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Experimental Aging Research
An International Journal Devoted to the Scientific Study of the Aging Process
Volume 1, 1975 - Issue 2
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Original Articles

Behavioral differences in young and aged mice: Strain differences for activity measures, operant learning, sensory discrimination, and alcohol preference

Charles L. Goodrick Gerontology Research Center Baltimore City Hospitals Baltimore, Maryland, 21224
Pages 191-207 | Received 28 Jul 1975, Accepted 02 Sep 1975, Published online: 27 Sep 2007

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Nadine Fresquet & Jean Médioni. (1993) Effects of ageing on visual discrimination learning in Drosophila melanogaster . The Quarterly Journal of Experimental Psychology Section B 46:4, pages 399-412.
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PeterJ. Donovick & RichardG. Burright. (1986) Short term lead exposure, age and food deprivation: Interactive effects on wheel running behavior of adult male mice. Experimental Aging Research 12:3, pages 163-168.
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Marylou Cheal. (1986) The gerbil: A unique model for research on aging. Experimental Aging Research 12:1, pages 3-21.
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BarbaraW. Marquette, CarlW. Schneider & RichardA. Hartline. (1984) Age differences in the oxidation of and neural response to ethanol in mice. Experimental Aging Research 10:1, pages 7-11.
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DonaldK. Ingram. (1983) Toward the behavioral assessment of biological aging in the laboratory mouse: Concepts, terminology, and objectives. Experimental Aging Research 9:4, pages 225-238.
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DonaldK. Ingram, EdwardL. Spangler & GeorgeP. Vincent. (1983) Behavioral comparison of aged virgin and retired breeder mice. Experimental Aging Research 9:2, pages 111-113.
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J.M. Harrison. (1981) Effects of age on acquisition and maintenance of a location discrimination in rats. Experimental Aging Research 7:4, pages 467-476.
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ReginaldL. Dean, Joseph Scozzafava, J. Allen Goas, Barbara Regan, Bernard Beer & RaymondT. Bartus$suffix/text()$suffix/text(). (1981) Age-related differences in behavior across the life span of the C57BL/6J mouse. Experimental Aging Research 7:4, pages 427-451.
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W. Gibson Wood. (1976) Age-associated differences in response to alcohol in rats and mice: A biochemical and behavioral review. Experimental Aging Research 2:6, pages 543-562.
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W. Gibson Wood. (1976) Ethanol preference in C57BL/6 and BALB/c mice at three ages and eight ethanol concentrations. Experimental Aging Research 2:5, pages 425-434.
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Articles from other publishers (40)

