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Drug Metabolism Reviews Volume 51, 2019 - Issue 4
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Review Articles

Bioactivation of herbal constituents: mechanisms and toxicological relevance

Bo WenDepartment of Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Collegeville, PA, USACorrespondence[email protected]
&
Peter GoryckiDepartment of Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Collegeville, PA, USA
Pages 453-497 | Received 05 Jun 2019, Accepted 08 Aug 2019, Published online: 26 Aug 2019

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Caiqin Yan, Ting Peng, Tingting Zhang, Yuan Wang, Na Li, Kai Wang & Xijuan Jiang. (2023) Molecular mechanisms of hepatotoxicity induced by compounds occurring in Evodiae Fructus. Drug Metabolism Reviews 55:1-2, pages 75-93.
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Articles from other publishers (11)

Johanna Yli‐Öyrä, Risto O. Juvonen, Marko Lehtonen, Mikko Herrala, Moshe Finel, Riikka Räisänen & Jaana Rysä. (2024) Anthraquinone biocolourant dermocybin is metabolized whereas dermorubin is not in in vitro liver fractions and recombinant metabolic enzymes. Basic & Clinical Pharmacology & Toxicology 134:6, pages 846-857.
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Yuqian Chi, Xiaoliang Zhu, Yaxuan Chen, Xin Li, Ziyi Jiang, Xiaoyang Jian, Mengyuan Lian, Xiaodi Wu, Lei Wang, Mengmeng Sun & Xiaowei Shi. (2024) Metabolic activation and cytochrome P450 inhibition of piperlonguminine mediated by CYP3A4. International Journal of Biological Macromolecules 268, pages 131502.
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Chester Yan Jie Ng, Yan Zhao, Ning Wang, Kwan Leung Chia, Chun Huat Teo, William Peh, Pansy Yeo & Linda L. D. Zhong. (2024) A multi-center cross-sectional study of Chinese Herbal Medicine-Drug adverse reactions using active surveillance in Singapore’s Traditional Chinese Medicine clinics. Chinese Medicine 19:1.
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Magdalena Bartnik. (2024) Methoxyfuranocoumarins of Natural Origin–Updating Biological Activity Research and Searching for New Directions—A Review. Current Issues in Molecular Biology 46:1, pages 856-883.
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Min Zhang, Xu-Dong Hou, Wei Liu, Lu Wang, Mei-Fang Jiang, Jie Hou, Hui Tang & Guang-Bo Ge. (2023) Uncovering the anti-obesity constituents in Ginkgo biloba extract and deciphering their synergistic effects. Fitoterapia 171, pages 105669.
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Maria Ponticelli, Maria Laura Bellone, Valentina Parisi, Annamaria Iannuzzi, Alessandra Braca, Nunziatina de Tommasi, Daniela Russo, Annalisa Sileo, Paola Quaranta, Giulia Freer, Mauro Pistello & Luigi Milella. (2023) Specialized metabolites from plants as a source of new multi-target antiviral drugs: a systematic review. Phytochemistry Reviews 22:3, pages 615-693.
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Kun Ren, Chuhao Zhang, Meihan Liu, Huiyuan Gao, Shumeng Ren, Dongmei Wang, Zhong Yuan, Yingni Pan & Xiaoqiu Liu. (2023) The attenuation effect of licorice on the hepatotoxicity of Euodiae Fructus by inhibiting the formation of protein conjugates and GSH depletion. Journal of Ethnopharmacology 308, pages 116307.
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Xiao Li, Dengyang Yin & Ying Sun. (2022) Identification of the metabolite of ophiopogonanone A by liquid chromatography/quadrupole time‐of‐flight mass spectrometry. Rapid Communications in Mass Spectrometry 36:12.
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Mohammad Fazil & Sadia Nikhat. (2020) Exploring new horizons in health care: A mechanistic review on the potential of Unani medicines in combating epidemics of infectious diseases. Phytotherapy Research 35:5, pages 2317-2335.
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Cigdem Kahraman, Zekiye Ceren Arituluk & Iffet Irem Tatli Cankaya. 2021. Medical Toxicology. Medical Toxicology.
Jeffrey D. Peterson. 2021. Nutraceuticals. Nutraceuticals 363 377 .

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