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Research Article

Human Cytochrome P450 Family 4 Enzymes: Function, Genetic Variation and Regulation

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Pages 515-538 | Published online: 09 Oct 2008

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Atsunori Miyata, Masatoshi Hasegawa, Kenji Hachiuma, Haruyuki Mori, Nobuko Horiuchi, Akiko Mizuno-Yasuhira, Yukihiro Chino, Shigeji Jingu, Soichi Sakai, Yoshishige Samukawa, Yasuhiro Nakai & Jun-ichi Yamaguchi. (2017) Metabolite profiling and enzyme reaction phenotyping of luseogliflozin, a sodium–glucose cotransporter 2 inhibitor, in humans. Xenobiotica 47:4, pages 332-345.
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Giuseppe Lo Sasso, Bjoern Titz, Catherine Nury, Stéphanie Boué, Blaine Phillips, Vincenzo Belcastro, Thomas Schneider, Sophie Dijon, Karine Baumer, Daruisz Peric, Remi Dulize, Ashraf Elamin, Emmanuel Guedj, Ansgar Buettner, Patrice Leroy, Samuel Kleinhans, Gregory Vuillaume, Emilija Veljkovic, Nikolai V. Ivanov, Florian Martin, Patrick Vanscheeuwijck, Manuel C. Peitsch & Julia Hoeng. (2016) Effects of cigarette smoke, cessation and switching to a candidate modified risk tobacco product on the liver in Apoe−/− mice – a systems toxicology analysis. Inhalation Toxicology 28:5, pages 226-240.
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Shotaro Uehara, Norie Murayama, Yasuharu Nakanishi, Chika Nakamura, Takanori Hashizume, Darryl C. Zeldin, Hiroshi Yamazaki & Yasuhiro Uno. (2015) Immunochemical quantification of cynomolgus CYP2J2, CYP4A and CYP4F enzymes in liver and small intestine. Xenobiotica 45:2, pages 124-130.
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Mariko Nakano, Catherine M. Lockhart, Edward J. Kelly & Allan E. Rettie. (2014) Ocular cytochrome P450s and transporters: roles in disease and endobiotic and xenobiotic disposition. Drug Metabolism Reviews 46:3, pages 247-260.
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Youcai Zhang & Curtis D. Klaassen. (2013) Hormonal regulation of Cyp4a isoforms in mouse liver and kidney. Xenobiotica 43:12, pages 1055-1063.
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Shakil Ahmed Saghir, Sarosh Ahmed Khan & Alene Theresa McCoy. (2012) Ontogeny of mammalian metabolizing enzymes in humans and animals used in toxicological studies. Critical Reviews in Toxicology 42:5, pages 323-357.
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Kirsty J. McLean & Andrew W. Munro. (2008) Structural Biology and Biochemistry of Cytochrome P450 Systems in Mycobacterium tuberculosis. Drug Metabolism Reviews 40:3, pages 427-446.
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