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Research Article

Ocular Drug Metabolism of the Bioactivating Antioxidant N-acetylcarnosine for Vision in Ophthalmic Prodrug and Codrug Design and Delivery

Pages 1071-1089 | Published online: 05 Nov 2008

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Read on this site (3)

Wang Lihong, Che Xin, Guo Yongxue, Bian Yiying & Cheng Gang. (2014) Thermoresponsive ophthalmic poloxamer/tween/carbopol in situ gels of a poorly water-soluble drug fluconazole: preparation and in vitro–in vivo evaluation. Drug Development and Industrial Pharmacy 40:10, pages 1402-1410.
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Alan R Hipkiss. (2009) Carnosine, diabetes and Alzheimer’s disease. Expert Review of Neurotherapeutics 9:5, pages 583-585.
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Articles from other publishers (11)

Yaru Wang & Changhong Wang. (2022) Novel Eye Drop Delivery Systems: Advance on Formulation Design Strategies Targeting Anterior and Posterior Segments of the Eye. Pharmaceutics 14:6, pages 1150.
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Megha Barot, Mitesh Patel, Deep Kwatra & Ashim K. Mitra. 2013. Ocular Transporters and Receptors. Ocular Transporters and Receptors 229 248 .
Mark A. Babizhayev, Inna P. Khoroshilova-Maslova & Anne Kasus-Jacobi. (2012) Novel intraocular and systemic absorption drug delivery and efficacy of N-acetylcarnosine lubricant eye drops or carcinine biologics in pharmaceutical usage and therapeutic vision care. Fundamental & Clinical Pharmacology 26:5, pages 644-678.
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Mark A. Babizhayev. (2011) Bioactivation antioxidant and transglycating properties of N‐acetylcarnosine autoinduction prodrug of a dipeptide L‐carnosine in mucoadhesive drug delivery eye‐drop formulation: powerful eye health application technique and therapeutic platform. Drug Testing and Analysis 4:6, pages 468-485.
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Alan R. Hipkiss. (2011) Energy metabolism, proteotoxic stress and age-related dysfunction – Protection by carnosine. Molecular Aspects of Medicine 32:4-6, pages 267-278.
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Mark A Babizhayev. (2010) Designation of imidazole-containing dipeptides as pharmacological chaperones. Human & Experimental Toxicology 30:7, pages 736-761.
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Zhou TianyangZhu LingWang LiyaZhang Junjie. (2011) Ocular Pharmacokinetics of Carnosine 5% Eye Drops Following Topical Application in Rabbit. Journal of Ocular Pharmacology and Therapeutics 27:1, pages 93-97.
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Deep Kwatra, Ravi Vaishya, Ripal Gaudana, Jwala Jwala & Ashim K. Mitra. 2010. Prodrugs and Targeted Delivery. Prodrugs and Targeted Delivery 181 205 .
Mark A Babizhayev. (2010) New Concept in Nutrition for the Maintenance of the Aging Eye Redox Regulation and Therapeutic Treatment of Cataract Disease; Synergism of Natural Antioxidant Imidazole-Containing Amino Acid-Based Compounds, Chaperone, and Glutathione Boosting Agents: A Systemic Perspective on Aging and Longevity Emerged From Studies in Humans. American Journal of Therapeutics 17:4, pages 373-389.
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M.A. Babizhayev. (2009) Potentiation of Intraocular Absorption and Drug Metabolism of N-Acetylcarnosine Lubricant Eye Drops: Drug Interaction with Sight Threatening Lipid Peroxides in the Treatment for Age-Related Eye Diseases. Drug Metabolism and Drug Interactions 24:2-4.
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Alan R. Hipkiss. 2009. 87 154 .

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