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Experimental Aging Research
An International Journal Devoted to the Scientific Study of the Aging Process
Volume 24, 1998 - Issue 2
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Original Articles

Serum Cholesterol Levels as a Measure of Frailty in Elderly Patients

Pages 169-179 | Published online: 11 Nov 2010

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Lise Bathum, René Depont Christensen, Lars Engers Pedersen, Palle Lyngsie Pedersen, John Larsen & Jørgen Nexøe. (2013) Association of lipoprotein levels with mortality in subjects aged 50 + without previous diabetes or cardiovascular disease: A population-based register study. Scandinavian Journal of Primary Health Care 31:3, pages 172-180.
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Articles from other publishers (43)

Tomohiko Urano, Tatsuhiko Kuroda & Masataka Shiraki. (2024) Nutritional and inflammation factors associated with current frailty level and effect of co‐morbidities on the progression of frailty. Geriatrics & Gerontology International.
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Wenqing Ni, Yuebin Lv, Xueli Yuan, Yan Zhang, Hongmin Zhang, Yijing Zheng, Xiaoming Shi & Jian Xu. (2024) Associations of Low-density Lipoprotein Cholesterol With All-cause and Cause-specific Mortality in Older Adults in China. The Journal of Clinical Endocrinology & Metabolism.
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Seohyun Kim, Gyuri Kim, So Hyun Cho, Rosa Oh, Ji Yoon Kim, You-Bin Lee, Sang-Man Jin, Kyu Yeon Hur & Jae Hyeon Kim. (2024) Association between total cholesterol levels and all-cause mortality among newly diagnosed patients with cancer. Scientific Reports 14:1.
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Andreas Leiherer, Axel Muendlein, Christoph H Saely, Reijo Laaksonen, Peter Fraunberger & Heinz Drexel. (2024) Ceramides improve cardiovascular risk prediction beyond low-density lipoprotein cholesterol. European Heart Journal Open 4:1.
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Bruna Cristine Chwal, Rodrigo Citton P. dos Reis, Maria Inês Schmidt, Sandhi Maria Barreto, Rosane Harter Griep & Bruce B. Duncan. (2023) Achievement of Treatment Goals and Mortality in Individuals with Diabetes: The ELSA-Brasil Study. Journal of Clinical Medicine 12:24, pages 7663.
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Q. Lei, Z. Xiao, W. Wu, X. Liang, Q. Zhao, Ding Ding & Wei Deng. (2023) The Joint Effect of Body Mass Index and Serum Lipid Levels on Incident Dementia among Community-Dwelling Older Adults. The Journal of nutrition, health and aging 27:11, pages 1118-1126.
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Milly A van der Ploeg, Rosalinde K E Poortvliet, Jonathan M K Bogaerts, Veerle M G T H van der Klei, Ngaire Kerse, Anna Rolleston, Ruth Teh, Louise Robinson, Carol Jagger, Yasumichi Arai, Ryo Shikimoto, Yukiko Abe, Jeanet W Blom, Yvonne M Drewes & Jacobijn Gussekloo. (2023) The Role of a Composite Fitness Score in the Association Between Low-Density Cholesterol and All-Cause Mortality in Older Adults: An Individual Patient Data Meta-Analysis. The Journals of Gerontology: Series A 78:9, pages 1708-1716.
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Shiqi Yuan, Xiaxuan Huang, Wen Ma, Rui Yang, Fengshuo Xu, Didi Han, Tao Huang, MIn Peng, Anding Xu & Jun Lyu. (2023) Associations of HDL-C/LDL-C with myocardial infarction, all-cause mortality, haemorrhagic stroke and ischaemic stroke: a longitudinal study based on 384 093 participants from the UK Biobank. Stroke and Vascular Neurology 8:2, pages 119-126.
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Josefine Freyberg, Eskild M. Landt, Shoaib Afzal, Børge G. Nordestgaard & Morten Dahl. (2023) Low-density lipoprotein cholesterol and risk of COPD: Copenhagen General Population Study. ERJ Open Research 9:2, pages 00496-2022.
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Jing Li, Gang Li, Yajun Zhu, Xingwei Lei, Guihu Chen, Jiachun Zhang & Xiaochuan Sun. (2023) Role of LDL-C level alteration in increased mortality risks in spontaneous intracerebral hemorrhage patients: Systematic review and meta-analysis. Frontiers in Neurology 14.
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Xin Kang, Bin Tian, Zan-Dong Zhao, Bin-Fei Zhang & Ming Zhang. (2023) Evaluation of the Association between Low-Density Lipoprotein (LDL) and All-Cause Mortality in Geriatric Patients with Hip Fractures: A Prospective Cohort Study of 339 Patients. Journal of Personalized Medicine 13:2, pages 345.
