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Drug Development and Industrial Pharmacy Volume 35, 2009 - Issue 1
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Research Article

Rational Design of a Stable, Freeze-Dried Virus-Like Particle-Based Vaccine Formulation

R. Lang Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-University, Munich, GermanyCorrespondence[email protected]
,
G. Winter Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-University, Munich, Germany
,
L. Vogt Product Development, CYTOS Biotechnology AG, Schlieren, Switzerland
,
A. Zürcher Product Development, CYTOS Biotechnology AG, Schlieren, Switzerland
,
B. Dorigo Product Development, CYTOS Biotechnology AG, Schlieren, Switzerland
&
B. Schimmele Product Development, CYTOS Biotechnology AG, Schlieren, Switzerland
Pages 83-97 | Published online: 01 Jan 2009

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Hunter McFall-Boegeman & Xuefei Huang. (2022) Mechanisms of cellular and humoral immunity through the lens of VLP-based vaccines. Expert Review of Vaccines 21:4, pages 453-469.
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Braeden Donaldson, Zabeen Lateef, Greg F. Walker, Sarah L. Young & Vernon K. Ward. (2018) Virus-like particle vaccines: immunology and formulation for clinical translation. Expert Review of Vaccines 17:9, pages 833-849.
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Gladys Rosario Ramos Yacasi, Ana Cristina Calpena Campmany, María Antonia Egea Gras, Marta Espina García & María Luisa García López. (2017) Freeze drying optimization of polymeric nanoparticles for ocular flurbiprofen delivery: effect of protectant agents and critical process parameters on long-term stability. Drug Development and Industrial Pharmacy 43:4, pages 637-651.
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Zhi-Liang Zhang, Yuan Le, Jie-Xin Wang & Jian-Feng Chen. (2011) Preparation of stable micron-sized crystalline irbesartan particles for the enhancement of dissolution rate. Drug Development and Industrial Pharmacy 37:11, pages 1357-1364.
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Vartika Srivastava, Kripa N. Nand, Aijaz Ahmad & Ravinder Kumar. (2023) Yeast-Based Virus-like Particles as an Emerging Platform for Vaccine Development and Delivery. Vaccines 11:2, pages 479.
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Kara-Lee Aves, Christoph M. Janitzek, Cyrielle E. Fougeroux, Thor G. Theander & Adam F. Sander. (2022) Freeze-Drying of a Capsid Virus-like Particle-Based Platform Allows Stable Storage of Vaccines at Ambient Temperature. Pharmaceutics 14:6, pages 1301.
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