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Drug Metabolism Reviews Volume 54, 2022 - Issue 3
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Review Articles

Biotransformation novel advances – 2021 year in review

S. Cyrus Khojasteha Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc, South San Francisco, CA, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-8385-9288
ORCID Icon,
Upendra A. Argikarb Non-clinical Development, Bill and Melinda Gates Medical Research Institute, Cambridge, MA, USAORCID Iconhttps://orcid.org/0000-0002-0939-0813
ORCID Icon,
Sungjoon Choa Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc, South San Francisco, CA, USAORCID Iconhttps://orcid.org/0000-0003-1215-9759
ORCID Icon,
Rachel Crouchc Department of Pharmaceutical Sciences, Lipscomb University College of Pharmacy and Health Sciences, Nashville, TN, USAORCID Iconhttps://orcid.org/0000-0002-4525-6072
ORCID Icon,
Carley J. S. Heckd Medicine Design, Pfizer Worldwide Research, Development and Medical, Groton, CT, USAORCID Iconhttps://orcid.org/0000-0002-6842-3670
ORCID Icon,
Kevin M. Johnsona Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc, South San Francisco, CA, USAORCID Iconhttps://orcid.org/0000-0003-0479-4242
ORCID Icon,
Amit S. Kalgutkare Medicine Design, Pfizer Worldwide Research, Development and Medical, Cambridge, MA, USAORCID Iconhttps://orcid.org/0000-0001-9701-756X
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Lloyd Kingf Quantitative Drug Discovery, UCB Biopharma UK, Slough, UKORCID Iconhttps://orcid.org/0000-0002-3301-7533
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Hlaing (Holly) Mawg Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USAORCID Iconhttps://orcid.org/0000-0002-4051-7958
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Herana Kamal Seneviratneh Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USAORCID Iconhttps://orcid.org/0000-0002-7221-7060
ORCID Icon,
Shuai Wanga Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc, South San Francisco, CA, USAORCID Iconhttps://orcid.org/0000-0002-3282-1343
ORCID Icon,
Cong Weii Drug Metabolism and Pharmacokinetics, Biogen Inc, Cambridge, MA, USAORCID Iconhttps://orcid.org/0000-0003-2310-9255
ORCID Icon,
Donglu Zhanga Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc, South San Francisco, CA, USA
&
Klarissa D. Jacksonj Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, Chapel Hill, NC, USAORCID Iconhttps://orcid.org/0000-0002-9388-9800
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Pages 207-245 | Received 03 May 2022, Accepted 29 Jun 2022, Published online: 30 Aug 2022

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S. Cyrus Khojasteh, Upendra A. Argikar, Lionel Cheruzel, Sungjoon Cho, Rachel D. Crouch, Deepika Dhaware, Carley J. S. Heck, Kevin M. Johnson, Amit S. Kalgutkar, Lloyd King, Joyce Liu, Bin Ma, Hlaing Maw, Grover P. Miller, Herana Kamal Seneviratne, Ryan H. Takahashi, Shuai Wang, Cong Wei & Klarissa D. Jackson. (2023) Biotransformation research advances – 2022 year in review. Drug Metabolism Reviews 55:4, pages 301-342.
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Articles from other publishers (2)

Dan Qin & Jinyan Dong. (2023) Multi-Level Optimization and Strategies in Microbial Biotransformation of Nature Products. Molecules 28:6, pages 2619.
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M. Keerthana & M. Vidyavathi. (2022) Fungal Biotransformation of Chlordiazepoxide and Evaluation of Type and Kinetics of Fungal Enzyme. Journal of Pure and Applied Microbiology 16:4, pages 2836-2850.
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