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Research Article

Preparation and Body Distribution of Freeze-Dried Powder of Ursolic Acid Phospholipid Nanoparticles

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Pages 305-310 | Published online: 01 Mar 2009

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Ran Yin, Tong Li, Jing Xin Tian, Pan Xi & Rui Hai Liu. (2018) Ursolic acid, a potential anticancer compound for breast cancer therapy. Critical Reviews in Food Science and Nutrition 58:4, pages 568-574.
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Anteneh Belete & Karsten Maeder. (2013) Novel aqueous nano-scaled formulations of oleic acid stabilized hydrophobic superparamagnetic iron oxide nanocrystals. Drug Development and Industrial Pharmacy 39:2, pages 186-196.
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SHAMS TABREZ, MEDHA PRIYADARSHINI, MARYAM UROOJ, SHAZI SHAKIL, GHULAM Md ASHRAF, MOHD SHAHNAWAZ KHAN, MOHAMMAD AMJAD KAMAL, QAMRE ALAM, NASIMUDEENR. JABIR, ADEL MOHAMMAD ABUZENADAH, ADEELG. A. CHAUDHARY & GHAZI ABDULLAH DAMANHOURI. (2013) Cancer Chemoprevention by Polyphenols and Their Potential Application as Nanomedicine. Journal of Environmental Science and Health, Part C 31:1, pages 67-98.
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Cheng-Dong Hou, Jie-Xin Wang, Yuan Le, Hai-Kui Zou & Hong Zhao. (2012) Preparation of azithromycin nanosuspensions by reactive precipitation method. Drug Development and Industrial Pharmacy 38:7, pages 848-854.
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Articles from other publishers (26)

