Citations (148)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (17)
Cristina Villanueva-Bueno, Vicente Escudero-Vilaplana, Roberto Collado-Borrell, Álvaro Giménez-Manzorro, Almudena Ribed, Belén Marzal-Alfaro, José Luis Revuelta-Herrero, Eva Gonzalez-Haba, Ana Herranz & Maria Sanjurjo. (2022) Medication guide for the perioperative management of oral antineoplastic agents in cancer patients. Expert Opinion on Drug Safety 21:1, pages 107-119.
Read now
Read now
Junmei Chen, Jinman Liu, Yueyue Huang, Ruoyu Li, Cuiru Ma, Beiping Zhang, Fanchang Wu, Wenqian Yu, Xue Zuo, Yong Liang & Qi Wang. (2021) Insights into oral bioavailability enhancement of therapeutic herbal constituents by cytochrome P450 3A inhibition. Drug Metabolism Reviews 53:4, pages 491-507.
Read now
Read now
Alexandra L Degraeve, Serge Moudio, Vincent Haufroid, Djamila Chaib Eddour, Michel Mourad, Laure B Bindels & Laure Elens. (2020) Predictors of tacrolimus pharmacokinetic variability: current evidences and future perspectives. Expert Opinion on Drug Metabolism & Toxicology 16:9, pages 769-782.
Read now
Read now
Davide Seripa, Madia Lozupone, Eleonora Stella, Giulia Paroni, Paola Bisceglia, Maddalena La Montagna, Grazia D’onofrio, Carolina Gravina, Maria Urbano, Maria Giovanna Priore, Angela Lamanna, Antonio Daniele, Antonello Bellomo, Giancarlo Logroscino, Antonio Greco & Francesco Panza. (2017) Psychotropic drugs and CYP2D6 in late-life psychiatric and neurological disorders. What do we know?. Expert Opinion on Drug Safety 16:12, pages 1373-1385.
Read now
Read now
Ping Fang, Peng-fei Tang, Ren-ai Xu, Xiang Zheng, Jian Wen, Su-su Bao, Jian-ping Cai & Guo-xin Hu. (2017) Functional assessment of CYP3A4 allelic variants on lidocaine metabolism in vitro. Drug Design, Development and Therapy 11, pages 3503-3510.
Read now
Read now
Liang Yan, Jingyang Liu, Yunlong Zhao, Yali Nie, Xiaochao Ma, Quancheng Kan & Lirong Zhang. (2017) Suppression of miR-628-3p and miR-641 is Involved in Rifampin-Mediated CYP3A4 Induction in HepaRG Cells. Pharmacogenomics 18:1, pages 57-64.
Read now
Read now
J.T. Tang, L.M. Andrews, T. van Gelder, Y.Y. Shi, R.H.N. van Schaik, L.L. Wang & D.A. Hesselink. (2016) Pharmacogenetic aspects of the use of tacrolimus in renal transplantation: recent developments and ethnic considerations. Expert Opinion on Drug Metabolism & Toxicology 12:5, pages 555-565.
Read now
Read now
Almudena Ribed, Vicente Escudero-Vilaplana, Rosa Maria Romero-Jimenez, Irene Iglesias-Peinado, Ana Herranz-Alonso & Maria Sanjurjo-Saez. (2016) Guiding pharmacist clinical interviews: a safety tool to support the education of patients treated with oral antineoplastic agents. Expert Opinion on Drug Safety 15:4, pages 427-435.
Read now
Read now
Maria Konstandi. (2013) Psychophysiological stress: a significant parameter in drug pharmacokinetics. Expert Opinion on Drug Metabolism & Toxicology 9:10, pages 1317-1334.
Read now
Read now
Wanda Baer-Dubowska & Hanna Szaefer. (2013) Modulation of carcinogen-metabolizing cytochromes P450 by phytochemicals in humans. Expert Opinion on Drug Metabolism & Toxicology 9:8, pages 927-941.
Read now
Read now
Marilyn N. Martinez, Leposava Antonovic, Michael Court, Mauro Dacasto, Johanna Fink-Gremmels, Butch Kukanich, Chuck Locuson, Katrina Mealey, Michael J. Myers & Lauren Trepanier. (2013) Challenges in exploring the cytochrome P450 system as a source of variation in canine drug pharmacokinetics. Drug Metabolism Reviews 45:2, pages 218-230.
Read now
Read now
Stefanie D Krens, Howard L McLeod & Daniel L Hertz. (2013) Pharmacogenetics, Enzyme Probes and Therapeutic drug Monitoring as Potential Tools for Individualizing Taxane Therapy. Pharmacogenomics 14:5, pages 555-574.
Read now
Read now
Murielle Bochud & Idris Guessous. (2012) Gene–environment interactions of selected pharmacogenes in arterial hypertension. Expert Review of Clinical Pharmacology 5:6, pages 677-686.
Read now
Read now
Joseph McGraw & Donald Waller. (2012) Cytochrome P450 variations in different ethnic populations. Expert Opinion on Drug Metabolism & Toxicology 8:3, pages 371-382.
Read now
Read now
Bao Ting Zhu. (2010) On the general mechanism of selective induction of cytochrome P450 enzymes by chemicals: some theoretical considerations. Expert Opinion on Drug Metabolism & Toxicology 6:4, pages 483-494.
Read now
Read now
Murielle Bochud, Pascal Bovet, Michel Burnier & Chin B Eap. (2009)
CYP3A5 and ABCB1 Genes and Hypertension. Pharmacogenomics 10:3, pages 477-487.
Read now
Read now
K. L. Mealey, M. Jabbes, E. Spencer & J. M. Akey. (2008) Differential expression of and mRNAs in canine liver and intestine. Xenobiotica 38:10, pages 1305-1312.
Read now
Read now
Articles from other publishers (131)
Cuitong Wang, Bin Cheng, Wei Wei, Lanlan Gui, Wushuang Zeng, Yutong Wang, Yixuan Wang, Qi Chen, Liang Xu, Jia Miao & Ke Lan. (2024) Comparison of 1Beta- and 5Beta-hydroxylation of Deoxycholate and Glycodeoxycholate as In Vitro Index Reactions for Cytochrome P450 3A Activities. Drug Metabolism and Disposition 52:2, pages 126-134.
Crossref
Crossref
Cui Li, Xiaokun Li, Ali Fan, Ning He, Dongmei Wu, Hongyan Yu, Kun Wang, Weijie Jiao & Xu Zhao. (2024) Evidence for cytochrome P450 3A4‐mediated metabolic activation of SCO‐267. Biopharmaceutics & Drug Disposition 45:1, pages 30-42.