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Ella Murphy, Marie Therese Cooney & John W. McEvoy. 2023. Cardiovascular Disease in the Elderly. Cardiovascular Disease in the Elderly 67 138 .
Nida Buawangpong, Chanchanok Aramrat, Kanokporn Pinyopornpanish, Arintaya Phrommintikul, Atiwat Soontornpun, Wichuda Jiraporncharoen, Suphawita Pliannuom & Chaisiri Angkurawaranon. (2022) Risk Prediction Performance of the Thai Cardiovascular Risk Score for Mild Cognitive Impairment in Adults with Metabolic Risk Factors in Thailand. Healthcare 10:10, pages 1959.
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Rui-Xiang Zeng, Jun-Peng Xu, Yong-Jie Kong, Jia-Wei Tan, Li-Heng Guo & Min-Zhou Zhang. (2022) U-Shaped Relationship of Non-HDL Cholesterol With All-Cause and Cardiovascular Mortality in Men Without Statin Therapy. Frontiers in Cardiovascular Medicine 9.
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Le Chang, Xinglin Chen & Cheng Lian. (2022) The association between the non-HDL-cholesterol to HDL-cholesterol ratio and 28-day mortality in sepsis patients: a cohort study. Scientific Reports 12:1.
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Xin Su, Deqiang Zheng, Meiping Wang, Yingting Zuo, Jing Wen, Qi Zhai, Yibo Zhang & Yan He. (2022) Low density lipoprotein cholesterol is associated with increased risk of cardiovascular disease in participants over 70 years old: A prospective cohort study. Nutrition, Metabolism and Cardiovascular Diseases 32:2, pages 447-455.
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Ryuichi Kawamoto, Asuka Kikuchi, Taichi Akase, Daisuke Ninomiya & Teru Kumagi. (2021) Low density lipoprotein cholesterol and all-cause mortality rate: findings from a study on Japanese community-dwelling persons. Lipids in Health and Disease 20:1.
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Camilla Ditlev Lindhardt Johannesen, Anne Langsted, Martin Bødtker Mortensen & Børge Grønne Nordestgaard. (2020) Association between low density lipoprotein and all cause and cause specific mortality in Denmark: prospective cohort study. BMJ, pages m4266.
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Francesco Spannella, Chiara Di Pentima, Federico Giulietti, Silvia Buscarini, Letizia Ristori, Piero Giordano & Riccardo Sarzani. (2020) Prevalence of Subclinical Carotid Atherosclerosis and Role of Cardiovascular Risk Factors in Older Adults: Atherosclerosis and Aging are Not Synonyms. High Blood Pressure & Cardiovascular Prevention 27:3, pages 231-238.
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Nicholas J. W. Rattray, Drupad K. Trivedi, Yun Xu, Tarani Chandola, Caroline H. Johnson, Alan D. Marshall, Krisztina Mekli, Zahra Rattray, Gindo Tampubolon, Bram Vanhoutte, Iain R. White, Frederick C. W. Wu, Neil Pendleton, James Nazroo & Royston Goodacre. (2019) Metabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty. Nature Communications 10:1.
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Itay Bentov, Stephen J. Kaplan, Tam N. Pham & May J. Reed. (2019) Frailty assessment: from clinical to radiological tools. British Journal of Anaesthesia 123:1, pages 37-50.
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Yue‐Bin Lv, Chen Mao, Xiang Gao, Zhao‐Xue Yin, Virginia Byers Kraus, Jin‐Qiu Yuan, Juan Zhang, Jie‐Si Luo, Yi Zeng & Xiao‐Ming Shi. (2019) Triglycerides Paradox Among the Oldest Old: “The Lower the Better?”. Journal of the American Geriatrics Society 67:4, pages 741-748.
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Daisuke Ueshima, Shunji Yoshikawa, Taro Sasaoka, Yu Hatano, Ken Kurihara, Yasuhiro Maejima, Mitsuaki Isobe & Takashi Ashikaga. (2019) The Hypercholesterolemia Paradox in Percutaneous Coronary Intervention: An Analysis of a Multicenter PCI Registry. Internal Medicine 58:3, pages 345-353.
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Judith Charlton, Rathi Ravindrarajah, Shota Hamada, Stephen H Jackson & Martin C Gulliford. (2018) Trajectory of Total Cholesterol in the Last Years of Life Over Age 80 Years: Cohort Study of 99,758 Participants. The Journals of Gerontology: Series A 73:8, pages 1083-1089.
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Shahrul Bahyah Kamaruzzaman. 2018. Geriatric Medicine. Geriatric Medicine 27 41 .
