Citations (35)
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H. Verma, J. Doshi, G. Narendra, B. Raju, P.K. Singh & O. Silakari. (2023) Energy decomposition and waterswapping analysis to investigate the SNP associated DPD mediated 5-FU resistance. SAR and QSAR in Environmental Research 34:1, pages 39-64.
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Diana Dimunová, Petra Matoušková, Radka Podlipná, Iva Boušová & Lenka Skálová. (2022) The role of UDP-glycosyltransferases in xenobioticresistance. Drug Metabolism Reviews 54:3, pages 282-298.
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Dan Liu, Qi Yu, Qing Ning, Zhongqiu Liu & Jie Song. (2022) The relationship between UGT1A1 gene & various diseases and prevention strategies. Drug Metabolism Reviews 54:1, pages 1-21.
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Baddipadige Raju, Shalki Choudhary, Gera Narendra, Himanshu Verma & Om Silakari. (2021) Molecular modeling approaches to address drug-metabolizing enzymes (DMEs) mediated chemoresistance: a review. Drug Metabolism Reviews 53:1, pages 45-75.
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Sanjay Kumar Paul, Abdelmadjid Guendouzi, Agniswar Banerjee, Abdelkrim Guendouzi & Rajen Haldar. Identification of approved drugs with ALDH1A1 inhibitory potential aimed at enhancing chemotherapy sensitivity in cancer cells: an in-silico drug repurposing approach. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-15.
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Articles from other publishers (30)
Xiaoxuan Yao, Jianping Mao, Haoyu Zhang, Yi Xiao, Yongjun Wang & Hongzhuo Liu. (2024) Development of novel N-aryl-2,4-bithiazole-2-amine-based CYP1B1 degraders for reversing drug resistance. European Journal of Medicinal Chemistry 272, pages 116488.
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Isabel S. Barata, José Rueff, Michel Kranendonk & Francisco Esteves. (2024) Pleiotropy of Progesterone Receptor Membrane Component 1 in Modulation of Cytochrome P450 Activity. Journal of Xenobiotics 14:2, pages 575-603.
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Isabely Mayara da Silva, Beatriz Geovana Leite Vacario, Nádia Calvo Martins Okuyama, Gustavo Rafael Mazzaron Barcelos, Paulo Emílio Fuganti, Roberta Losi Guembarovski, Ilce Mara de Syllos Cólus & Juliana Mara Serpeloni. (2024) Polymorphisms in drug-metabolizing genes and urinary bladder cancer susceptibility and prognosis: Possible impacts and future management. Gene 907, pages 148252.
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Gera Narendra, Baddipadige Raju, Himanshu Verma, Manoj Kumar, Subheet Kumar Jain, Gurleen Kaur Tung, Shubham Thakur, Rasdeep Kaur, Satwinderjeet Kaur, Bharti Sapra & Om Silakari. (2024) Scaffold hopping based designing of selective ALDH1A1 inhibitors to overcome cyclophosphamide resistance: synthesis and biological evaluation. RSC Medicinal Chemistry 15:1, pages 309-321.
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Baddipadige Raju, Bharti Sapra & Om Silakari. (2022) 3D-QSAR assisted identification of selective CYP1B1 inhibitors: an effective bioisosteric replacement/molecular docking/electrostatic complementarity analysis. Molecular Diversity 27:6, pages 2673-2693.
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Yue Wu, Jin-Hui Shi, Guang-Hao Zhu, Yuan Xiong, Jia-Hao Gong, Hui-Zhen Wei, Zhao-Bin Guo, Zi-Ru Dai, Xiao-Bo Sun & Guang-Bo Ge. (2023) Discovery of 4’-trifluoromethylchalcones as novel, potent and selective hCYP1B1 inhibitors without concomitant AhR activation. European Journal of Medicinal Chemistry 258, pages 115552.
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Alzbeta Spalenkova, Marie Ehrlichova, Shouzou Wei, F. Peter Guengerich & Pavel Soucek. (2023) Effects of 7-ketocholesterol on tamoxifen efficacy in breast carcinoma cell line models in vitro. The Journal of Steroid Biochemistry and Molecular Biology 232, pages 106354.