Crossref
Crossref
Jinjuta Ngeyvijit, Sopita Nuansuwan & Vorakamol Phoophiboon. (2023) CYP3A4/P-glycoprotein inhibitors related colchicine toxicity mimicking septic shock. BMJ Case Reports 16:10, pages e257186.
Crossref
Crossref
Fei Teng, Zhongwen Lu, Fei Gao, Jing Liang, Jiawen Li, Xuanhe Tian, Xianshuai Wang, Haowei Guan & Jin Wang. (2023) Systems biology approaches to identify potential targets and inhibitors of the intestinal microbiota to treat depression. Scientific Reports 13:1.
Crossref
Crossref
Andres Delgado & Steven Enkemann. (2023) Three Layers of Personalized Medicine in the Use of Sirolimus and Its Derivatives for the Treatment of Cancer. Journal of Personalized Medicine 13:5, pages 745.
Crossref
Crossref
Piotr Stępnicki, Katarzyna M. Targowska-Duda, Antón L. Martínez, Agata Zięba, Olga Wronikowska-Denysiuk, Martyna Z. Wróbel, Agata Bartyzel, Alicja Trzpil, Tomasz M. Wróbel, Andrzej Chodkowski, Karolina Mirecka, Tadeusz Karcz, Katarzyna Szczepańska, Maria I. Loza, Barbara Budzyńska, Jadwiga Turło, Jadwiga Handzlik, Emilia Fornal, Ewa Poleszak, Marián Castro & Agnieszka A. Kaczor. (2023) Discovery of novel arylpiperazine-based DA/5-HT modulators as potential antipsychotic agents – Design, synthesis, structural studies and pharmacological profiling. European Journal of Medicinal Chemistry 252, pages 115285.
Crossref
Crossref
Lu-Ning Sun, Ye Shen, Yu-Qing Yang, Xiang-Long Chen, Feng-Ru Huang, Dun-Jian Wang, Ye Zhang, Da-Wei Wang & Yong-Qing Wang. (2023) Simultaneous Determination of Cortisol and 6β-Hydroxycortisol in Human Plasma by Liquid Chromatography–Tandem Mass Spectrometry. Journal of Chromatographic Science 61:2, pages 130-139.
Crossref
Crossref
永敏 刘. (2023) Research Progress of CYP450 Substrates, Inhibitors, Inducers and Species Specificity. Pharmacy Information 12:02, pages 70-80.
Crossref
Crossref
Krupa A. Patel, Masumi H. Bhatt, Rajvi V. Hirani, Vidheesha A. Patel, Vishvas N. Patel, Gaurang B. Shah & Mehul R. Chorawala. (2022) Assessment of potential drug–drug interactions among outpatients in a tertiary care hospital: focusing on the role of P-glycoprotein and CYP3A4 (retrospective observational study). Heliyon 8:11, pages e11278.
Crossref
Crossref
Lyubov S. Klyushova, Maria L. Perepechaeva & Alevtina Y. Grishanova. (2022) The Role of CYP3A in Health and Disease. Biomedicines 10:11, pages 2686.
Crossref
Crossref
Joshua J. Goings, Alec White, Joonho Lee, Christofer S. Tautermann, Matthias Degroote, Craig Gidney, Toru Shiozaki, Ryan Babbush & Nicholas C. Rubin. (2022) Reliably assessing the electronic structure of cytochrome P450 on today’s classical computers and tomorrow’s quantum computers. Proceedings of the National Academy of Sciences 119:38.
Crossref
Crossref
QingLiang Wu, YiTing Hu, CuiTong Wang, Wei Wei, LanLan Gui, WuShuang Zeng, Changxiao Liu, Wei Jia, Jia Miao & Ke Lan. (2022) Reevaluate In Vitro CYP3A Index Reactions of Benzodiazepines and Steroids between Humans and Dogs. Drug Metabolism and Disposition 50:6, pages 741-749.
Crossref
Crossref
Zeenat A. Shyr, Yu-Shan Cheng & Wei Zheng. 2022. Comprehensive Pharmacology. Comprehensive Pharmacology
789
812
.
Tomas Smutny, Veronika Bernhauerova, Lucie Smutna, Jurjen Duintjer Tebbens & Petr Pavek. (2021) Expression dynamics of pregnane X receptor-controlled genes in 3D primary human hepatocyte spheroids. Archives of Toxicology 96:1, pages 195-210.
Crossref
Crossref
Grace M. McBride, Ashley S. Meakin, Jia Yin Soo, Jack R.T. Darby, Tamara J. Varcoe, Emma L. Bradshaw, Mitchell C. Lock, Stacey L. Holman, Brahmdeep S. Saini, Christopher K. Macgowan, Mike Seed, Mary J. Berry, Michael D. Wiese & Janna L. Morrison. (2021) Intrauterine growth restriction alters the activity of drug metabolising enzymes in the maternal-placental-fetal unit. Life Sciences 285, pages 120016.
Crossref
Crossref
Yitong Liu, Mapa S. T. Mapa & Robert L. Sprando. (2021) Anthraquinones inhibit cytochromes P450 enzyme activity in silico and in vitro. Journal of Applied Toxicology 41:9, pages 1438-1445.
Crossref
Crossref
Jun Liang, Jason R. Zbieg, Robert A. Blake, Jae H. Chang, Stephen Daly, Antonio G. DiPasquale, Lori S. Friedman, Thomas Gelzleichter, Matthew Gill, Jennifer M. Giltnane, Simon Goodacre, Jane Guan, Steven J. Hartman, Ellen Rei Ingalla, Lorn Kategaya, James R. Kiefer, Tracy Kleinheinz, Sharada S. Labadie, Tommy Lai, Jun Li, Jiangpeng Liao, Zhiguo Liu, Vidhi Mody, Neville McLean, Ciara Metcalfe, Michelle A. Nannini, Jason Oeh, Martin G. O’Rourke, Daniel F. Ortwine, Yingqing Ran, Nicholas C. Ray, Fabien Roussel, Amy Sambrone, Deepak Sampath, Leah K. Schutt, Maia Vinogradova, John Wai, Tao Wang, Ingrid E. Wertz, Jonathan R. White, Siew Kuen Yeap, Amy Young, Birong Zhang, Xiaoping Zheng, Wei Zhou, Yu Zhong & Xiaojing Wang. (2021) GDC-9545 (Giredestrant): A Potent and Orally Bioavailable Selective Estrogen Receptor Antagonist and Degrader with an Exceptional Preclinical Profile for ER+ Breast Cancer. Journal of Medicinal Chemistry 64:16, pages 11841-11856.
