorgio Cantelli-Forti. (1994) Genetic safety evaluation of pesticides in different short-term tests. Mutation Research/Genetic Toxicology 321:4, pages 219-228.
Crossref
L. Bianchi, A. Zannoli, R. Pizzala, L.A. Stivala & E. Chiesara. (1994) Genotoxicity assay of five pesticides and their mixtures in Saccharomyces cerevisiae D7. Mutation Research/Genetic Toxicology 321:4, pages 203-211.
Crossref
J.M. Safi, Y.Z. El-Nahhal, S.A. Soliman & A.H. El-Sebae. (1993) Mutagenic and carcinogenic pesticides used in the agricultural environment of Gaza Strip. Science of The Total Environment 132:2-3, pages 371-380.
Crossref
Ian C. Munro, George L. Carlo, Joan C. Orr, Kelly G. Sund, Ross M. Wilson, Elke Kennepohl, Barry S. Lynch & Maureen Jablinske. (2016) A Comprehensive, Integrated Review and Evaluation of the Scientific Evidence Relating to the Safety of the Herbicide 2,4-D. Journal of the American College of Toxicology 11:5, pages 559-664.
Crossref
Soheir M. Amer & Fawzia A.E. Aly. (1992) Cytogenetic effects of pesticides. IV. Cytogenetic effects of the insecticides Gardona and Dursban. Mutation Research/Genetic Toxicology 279:3, pages 165-170.
Crossref
Ronald D. Snyder. (2006) Effects of captan on dna and dna metabolic processes in human diploid fibroblasts. Environmental and Molecular Mutagenesis 20:2, pages 127-133.
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M. V. Usha Rani & M. Sanjeeva Rao. (1991) In vitro effect of fenthion on human lymphocytes. Bulletin of Environmental Contamination and Toxicology 47:2, pages 316-320.
Crossref
M.K.J. Siddiqui, M. Mahboob & M. Mustafa. (1990) Hepatic and extra hepatic glutathione depletion and glutathione-S-transferase inhibition by monocrotophos and its two thiol analogues. Toxicology 64:3, pages 271-279.
Crossref
Mohammed A. Q. Khan. 1990. Controlled Release, Biochemical Effects of Pesticides, Inhibition of Plant Pathogenic Fungi. Controlled Release, Biochemical Effects of Pesticides, Inhibition of Plant Pathogenic Fungi 109 171 .
P. Perocco, G. Ancora, P. Rani, A. M. Valenti, M. Mazzullo, A. Colacci & S. Grilli. (2008) Evaluation of genotoxic effects of the herbicide dicamba using in vivo and in vitro test systems. Environmental and Molecular Mutagenesis 15:3, pages 131-135.
Crossref
N. K. Tripathy, L. Dey, B. Majhi & C. C. Das. (1987) Genotoxicity of metacid established through the somatic and germ line mosaic assays and the sex-linked recessive lethal test in drosophila. Archives of Toxicology 61:1, pages 53-57.
Crossref
P.K. Malhi & I.S. Grover. (1987) Genotoxic effects of some organophosphorus pesticides II. In vivo chromosomal aberration bioassay in bone marrow cells in rat. Mutation Research/Genetic Toxicology 188:1, pages 45-51.
Crossref
Peter Chidiac & Mark T. Goldberg. (2006) Lack of induction of nuclear aberrations by captan in mouse duodenum. Environmental Mutagenesis 9:3, pages 297-306.
Crossref
A. Velázquez, N. Xamena, A. Creus & R. Marcos. (1986) Indication for weak mutagenicity of the organophosphorus insecticide dimethoate in Drosophila melanogaster. Mutation Research/Genetic Toxicology 172:3, pages 237-243.
Crossref
Gilles Klopman, Renato Contreras, Herbert S. Rosenkranz & Michael D. Waters. (1985) Structure-genotoxic activity relationships of pesticides: comparison of the results from several short-term assays. Mutation Research/Environmental Mutagenesis and Related Subjects 147:6, pages 343-356.
Crossref
J.H. Carver, J. Bootman, M.C. Cimino, H.J. Esber, P. Kirby, B. Kirkhart, Z.A. Wong & J.A. MacGregor. (1985) Genotoxic potential of acephate technical: In vitro and in vivo effects. Toxicology 35:2, pages 125-142.
Crossref
I.S. Grover & P.K. Malhi. (1985) Genotoxic effects of some organophosphorous pesticides I. Induction of micronuclei in bone marrow cells in rat. Mutation Research/Genetic Toxicology 155:3, pages 131-134.