Divya Thekkethala WinovichWilliam T. LongstrethJrJrAlice M. ArnoldRavi VaradhanAdina Zeki Al HazzouriMary CushmanAnne B. NewmanMichelle C. Odden. (2017) Factors Associated With Ischemic Stroke Survival and Recovery in Older Adults. Stroke 48:7, pages 1818-1826.
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Janek Zilinski, Robert Zillmann, Ingrid Becker, Thomas Benzing, Ralf-Joachim Schulz & Gabriele Roehrig. (2014) Prevalence of anemia among elderly inpatients and its association with multidimensional loss of function. Annals of Hematology 93:10, pages 1645-1654.
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Idris Guessous, Jean-Christophe Luthi, Christopher Barrett Bowling, Jean-Marc Theler, Fred Paccaud, Jean-Michel Gaspoz & William McClellan. (2014) Prevalence of Frailty Indicators and Association with Socioeconomic Status in Middle-Aged and Older Adults in a Swiss Region with Universal Health Insurance Coverage: A Population-Based Cross-Sectional Study. Journal of Aging Research 2014, pages 1-8.
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John E. Morley & Gerald Mahon. (2013) Statins and the Nursing Home. Journal of the American Medical Directors Association 14:12, pages 853-854.
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Hwee Soo Jeong, Dong Wook Lee, Ki Heum Park, Yong Kook Lee, Sang Ho Bae, Mi Jin Kang, Min Sung Shim & Chen Hsuen Teong. (2013) Clinical Factors Related to Frailty Estimated by the Korean Frailty Index. Journal of the Korean Geriatrics Society 17:2, pages 71-78.
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John E. Morley. (2011) The Cholesterol Conundrum. Journal of the American Geriatrics Society 59:10, pages 1955-1956.
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Andrea Kenkmann, Gill M Price, Joanne Bolton & Lee Hooper. (2010) Health, wellbeing and nutritional status of older people living in UK care homes: an exploratory evaluation of changes in food and drink provision. BMC Geriatrics 10:1.
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R.E. Pel-Littel, M.J. Schuurmans, M.H. Emmelot-Vonk & H.J.J. Verhaar. (2009) Frailty: Defining and measuring of a concept. The Journal of nutrition, health and aging 13:4, pages 390-394.
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T. Celarier, C. Chol & Régis Gonthier. 2009. La personne âgée fragile. La personne âgée fragile 27 40 .
Tomonori Okamura, Takehito Hayakawa, Atsushi Hozawa, Takashi Kadowaki, Yoshitaka Murakami, Yoshikuni Kita, Robert D. Abbott, Akira Okayama & Hirotsugu Ueshima. (2007) Lower Levels of Serum Albumin and Total Cholesterol Associated with Decline in Activities of Daily Living and Excess Mortality in a 12‐Year Cohort Study of Elderly Japanese. Journal of the American Geriatrics Society 56:3, pages 529-535.
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Kenji Toba. (2008) Evidence Based Nursing in Long-term Care介護予防のエビデンス. Nihon Naika Gakkai Zasshi 97:10, pages 2566-2574.
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Penelope K. Elias, Merrill F. Elias, Ralph B. D’Agostino, Lisa M. Sullivan & Philip A. Wolf. (2005) Serum Cholesterol and Cognitive Performance in the Framingham Heart Study. Psychosomatic Medicine 67:1, pages 24-30.
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Rashmi R. Shah. (2004) Drug development and use in the elderly: search for the right dose and dosing regimen. British Journal of Clinical Pharmacology 58:5, pages 452-469.
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L. Repetto, A. Venturino, L. Fratino, D. Serraino, G. Troisi, W. Gianni & M. Pietropaolo. (2003) Geriatric oncology. European Journal of Cancer 39:7, pages 870-880.
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J. E. Morley, H. M. Perry & D. K. Miller. (2002) Editorial: Something About Frailty. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 57:11, pages M698-M704.
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ML Corrêa Leite, A Nicolosi, S Cristina, WA Hauser & G Nappi. (2001) Nutrition and cognitive deficit in the elderly: a population study. European Journal of Clinical Nutrition 55:12, pages 1053-1058.
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Valérie Deschamps, Pascale Barberger-Gateau, Evelyne Peuchant & Jean Marc Orgogozo. (2001) Nutritional Factors in Cerebral Aging and Dementia: Epidemiological Arguments for a Role of Oxidative Stress. Neuroepidemiology 20:1, pages 7-15.
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Kenneth Rockwood, David B. Hogan & Chris MacKnight. (2000) Conceptualisation and Measurement of Frailty in Elderly People. Drugs & Aging 17:4, pages 295-302.
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