Crossref
Crossref
Ahmed Abdelhameed, Mei Feng, April C. Joice, Emilia M. Zywot, Yiru Jin, Chris La Rosa, Xiaoping Liao, Heidi L. Meeds, Yena Kim, Junan Li, Craig A. McElroy, Michael Zhuo Wang & Karl A. Werbovetz. (2021) Synthesis and Antileishmanial Evaluation of Arylimidamide–Azole Hybrids Containing a Phenoxyalkyl Linker. ACS Infectious Diseases 7:7, pages 1901-1922.
Crossref
Crossref
Kyoung Hwan Kim, Jeong-Woong Park, Young Mok Yang, Ki-Duk Song & Byung-wook Cho. (2021) Effect of methylsulfonylmethane on oxidative stress and CYP3A93 expression in fetal horse liver cells. Animal Bioscience 34:2, pages 312-319.
Crossref
Crossref
Sabrina T. Wiebe, Andreas Huennemeyer, Werner Kadus, Markus Goettel, Alen Jambrecina, Armin Schultz, Richard Vinisko, Laura Schlieker, Lena Herich & Gerd Mikus. (2020) Midazolam microdosing applied in early clinical development for drug–drug interaction assessment. British Journal of Clinical Pharmacology 87:1, pages 178-188.
Crossref
Crossref
Kevin M. Johnson, Dian Su & Donglu Zhang. 2021. Cytochrome P450. Cytochrome P450
27
54
.
Yutao Liu, Chang Liu, Yamei Liu, Quanli Ge & Chen Sun. (2020)
Cytochrome P450 Mediated Bioactivation of Rutaevin, a Bioactive and Potentially Hepatotoxic Component of
Evodia Rutaecarpa
. Chemical Research in Toxicology 33:12, pages 3054-3064.
Crossref
Crossref
Sabrina T. Wiebe, Andreas D. Meid & Gerd Mikus. (2020) Composite midazolam and 1′-OH midazolam population pharmacokinetic model for constitutive, inhibited and induced CYP3A activity. Journal of Pharmacokinetics and Pharmacodynamics 47:6, pages 527-542.
Crossref
Crossref
A. Berlińska, R. Świątkowska-Stodulska & K Sworczak. (2019) Factors Affecting Dexamethasone Suppression Test
Results. Experimental and Clinical Endocrinology & Diabetes 128:10, pages 667-671.
Crossref
Crossref
Delilah F.G. Hendriks, Sabine U. Vorrink, Tomas Smutny, Sarah C. Sim, Åsa Nordling, Shahid Ullah, Masaki Kumondai, Barry C. Jones, Inger Johansson, Tommy B. Andersson, Volker M. Lauschke & Magnus Ingelman‐Sundberg. (2020) Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three‐Dimensional Spheroid Cultures of Primary Human Hepatocytes. Clinical Pharmacology & Therapeutics 108:4, pages 844-855.
Crossref
Crossref
Hugues Chanteux, Maria Rosa, Claude Delatour, Johan Nicolaï, Eric Gillent, Sylvie Dell’Aiera & Anna-Lena Ungell. (2020) Application of Azamulin to Determine the Contribution of CYP3A4/5 to Drug Metabolic Clearance Using Human Hepatocytes. Drug Metabolism and Disposition 48:9, pages 778-787.
Crossref
Crossref
Xia Li, Lisa Junge, Max Taubert, Anabelle von Georg, Dominik Dahlinger, Chris Starke, Sebastian Frechen, Christoph Stelzer, Martina Kinzig, Fritz Sörgel, Ulrich Jaehde, Ulrich Töx, Tobias Goeser & Uwe Fuhr. (2020) A Novel Study Design Using Continuous Intravenous and Intraduodenal Infusions of Midazolam and Voriconazole for Mechanistic Quantitative Assessment of Hepatic and Intestinal CYP3A Inhibition. The Journal of Clinical Pharmacology 60:9, pages 1237-1253.
Crossref
Crossref
V. V. Smirnov, L. M. Krasnykh, G. F. Vasilenko, G. V. Ramenskaya & O. A. Checha. (2020) Use of endogenous cholesterol and its metabolite as markers of cyp450 metabolic activity. Medical Journal of the Russian Federation 26:2, pages 93-97.
Crossref
Crossref
John T. Wiernikowski & Melanie Brooke Bernhardt. (2020) Review of nutritional status, body composition, and effects of antineoplastic drug disposition. Pediatric Blood & Cancer 67:S3.
Crossref
Crossref
Catharine Avila, Ian Breakspear, Jason Hawrelak, Ses Salmond & Sue Evans. (2020) A systematic review and quality assessment of case reports of adverse events for borage (Borago officinalis), coltsfoot (Tussilago farfara) and comfrey (Symphytum officinale). Fitoterapia 142, pages 104519.
Crossref
Crossref
Joanna Brzeszczyńska, Filip Brzeszczyński, Kay Samuel, Katie Morgan, Steven D. Morley, John N. Plevris & Peter C. Hayes. (2020) Validation of Reference Genes for Gene Expression Studies by RT-qPCR in HepaRG Cells during Toxicity Testing and Disease Modelling. Cells 9:3, pages 770.
Crossref
Crossref
William C. Wright, Jude Chenge, Jingheng Wang, Hazel M. GirvanLei Yang, Sergio C. Chai, Andrew D. Huber, Jing Wu, Peter O. Oladimeji, Andrew W. Munro & Taosheng Chen. (2020) Clobetasol Propionate Is a Heme-Mediated Selective Inhibitor of Human Cytochrome P450 3A5. Journal of Medicinal Chemistry 63:3, pages 1415-1433.
Crossref
Crossref
Gaëlle Magliocco, Aurélien Thomas, Jules Desmeules & Youssef Daali. (2019) Phenotyping of Human CYP450 Enzymes by Endobiotics: Current Knowledge and Methodological Approaches. Clinical Pharmacokinetics 58:11, pages 1373-1391.
Crossref
Crossref
Reina Taguchi, Takafumi Naito, Naoko Kubono, Noriyoshi Ogawa, Hiroaki Itoh & Junichi Kawakami. (2019) Relationships between endogenous CYP3A markers and plasma amlodipine exposure and metabolism in early postpartum and non-peripartum women with hypertension. Pregnancy Hypertension 17, pages 209-215.
