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Drug Development and Industrial Pharmacy Volume 33, 2007 - Issue 9
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Research Article

Preparation and In Vitro Evaluation of pH, Time-Based and Enzyme-Degradable Pellets for Colonic Drug Delivery

Cui Fude School of Pharmacy, Shenyang Pharmaceutical University, Shenyang City, Liaoning, P.R. China
,
Yang Lei School of Pharmacy, Shenyang Pharmaceutical University, Shenyang City, Liaoning, P.R. China
,
Jin Jie School of Pharmacy, Shenyang Pharmaceutical University, Shenyang City, Liaoning, P.R. China
,
Piao Hongze School of Pharmacy, Shenyang Pharmaceutical University, Shenyang City, Liaoning, P.R. China
,
Lin Wenhui School of Pharmacy, Shenyang Pharmaceutical University, Shenyang City, Liaoning, P.R. China
&
Cun Dongmei School of Pharmacy, Shenyang Pharmaceutical University, Shenyang City, Liaoning, P.R. China
Pages 999-1007 | Published online: 26 Sep 2008

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Chenzhe Gao, Shen Yu, Xiaonan Zhang, Yanxin Dang, Dan-dan Han, Xin Liu, Janchun Han & Mizhou Hui. (2021) Dual Functional Eudragit® S100/L30D-55 and PLGA Colon-Targeted Nanoparticles of Iridoid Glycoside for Improved Treatment of Induced Ulcerative Colitis. International Journal of Nanomedicine 16, pages 1405-1422.
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Wenchang Zhao, Lijun Song, Hongzhu Deng & Hui Yao. (2009) Hydration, Erosion, and Release Behavior of Guar-Based Hydrophilic Matrix Tablets Containing Total Alkaloids of Sophora alopecuroides. Drug Development and Industrial Pharmacy 35:5, pages 594-602.
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Articles from other publishers (16)

Hajar Azehaf, Youcef Benzine, Madjid Tagzirt, Mohamed Skiba & Youness Karrout. (2023) Microbiota-sensitive drug delivery systems based on natural polysaccharides for colon targeting. Drug Discovery Today 28:7, pages 103606.
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Hossein Shahdadi Sardou, Fatemeh Sadeghi, Hadi Afrasiabi Garekani, Abbas Akhgari, Amir Hossein Jafarian, Mohammadreza Abbaspour & Ali Nokhodchi. (2023) Comparison of 5-ASA layered or matrix pellets coated with a combination of ethylcellulose and eudragits L and s in the treatment of ulcerative colitis in rats. International Journal of Pharmaceutics 640, pages 122981.
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Hossein Shahdadi Sardou, Abbas Akhgari, Amir Hooshang Mohammadpour, Ali Beheshti Namdar, Hossein Kamali, Amir Hossein Jafarian, Hadi Afrasiabi Garekani & Fatemeh Sadeghi. (2022) Optimization study of combined enteric and time-dependent polymethacrylates as a coating for colon targeted delivery of 5-ASA pellets in rats with ulcerative colitis. European Journal of Pharmaceutical Sciences 168, pages 106072.
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Swapnil Khadke, Fiona MacDougall & Tariq Islam. 2022. Oral Delivery of Therapeutic Peptides and Proteins. Oral Delivery of Therapeutic Peptides and Proteins 167 198 .
Lijun Song, Liping Liang, Xiaoying Shi, Honglang Chen, Shumin Zhao, Wenfeng Chen, Ruoxia Zhou & Wenchang Zhao. (2019) Optimizing pH-sensitive and time-dependent polymer formula of colonic pH-responsive pellets to achieve precise drug release. Asian Journal of Pharmaceutical Sciences 14:4, pages 413-422.
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Hossein Shahdadi Sardo, Farinaz Saremnejad, Sara Bagheri, Abbas Akhgari, Hadi Afrasiabi Garekani & Fatemeh Sadeghi. (2019) A review on 5-aminosalicylic acid colon-targeted oral drug delivery systems. International Journal of Pharmaceutics 558, pages 367-379.
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Yachao Ren, Lei Jiang, Shuman Yang, Sainan Gao, Hui Yu, Jie Hu, Dandan Hu, Wenbin Mao, Haisheng Peng & Yulong Zhou. (2017) Design and preparation of a novel colon-targeted tablet of hydrocortisone. Brazilian Journal of Pharmaceutical Sciences 53:1.
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Chityal Ganesh Kumar, Yedla Poornachandra & Sujitha Pombala. 2017. Nanostructures for Drug Delivery. Nanostructures for Drug Delivery 1 61 .
Yachao Ren, Lei Jiang, Shuman Yang, Sainan Gao, Hui Yu, Jie Hu, Dandan Hu, Wenbin Mao, Haisheng Peng & Yulong Zhou. (2016) Design and preparation of a novel colon-targeted tablet of hydrocortisone. Brazilian Journal of Pharmaceutical Sciences 52:2, pages 239-250.
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Luca Palugan, Matteo Cerea, Lucia Zema, Andrea Gazzaniga & Alessandra Maroni. (2015) Coated pellets for oral colon delivery. Journal of Drug Delivery Science and Technology 25, pages 1-15.
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Alessandra Maroni, Maria Dorly Del Curto, Lucia Zema, Anastasia Foppoli & Andrea Gazzaniga. (2013) Film coatings for oral colon delivery. International Journal of Pharmaceutics 457:2, pages 372-394.
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Xupin Zhuang, Lei Shi, Bo Zhang, Bowen Cheng & Weimin Kang. (2012) Coaxial solution blown core-shell structure nanofibers for drug delivery. Macromolecular Research 21:4, pages 346-348.
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B. M. Ursekar, P. S. Soni, Abhijit A. Date & M. S. Nagarsenker. (2012) Characterization of Soy Polysaccharide and Its In Vitro and In Vivo Evaluation for Application in Colon Drug Delivery. AAPS PharmSciTech 13:3, pages 934-943.
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Anna Giulia Balducci, Gaia Colombo, Giuseppe Corace, Cristina Cavallari, Lorenzo Rodriguez, Francesca Buttini, Paolo Colombo & Alessandra Rossi. (2011) Layered lipid microcapsules for mesalazine delayed-release in children. International Journal of Pharmaceutics 421:2, pages 293-300.
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Nadir Veiga Vier & Ruth Meri Lucinda-Silva. (2011) Influence of coating on the triamcinolone release of alginate chitosan beads for colonic drug delivery. Natural Science 03:11, pages 955-962.
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Xin Shi, JianPing Li, Yan Tang & Qihua Yang. (2010) pH-Sensitive mesoporous zirconium diphosphonates for controllable colon-targeted delivery. Journal of Materials Chemistry 20:31, pages 6495.
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