Publication Cover
Hemoglobin
international journal for hemoglobin research
Volume 30, 2006 - Issue 2
174
Views
59
CrossRef citations to date
0
Altmetric
PROCEEDINGS 15th ICOCTaiwan, April 2005

Low Serum Ferritin Levels are Misleading for Detecting Cardiac Iron Overload and Increase the Risk of Cardiomyopathy in Thalassemia Patients. The Importance of Cardiac Iron Overload Monitoring Using Magnetic Resonance Imaging T2 and T2*

, , &
Pages 219-227 | Published online: 07 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (14)

Chin F. Ngim, Mei Y. Lee, Norliza Othman, Soo M. Lim, Chen S. Ng & Amutha Ramadas. (2019) Prevalence and Risk Factors for Cardiac and Liver Iron Overload in Adults with Thalassemia in Malaysia. Hemoglobin 43:2, pages 95-100.
Read now
Natthaphat Siri-Angkul, Siriporn C Chattipakorn & Nipon Chattipakorn. (2018) Diagnosis and treatment of cardiac iron overload in transfusion-dependent thalassemia patients. Expert Review of Hematology 11:6, pages 471-479.
Read now
Ampaiwan Chuansumrit, Jiraporn Laothamathat, Nongnuch Sirachainan, Witaya Sungkarat, Pakawan Wongwerawattanakoon & Patrapop Kumkrua. (2016) Correlation between liver iron concentration determined by magnetic resonance imaging and serum ferritin in adolescents with thalassaemia disease. Paediatrics and International Child Health 36:3, pages 203-208.
Read now
Efthymia Vlachaki, Alexandra Agapidou, Georgios Spanos, Philippos Klonizakis, Evaggelia Vetsiou, Melahrini Mavroudi & Panagiota Boura. (2015) Five Years of Deferasirox Therapy for Cardiac Iron in β-Thalassemia Major. Hemoglobin 39:5, pages 299-304.
Read now
Nut Koonrungsesomboon, Adisak Tantiworawit, Arintaya Phrommintikul, Suwit Saekho, Somdet Srichairattanakool & Nipon Chattipakorn. (2015) Heart Rate Variability for Early Detection of Iron Overload Cardiomyopathy in β-Thalassemia Patients. Hemoglobin 39:4, pages 281-286.
Read now
El-Sayed H. Ibrahim, Fauzia N. Rana, Kevin R. Johnson & Richard D. White. (2012) Assessment of Cardiac Iron Deposition in Sickle Cell Disease Using 3.0 Tesla Cardiovascular Magnetic Resonance. Hemoglobin 36:4, pages 343-361.
Read now
Athanassios Aessopos, Maria Kati & Maria Tsironi. (2008) Congestive Heart Failure and Treatment in Thalassemia Major. Hemoglobin 32:1-2, pages 63-73.
Read now
Maria Tsironi, George Assimakopoulos, Katerina Polonofi, Kalliopi Rigaki & Athanassios Aessopos. (2008) Effects of Combined Deferiprone and Deferoxamine Chelation Therapy on Iron Load Indices in β-Thalassemia. Hemoglobin 32:1-2, pages 29-34.
Read now

Articles from other publishers (45)

George J. Kontoghiorghes. (2023) Iron Load Toxicity in Medicine: From Molecular and Cellular Aspects to Clinical Implications. International Journal of Molecular Sciences 24:16, pages 12928.
Crossref
Ahmed Karam Eldaly & Ayman M. Khalifa. (2023) A general framework for hepatic iron overload quantification using MRI. Digital Signal Processing 137, pages 104048.
Crossref
Deidra Ansah, Nazia Husain, Alexander Ruh, Haben Berhane, Anthony Smith, Alexis Thompson, Andrew De Freitas, Cynthia K. Rigsby & Joshua D. Robinson. (2023) Cardiac Magnetic Resonance Strain in Beta Thalassemia Major Correlates with Cardiac Iron Overload. Children 10:2, pages 271.
Crossref
Jason K. Higa, Nicholas K. Kawasaki & Takashi Matsui. 2023. Ferroptosis in Health and Disease. Ferroptosis in Health and Disease 149 193 .