Crossref
Crossref
Yu-Jie Chen, Jian Zhang, Ping-Ping Zhu, Xian-Wen Tan, Qiu-Hong Lin, Wen-Xia Wang, Shan-Shan Yin, Ling-Zhi Gao, Ming-Ming Su, Chang-Xiao Liu, Liang Xu, Wei Jia, Irina F. Sevrioukova & Ke Lan. (2019) Stereoselective Oxidation Kinetics of Deoxycholate in Recombinant and Microsomal CYP3A Enzymes: Deoxycholate 19-Hydroxylation Is an In Vitro Marker of CYP3A7 Activity. Drug Metabolism and Disposition 47:6, pages 574-581.
Crossref
Crossref
Yuhan Xue, Junhao Li, Zengrui Wu, Guixia Liu, Yun Tang & Weihua Li. (2019)
Computational insights into the different catalytic activities of
CYP
3A4 and
CYP
3A5 toward
schisantherin E
. Chemical Biology & Drug Design 93:5, pages 854-864.
Crossref
Crossref
Juan Wang, Hongliang Ji, Helei Jia & Dongsheng Guan. (2019) Association between CYP3A4 gene rs4646437 polymorphism and the risk of hypertension in Chinese population: a case–control study. Bioscience Reports 39:4.
Crossref
Crossref
Kang Xiao, Jie Gao, Shi-Jia Weng, Yan Fang, Na Gao, Qiang Wen, Han Jin & Hai-Ling Qiao. (2018) CYP3A4/5 Activity Probed with Testosterone and Midazolam: Correlation between Two Substrates at the Microsomal and Enzyme Levels. Molecular Pharmaceutics 16:1, pages 382-392.
Crossref
Crossref
Mihirbaran Mandal, Kaushik Mitra, Diane Grotz, Xinjie Lin, Jairam Palamanda, Pramila Kumari, Alexei Buevich, John P. Caldwell, Xia Chen, Kathleen Cox, Leonard Favreau, Lynn Hyde, Matthew E. Kennedy, Reshma Kuvelkar, Xiaoxiang Liu, Robert D. Mazzola, Eric Parker, Diane Rindgen, Edward Sherer, Hongwu Wang, Zhaoning Zhu, Andrew W. Stamford & Jared N. Cumming. (2018) Overcoming Time-Dependent Inhibition (TDI) of Cytochrome P450 3A4 (CYP3A4) Resulting from Bioactivation of a Fluoropyrimidine Moiety. Journal of Medicinal Chemistry 61:23, pages 10700-10708.
Crossref
Crossref
Hiroki Okumura, Anna Nakanishi, Tadahiro Hashita, Takahiro Iwao & Tamihide Matsunaga. (2018) Effect of Celecoxib on Differentiation of Human Induced Pluripotent Stem Cells into Hepatocytes Involves STAT5 Activation. Drug Metabolism and Disposition 46:11, pages 1519-1527.
Crossref
Crossref
Kyoung-Ah Kim, In-Bae Park & Ji-Young Park. (2018) Effects of CYP2D6 and CYP3A5 genetic polymorphisms on steady-state pharmacokinetics and hemodynamic effects of tamsulosin in humans. European Journal of Clinical Pharmacology 74:10, pages 1281-1289.
Crossref
Crossref
Dae-Seop Shin, Hyewon Seo, Jung Yoon Yang, Jeongmin Joo, So Hee Im, Seong Soon Kim, Sang Kyum Kim & Myung Ae Bae. (2018) Quantitative Evaluation of Cytochrome P450 3A4 Inhibition and Hepatotoxicity in HepaRG 3-D Spheroids. International Journal of Toxicology 37:5, pages 393-403.
Crossref
Crossref
Cynthia M. Chavez-Eng, Ryan W. Lutz, Dina Goykhman & Kevin P. Bateman. (2018) Microdosing Cocktail Assay Development for Drug–Drug Interaction Studies. Journal of Pharmaceutical Sciences 107:7, pages 1973-1986.
Crossref
Crossref
Young Jae Choi, Ji-Yoon Lee, Chang Seon Ryu, Yong Ha Chi, Soo Heui Paik & Sang Kyum Kim. (2018) Role of cytochrome P450 enzymes in fimasartan metabolism in vitro. Food and Chemical Toxicology 115, pages 375-384.
Crossref
Crossref
Gideon Koren & Gali Pariente. (2018) Pregnancy- Associated Changes in Pharmacokinetics and their Clinical Implications. Pharmaceutical Research 35:3.
Crossref
Crossref
Daniela Gabbia, Arianna Dalla Pozza, Laura Albertoni, Roberta Lazzari, Giorgia Zigiotto, Maria Carrara, Vincenzo Baldo, Tatjana Baldovin, Annarosa Floreani & Sara De Martin. (2017) Pregnane X receptor and constitutive androstane receptor modulate differently CYP3A-mediated metabolism in early- and late-stage cholestasis. World Journal of Gastroenterology 23:42, pages 7519-7530.
Crossref
Crossref
Walter L. Miller. (2017) Steroidogenesis: Unanswered Questions. Trends in Endocrinology & Metabolism 28:11, pages 771-793.
Crossref
Crossref
Liang Yan, Yiting Wang, Jingyang Liu, Yali Nie, Xiao-bo Zhong, Quancheng Kan & Lirong Zhang. (2017) Alterations of Histone Modifications Contribute to Pregnane X Receptor-Mediated Induction of CYP3A4 by Rifampicin. Molecular Pharmacology 92:2, pages 113-123.
Crossref
Crossref
Jennifer Q. Dong, James R. Gosset, Odette A. Fahmi, Zhiwu Lin, Jeffrey R. Chabot, Steven G. Terra, Vu Le, Kristin Chidsey, Parya Nouri, Albert Kim, Leonard Buckbinder & Amit S. Kalgutkar. (2017) Examination of the Human Cytochrome P4503A4 Induction Potential of PF-06282999, an Irreversible Myeloperoxidase Inactivator: Integration of Preclinical, In Silico, and Biomarker Methodologies in the Prediction of the Clinical Outcome. Drug Metabolism and Disposition 45:5, pages 501-511.
Crossref
Crossref
V. Escudero-Vilaplana, A. Ribed, R.M. Romero-Jimenez, A. Herranz-Alonso & M. Sanjurjo-Saez. (2017) Pharmacotherapy follow-up of key points in the safety of oral antineoplastic agents. European Journal of Cancer Care 26:3, pages e12463.