Jhana O. Hendrickx, Sofie De Moudt, Elke Calus, Peter Paul De Deyn, Debby Van Dam & Guido R.Y. De Meyer. (2022) Age-related cognitive decline in spatial learning and memory of C57BL/6J mice. Behavioural Brain Research 418, pages 113649.
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Carola I. Radulescu, Veronika Cerar, Peter Haslehurst, Maksym Kopanitsa & Samuel J. Barnes. (2021) The aging mouse brain: cognition, connectivity and calcium. Cell Calcium 94, pages 102358.
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Hirotaka Shoji & Tsuyoshi Miyakawa. (2019) Age‐related behavioral changes from young to old age in male mice of a C57 BL /6J strain maintained under a genetic stability program . Neuropsychopharmacology Reports 39:2, pages 100-118.
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Angela N Henderson-Redmond, Tammy E Lowe, Xi B Tian & Daniel J Morgan. (2018) Increased ethanol drinking in “humanized” mice expressing the mu opioid receptor A118G polymorphism are mediated through sex-specific mechanisms. Brain Research Bulletin 138, pages 12-19.
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Heike Asseburg, Carmina Schäfer, Madeleine Müller, Stephanie Hagl, Maximilian Pohland, Dirk Berressem, Marta Borchiellini, Christina Plank & Gunter P. Eckert. (2016) Effects of Grape Skin Extract on Age-Related Mitochondrial Dysfunction, Memory and Life Span in C57BL/6J Mice. NeuroMolecular Medicine 18:3, pages 378-395.
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Daniel M. Krall, Stephanie L. Lim, Abby M. Cooper, Paul W. Burleson, Derek J. Rhoades, Stephen J. Jacquemin, Daryl C. Willmore, F. Martin Spears & Catherine B. Willmore. (2013) Withdrawal effect of chronic amphetamine exposure during adolescence on complex maze performance. Addiction Biology 19:4, pages 634-642.
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E. Kostrzewa & M. J. Kas. (2013) The use of mouse models to unravel genetic architecture of physical activity: a review. Genes, Brain and Behavior 13:1, pages 87-103.
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Andreas Fahlström, Hugo Zeberg & Brun Ulfhake. (2011) Changes in behaviors of male C57BL/6J mice across adult life span and effects of dietary restriction. AGE 34:6, pages 1435-1452.
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Brian M. Zanghi, Wendell Kerr, Christina de Rivera, Joseph A. Araujo & Norton W. Milgram. (2012) Effect of age and feeding schedule on diurnal rest/activity rhythms in dogs. Journal of Veterinary Behavior 7:6, pages 339-347.
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Christine M. Wooley, Shuqin Xing, Robert W. Burgess, Gregory A. Cox & Kevin L. Seburn. (2009) Age, experience and genetic background influence treadmill walking in mice. Physiology & Behavior 96:2, pages 350-361.
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T. Karl, L. Duffy, A. Scimone, R. P. Harvey & P. R. Schofield. (2006) Altered motor activity, exploration and anxiety in heterozygous neuregulin 1 mutant mice: implications for understanding schizophrenia. Genes, Brain and Behavior 6:7, pages 677-687.
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Najet Serradj & Marc Jamon. (2007) Age-related changes in the motricity of the inbred mice strains 129/sv and C57BL/6j. Behavioural Brain Research 177:1, pages 80-89.
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Gerald E. Mcclearn & Stephen A. Petrill. 2016. The Cambridge Handbook of Age and Ageing. The Cambridge Handbook of Age and Ageing 141 148 .
EL Abel. 2005. Comprehensive Handbook of Alcohol Related Pathology. Comprehensive Handbook of Alcohol Related Pathology 1551 1557 .
Peter A Gooderham, Raymonde F Gagnon & Kathryn Gill. (2004) Attenuation of the alcohol preference of C57BL/6 mice during chronic renal failure. Journal of Laboratory and Clinical Medicine 143:5, pages 292-300.
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Luca Bondolfi, Florian Ermini, Jefferey M Long, Donald K Ingram & Mathias Jucker. (2004) Impact of age and caloric restriction on neurogenesis in the dentate gyrus of C57BL/6 mice. Neurobiology of Aging 25:3, pages 333-340.
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Christina T. Siwak, P. Dwight Tapp, Steven C. Zicker, Heather L. Murphey, Bruce A. Muggenburg, Elizabeth Head, Carl W. Cotman & Norton W. Milgram. (2003) Locomotor activity rhythms in dogs vary with age and cognitive status.. Behavioral Neuroscience 117:4, pages 813-824.
