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Drug Development and Industrial Pharmacy Volume 33, 2007 - Issue 7
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Research Article

Assessing the Antifungal Activity of a New Oral Lipid-Based Amphotericin B Formulation Following Administration to Rats Infected with Aspergillus Fumigatus

Verica Risovic Division of Pharmaceutics and Biopharmaceutics, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, British Columbia, Canada
,
Mike Rosland Division of Pharmaceutics and Biopharmaceutics, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, British Columbia, Canada
,
Olena Sivak Division of Pharmaceutics and Biopharmaceutics, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, British Columbia, Canada
,
Kishor M. Wasan Division of Pharmaceutics and Biopharmaceutics, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, British Columbia, Canada
&
Karen Bartlett Department of Occupational and Environmental Hygiene, University of British Columbia
Pages 703-707 | Published online: 26 Sep 2008

Citations (15)

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Ronak Savla, Jeff Browne, Vincent Plassat, Kishor M. Wasan & Ellen K. Wasan. (2017) Review and analysis of FDA approved drugs using lipid-based formulations. Drug Development and Industrial Pharmacy 43:11, pages 1743-1758.
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Min Liu, Meiwan Chen & Zhiwen Yang. (2017) Design of amphotericin B oral formulation for antifungal therapy. Drug Delivery 24:1, pages 1-9.
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Articles from other publishers (13)

Mudassar Shahid, Afzal Hussain, Azmat Ali Khan, Amer M. Alanazi, Ahmed L. Alaofi, Mahboob Alam & Mohhammad Ramzan. (2022) Antifungal Cationic Nanoemulsion Ferrying Miconazole Nitrate with Synergism to Control Fungal Infections: In Vitro , Ex Vivo , and In Vivo Evaluations . ACS Omega 7:15, pages 13343-13353.
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Kishor M. Wasan. (2020) Development of an Oral Amphotericin B Formulation as an Alternative Approach to Parenteral Amphotericin B Administration in the Treatment of Blood-Borne Fungal Infections. Current Pharmaceutical Design 26:14, pages 1521-1523.
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Dolores R. Serrano & Aikaterini Lalatsa. (2017) Oral amphotericin B: The journey from bench to market. Journal of Drug Delivery Science and Technology 42, pages 75-83.
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Raquel Fernández-García, Esther de Pablo, María Paloma Ballesteros & Dolores R. Serrano. (2017) Unmet clinical needs in the treatment of systemic fungal infections: The role of amphotericin B and drug targeting. International Journal of Pharmaceutics 525:1, pages 139-148.
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Guillaume Desoubeaux & Carolyn Cray. (2017) Rodent Models of Invasive Aspergillosis due to Aspergillus fumigatus: Still a Long Path toward Standardization. Frontiers in Microbiology 8.
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Masami Ukawa, Hidenori Ando, Taro Shimizu & Tatsuhiro Ishida. 2016. Nanomaterials in Pharmacology. Nanomaterials in Pharmacology 219 238 .
Kuldeep Singh, A.K. Tiwary & Vikas Rana. (2013) Spray dried chitosan–EDTA superior microparticles as solid substrate for the oral delivery of amphotericin B. International Journal of Biological Macromolecules 58, pages 310-319.
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Juan J TorradoDolores R Serrano & Ijeoma F Uchegbu. (2013) The oral delivery of amphotericin B. Therapeutic Delivery 4:1, pages 9-12.
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Sanyog Jain, Pankaj U. Valvi, Nitin K. Swarnakar & Kaushik Thanki. (2012) Gelatin Coated Hybrid Lipid Nanoparticles for Oral Delivery of Amphotericin B. Molecular Pharmaceutics 9:9, pages 2542-2553.
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Jagdishbhai L. Italia, Andrew Sharp, Katharine C. Carter, Peter Warn & M. N. V. Ravi Kumar. (2011) Peroral Amphotericin B Polymer Nanoparticles Lead to Comparable or Superior In Vivo Antifungal Activity to That of Intravenous Ambisome® or Fungizone™. PLoS ONE 6:10, pages e25744.
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P. Gershkovich, E. K. Wasan, M. Lin, O. Sivak, C. G. Leon, J. G. Clement & K. M. Wasan. (2009) Pharmacokinetics and biodistribution of amphotericin B in rats following oral administration in a novel lipid-based formulation. Journal of Antimicrobial Chemotherapy 64:1, pages 101-108.
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Kishor M. Wasan, Sheila J. Thornton, Ian Bell, Rebecca E. Goulding, Michael Gretes, Andrew P. Gray, Robert E.W. Hancock & Barbara Campbell. (2009) The Global Access Initiative at the University of British Columbia (UBC): Availability of UBC Discoveries and Technologies to the Developing World. Journal of Pharmaceutical Sciences 98:3, pages 791-794.
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Kristina Sachs-Barrable, Stephen D. Lee, Ellen K. Wasan, Sheila J. Thornton & Kishor M. Wasan. (2008) Enhancing drug absorption using lipids: A case study presenting the development and pharmacological evaluation of a novel lipid-based oral amphotericin B formulation for the treatment of systemic fungal infections. Advanced Drug Delivery Reviews 60:6, pages 692-701.
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