Crossref
Crossref
S. W. Chan, Y. Xiao, M. Hu, O. Q. P. Yin, T. T. W. Chu, B. S. P. Fok, V. H. L. Lee & B. Tomlinson. (2016)
Associations of the
CYP3A5*3
and
CYP3A4
*
1G
polymorphisms with the pharmacokinetics of oral midazolam and the urinary 6β-hydroxycortisol/cortisol ratio as markers of CYP3A activity in healthy male Chinese
. Journal of Clinical Pharmacy and Therapeutics 41:5, pages 552-558.
Crossref
Crossref
Karin Skoglund, Johan Richter, Ulla Olsson-Strömberg, Jonas Bergquist, Warunika Aluthgedara, S. J. Kumari A. Ubhayasekera, Svante Vikingsson, Anna Svedberg, Stina Söderlund, Anna Sandstedt, Anders Johnsson, Jesper Aagesen, Jonas Alsenhed, Staffan Hägg, Curt Peterson, Kourosh Lotfi & Henrik Gréen. (2016) In Vivo Cytochrome P450 3A Isoenzyme Activity and Pharmacokinetics of Imatinib in Relation to Therapeutic Outcome in Patients With Chronic Myeloid Leukemia. Therapeutic Drug Monitoring 38:2, pages 230-238.
Crossref
Crossref
Yitong Liu & Michael F. Santillo. (2015) Cytochrome P450 2D6 and 3A4 enzyme inhibition by amine stimulants in dietary supplements. Drug Testing and Analysis 8:3-4, pages 307-310.
Crossref
Crossref
Cheryl S. Al-Mateen, Sandra J. Mullen & Jessica K. Malloy. 2016. Handbook of Mental Health in African American Youth. Handbook of Mental Health in African American Youth
39
61
.
Bita Mesgarpour, Ghazaleh Gouya, Harald Herkner, Berthold Reichardt & Michael Wolzt. (2015) A population-based analysis of the risk of drug interaction between clarithromycin and statins for hospitalisation or death. Lipids in Health and Disease 14:1.
Crossref
Crossref
Yitong Liu, Thomas J. Flynn, Menghang Xia, Paddy L. Wiesenfeld & Martine S. Ferguson. (2015) Evaluation of CYP3A4 inhibition and hepatotoxicity using DMSO-treated human hepatoma HuH-7 cells. Cell Biology and Toxicology 31:4-5, pages 221-230.
Crossref
Crossref
Xiaojing Wang, Minghua Sun, Connie New, Spencer Nam, Wesley P. Blackaby, Alastair J. Hodges, David Nash, Mizio Matteucci, Joseph P. Lyssikatos, Peter W. Fan, Suzanne Tay & Jae H. Chang. (2015) Probing Mechanisms of CYP3A Time-Dependent Inhibition Using a Truncated Model System. ACS Medicinal Chemistry Letters 6:8, pages 925-929.
Crossref
Crossref
Julie K. Drobish, Max B. Kelz, Patricia M. DiPuppo & Scott D. Cook-Sather. (2015) Emergence Delirium with Transient Associative Agnosia and Expressive Aphasia Reversed by Flumazenil in a Pediatric Patient. A & A Case Reports 4:11, pages 148-150.
Crossref
Crossref
Lingtak‐Neander Chan, Yvonne S. Lin, Jessica C. Tay‐Sontheimer, Dorothy Trawick, Brant K. Oelschlager, David R. Flum, Kristen K. Patton, Danny D. Shen & John R. Horn. (2015)
Proximal Roux‐en‐Y Gastric Bypass Alters Drug Absorption Pattern But Not Systemic Exposure of
CYP
3A4 and P‐glycoprotein Substrates
. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 35:4, pages 361-369.
Crossref
Crossref
Michael A. Zientek & Kuresh Youdim. (2015) Reaction Phenotyping: Advances in the Experimental Strategies Used to Characterize the Contribution of Drug-Metabolizing Enzymes. Drug Metabolism and Disposition 43:1, pages 163-181.
Crossref
Crossref
Yitong Liu & Thomas J. Flynn. (2015) CYP3A4 inhibition by Psoralea corylifolia and its major components in human recombinant enzyme, differentiated human hepatoma HuH-7 and HepaRG cells. Toxicology Reports 2, pages 530-534.
Crossref
Crossref
Shunji Imai, Yasuo Yoshioka, Yuki Morishita, Tokuyuki Yoshida, Miyuki Uji, Kazuya Nagano, Yohei Mukai, Haruhiko Kamada, Shin-ichi Tsunoda, Kazuma Higashisaka & Yasuo Tsutsumi. (2014) Size and surface modification of amorphous silica particles determine their effects on the activity of human CYP3A4 in vitro. Nanoscale Research Letters 9:1.
Crossref
Crossref
Dany Spaggiari, Laurent Geiser, Youssef Daali & Serge Rudaz. (2014) A cocktail approach for assessing the in vitro activity of human cytochrome P450s: An overview of current methodologies. Journal of Pharmaceutical and Biomedical Analysis 101, pages 221-237.
Crossref
Crossref
Lana Shaya, Chris Dejong & Joanna Y. Wilson. (2014) Expression patterns of cytochrome P450 3B and 3C genes in model fish species. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 166, pages 115-125.
Crossref
Crossref
V. Zancanella, M. Giantin & M. Dacasto. (2014) Absolute quantification and modulation of cytochrome P450 3A isoforms in cattle liver. The Veterinary Journal 202:1, pages 106-111.
Crossref
Crossref
Maria Konstandi, Elizabeth O. Johnson & Matti A. Lang. (2014) Consequences of psychophysiological stress on cytochrome P450-catalyzed drug metabolism. Neuroscience & Biobehavioral Reviews 45, pages 149-167.
Crossref
Crossref
Lotte M. Lang & Kristian Linnet. (2014)
The Ratio of 6β‐Hydroxycortisol to Cortisol in Urine as a Measure of Cytochrome
P
450 3
A
Activity in Postmortem Cases
. Journal of Forensic Sciences 59:4, pages 1036-1040.
Crossref
Crossref
Danuta Plewka, Andrzej Plewka, Tomasz Szczepanik, Michał Morek, Edyta Bogunia, Piotr Wittek & Czarosław Kijonka. (2014) Expression of selected cytochrome P450 isoforms and of cooperating enzymes in colorectal tissues in selected pathological conditions. Pathology - Research and Practice 210:4, pages 242-249.
Crossref
Crossref
Xiaohai Li, Valer Jeso, Scott Heyward, Gregory S. Walker, Raman Sharma, Glenn C. Micalizio & Michael D. Cameron. (2014)
Characterization of T-5
N
-Oxide Formation as the First Highly Selective Measure of CYP3A5 Activity
. Drug Metabolism and Disposition 42:3, pages 334-342.