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Christina T. Siwak, Heather L. Murphey, Bruce A. Muggenburg & Norton W. Milgram. (2002) Age-dependent decline in locomotor activity in dogs is environment specific. Physiology & Behavior 75:1-2, pages 65-70.
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B.A. Kinney, C.J. Meliska, R.W. Steger & A. Bartke. (2001) Evidence That Ames Dwarf Mice Age Differently from Their Normal Siblings in Behavioral and Learning and Memory Parameters. Hormones and Behavior 39:4, pages 277-284.
Crossref
Donald K. Ingram. 2001. Functional Neurobiology of Aging. Functional Neurobiology of Aging 373 386 .
R Bergeron, J Bolduc, Y Ramonet, M.C Meunier-Sala?n & S Robert. (2000) Feeding motivation and stereotypies in pregnant sows fed increasing levels of fibre and/or food. Applied Animal Behaviour Science 70:1, pages 27-40.
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Donald K. Ingram & Mathias Jucker. (1999) Developing mouse models of aging: a consideration of strain differences in age-related behavioral and neural parameters?. Neurobiology of Aging 20:2, pages 137-145.
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C.A. Barnes. 1998. Neurobiology of Learning and Memory. Neurobiology of Learning and Memory 247 287 .
Chad H. Groseclose & Lawrence D. Middaugh. (1997) The discrimination and durability of an ethanol cue in young and mid-aged female mice. Alcohol 14:2, pages 191-197.
Crossref
Robert Hitzemann, Yifang Qian, Stephen Kanes, Katherine Dains & Barbara Hitzemann. 1995. 43 94 .
Timothy J. Collier & Paul D. Coleman. (1991) Divergence of biological and chronological aging: Evidence from rodent studies. Neurobiology of Aging 12:6, pages 685-693.
Crossref
C.A. Barnes. 1991. Learning and Memory. Learning and Memory 259 296 .
Jatinder M. Khanna, Harold Kalant, Anita K. Chau & Harish Sharma. (1990) Initial sensitivity, acute tolerance and alcohol consumption in four inbred strains of rats. Psychopharmacology 101:3, pages 390-395.
Crossref
Hanna Michalek, Stefano Fortuna & Annita Pintor. (1989) Age-related differences in brain choline acetyltransferase, cholinesterases and muscarinic receptor sites in two strains of rats. Neurobiology of Aging 10:2, pages 143-148.
Crossref
Lin Lhotellier & Charles Cohen-Salmon. (1989) Genetics and senescence. I. Age-related changes in activity and exploration in three inbred strains of mice. Physiology & Behavior 45:3, pages 491-493.
Crossref
S. Anderson, G. Cornelissen, F. Halberg, P.T. Scarpelli, S. Cagnoni, G. Germano, R. Livi, L. Scarpelli, M. Cagnoni & J.E. Holte. (1989) Age effects upon the harmonic structure of human blood pressure in clinical health. Age effects upon the harmonic structure of human blood pressure in clinical health.
DONALD K. INGRAM. (2006) Motor Performance Variability during Aging in Rodents Assessment of Reliability and Validity of Individual Differences. Annals of the New York Academy of Sciences 515:1, pages 70-96.
Crossref
Eric Le Bourg. 1988. Drosophila as a Model Organism for Ageing Studies. Drosophila as a Model Organism for Ageing Studies 131 139 .
Janet E. Beauvais & Hildegard E. Enesco. (1985) Life span and age-related changes in activity level of the rotifer Asplanchna brightwelli: Influence of curare. Experimental Gerontology 20:6, pages 359-366.
Crossref
M.I. Talan, B.T. Engel & J.R. Whitaker. (1984) Age-related decline in cold tolerance can be retarded by brain stimulation. Physiology & Behavior 33:6, pages 969-973.
Crossref
Eric Le Bourg. (1983) Patterns of movement and ageing in Drosophila melanogaster. Archives of Gerontology and Geriatrics 2:4, pages 299-306.
Crossref
W. Gibson Wood & H. James Armbrecht. (2008) Behavioral Effects of Ethanol in Animals: Age Differences and Age Changes. Alcoholism: Clinical and Experimental Research 6:1, pages 3-12.
Crossref
Donald K. Ingram, Edythe D. London, Mark A. Reynolds, Steven B. Waller & Charles L. Goodrick. (1981) Differential effects of age on motor performance in two mouse strains. Neurobiology of Aging 2:3, pages 221-227.
Crossref
W. Gibson Wood. 1978. The Clinical Psychology of Aging. The Clinical Psychology of Aging 97 113 .
Charles L. Goodrick. 1978. The Genetics of Aging. The Genetics of Aging 403 415 .

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