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Baddipadige Raju, Himanshu Verma, Gera Narendra, Gurleen Kaur, Subheet Kumar Jain & Om Silakari. (2023)
Identification of potential benzoxazolinones as CYP1B1 inhibitors
via
molecular docking, dynamics, waterswap, and
in vitro
analysis
. New Journal of Chemistry 47:26, pages 12339-12349.
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Gera Narendra, Baddipadige Raju, Himanshu Verma, Manoj Kumar, Subheet Kumar Jain, Gurleen Kaur Tung, Shubham Thakur, Rasdeep Kaur, Satwinderjeet Kaur, Bharti Sapra, Pankaj Kumar Singh & Om Silakari. (2023) Raloxifene and bazedoxifene as selective ALDH1A1 inhibitors to ameliorate cyclophosphamide resistance: A drug repurposing approach. International Journal of Biological Macromolecules 242, pages 124749.
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Zi‐Ning Lei, Qin Tian, Qiu‐Xu Teng, John N. D. Wurpel, Leli Zeng, Yihang Pan & Zhe‐Sheng Chen. (2023) Understanding and targeting resistance mechanisms in cancer. MedComm 4:3.
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Homeyra Seydi, Kosar Nouri, Niloufar Rezaei, Atena Tamimi, Moustapha Hassan, Hamed Mirzaei & Massoud Vosough. (2023) Autophagy orchestrates resistance in hepatocellular carcinoma cells. Biomedicine & Pharmacotherapy 161, pages 114487.
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Xu Zhou, Ramkrishna Mitra, Fei Hou, Shunheng Zhou, Lihong Wang & Wei Jiang. (2023) Genomic Landscape and Potential Regulation of RNA Editing in Drug Resistance. Advanced Science 10:14.
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Giorgio Malpeli, Stefano Barbi, Giulio Innamorati, Mariella Alloggio, Federica Filippini, Ilaria Decimo, Claudia Castelli, Roberto Perris & Maria Bencivenga. (2022) Landscape of Druggable Molecular Pathways Downstream of Genomic CDH1/Cadherin-1 Alterations in Gastric Cancer. Journal of Personalized Medicine 12:12, pages 2006.
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Hector Mayani, Antonieta Chávez-González, Karla Vázquez-Santillan, Jorge Contreras & Monica L Guzman. (2022) Cancer Stem Cells: Biology and Therapeutic Implications. Archives of Medical Research 53:8, pages 770-784.
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Himanshu Verma, Gera Narendra, Baddipadige Raju, Pankaj Kumar Singh & Om Silakari. (2022) Dihydropyrimidine Dehydrogenase-Mediated Resistance to 5-Fluorouracil: Mechanistic Investigation and Solution. ACS Pharmacology & Translational Science 5:11, pages 1017-1033.
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Gera Narendra, Shalki Choudhary, Baddipadige Raju, Himanshu Verma & Om Silakari. (2022) Role of Genetic Polymorphisms in Drug-Metabolizing Enzyme-Mediated Toxicity and Pharmacokinetic Resistance to Anti-Cancer Agents: A Review on the Pharmacogenomics Aspect. Clinical Pharmacokinetics 61:11, pages 1495-1517.
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Mitsuki Kondo, Yoshinori Ikenaka, Shouta M. M. Nakayama, Yusuke K. Kawai & Mayumi Ishizuka. (2022) Specific Gene Duplication and Loss of Cytochrome P450 in Families 1-3 in Carnivora (Mammalia, Laurasiatheria). Animals 12:20, pages 2821.
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Himanshu Verma, Gera Narendra, Baddipadige Raju, Manoj Kumar, Subheet K. Jain, Gurleen K. Tung, Pankaj K. Singh & Om Silakari. (2022)
3D‐QSAR and scaffold hopping based designing of benzo[
d
]ox‐azol‐2(3
H
)‐one and 2‐oxazolo[4,5‐
b
]pyridin‐2(3
H
)‐one derivatives as selective aldehyde dehydrogenase 1A1 inhibitors: Synthesis and biological evaluation
. Archiv der Pharmazie 355:9.