Mufarreh Asmari, Muhammad Waqas, Adel Ehab Ibrahim, Sobia Ahsan Halim, Ajmal Khan, Ahmed Al-Harrasi, Hermann Wätzig & Sami El Deeb. (2022) Microscale Thermophoresis and Molecular Modelling to Explore the Chelating Drug Transportation in the Milk to Infant. Molecules 27:14, pages 4604.
Crossref
Guanwu Li, Zheng Xu, Yi Wang, Lei Jiang, Shixin Chang, Wei Yuan & Yongming Dai. (2022) Association of Serum Ferritin With Marrow Iron Concentration Using a Three-Dimension Fat Analysis & Calculation Technique Sequence in Postmenopausal Women. Journal of Computer Assisted Tomography 46:3, pages 464-469.
Crossref
Firoozeh Abtahi, Alireza Abdi, Saideh Jamshidi, Mehran Karimi, Mohammad Ali Babaei-Beigi & Armin Attar. (2019) Global longitudinal strain as an Indicator of cardiac Iron overload in thalassemia patients. Cardiovascular Ultrasound 17:1.
Crossref
Aziz Eghbali, Atefeh Khalilpour, Hassan Taherahmadi & Bahador Bagheri. (2019) Pantoprazole reduces serum ferritin in patients with thalassemia major and intermedia: A randomized, controlled study. Therapies 74:5, pages 507-512.
Crossref
Azza Ahmed, Amani Baldo, Hind Margani, Ahmed Fatah, Ibrahim Idris & Isam Salih. 2019. World Congress on Medical Physics and Biomedical Engineering 2018. World Congress on Medical Physics and Biomedical Engineering 2018 57 62 .
Jason K. Higa, Nicholas K. Kawasaki & Takashi Matsui. 2019. Ferroptosis in Health and Disease. Ferroptosis in Health and Disease 147 172 .
John Chapin & Patricia J. Giardina. 2018. Hematology. Hematology 546 570.e10 .
Stefan Ropele & Christian Langkammer. (2016) Iron quantification with susceptibility. NMR in Biomedicine 30:4.
Crossref
Monia Ouederni, Monia Ben Khaled, Fethi Mellouli, Elhem Ben Fraj, Nawel Dhouib, Ismehen Ben Yakoub, Selem Abbes, Nejla Mnif & Mohamed Bejaoui. (2016) Myocardial and liver iron overload, assessed using T2* magnetic resonance imaging with an excel spreadsheet for post processing in Tunisian thalassemia major patients. Annals of Hematology 96:1, pages 133-139.
Crossref
El-Sayed H. Ibrahim, Ayman M. Khalifa & Ahmed K. Eldaly. (2016) Influence of the analysis technique on estimating hepatic iron content using MRI. Journal of Magnetic Resonance Imaging 44:6, pages 1448-1455.
Crossref
Tevfik Guzelbey, Bengi Gurses, Erman Ozturk, Olcay Ozveren, Aysegul Sarsilmaz & Ebru Karasu. (2016) Evaluation of Iron Deposition in the Adrenal Glands of β Thalassemia Major Patients Using 3-Tesla MRI. Iranian Journal of Radiology 13:3.
Crossref
Galila M Mokhtar, Wafaa E Ibrahim, Nancy S Elbarbary, Randa M Matter, Ahmed S Ibrahim & Safa M Sayed. (2023) Pancreatic Functions in Adolescents with Beta Thalassemia Major Could Predict Cardiac and Hepatic Iron Loading: Relation to T2-Star (T2*) Magnetic Resonance Imaging. Journal of Investigative Medicine 64:3, pages 771-781.
Crossref
Christina N Kontoghiorghe & George J Kontoghiorghes. (2016) New developments and controversies in iron metabolism and iron chelation therapy. World Journal of Methodology 6:1, pages 1.
Crossref
Kazusa Ishii & Neal S. Young. (2015) Anemia of Central Origin. Seminars in Hematology 52:4, pages 321-338.
Crossref
Lucía Gutiérrez, Michael J. House, Nisha Vasavda, Emma Drašar, Isabel Gonzalez-Gascon y Marin, Austin G. Kulasekararaj, Tim G. St Pierre & Swee L. Thein. (2015) Tissue Iron Distribution Assessed by MRI in Patients with Iron Loading Anemias. PLOS ONE 10:9, pages e0139220.