Plaban Bhattacharya, Achintya Saha & Souvik Basak. (2023) Analytical method development for exploring pharmacokinetic profile of ursolic acid in rat tissues by high-performance thin-layer chromatography. JPC – Journal of Planar Chromatography – Modern TLC 36:1, pages 9-19.
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Shi-Yao Zhang, Xiao-Lei Sun, Xing-Liang Yang, Peng-Liang Shi, Ling-Chuan Xu & Qing-Mei Guo. (2022) Botany, traditional uses, phytochemistry and pharmacological activity of Crataegus pinnatifida (Chinese hawthorn): a review . Journal of Pharmacy and Pharmacology 74:11, pages 1507-1545.
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Sureshbabu Ram Kumar Pandian, Selvaraj Kunjiappan, Parasuraman Pavadai, Velmurugan Sundarapandian, Vivek Chandramohan & Krishnan Sundar. (2021) Delivery of Ursolic Acid by Polyhydroxybutyrate Nanoparticles for Cancer Therapy: in silico and in vitro Studies. Drug Research 72:02, pages 72-81.
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Manzar Alam, Sabeeha Ali, Sarfraz Ahmed, Abdelbaset Mohamed Elasbali, Mohd Adnan, Asimul Islam, Md. Imtaiyaz Hassan & Dharmendra Kumar Yadav. (2021) Therapeutic Potential of Ursolic Acid in Cancer and Diabetic Neuropathy Diseases. International Journal of Molecular Sciences 22:22, pages 12162.
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Evelina Gudoityte, Odeta Arandarcikaite, Ingrida Mazeikiene, Vidmantas Bendokas & Julius Liobikas. (2021) Ursolic and Oleanolic Acids: Plant Metabolites with Neuroprotective Potential. International Journal of Molecular Sciences 22:9, pages 4599.
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Jingwei Shao, Yifan Fang, Ruirui Zhao, Fangmin Chen, Mingyue Yang, Jiali Jiang, Zixuan Chen, Xiaotian Yuan & Lee Jia. (2020) Evolution from small molecule to nano-drug delivery systems: An emerging approach for cancer therapy of ursolic acid. Asian Journal of Pharmaceutical Sciences 15:6, pages 685-700.
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Arora, Sharma & Tollefsbol. (2019) Combinatorial Epigenetics Impact of Polyphenols and Phytochemicals in Cancer Prevention and Therapy. International Journal of Molecular Sciences 20:18, pages 4567.
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Wen Jinhua. (2019) Ursolic acid: Pharmacokinetics process in vitro and in vivo , a mini review . Archiv der Pharmazie 352:3, pages 1800222.
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Javed Iqbal, Banzeer Ahsan Abbasi, Riaz Ahmad, Tariq Mahmood, Sobia Kanwal, Barkat Ali, Ali Talha Khalil, Sayed Afzal Shah, Muhammad Maqsood Alam & Hussain Badshah. (2018) Ursolic acid a promising candidate in the therapeutics of breast cancer: Current status and future implications. Biomedicine & Pharmacotherapy 108, pages 752-756.
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Xin Ji, Qiao Tang, Peng Pang, Jianping Wu, Thomas Brett Kirk, Jiake Xu, Dong Ma & Wei Xue. (2018) Redox-responsive chemosensitive polyspermine delivers ursolic acid targeting to human breast tumor cells: The depletion of intracellular GSH contents arouses chemosensitizing effects. Colloids and Surfaces B: Biointerfaces 170, pages 293-302.
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Eman Abu-Gharbieh, Naglaa G. Shehab, Ihab M. Almasri & Yasser Bustanji. (2018) Antihyperuricemic and xanthine oxidase inhibitory activities of Tribulus arabicus and its isolated compound, ursolic acid: In vitro and in vivo investigation and docking simulations. PLOS ONE 13:8, pages e0202572.
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Guk Young Ahn, Dong-Hyun Paik, Ki-Young Jeong, Seung-Woon Baek, Rae-Hyoung Kang, Eun Seong Lee & Sung-Wook Choi. (2018) Electrosprayed Folic Acid-Conjugated Ursolic Acid Nanoparticles for Tumor Therapy. Macromolecular Research 26:7, pages 573-576.
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Niege J. C. Furtado, Laetitia Pirson, Hélène Edelberg, Lisa M. Miranda, Cristina Loira-Pastoriza, Véronique Preat, Yvan Larondelle & Christelle André. (2017) Pentacyclic Triterpene Bioavailability: An Overview of In Vitro and In Vivo Studies. Molecules 22:3, pages 400.
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Karina Valdés, Javier Morales, Lennin Rodríguez & Germán Günther. (2016) Potential use of nanocarriers with pentacyclic triterpenes in cancer treatments. Nanomedicine 11:23, pages 3139-3156.
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Ticiano Gomes do Nascimento, Priscilla Fonseca da Silva, Lais Farias Azevedo, Louisianny Guerra da Rocha, Isabel Cristina Celerino de Moraes Porto, Túlio Flávio Accioly Lima e Moura, Irinaldo Diniz Basílio-Júnior, Luciano Aparecido Meireles Grillo, Camila Braga Dornelas, Eduardo Jorge da Silva Fonseca, Eduardo de Jesus Oliveira, Alex Tong Zhang & David G. Watson. (2016) Polymeric Nanoparticles of Brazilian Red Propolis Extract: Preparation, Characterization, Antioxidant and Leishmanicidal Activity. Nanoscale Research Letters 11:1.
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Talita Guieiro Ribeiro Rocha, Sávia Caldeira de Araújo Lopes, Geovani Dantas Cassali, Ênio Ferreira, Emerson Soares Veloso, Elaine Amaral Leite, Fernão Castro Braga, Lucas Antônio Miranda Ferreira, Daniel Balvay, Anikitos Garofalakis, Mônica Cristina Oliveira & Bertrand Tavitian. (2016) Evaluation of Antitumor Activity of Long-Circulating and pH-Sensitive Liposomes Containing Ursolic Acid in Animal Models of Breast Tumor and Gliosarcoma. Integrative Cancer Therapies 15:4, pages 512-524.
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Prasant Nahak, Gourab Karmakar, Priyam Chettri, Biplab Roy, Pritam Guha, Shila Elizabeth Besra, Anjana Soren, Alexey G. Bykov, Alexander V. Akentiev, Boris A. Noskov & Amiya Kumar Panda. (2016) Influence of Lipid Core Material on Physicochemical Characteristics of an Ursolic Acid-Loaded Nanostructured Lipid Carrier: An Attempt To Enhance Anticancer Activity. Langmuir 32:38, pages 9816-9825.
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Sahdeo Prasad, Vivek R. Yadav, Bokyung Sung, Subash C. Gupta, Amit K. Tyagi & Bharat B. Aggarwal. (2016) Ursolic acid inhibits the growth of human pancreatic cancer and enhances the antitumor potential of gemcitabine in an orthotopic mouse model through suppression of the inflammatory microenvironment. Oncotarget 7:11, pages 13182-13196.
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Yu Gao, Zhihong Li, Xiaodong Xie, Chaoqun Wang, Jiali You, Fan Mo, Biyu Jin, Jianzhong Chen, Jingwei Shao, Haijun Chen & Lee Jia. (2015) Dendrimeric anticancer prodrugs for targeted delivery of ursolic acid to folate receptor-expressing cancer cells: Synthesis and biological evaluation. European Journal of Pharmaceutical Sciences 70, pages 55-63.
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Ju Song, Yancai Wang, Yuelin Song, Hokman Chan, Chao Bi, Xiao Yang, Ru Yan, Yitao Wang & Ying Zheng. (2013) Development and Characterisation of Ursolic Acid Nanocrystals Without Stabiliser Having Improved Dissolution Rate and In Vitro Anticancer Activity. AAPS PharmSciTech 15:1, pages 11-19.
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Muthu K. Shanmugam, Xiaoyun Dai, Alan Prem Kumar, Benny K.H. Tan, Gautam Sethi & Anupam Bishayee. (2013) Ursolic acid in cancer prevention and treatment: Molecular targets, pharmacokinetics and clinical studies. Biochemical Pharmacology 85:11, pages 1579-1587.
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Monica Rosa Loizzo, Francesco Menichini & Rosa Tundis. 2013. 1 31 .
K.P. Velikov. 2012. Encapsulation Technologies and Delivery Systems for Food Ingredients and Nutraceuticals. Encapsulation Technologies and Delivery Systems for Food Ingredients and Nutraceuticals 319 391 .
Zhi-Rong Tan, Yao Chen, Gan Zhou, Shan Cao, Xiang-Dong Peng, Yi-Cheng Wang, Xiu-Juan Peng, Wei Zhang & Hong-Hao Zhou. (2010) LC–MS–MS Quantitative Determination of Ursolic Acid in Human Plasma and Its Application to Pharmacokinetic Studies. Chromatographia 72:11-12, pages 1107-1113.
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Hareesh B. Nair, Bokyung Sung, Vivek R. Yadav, Ramaswamy Kannappan, Madan M. Chaturvedi & Bharat B. Aggarwal. (2010) Delivery of antiinflammatory nutraceuticals by nanoparticles for the prevention and treatment of cancer. Biochemical Pharmacology 80:12, pages 1833-1843.
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