Crossref
Crossref
Laura Dickinson, Masautso Chaponda, Daniel F. Carr, Joep J. van Oosterhout, Johnstone Kumwenda, David G. Lalloo, Munir Pirmohamed, Robert S. Heyderman & Saye H. Khoo. (2014) Population Pharmacokinetic and Pharmacogenetic Analysis of Nevirapine in Hypersensitive and Tolerant HIV-Infected Patients from Malawi. Antimicrobial Agents and Chemotherapy 58:2, pages 706-712.
Crossref
Crossref
Ye-Ji LimEun-Young ChaHye-Eun JungJong-Lyul GhimSu-Jun LeeEun-Young KimJae-Gook Shin. (2014) Genetic polymorphisms of CYP2C9, CYP2C19, CYP2D6, CYP3A4, and CYP3A5 in Vietnamese-Koreans. Translational and Clinical Pharmacology 22:2, pages 70.
Crossref
Crossref
Khaled Abass, Petri Reponen, Sampo Mattila, Arja Rautio & Olavi Pelkonen. (2014) Human variation and CYP enzyme contribution in benfuracarb metabolism in human in vitro hepatic models. Toxicology Letters 224:2, pages 300-309.
Crossref
Crossref
Joseph McGraw. 2014. Handbook of Pharmacogenomics and Stratified Medicine. Handbook of Pharmacogenomics and Stratified Medicine
323
340
.
Patricia N. Sidharta, Paul L. M. van Giersbergen & Jasper Dingemanse. (2013) Safety, tolerability, pharmacokinetics, and pharmacodynamics of macitentan, an endothelin receptor antagonist, in an ascending multiple‐dose study in healthy subjects. The Journal of Clinical Pharmacology 53:11, pages 1131-1138.
Crossref
Crossref
Ju-Yeon Moon, Se Mi Kang, Jeongae Lee, Joo-Youn Cho, Myeong Hee Moon, In-Jin Jang, Bong Chul Chung & Man Ho Choi. (2013) GC-MS–Based Quantitative Signatures of Cytochrome P450–Mediated Steroid Oxidation Induced by Rifampicin. Therapeutic Drug Monitoring 35:4, pages 473-484.
Crossref
Crossref
S.X. Hu. (2013) Effect of age on hepatic cytochrome P450 of Ross 708 broiler chickens. Poultry Science 92:5, pages 1283-1291.
Crossref
Crossref
Bernice Chabot-Giguère, Robert J. Letcher & Jonathan Verreault. (2013) In vitro biotransformation of decabromodiphenyl ether (BDE-209) and Dechlorane Plus flame retardants: A case study of ring-billed gull breeding in a pollution hotspot in the St. Lawrence River, Canada. Environment International 55, pages 101-108.
Crossref
Crossref
Karin C. S?derberg L?fdal, Marine L. Andersson & Lars L. Gustafsson. (2013) Cytochrome P450-Mediated Changes in Oxycodone Pharmacokinetics/Pharmacodynamics and Their Clinical Implications. Drugs 73:6, pages 533-543.
Crossref
Crossref
Ulrich M. Zanger & Matthias Schwab. (2013) Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation. Pharmacology & Therapeutics 138:1, pages 103-141.
Crossref
Crossref
Matthew B. Dufek, Beverly M. Knight, Arlene S. Bridges & Dhiren R. Thakker. (2013) P-Glycoprotein Increases Portal Bioavailability of Loperamide in Mouse by Reducing First-Pass Intestinal Metabolism. Drug Metabolism and Disposition 41:3, pages 642-650.
Crossref
Crossref
Guang-Bo Ge, Jing Ning, Liang-Hai Hu, Zi-Ru Dai, Jie Hou, Yun-Feng Cao, Zhen-Wen Yu, Chun-Zhi Ai, Jing-Kai Gu, Xiao-Chi Ma & Ling Yang. (2013) A highly selective probe for human cytochrome P450 3A4: isoform selectivity, kinetic characterization and its applications. Chemical Communications 49:84, pages 9779.
Crossref
Crossref
Hong-Guang Xie & Ying-Dong Zhang. 2013. Omics for Personalized Medicine. Omics for Personalized Medicine
469
506
.
Lotte M. Lang, Petur W. Dalsgaard & Kristian Linnet. (2012)
Quantitative analysis of cortisol and 6β‐hydroxycortisol in urine by fully automated
SPE
and ultra‐performance
LC
coupled with electrospray and atmospheric pressure chemical ionization (
ESC
i)‐
TOF
‐
MS
. Journal of Separation Science 36:2, pages 246-251.
Crossref
Crossref
Hongmao Sun, Henrike Veith, Menghang Xia, Christopher P. Austin, Raymond R. Tice & Ruili Huang. (2012) Prediction of Cytochrome P450 Profiles of Environmental Chemicals with QSAR Models Built from Drug‐Like Molecules. Molecular Informatics 31:11-12, pages 783-792.
Crossref
Crossref
Hartmut Blode, Susan Zeun, Susanne Parke, Torsten Zimmermann, Beate Rohde, Uwe Mellinger & Michael Kunz. (2012) Evaluation of the effects of rifampicin, ketoconazole and erythromycin on the steady-state pharmacokinetics of the components of a novel oral contraceptive containing estradiol valerate and dienogest in healthy postmenopausal women. Contraception 86:4, pages 337-344.
Crossref
Crossref
Robert L. Walsky, R. Scott Obach, Ruth Hyland, Ping Kang, Sue Zhou, Michael West, Kieran F. Geoghegan, Christopher J. Helal, Gregory S. Walker, Theunis C. Goosen & Michael A. Zientek. (2012) Selective Mechanism-Based Inactivation of CYP3A4 by CYP3cide (PF-04981517) and Its Utility as an In Vitro Tool for Delineating the Relative Roles of CYP3A4 versus CYP3A5 in the Metabolism of Drugs. Drug Metabolism and Disposition 40:9, pages 1686-1697.
Crossref
Crossref
Ingolf Cascorbi. (2012) Drug Interactions. Deutsches Ärzteblatt international.
Crossref
Crossref
Kathrin Klein, Maria Thomas, Stefan Winter, Andreas K. Nussler, Mikko Niemi, Matthias Schwab & Ulrich M. Zanger. (2012) PPARA: A Novel Genetic Determinant of CYP3A4 In Vitro and In Vivo. Clinical Pharmacology & Therapeutics 91:6, pages 1044-1052.