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Matheus Lohan-Codeço, Maria Luísa Barambo-Wagner, Luiz Eurico Nasciutti, Luis Felipe Ribeiro Pinto, Nathalia Meireles Da Costa & Antonio PalumboJrJr. (2022) Molecular mechanisms associated with chemoresistance in esophageal cancer. Cellular and Molecular Life Sciences 79:2.
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Arun Kanakkanthara & John H. Miller. (2021) βIII-tubulin overexpression in cancer: Causes, consequences, and potential therapies. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1876:2, pages 188607.
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Mingzhe Zhao, Jingsong Ma, Mo Li, Yingtian Zhang, Bixuan Jiang, Xianglong Zhao, Cong Huai, Lu Shen, Na Zhang, Lin He & Shengying Qin. (2021) Cytochrome P450 Enzymes and Drug Metabolism in Humans. International Journal of Molecular Sciences 22:23, pages 12808.
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Basudeb Das, Neha Jain & Bibekanand Mallick. (2021) piR-39980 mediates doxorubicin resistance in fibrosarcoma by regulating drug accumulation and DNA repair. Communications Biology 4:1.
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Gera Narendra, Baddipadige Raju, Himanshu Verma & Om Silakari. (2021) Identification of potential genes associated with ALDH1A1 overexpression and cyclophosphamide resistance in chronic myelogenous leukemia using network analysis. Medical Oncology 38:10.
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Gera Narendra, Baddipadige Raju, Himanshu Verma, Bharti Sapra & Om Silakari. (2021) Multiple machine learning models combined with virtual screening and molecular docking to identify selective human ALDH1A1 inhibitors. Journal of Molecular Graphics and Modelling 107, pages 107950.
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Yurong Song, Chenxi Li, Guangzhi Liu, Rui Liu, Youwen Chen, Wen Li, Zhiwen Cao, Baosheng Zhao, Cheng Lu & Yuanyan Liu. (2021) Drug-Metabolizing Cytochrome P450 Enzymes Have Multifarious Influences on Treatment Outcomes. Clinical Pharmacokinetics 60:5, pages 585-601.
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Miguel Angel Merlos Rodrigo, Hana Michalkova, Vladislav Strmiska, Berta Casar, Piero Crespo, Vivian de los Rios, J. Ignacio Casal, Yazan Haddad, Roman Guran, Tomas Eckschlager, Petra Pokorna, Zbynek Heger & Vojtech Adam. (2021) Metallothionein-3 promotes cisplatin chemoresistance remodelling in neuroblastoma. Scientific Reports 11:1.
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Yanyan Li, Jungang Zhao, Xiaoli Wu, Yini Zhang, Yin Jin & Weiyang Cai. (2021) Clinical and genomic characteristics of metabolic syndrome in colorectal cancer. Aging 13:4, pages 5442-5460.
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Pavlína Kellerová, Lucie Raisová Stuchlíková, Petra Matoušková, Karolína Štěrbová, Jiří Lamka, Martina Navrátilová, Ivan Vokřál, Barbora Szotáková & Lenka Skálová. (2020) Sub-lethal doses of albendazole induce drug metabolizing enzymes and increase albendazole deactivation in Haemonchus contortus adults. Veterinary Research 51:1.
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Himanshu Verma & Om Silakari. (2020) Investigating the Role of Missense SNPs on ALDH 1A1 mediated pharmacokinetic resistance to cyclophosphamide. Computers in Biology and Medicine 125, pages 103979.
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Mariana Bleker de Oliveira, Vasilij Koshkin, Geoffrey Liu & Sergey N. Krylov. (2020) Analytical Challenges in Development of Chemoresistance Predictors for Precision Oncology. Analytical Chemistry 92:18, pages 12101-12110.
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