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Drug Development and Industrial Pharmacy Volume 33, 2007 - Issue 7
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Research Article

Part II: Bioavailability in Beagle Dogs of Nimodipine Solid Dispersions Prepared by Hot-Melt Extrusion

Xin Zheng Department of Pharmaceutics, Shenyang Pharmaceutical University, Shenyang, Liaoning, P.R. China
,
Rui Yang Department of Pharmaceutics, Shenyang Pharmaceutical University, Shenyang, Liaoning, P.R. China
,
Yu Zhang Department of Pharmaceutics, Shenyang Pharmaceutical University, Shenyang, Liaoning, P.R. China
,
Zhijun Wang Department of Pharmaceutics, Shenyang Pharmaceutical University, Shenyang, Liaoning, P.R. China
,
Xing Tang Department of Pharmaceutics, Shenyang Pharmaceutical University, Shenyang, Liaoning, P.R. China
&
Liangyuan Zheng Department of Pharmaceutics, Shenyang Pharmaceutical University, Shenyang, Liaoning, P.R. China
Pages 783-789 | Published online: 26 Sep 2008

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Jian Hou, E. Sun, Zhen-Hai Zhang, Jing Wang, Lei Yang, Li Cui, Zhong-Cheng Ke, Xiao-Bin Tan, Xiao-Bin Jia & Huixia Lv. (2017) Improved oral absorption and anti-lung cancer activity of paclitaxel-loaded mixed micelles. Drug Delivery 24:1, pages 261-269.
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Bart Claeys, Reinout Vandeputte, Bruno G. De Geest, Jean Paul Remon & Chris Vervaet. (2016) pH-independent immediate release polymethacrylate formulations – an observational study. Drug Development and Industrial Pharmacy 42:4, pages 578-583.
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Mohd Aftab Alam, Raisuddin Ali, Fahad Ibrahim Al-Jenoobi & Abdullah M Al-Mohizea. (2012) Solid dispersions: a strategy for poorly aqueous soluble drugs and technology updates. Expert Opinion on Drug Delivery 9:11, pages 1419-1440.
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Jia Feng, Lishuang Xu, Renchao Gao, Yanfei Luo & Xing Tang. (2012) Evaluation of polymer carriers with regard to the bioavailability enhancement of bifendate solid dispersions prepared by hot-melt extrusion. Drug Development and Industrial Pharmacy 38:6, pages 735-743.
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Parinda Srinarong, Bao T. Pham, Maru Holen, Afke van der Plas, Reinout C.A. Schellekens, Wouter L.J. Hinrichs & Henderik W. Frijlink. (2012) Preparation and physicochemical evaluation of a new tacrolimus tablet formulation for sublingual administration. Drug Development and Industrial Pharmacy 38:4, pages 490-500.
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L.S. Ranzani, J. Font, F. Galimany, A. Santanach, A.M. Gomez-Gomar, G. Casadevall & A. Gryczke. (2011) Enhanced in vivo absorption of CB-1 antagonist in rats via solid solutions prepared by hot-melt extrusion. Drug Development and Industrial Pharmacy 37:6, pages 694-701.
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James C. DiNunzio, Justin R. Hughey, Chris Brough, Dave A. Miller, Robert O. Williams III & James W. McGinity. (2010) Production of advanced solid dispersions for enhanced bioavailability of itraconazole using KinetiSol® Dispersing. Drug Development and Industrial Pharmacy 36:9, pages 1064-1078.
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Mori Dhaval, Shweta Sharma, Kiran Dudhat & Jayant Chavda. (2020) Twin-Screw Extruder in Pharmaceutical Industry: History, Working Principle, Applications, and Marketed Products: an In-depth Review. Journal of Pharmaceutical Innovation 17:2, pages 294-318.
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Kofi Oti Boakye‐Yiadom, Samuel Kesse, Md Aquib, Mensura Sied Filli, Muhammad Asim Farooq & Bo Wang. (2020) Solid dispersion systems engineered from hydroxypropyl‐β‐cyclodextrin and water‐soluble polymers for enhanced oral bioavailability of nimodipine . Polymers for Advanced Technologies.
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Md Obyedul Kalam Azad, Wie Soo Kang, Jung Dae Lim & Cheol Ho Park. (2019) Bio- Fortification of Angelica gigas Nakai Nano-Powder Using Bio-Polymer by Hot Melt Extrusion to Enhance the Bioaccessibility and Functionality of Nutraceutical Compounds. Pharmaceuticals 13:1, pages 3.