Crossref
Anna Perrone, Luisa Tesoriere, Anna Maria Pintaudi, Alessandro Attanzio, Paolo Rigano, Aurelio Maggio & Maria Antonietta Livrea. (2014) Raman Spectroscopy Technology to Monitor the Carotenoids in Skin of Thalassemia Patients: A Novel Non-Invasive Tool Relating Oxidative Stress with Iron Burden. Thalassemia Reports 4:2, pages 1967.
Crossref
El-Sayed H. Ibrahim & Andrew W. Bowman. (2014) Characterization of myocardial iron overload by dual-energy computed tomography compared to T2 MRI. A phantom study. Characterization of myocardial iron overload by dual-energy computed tomography compared to T2 MRI. A phantom study.
El-Sayed H. Ibrahim, Ayman M. Khalifa & Ahmed K. Eldaly. (2014) The Influence of the analysis technique on estimating liver iron overload using magnetic resonance imaging T2 quantification. The Influence of the analysis technique on estimating liver iron overload using magnetic resonance imaging T2 quantification.
Susan M. Carson & Marie B. Martin. (2014) Effective Iron Chelation Practice for Patients With β-Thalassemia Major. Clinical Journal of Oncology Nursing 18:1, pages 102-111.
Crossref
El-Sayed H. Ibrahim, Ayman M. Khalifa, Ahmed K. Eldaly & Andrew W. Bowman. (2014) The effects of the analysis technique on hepatic iron evaluation using T2 mapping with magnetic resonance imaging. The effects of the analysis technique on hepatic iron evaluation using T2 mapping with magnetic resonance imaging.
El-Sayed H. Ibrahim, Andrew W. Bowman & Ayman M. Khalifa. (2014) Dual-energy computed tomography versus magnetic resonance imaging for the assessment of iron overload. Dual-energy computed tomography versus magnetic resonance imaging for the assessment of iron overload.
Annita Kolnagou. (2014) Transition of Thalassaemia and Friedreich ataxia from fatal to chronic diseases. World Journal of Methodology 4:4, pages 197.
Crossref
Carlo Liguori, Francesca Pitocco, Ilenia Di Giampietro, Aldo Eros de Vivo, Emiliano Schena, Paolo Cianciulli & Bruno Beomonte Zobel. (2013) Relationship between myocardial T2* values and cardiac volumetric and functional parameters in β-thalassemia patients evaluated by cardiac magnetic resonance in association with serum ferritin levels. European Journal of Radiology 82:9, pages e441-e447.
Crossref
M. ‐Y. Lu, S. S. F. Peng, H. ‐H. Chang, Y. ‐L. Yang, C. ‐A. Chen, S. ‐T. Jou, D. ‐T. Lin & K. ‐H. Lin. (2013) Cardiac iron measurement and iron chelation therapy in patients with β thalassaemia major: experience from Taiwan. Transfusion Medicine 23:2, pages 100-107.
Crossref
Jon Detterich, Leila Noetzli, Fred Dorey, Yaniv Bar‐Cohen, Paul Harmatz, Thomas Coates & John Wood. (2011) Electrocardiographic consequences of cardiac iron overload in thalassemia major. American Journal of Hematology 87:2, pages 139-144.
Crossref
Reijane Alves de Assis, Fernando Uliana Kay, Laércio Alberto Rosemberg, Alexandre Henrique C. Parma, Cesar Higa Nomura, Sandra Regina Loggetto, Aderson da Silva Araujo, Antonio Fabron Junior, Mônica Pinheiro de Almeida Veríssimo, Giorgio Roberto Baldanzi, Merula A. Steagal, Claudia Angela Galleni Di Sessa Velloso, Breno Pannia Espósito, Sandra Saemi Nakashima, Michelli da Silva Diniz, Fernando Tricta, Ronaldo Hueb Baroni, Marcelo Buarque de Gusmão Funari, John C. Wood, Andreza Alice Feitosa Ribeiro & Nelson Hamerschlak. (2011) Iron overload in Brazilian thalassemic patients. Einstein (São Paulo) 9:2, pages 165-172.