Crossref
Crossref
Naoko NakamuraKumiko SaekiMasami MitsumotoSatoko MatsuyamaMiwako NishioKoichi SaekiMamoru HasegawaYoshiyuki MiyagawaHajime OhkitaNobutaka KiyokawaMasashi ToyodaHidenori AkutsuAkihiro UmezawaAkira Yuo. (2012) Feeder-Free and Serum-Free Production of Hepatocytes, Cholangiocytes, and Their Proliferating Progenitors from Human Pluripotent Stem Cells: Application to Liver-Specific Functional and Cytotoxic Assays. Cellular Reprogramming 14:2, pages 171-185.
Crossref
Crossref
Noor Al‐Dasooqi, Rachel J. Gibson, Joanne M. Bowen & Dorothy M. Keefe. 2012. Molecular and Cellular Therapeutics. Molecular and Cellular Therapeutics
69
102
.
Alexander V. LyubimovUlrich M. Zanger. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions
1
36
.
D. Allorge,G. Tournel,A. Garat. 2012. Traité De Toxicologie Médico-judiciaire. Traité De Toxicologie Médico-judiciaire
73
98
.
E D Kharasch, A Francis, A London, K Frey, T Kim & J Blood. (2011) Sensitivity of Intravenous and Oral Alfentanil and Pupillary Miosis as Minimal and Noninvasive Probes for Hepatic and First-Pass CYP3A Induction. Clinical Pharmacology & Therapeutics 90:1, pages 100-108.
Crossref
Crossref
Hong‐Guang Xie. 2011. Molecular Microbiology. Molecular Microbiology
803
832
.
Alfred Zimmerlin, Markus Trunzer & Bernard Faller. (2011) CYP3A Time-Dependent Inhibition Risk Assessment Validated with 400 Reference Drugs. Drug Metabolism and Disposition 39:6, pages 1039-1046.
Crossref
Crossref
Louise Borst, Sandra Wallerek, Kim Dalhoff, Kirsten K. Rasmussen, Finn Wesenberg, Peder S. Wehner & Kjeld Schmiegelow. (2011) The impact of CYP3A5*3 on risk and prognosis in childhood acute lymphoblastic leukemia. European Journal of Haematology 86:6, pages 477-483.
Crossref
Crossref
T E Mürdter, W Schroth, L Bacchus-Gerybadze, S Winter, G Heinkele, W Simon, P A Fasching, T Fehm, M Eichelbaum, M Schwab & H Brauch. (2011) Activity Levels of Tamoxifen Metabolites at the Estrogen Receptor and the Impact of Genetic Polymorphisms of Phase I and II Enzymes on Their Concentration Levels in Plasma. Clinical Pharmacology & Therapeutics 89:5, pages 708-717.
Crossref
Crossref
E D Kharasch, S Vangveravong, N Buck, A London, T Kim, J Blood & R H Mach. (2011) Concurrent Assessment of Hepatic and Intestinal Cytochrome P450 3A Activities Using Deuterated Alfentanil. Clinical Pharmacology & Therapeutics 89:4, pages 562-570.
Crossref
Crossref
Satoshi Yamaori, Juri Ebisawa, Yoshimi Okushima, Ikuo Yamamoto & Kazuhito Watanabe. (2011) Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: Role of phenolic hydroxyl groups in the resorcinol moiety. Life Sciences 88:15-16, pages 730-736.
Crossref
Crossref
Ulrike Olszewski, Richard Liedauer, Christoph Ausch, Theresia Thalhammer & Gerhard Hamilton. (2011) Overexpression of CYP3A4 in a COLO 205 Colon Cancer Stem Cell Model in vitro. Cancers 3:1, pages 1467-1479.
Crossref
Crossref
Hong-Guang Xie, Jian-Jun Zou, Zuo-Ying Hu, Jun-Jie Zhang, Fei Ye & Shao-Liang Chen. (2011) Individual variability in the disposition of and response to clopidogrel: Pharmacogenomics and beyond. Pharmacology & Therapeutics 129:3, pages 267-289.
Crossref
Crossref
Nils Vethe, Karsten Midtvedt, Anders Åsberg, Rune Amundsen & Stein Bergan. (2011) Legemiddelinteraksjoner og immunsuppresjon hos organtransplanterte. Tidsskrift for Den norske legeforening 131:20, pages 2000-2003.
Crossref
Crossref
Matthias Unger. (2011) Pharmakokinetische Arzneimittelinteraktionen zwischen Tumortherapeutika und Arzneimitteln der Komplementären Medizin: Mechanismen und klinische Relevanz. Forschende Komplementärmedizin / Research in Complementary Medicine 18:4, pages 213-218.
Crossref
Crossref
Oliver Kummer, Felix Hammann, Claudine Moser, Olivier Schaller, Jürgen Drewe & Stephan Krähenbühl. (2010) Effect of the inhibition of CYP3A4 or CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone. European Journal of Clinical Pharmacology 67:1, pages 63-71.
Crossref
Crossref
David J. Greenblatt. 2011. Drug Interactions in Infectious Diseases. Drug Interactions in Infectious Diseases
1
10
.
Haiping Hao, Li Lai, Chaonan Zheng, Qiong Wang, Guo Yu, Xueyan Zhou, Liang Wu, Ping Gong & Guangji Wang. (2010) Microsomal Cytochrome P450-Mediated Metabolism of Protopanaxatriol Ginsenosides: Metabolite Profile, Reaction Phenotyping, and Structure-Metabolism Relationship. Drug Metabolism and Disposition 38:10, pages 1731-1739.
Crossref
Crossref
S. H. Lee, J. S. Kang, J. S. Min, K. S. Yoon, J. P. Strycharz, R. Johnson, O. Mittapalli, V. M. Margam, W. Sun, H.‐M. Li, J. Xie, J. Wu, E. F. Kirkness, M. R. Berenbaum, B. R. Pittendrigh & J. M. Clark. (2010) Decreased detoxification genes and genome size make the human body louse an efficient model to study xenobiotic metabolism. Insect Molecular Biology 19:5, pages 599-615.
Crossref
Crossref
Kyoung-Ah Kim & Ji-Young Park. (2010) Effect of metronidazole on the pharmacokinetics of fexofenadine, a P-glycoprotein substrate, in healthy male volunteers. European Journal of Clinical Pharmacology 66:7, pages 721-725.
Crossref
Crossref
Khaled Abass, Petri Reponen, Sampo Mattila & Olavi Pelkonen. (2010) Metabolism of carbosulfan II. Human interindividual variability in its in vitro hepatic biotransformation and the identification of the cytochrome P450 isoforms involved. Chemico-Biological Interactions 185:3, pages 163-173.
