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Research Article

In Vitro and In Vivo Evaluation of Two Extended Release Preparations of Combination Metformin and Glipizide

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Pages 677-685 | Published online: 26 Sep 2008

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Napoleon-Nikolaos Vrettos, Peng Wang, Yan Zhou, Clive J. Roberts, Jinyi Xu, Hong Yao & Zheying Zhu. (2021) In vitro and in vivo evaluation of a sustained-release once-a-day formulation of the novel antihypertensive drug MT-1207. Pharmaceutical Development and Technology 26:3, pages 349-361.
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Song Gao, Yanjun Chen, Rongfeng Hu, Wenjie Lu, Lingfei Yu, Jiayi Chen, Songlin Liu, Yuxing Guo, Qiang Shen, Bin Wang & Wenyou Fang. (2020) Visualized analysis and evaluation of simultaneous controlled release of metformin hydrochloride and gliclazide from sandwiched osmotic pump capsule. Drug Development and Industrial Pharmacy 46:11, pages 1776-1786.
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Hao Pan, Hengpan Jing, Xinggang Yang, Weisan Pan & Tianbao Chen. (2017) Synchronized and controlled release of metformin hydrochloride/glipizide from elementary osmotic delivery. Drug Development and Industrial Pharmacy 43:5, pages 780-788.
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Shiqing Zhao, Fanglin Yu, Nan Liu, Zhong Di, Kun Yan, Yan Liu, Ying Li, Hui Zhang, Yang Yang, Zhenbo Yang, Zhiping Li & Xingguo Mei. (2016) Synchronous delivery of felodipine and metoprolol tartrate using monolithic osmotic pump technology. Drug Development and Industrial Pharmacy 42:11, pages 1723-1731.
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Chien Nguyen, J. Mark Christensen & James W. Ayres. (2014) Compression of coated drug beads for sustained release tablet of glipizide: formulation, and dissolution. Pharmaceutical Development and Technology 19:1, pages 10-20.
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R.B. Patel, G.N. Patel, H.R. Patel & M.M. Patel*. (2011) Inlay osmotic pump tablets containing metformin and glipizide. Drug Development and Industrial Pharmacy 37:10, pages 1244-1252.
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Li-Fang Yin, Shi-Jing Huang, Shu-Guang Jiang, Chun-Jie Zhao, Zhi-Qiang Pei & Qiang Zhang. (2011) In vitro and in vivo evaluation of levofloxacin sustained-release capsules. Drug Development and Industrial Pharmacy 37:1, pages 33-40.
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Lanlan Wei, Jie Li, Liangran Guo, Shufang Nie, Weisan Pan, Peinan Sun & Hui Liu. (2007) Investigations of a Novel Self-Emulsifying Osmotic Pump Tablet Containing Carvedilol. Drug Development and Industrial Pharmacy 33:9, pages 990-998.
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Articles from other publishers (24)