Crossref
Adrianna Vlachos & Ellen Muir. (2010) How I treat Diamond-Blackfan anemia. Blood 116:19, pages 3715-3723.
Crossref
Annita Kolnagou, Marios Kleanthous & George J. Kontoghiorghes. (2010) Reduction of body iron stores to normal range levels in thalassaemia by using a deferiprone/deferoxamine combination and their maintenance thereafter by deferiprone monotherapy. European Journal of Haematology 85:5, pages 430-438.
Crossref
L. R. ZACHARSKI, L. MCKERNAN, M. E. METZGER, M. G. MALONE, V. SAMNOTRA, A. BHARGAVA, P. R. STEINER, C. A. RAUWERDINK, D. L. ORNSTEIN & C. J. CORNELL. (2010) Remission of paroxysmal atrial fibrillation with iron reduction in haemophilia A. Haemophilia 16:5, pages 726-730.
Crossref
Anil Pathare, Ali Taher & Shahina Daar. (2009) Deferasirox (Exjade®) significantly improves cardiac T2* in heavily iron-overloaded patients with β-thalassemia major. Annals of Hematology 89:4, pages 405-409.
Crossref
Stavros Kounas & Perry M Elliott. 2009. Evidence‐Based Cardiology. Evidence‐Based Cardiology 808 822 .
Olympia Papakonstantinou, Efthymia Alexopoulou, Nikos Economopoulos, Odysseas Benekos, Antonis Kattamis, Stavroula Kostaridou, Vasilis Ladis, Efstathios Efstathopoulos, Athanassios Gouliamos & Nikolaos L. Kelekis. (2009) Assessment of iron distribution between liver, spleen, pancreas, bone marrow, and myocardium by means of R2 relaxometry with MRI in patients with β‐thalassemia major. Journal of Magnetic Resonance Imaging 29:4, pages 853-859.
Crossref
R.H.B. Meyboom. 2009. 399 407 .
Daniel T. Boll & Elmar M. Merkle. 2009. CT and MRI of the Whole Body. CT and MRI of the Whole Body 1455 1499 .
Leila J. NoetzliSusan M. Carson, Anne S. Nord, Thomas D. Coates & John C. Wood. (2008) Longitudinal analysis of heart and liver iron in thalassemia major. Blood 112:7, pages 2973-2978.
Crossref
Manju Mamtani & Hemant Kulkarni. (2008) Influence of iron chelators on myocardial iron and cardiac function in transfusion‐dependent thalassaemia: a systematic review and meta‐analysis. British Journal of Haematology 141:6, pages 882-890.
Crossref
Mark A Tanner, Renzo Galanello, Carlo Dessi, Gillian C Smith, Mark A Westwood, Annalisa Agus, Martina Pibiri, Sunil V Nair, J Malcolm Walker & Dudley J Pennell. (2008) Combined chelation therapy in thalassemia major for the treatment of severe myocardial siderosis with left ventricular dysfunction. Journal of Cardiovascular Magnetic Resonance 10:1, pages 12.
Crossref
Lina B. Karam, Deborah Disco, Sherron M. Jackson, David Lewin, Virgil Mckie, Robert D. Baker, Susan S. Baker, Joseph H. Laver, Paul J. Nietert & Miguel R. Abboud. (2007) Liver biopsy results in patients with sickle cell disease on chronic transfusions: Poor correlation with ferritin levels. Pediatric Blood & Cancer 50:1, pages 62-65.
Crossref
Athanassios Aessopos, Maria Kati, Dimitrios Farmakis, Ekaterini Polonifi, Spyros Deftereos & Maria Tsironi. (2007) Intensive Chelation Therapy in β-Thalassemia and Possible Adverse Cardiac Effects of Desferrioxamine. International Journal of Hematology 86:3, pages 212-215.
Crossref
Athanassios Aessopos, Spyros Deftereos, Maria Tsironi, Fotios Karabatsos, Jacqueline Yousef, Christina Fragodimitri, Antonia Hatziliami & Markissia Karagiorga. (2007) Predictive echo-Doppler indices of left ventricular impairment in B-thalassemic patients. Annals of Hematology 86:6, pages 429-434.
Crossref
John C Wood. (2007) Magnetic resonance imaging measurement of iron overload. Current Opinion in Hematology 14:3, pages 183-190.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.