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Research Article

Stabilization and Target Delivery of Nattokinase Using Compression Coating

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Pages 495-503 | Published online: 26 Sep 2008

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Wen-song Hu, Meng-jie Zhou, Liu-xiu Hu, Kai Huang, Shi-guang Zhao, Sen-he Qian, Zhou Wang, Xi-lin Huang, Jun-Bao Huang, Jian Wang, Xue-yan Liang, Wei Luo, Zheng-lian Xue & Yan Liu. (2023) Preparation and property studies of enteric-soluble oral nattokinase microcapsules with halloysite nanotubes. International Journal of Polymeric Materials and Polymeric Biomaterials 0:0, pages 1-13.
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Sebastien Vankoningsloo, Jean-Pascal Piret, Christelle Saout, Florence Noel, Jorge Mejia, Christos C Zouboulis, Joseph Delhalle, Stephane Lucas & Olivier Toussaint. (2010) Cytotoxicity of multi-walled carbon nanotubes in three skin cellular models: Effects of sonication, dispersive agents and corneous layer of reconstructed epidermis. Nanotoxicology 4:1, pages 84-97.
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Articles from other publishers (17)

Haining Zhuang, Xingyu Chen & Tao Feng. (2022) Research on Technology of Medicinal Functional Food. Processes 10:8, pages 1509.
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Danfeng Li, Lizhen Hou, Miao Hu, Yaxin Gao, Zhiliang Tian, Bei Fan, Shuying Li & Fengzhong Wang. (2022) Recent Advances in Nattokinase-Enriched Fermented Soybean Foods: A Review. Foods 11:13, pages 1867.
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Xueqin Zhou, Liangzhong Liu & Xurui Zeng. (2021) Research progress on the utilisation of embedding technology and suitable delivery systems for improving the bioavailability of nattokinase: A review. Food Structure 30, pages 100219.
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Xuan Zhang, Xiaomei Lyu, Yanjun Tong, Jing Wang, Jianfen Ye & Ruijin Yang. (2020) Chitosan/casein based microparticles with a bilayer shell–core structure for oral delivery of nattokinase. Food & Function 11:12, pages 10799-10816.
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Ali Muhammed Moula Ali & Sri Charan Bindu Bavisetty. (2020) Purification, physicochemical properties, and statistical optimization of fibrinolytic enzymes especially from fermented foods: A comprehensive review. International Journal of Biological Macromolecules 163, pages 1498-1517.
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Zhongmei Liu, Han Zhao, Laichuang Han, Wenjing Cui, Li Zhou & Zhemin Zhou. (2019) Improvement of the acid resistance, catalytic efficiency, and thermostability of nattokinase by multisite‐directed mutagenesis. Biotechnology and Bioengineering 116:8, pages 1833-1843.
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Hye Jin Yoo, Minkyung Kim, Minjoo Kim, Ayoung Lee, Chunmei Jin, Sung Pyo Lee, Tae Su Kim, Sang-Hyun Lee & Jong Ho Lee. (2019) The effects of nattokinase supplementation on collagen–epinephrine closure time, prothrombin time and activated partial thromboplastin time in nondiabetic and hypercholesterolemic subjects. Food & Function 10:5, pages 2888-2893.
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Xiaona Wang, Sifan Jiang, Xinyue Wang, Jie Liao & Zongning Yin. (2015) Preparation and evaluation of nattokinase-loaded self-double-emulsifying drug delivery system. Asian Journal of Pharmaceutical Sciences 10:5, pages 386-395.
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Fatemeh Dabbagh, Manica Negahdaripour, Aydin Berenjian, Abdolazim Behfar, Fatemeh Mohammadi, Mozhdeh Zamani, Cambyz Irajie & Younes Ghasemi. (2014) Nattokinase: production and application. Applied Microbiology and Biotechnology 98:22, pages 9199-9206.
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Jieun Kim, Kyoung-Hwa Choi, Jeong Hwan Kim, Young-Sun Song & Jaeho Cha. (2013) Enhancement of the Thermostability of a Fibrinolytic Enzyme from Bacillus amyloliquefaciens CH51. Journal of Life Science 23:1, pages 15-23.
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Xuetuan Wei, Mingfang Luo, Yuchun Xie, Liangrong Yang, Haojian Li, Lin Xu & Huizhou Liu. (2012) Strain Screening, Fermentation, Separation, and Encapsulation for Production of Nattokinase Functional Food. Applied Biochemistry and Biotechnology 168:7, pages 1753-1764.
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Shan-Yang Lin & Yoshiaki Kawashima. (2012) Current status and approaches to developing press-coated chronodelivery drug systems. Journal of Controlled Release 157:3, pages 331-353.
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Kiran B. Aher, Girija B. Bhavar, Hemant P. Joshi & Sanjay R. Chaudhari. (2011) WITHDRAWN: Recent advances in compression-coated tablets as a controlled drug delivery system. Saudi Pharmaceutical Journal.
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Yoshiko Uesugi, Hiroyuki Kawata, Jun-ichiro Jo, Yoshihiko Saito & Yasuhiko Tabata. (2010) An ultrasound-responsive nano delivery system of tissue-type plasminogen activator for thrombolytic therapy. Journal of Controlled Release 147:2, pages 269-277.
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Wendy Dulin. 2010. Oral Controlled Release Formulation Design and Drug Delivery. Oral Controlled Release Formulation Design and Drug Delivery 205 223 .
Chang-Wei Hsieh, Wen-Chien Lu, Wen-Ching Hsieh, Yun-Peng Huang, Cheng-Hung Lai & Wen-Ching Ko. (2009) Improvement of the stability of nattokinase using γ-polyglutamic acid as a coating material for microencapsulation. LWT - Food Science and Technology 42:1, pages 144-149.
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Durriya Hashmat, M. Harris Shoaib, Zafar Alam Mehmood, Rabia Bushra, Rabia Ismail Yousuf & Fahim Lakhani. (2008) Development of Enteric Coated Flurbiprofen Tablets using Opadry/acryl-eze System—A Technical Note. AAPS PharmSciTech 9:1.
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