Jeovani González-Barbosa, Adrián Ricardo Hipólito-Nájera, Rodolfo Gómez-Balderas, Norma Rodríguez-Laguna & Rosario Moya-Hernández. (2024) Metformin, Chlorpropamide, and Glibenclamide: Interactions with Metal Ions and Cyclodextrins. Mini-Reviews in Organic Chemistry 21:3, pages 272-294.
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Sayali A. Nangare, Asif H. Ali, Kakasaheb R. Mahadik & Sharvil S. Patil. (2023) Fabrication, optimization and characterization of an osmotic push-pull drug delivery system for paliperidone. Journal of Taibah University Medical Sciences 18:6, pages 1511-1518.
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Ravisinh Solanki, Pooja Wadhwana, Ravi Patel, Bhavinkumar Gayakvad, Charmy Kothari & Chhaganbhai Patel. (2023) Analytical Method Capable of Quantifying Eight Nitrosamine Impurities from Five Different Commercially Available Metformin Formulations with Glipizide, Glibenclamide, Gliclazide, Evogliptin, and Glimepiride by Ultra High Performance Liquid Chromatography Tripple Quadrupole Mass Spectrometry. Journal of Pharmaceutical Sciences 112:5, pages 1268-1276.
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Ruedeekorn Wiwattanapatapee, Kalayamas Klabklay, Nontawat Raksajit, Worrawee Siripruekpong, Nattawut Leelakanok & Arpa Petchsomrit. (2023) The development of an in-situ biopolymer-based floating gel for the oral delivery of metformin hydrochloride. Heliyon 9:4, pages e14796.
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Urba Afnan, Kashma Sharma, Rakesh Sehgal & Vijay Kumar. 2023. Polymeric Nanosystems. Polymeric Nanosystems 333 365 .
Alok Ranjan & Prateek K. Jha. (2021) Recent Advances in Dissolution Testing and Their Use to Improve In Vitro–In Vivo Correlations in Oral Drug Formulations. Journal of Pharmaceutical Innovation 17:3, pages 1011-1026.
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Sameer Joshi, Rajnish Sahu, Vida A. Dennis & Shree R. Singh. (2021) Nanofiller-Enhanced Soft Non-Gelatin Alginate Capsules for Modified Drug Delivery. Pharmaceuticals 14:4, pages 355.
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Xiangjiang Nie, Bin Wang, Rongfeng Hu, Wenjie Lu, Jiayi Chen, Songlin Liu, Dong Jin, Chaojie Sun, Song Gao, Yuxing Guo, Wenyou Fang & Haiping Hao. (2020) Development and Evaluation of Controlled and Simultaneous Release of Compound Danshen Based on a Novel Colon-Specific Osmotic Pump Capsule. AAPS PharmSciTech 21:2.
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Zara Khizer, Muhammad R. Akram, Rai M. Sarfraz, Jorabar Singh Nirwan, Samia Farhaj, Maria Yousaf, Tariq Hussain, Shan Lou, Peter Timmins, Barbara R. Conway & Muhammad Usman Ghori. (2019) Plasticiser-Free 3D Printed Hydrophilic Matrices: Quantitative 3D Surface Texture, Mechanical, Swelling, Erosion, Drug Release and Pharmacokinetic Studies. Polymers 11:7, pages 1095.
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Boddu Prasanthi, Karamchety Surya Kameswari Shilpa, Mudili Nagabhushana Rao & Ponukumati Uma Devi. (2016) Design and evaluation of bilayer tablets of metformin hydrochloride and pioglitazone hydrochloride as combination drug therapy. Journal of Pharmaceutical Investigation 47:6, pages 497-505.
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Rania Hamed, Ali Al-Samydai, Tamadur Al Baraghthi, Ola Tarawneh & Suhair Sunoqrot. (2017) Influence of HPMC K100LV and Compritol® HD5 ATO on Drug Release and Rheological Behavior of HPMC K4M Matrix Tablets. Journal of Pharmaceutical Innovation 12:1, pages 62-75.
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M. O. Adedokun,M. A. Momoh,F. C. Kenechukwu,O. N. C. Umeh,C. M. J Okpalanedu,K. C. Ofokansi,. (2014) Novel carrier system for enhancing oral delivery of metformin. African Journal of Biotechnology 13:50, pages 4568-4576.
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Amolkumar B. Lokhande, Satyendra Mishra, Ravindra D. Kulkarni & Jitendra B. Naik. (2013) Influence of different viscosity grade ethylcellulose polymers on encapsulation and in?vitro release study of drug loaded nanoparticles. Journal of Pharmacy Research 7:5, pages 414-420.
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Zhi-hong Zhang & Wei-san Pan. 2013. Formulation Tools for Pharmaceutical Development. Formulation Tools for Pharmaceutical Development 73 108 .
Young-Lae Lee, Min-Soo Kim, Myung-Yong Park & Kun Han. (2012) Quality by design: understanding the formulation variables and optimization of metformin hydrochloride 750 mg sustained release tablet by Box–Behnken design. Journal of Pharmaceutical Investigation 42:4, pages 213-220.
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Ling Zhao, Yumeng Wei, Yong Mei, Li Yang, Yuan You, Xufeng Yang & Yanhong Jiang. (2012) Preparation and <i>in Vitro</i> Drug Release Evaluation of Once-Daily Metformin Hydrochloride Sustained-Release Tablets. Pharmacology & Pharmacy 03:04, pages 468-473.
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Kwang-Hee Shin, Sung Eun Kim, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang, Sang-Goo Shin & Kyung-Sang Yu. (2011) Pharmacokinetic Comparison of a New Sustained-Release Formulation of Glimepiride/Metformin 1/500 mg Combination Tablet and a Sustained-Release Formulation of Glimepiride/Metformin 2/500 mg Combination Tablet in Healthy Korean Male Volunteers: A Randomized, 2-Sequence, 2-Period, 2-Treatment Crossover Study. Clinical Therapeutics 33:11, pages 1809-1818.
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Zhi-hong Zhang, Hong-ye Dong, Bo Peng, Hong-fei Liu, Chun-lei Li, Min Liang & Wei-san Pan. (2011) Design of an expert system for the development and formulation of push?pull osmotic pump tablets containing poorly water-soluble drugs. International Journal of Pharmaceutics 410:1-2, pages 41-47.
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Bhavesh Barot, Punit Parejiya, Tushar Patel, Rajesh Parikh & Mukesh Gohel. (2010) Development of directly compressible metformin hydrochloride by the spray-drying technique. Acta Pharmaceutica 60:2, pages 165-175.
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Vincent Malaterre, Joerg Ogorka, Nicoletta Loggia & Robert Gurny. (2009) Oral osmotically driven systems: 30 years of development and clinical use. European Journal of Pharmaceutics and Biopharmaceutics 73:3, pages 311-323.
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N. Fotaki, A. Aivaliotis, J. Butler, J. Dressman, M. Fischbach, J. Hempenstall, S. Klein & C. Reppas. (2009) A comparative study of different release apparatus in generating in vitro–in vivo correlations for extended release formulations. European Journal of Pharmaceutics and Biopharmaceutics 73:1, pages 115-120.
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Zhi-hong Zhang, Wei Li, Shu-fang Nie, Xin Tang, Bo Peng, Lei Tian & Wei-san Pan. (2009) Overcome side identification in PPOP by making orifices on both layers. International Journal of Pharmaceutics 371:1-2, pages 1-7.
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X. Yang, H. Wu, S. Nie, T. Yan, L. Hong & W. Pan. (2008) A new type of double-layered osmotic pump controlled release tablets of bezafibrate with poor water solubility and large dosage. Journal of Drug Delivery Science and Technology 18:4, pages 273-277.
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Uttam MANDAL, Veeran GOWDA, Animesh GHOSH, Senthamil SELVAN, Sam SOLOMON & Tapan Kumar PAL. (2007) Formulation and Optimization of Sustained Release Matrix Tablet of Metformin HCl 500 mg Using Response Surface Methodology. YAKUGAKU ZASSHI 127:8, pages 1281-1290.
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