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Research Article

Arylamine N-Acetyltransferases: What We Learn from Genes and Genomes

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Pages 511-564 | Published online: 09 Oct 2008

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Read on this site (16)

Stephen C. Mitchell. (2020) N-acetyltransferase: the practical consequences of polymorphic activity in man. Xenobiotica 50:1, pages 77-91.
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Jolantha Beyerle, Eva Frei, Marie Stiborova, Nina Habermann & Cornelia M. Ulrich. (2015) Biotransformation of xenobiotics in the human colon and rectum and its association with colorectal cancer. Drug Metabolism Reviews 47:2, pages 199-221.
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Hae-Jeung Lee, Kana Wu, DavidG. Cox, David Hunter, SusanE. Hankinson, WalterC. Willett, Rashmi Sinha & Eunyoung Cho. (2013) Polymorphisms in Xenobiotic Metabolizing Genes, Intakes of Heterocyclic Amines and Red Meat, and Postmenopausal Breast Cancer. Nutrition and Cancer 65:8, pages 1122-1131.
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Holly M Mortensen, Alain Froment, Godfrey Lema, Jean-Marie Bodo, Muntaser Ibrahim, Thomas B Nyambo, Sabah A Omar & Sarah A Tishkoff. (2011) Characterization of Genetic Variation and Natural Selection at the Arylamine N-Acetyltransferase Genes in Global Human Populations. Pharmacogenomics 12:11, pages 1545-1558.
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Malika Khelil, Bahia Djerdjouri & Bouchentouf Tayebi. (2010) N-acetyltransferase 2 (Nat2) polymorphism in the sand rat Psammomys obesus. Toxicology Mechanisms and Methods 20:8, pages 440-444.
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Nilüfer Rahmioğlu & Kourosh R Ahmadi. (2010) Classical Twin Design in Modern Pharmacogenomics Studies. Pharmacogenomics 11:2, pages 215-226.
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Katy Walker, Gary Ginsberg, Dale Hattis, Douglas O. Johns, Kathryn Z. Guyton & Babasaheb Sonawane. (2009) Genetic Polymorphism in N-Acetyltransferase (NAT): Population Distribution of NAT1 and NAT2 Activity. Journal of Toxicology and Environmental Health, Part B 12:5-6, pages 440-472.
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Margherita Strolin Benedetti, Rhys Whomsley, Italo Poggesi, Willi Cawello, François-Xavier Mathy, Marie-Laure Delporte, Peggy Papeleu & Jean-Baptiste Watelet. (2009) Drug metabolism and pharmacokinetics. Drug Metabolism Reviews 41:3, pages 344-390.
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David W Hein. (2009) N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine. Expert Opinion on Drug Metabolism & Toxicology 5:4, pages 353-366.
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Lesley A Stanley & Edith Sim. (2008) Update on the Pharmacogenetics of NATs: Structural Considerations. Pharmacogenomics 9:11, pages 1673-1693.
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Sotiria Boukouvala, Isaac M Westwood, Neville J Butcher & Giannoulis Fakis. (2008) Current Trends in N-Acetyltransferase Research Arising from the 2007 International NAT Workshop. Pharmacogenomics 9:6, pages 765-771.
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Larissa Wakefield, Valerie Cornish, Hilary Long, Akane Kawamura, Xiaoyan Zhang, David W. Hein & Edith Sim. (2008) Mouse arylamine N-acetyltransferase 2 (Nat2) expression during embryogenesis: a potential marker for the developing neuroendocrine system. Biomarkers 13:1, pages 106-118.
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Edith Sim, Kylie Walters & Sotiria Boukouvala. (2008) Arylamine N-acetyltransferases: From Structure to Function. Drug Metabolism Reviews 40:3, pages 479-510.
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Jason M. Walraven, John O. Trent & David W. Hein. (2008) Structure-Function Analyses of Single Nucleotide Polymorphisms in Human N-Acetyltransferase 1. Drug Metabolism Reviews 40:1, pages 169-184.
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Edith Sim, Isaac Westwood & Elizabeth Fullam. (2007) Arylamine N-acetyltransferases. Expert Opinion on Drug Metabolism & Toxicology 3:2, pages 169-184.
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