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Blake Herren, Preston Larson, Mrinal Saha & Yingtao Liu. (2019) Enhanced Electrical Conductivity of Carbon Nanotube-Based Elastomer Nanocomposites Prepared by Microwave Curing. Polymers 11:7, pages 1212.
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T.R. Hörmann, N. Jäger, A. Funke, R.-K. Mürb, J.G. Khinast & A. Paudel. (2018) Formulation performance and processability window for manufacturing a dual-polymer amorphous solid dispersion via hot-melt extrusion and strand pelletization. International Journal of Pharmaceutics 553:1-2, pages 408-421.
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Marzena Rams-Baron, Renata Jachowicz, Elena Boldyreva, Deliang Zhou, Witold Jamroz & Marian PaluchMarzena Rams-Baron, Renata Jachowicz, Elena Boldyreva, Deliang Zhou, Witold Jamroz & Marian Paluch. 2018. Amorphous Drugs. Amorphous Drugs 41 68 .
James C. DiNunzio & James W. McGinity. 2017. Concise Encyclopedia of Biomedical Polymers and Polymeric Biomaterials. Concise Encyclopedia of Biomedical Polymers and Polymeric Biomaterials 451 475 .
Amitava Mitra, Li Li, Patrick Marsac, Brian Marks, Zhen Liu & Chad Brown. (2016) Impact of polymer type on bioperformance and physical stability of hot melt extruded formulations of a poorly water soluble drug. International Journal of Pharmaceutics 505:1-2, pages 107-114.
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Robert Schmitt, true Rogers, William Porter, Oliver Petermann & Britta Huebner-Keese. 2015. Handbook of Encapsulation and Controlled Release. Handbook of Encapsulation and Controlled Release 517 534 .
Samuel O. Kyeremateng, Marieke Pudlas & Gerd H. Woehrle. (2014) A Fast and Reliable Empirical Approach for Estimating Solubility of Crystalline Drugs in Polymers for Hot Melt Extrusion Formulations. Journal of Pharmaceutical Sciences 103:9, pages 2847-2858.
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Yuangang Zu, Na Li, Xiuhua Zhao, Yong Li, Yulong Ge, Weiguo Wang, Kunlun Wang & Ying Liu. (2014) In vitro dissolution enhancement of micronized l-nimodipine by antisolvent re-crystallization from its crystal form H. International Journal of Pharmaceutics 464:1-2, pages 1-9.
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Justin M. Keen, James W. McGinity & Robert O. Williams III. (2013) Enhancing bioavailability through thermal processing. International Journal of Pharmaceutics 450:1-2, pages 185-196.
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Mark Hall & Michael Read. 2012. Hot‐Melt Extrusion: Pharmaceutical Applications. Hot‐Melt Extrusion: Pharmaceutical Applications 145 175 .
Sandra Guns & Guy Van den Mooter. 2012. Hot‐Melt Extrusion: Pharmaceutical Applications. Hot‐Melt Extrusion: Pharmaceutical Applications 223 237 .
Ann Newman, Gregory Knipp & George Zografi. (2012) Assessing the performance of amorphous solid dispersions. Journal of Pharmaceutical Sciences 101:4, pages 1355-1377.
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Yohei Kawabata, Koichi Wada, Manabu Nakatani, Shizuo Yamada & Satomi Onoue. (2011) Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: Basic approaches and practical applications. International Journal of Pharmaceutics 420:1, pages 1-10.
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Fu Jijun, Zhang Lili, Guan Tingting, Tang Xing & He Haibing. (2010) Stable nimodipine tablets with high bioavailability containing NM-SD prepared by hot-melt extrusion. Powder Technology 204:2-3, pages 214-221.
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Raghu Cavatur, N Vemuri & Raj Suryanarayanan. 2008. Pharmaceutical Dosage Forms - Tablets. Pharmaceutical Dosage Forms - Tablets 465 483 .
Raghu Cavatur, N Vemuri & Raj Suryanarayanan. 2008. Pharmaceutical Dosage Forms - Tablets, Third Edition. Pharmaceutical Dosage Forms - Tablets, Third Edition 465 483 .

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