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Drug Metabolism Reviews Volume 53, 2021 - Issue 2: Next Generation Drug Discovery and Development: Rethinking Translational Pharmacology for Accelerated Drug Development
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Review Articles

Recent developments in predicting CYP-independent metabolism

Nikhilesh V. Dhuriaa Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE, USAView further author information
,
Bianka Harob School of Medicine and Health Sciences, The George Washington University, Washington, DC, USAView further author information
,
Amit Kapadiac California Poison Control Center, University of California San Francisco, San Diego, CA, USAView further author information
,
Khadjia A. Lobod Roots Community Health Center, Oakland, CA, USAView further author information
,
Bernice Matusowe Department of Drug Metabolism and Pharmacokinetics, Plexxikon Inc, Berkeley, CA, USAView further author information
,
Mary A. Schleifff Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USAORCID Iconhttps://orcid.org/0000-0003-3594-6835View further author information
ORCID Icon,
Christina Tantoye Department of Drug Metabolism and Pharmacokinetics, Plexxikon Inc, Berkeley, CA, USAView further author information
&
Jasleen K. Sodhie Department of Drug Metabolism and Pharmacokinetics, Plexxikon Inc, Berkeley, CA, USA;g Department of Bioengineering and Therapeutic Sciences, Schools of Pharmacy and Medicine, University of California, San Francisco, CA, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-6187-5597View further author information
ORCID Icon show all
Pages 188-206 | Received 22 Apr 2021, Accepted 23 Apr 2021, Published online: 25 May 2021

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Francesca Toselli, Melanie Golding, Johan Nicolaï, Eric Gillent & Hugues Chanteux. (2022) Drug clearance by aldehyde oxidase: can we avoid clinical failure?. Xenobiotica 52:8, pages 890-903.
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Articles from other publishers (4)

Agustos C. Ozbey, Stephen Fowler, Karen Leys, Pieter Annaert, Kenichi Umehara & Neil Parrott. (2024) Physiologically-Based Pharmacokinetic Modeling for Drugs Cleared by Non-Cytochrome P450 Enzymes: State-of-the-Art and Future Perspectives. Drug Metabolism and Disposition 52:1, pages 44-55.
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Vincent-Alexander Scholz, Conrad Stork, Markus Frericks & Johannes Kirchmair. (2023) Computational prediction of the metabolites of agrochemicals formed in rats. Science of The Total Environment 895, pages 165039.
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Mohit Sharma, Ankita Sharma, Shikha Thakur, Vijay K. Nuthakki, Ashiya Jamwal, Utpal Nandi, Hemant R. Jadhav & Sandip B. Bharate. (2023) Discovery of blood-brain barrier permeable and orally bioavailable caffeine-based amide derivatives as acetylcholinesterase inhibitors. Bioorganic Chemistry 139, pages 106719.
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Jingwei Zhang, Zhixia Qiu, Yongjie Zhang, Guangji Wang & Haiping Hao. (2023) Intracellular spatiotemporal metabolism in connection to target engagement. Advanced Drug Delivery Reviews 200, pages 115024.
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