Crossref
YIN-TAK WOO, DAVID Y. LAI, JOSEPH C. ARCOS & MARY F. ARGUS. 1985. Aliphatic and Polyhalogenated Carcinogens. Aliphatic and Polyhalogenated Carcinogens 3 414 .
Friederike Eckardt & R. C. von Borstel. 1985. Basic and Applied Mutagenesis. Basic and Applied Mutagenesis 221 248 .
Shahbeg S. Sandhu, Michael D. Waters, Vincent F. Simmon, Kristien E. Mortelmans, Ann D. Mitchell, Ted Jorgenson, David C. L. Jones, Ruby Valencia & Frank Stack. 1985. Basic and Applied Mutagenesis. Basic and Applied Mutagenesis 185 219 .
A. H. El-Sebae. 1985. Appropriate Waste Management for Developing Countries. Appropriate Waste Management for Developing Countries 563 577 .
Gabriele Aquilina, Romualdo Benigni, Margherita Bignami, Angelo Calcagnile, Eugenia Dogliotti, Emiliana Falcone & Angelo Carere. (2006) Genotoxic activity of dichlorvos, trichlorfon and dichloroacetaldehyde. Pesticide Science 15:5, pages 439-442.
Crossref
Roman J. Pienta, Lawrence M. Kushner & L.Sue Russell. (1984) The use of short-term tests and limited bioassays in carcinogenicity testing. Regulatory Toxicology and Pharmacology 4:3, pages 249-260.
Crossref
S. Singh, B. Lehmann-Grube & H. W. Goedde. (1984) Cytogenetic effects of paraoxon and methyl-parathion on cultured human lymphocytes: SCE, clastogenic activity and cell cycle delay. International Archives of Occupational and Environmental Health 54:3, pages 195-200.
Crossref
June H. Carver, Judith A. Macgregor & R. W. King. (2006) Mutagenicity and chemical characterization of two petroleum distillates. Journal of Applied Toxicology 4:4, pages 163-169.
Crossref
THOMAS R. BARFKNECHT & ROBERT W. NAISMITH. (1984) Methodology for Evaluating the Genotoxicity of Hazardous Environmental Samples. Hazardous Waste 1:1, pages 93-109.
Crossref
Harold C. Grice. 1984. Interpretation and Extrapolation of Chemical and Biological Carcinogenicity Data to Establish Human Safety Standards. Interpretation and Extrapolation of Chemical and Biological Carcinogenicity Data to Establish Human Safety Standards 153 197 .
Ghislaine Grutman, Louis Schoofs, Jean-François Lontie & Nik Larebeke. 1984. Residue Reviews. Residue Reviews 1 46 .
N.V. Vigfusson, E.R. Vyse, C.A. Pernsteiner & R.J. Dawson. (1983) In vivo induction of sister-chromatid exchange in Umbra limi by the insecticides endrin, chlordane, diazinon and guthion. Mutation Research/Genetic Toxicology 118:1-2, pages 61-68.
Crossref
R. C. Sobti, A. Krishan & J. Davies. (1983) Cytokinetic and cytogenetic effect of agricultural chemicals on human lymphoid cells in vitro. Archives of Toxicology 52:3, pages 221-231.
Crossref
R.C. Sobti, A. Krishan & C.D. Pfaffenberger. (1982) Cytokinetic and cytogenetic effects of some agricultural chemicals on human lymphoid cells in vitro: organophosphates. Mutation Research/Genetic Toxicology 102:1, pages 89-102.
Crossref
James M. Gentile, Glenda J. Gentile, Judy Bultman, Robert Sechriest, Elizabeth D. Wagner & Michael J. Plewa. (1982) An evaluation of the genotoxic properties of insecticides following plant and animal activation. Mutation Research/Genetic Toxicology 101:1, pages 19-29.
Crossref
Michael D. Waters, Shahbeg S. Sandhu, Vincent F. Simmon, Kristien E. Mortelmans, Ann D. Mitchell, Ted A. Jorgenson, David C. L. Jones, Ruby Valencia & Neil E. Garrett. 1982. Genetic Toxicology. Genetic Toxicology 275 326 .
A. H. El-Sebae & S. A. Soliman. 1982. Genetic Toxicology. Genetic Toxicology 119 126 .
H.H. Chen, J.L. Hsueh, S.R. Sirianni & C.C. Huang. (1981) Induction of sister-chromatid exchanges and cell cycle delay in cultured mammalian cells treated with eight organophosphorus pesticides. Mutation Research/Genetic Toxicology 88:3, pages 307-316.
Crossref
Shahbeg Sandhu. 1980. Short-Term Bioassays in the Analysis of Complex Environmental Mixtures II. Short-Term Bioassays in the Analysis of Complex Environmental Mixtures II 203 210 .

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