Crossref
Crossref
Michael D. Coleman. 2010. Human Drug Metabolism. Human Drug Metabolism
319
327
.
Shinichiro Hanada, Natasha T. Snider, Elizabeth M. Brunt, Paul F. Hollenberg & M. Bishr Omary. (2010) Gender Dimorphic Formation of Mouse Mallory–Denk Bodies and the Role of Xenobiotic Metabolism and Oxidative Stress. Gastroenterology 138:4, pages 1607-1617.
Crossref
Crossref
Zhang Hong, Fang Yu, Li Ying & Liang Aibin. (2010) A highly sensitive SPE- liquid/liquid extraction – RPLC analytical method for the determination of 6β-hydroxycortisol and cortisol in cancer patients' urine. Journal of Medical Colleges of PLA 25:2, pages 75-83.
Crossref
Crossref
Jakob Jornil, Klaus Gjervig Jensen, Frank Larsen & Kristian Linnet. (2010) Identification of Cytochrome P450 Isoforms Involved in the Metabolism of Paroxetine and Estimation of Their Importance for Human Paroxetine Metabolism Using a Population-Based Simulator. Drug Metabolism and Disposition 38:3, pages 376-385.
Crossref
Crossref
Ursula Lutz, Nataly Bittner, Mike Ufer & Werner K. Lutz. (2010) Quantification of cortisol and 6 beta-hydroxycortisol in human urine by LC-MS/MS, and gender-specific evaluation of the metabolic ratio as biomarker of CYP3A activity. Journal of Chromatography B 878:1, pages 97-101.
Crossref
Crossref
K.K. Wolf, M.F. Paine & P.B. Watkins. 2010. Comprehensive Toxicology. Comprehensive Toxicology
53
75
.
Punit H. Marathe & A. David Rodrigues. 2010. Multi-Drug Resistance in Cancer. Multi-Drug Resistance in Cancer
385
403
.
Silvio Caccia, Silvio Garattini, Luca Pasina & Alessandro Nobili. (2009) Predicting the Clinical Relevance of Drug Interactions From Pre-Approval Studies. Drug Safety 32:11, pages 1017-1039.
Crossref
Crossref
Akihiro Hisaka, Makiko Kusama, Yoshiyuki Ohno, Yuichi Sugiyama & Hiroshi Suzuki. (2009) A Proposal for a Pharmacokinetic Interaction Significance Classification System (PISCS) Based on Predicted Drug Exposure Changes and Its Potential Application to Alert Classifications in Product Labelling. Clinical Pharmacokinetics 48:10, pages 653-666.
Crossref
Crossref
J Miao, Y Jin, R L Marunde, S Kim, S Quinney, M Radovich, L Li & S D Hall. (2009) Association of genotypes of the CYP3A cluster with midazolam disposition in vivo. The Pharmacogenomics Journal 9:5, pages 319-326.
Crossref
Crossref
Stacy S. ShordKanan Shah & Alvina Lukose. (2009) Drug—Botanical Interactions: A Review of the Laboratory, Animal, and Human Data for 8 Common Botanicals. Integrative Cancer Therapies 8:3, pages 208-227.
Crossref
Crossref
Anand K. Deo & Stelvio M. Bandiera. (2009) 3-Ketocholanoic Acid Is the Major in Vitro Human Hepatic Microsomal Metabolite of Lithocholic Acid. Drug Metabolism and Disposition 37:9, pages 1938-1947.
Crossref
Crossref
Xue-Hui Zhu, Jian-Jie Jiao, Cai-Li Zhang, Jian-Shi Lou & Chang-Xiao Liu. (2009) Limited sampling strategy in rats to predict the inhibited activities of hepatic CYP3A. Laboratory Animals 43:3, pages 284-290.
Crossref
Crossref
Jonathan Verreault, Robert J. Letcher, Christian Sonne & Rune Dietz. (2009) In vitro metabolism of polychlorinated biphenyls and cytochrome P450 monooxygenase activities in dietary-exposed Greenland sledge dogs. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 150:1, pages 91-100.
Crossref
Crossref
Irena ShvartsmanTal DvirTamar Harel-AdarSmadar Cohen. (2009) Perfusion Cell Seeding and Cultivation Induce the Assembly of Thick and Functional Hepatocellular Tissue-like Construct. Tissue Engineering Part A 15:4, pages 751-760.
Crossref
Crossref
Giovanni Tarantino, Matteo Nicola Dario Di Minno & Domenico Capone. (2009) Drug-induced liver injury: Is it somehow foreseeable?. World Journal of Gastroenterology 15:23, pages 2817.
Crossref
Crossref
Jonathan Verreault, France Maisonneuve, Rune Dietz, Christian Sonne & Robert J. Letcher. (2009)
Comparative hepatic activity of xenobiotic‐metabolizing enzymes and concentrations of organohalogens and their hydroxylated analogues in captive greenland sledge dogs (
Canis familiaris
)
. Environmental Toxicology and Chemistry 28:1, pages 162-172.
Crossref
Crossref
A. PESONEN, R. SUOJARANTA‐YLINEN, E. HAMMARÉN, P. TARKKILA, T. SEPPÄLÄ & P. H. ROSENBERG. (2008) Comparison of effects and plasma concentrations of opioids between elderly and middle‐aged patients after cardiac surgery. Acta Anaesthesiologica Scandinavica 53:1, pages 101-108.
Crossref
Crossref
Yuko Yamazaki, Hiroko Hashida, Anna Arita, Keiko Hamaguchi & Fumio Shimura. (2008) High dose of commercial products of kava (Piper methysticum) markedly enhanced hepatic cytochrome P450 1A1 mRNA expression with liver enlargement in rats. Food and Chemical Toxicology 46:12, pages 3732-3738.
Crossref
Crossref
Ulrich M. Zanger, Miia Turpeinen, Kathrin Klein & Matthias Schwab. (2008) Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation. Analytical and Bioanalytical Chemistry 392:6, pages 1093-1108.
Crossref
Crossref
Andreas Umgelter, Fabian Geisler & Ewert Schulte-Frohlinde. (2008) Die Überwachung der Leberfunktionen in der IntensivmedizinMonitoring liver functions in the intensive care unit. Intensivmedizin und Notfallmedizin 45:7, pages 413-423.
Crossref
Crossref
Olavi Pelkonen, Miia Turpeinen, Jukka Hakkola, Paavo Honkakoski, Janne Hukkanen & Hannu Raunio. (2008) Inhibition and induction of human cytochrome P450 enzymes: current status. Archives of Toxicology 82:10, pages 667-715.
Crossref
Crossref