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Research Article

Ciprofloxacin Liposomes as Vesicular Reservoirs for Ocular Delivery: Formulation, Optimization, and In Vitro Characterization

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Pages 583-593 | Published online: 01 May 2009

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Read on this site (10)

José Javier López-Cano, Miriam Ana González-Cela-Casamayor, Vanessa Andrés-Guerrero, Rocío Herrero-Vanrell & Irene Teresa Molina-Martínez. (2021) Liposomes as vehicles for topical ophthalmic drug delivery and ocular surface protection. Expert Opinion on Drug Delivery 18:7, pages 819-847.
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Salma M. Mohyeldin, Mohammed M. Mehanna & Nazik A. Elgindy. (2016) Superiority of liquid crystalline cubic nanocarriers as hormonal transdermal vehicle: comparative human skin permeation-supported evidence. Expert Opinion on Drug Delivery 13:8, pages 1049-1064.
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Javed Ali, Mohd Fazil, Mohd Qumbar, Nazia Khan & Asgar Ali. (2016) Colloidal drug delivery system: amplify the ocular delivery. Drug Delivery 23:3, pages 700-716.
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Sicong Geng, Xiaolin Liu, Hang Xu, Cuifang Cai, Yu Zhang, Qing Yao, Helin Xu, Jingxin Gou, Tian Yin, Wei Xiao & Xing Tang. (2016) Clarithromycin ion pair in a liposomal membrane to improve its stability and reduce its irritation caused by intravenous administration. Expert Opinion on Drug Delivery 13:3, pages 337-348.
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Mohammed M. Mehanna, Adel M. Motawaa & Magda W. Samaha. (2015) Nanovesicular carrier-mediated transdermal delivery of tadalafil: i- formulation and physicsochemical characterization. Drug Development and Industrial Pharmacy 41:5, pages 714-721.
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Ning Li, Chun-Yang Zhuang, Mi Wang, Cheng-Guang Sui & Wei-San Pan. (2012) Low molecular weight chitosan-coated liposomes for ocular drug delivery: In vitro and in vivo studies. Drug Delivery 19:1, pages 28-35.
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Raju Jukanti, Praveen Gaddam, Manoj Jalagam & Suresh Bandari. (2011) Transcorneal Permeation of Ciprofloxacin Liposomes: Effect of Surface Charge and Nonionic Surfactants. Journal of Dispersion Science and Technology 32:7, pages 935-942.
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Taís Gratieri, Guilherme M Gelfuso, Renata FV Lopez & Eliana B Souto. (2010) Current efforts and the potential of nanomedicine in treating fungal keratitis. Expert Review of Ophthalmology 5:3, pages 365-384.
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Mohammed M. Mehanna, Hoda A. Elmaradny & Magda W. Samaha. (2010) Mucoadhesive liposomes as ocular delivery system: physical, microbiological, and in vivo assessment. Drug Development and Industrial Pharmacy 36:1, pages 108-118.
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Articles from other publishers (15)

Islam A. Khalil, Bahram Saleh, Dina M. Ibrahim, Clotilde Jumelle, Ann Yung, Reza Dana & Nasim Annabi. (2020) Ciprofloxacin-loaded bioadhesive hydrogels for ocular applications. Biomaterials Science 8:18, pages 5196-5209.
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Jana K. Alwattar, Racha Chouaib, Alia Khalil & Mohammed M. Mehanna. (2020) A novel multifaceted approach for wound healing: Optimization and in vivo evaluation of spray dried tadalafil loaded pro-nanoliposomal powder. International Journal of Pharmaceutics 587, pages 119647.
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Xinyu Zhang, Ying Wei, Zhijun Cao, Ying Xu, Cong Lu, Meiqi Zhao, Jingxin Gou, Tian Yin, Yu Zhang, Haibing He, Yanjiao Wang & Xing Tang. (2020) Aprepitant Intravenous Emulsion Based on Ion Pairing/Phospholipid Complex for Improving Physical and Chemical Stability During Thermal Sterilization. AAPS PharmSciTech 21:3.
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Ankit Jain, Pooja Hurkat & Sanjay K. Jain. (2019) Development of liposomes using formulation by design: Basics to recent advances. Chemistry and Physics of Lipids 224, pages 104764.
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Hamdy M. Dawaba & Aya M. Dawaba. (2018) Development and evaluation of extended release ciprofloxacin HCl ocular inserts employing natural and synthetic film forming agents. Journal of Pharmaceutical Investigation 49:2, pages 245-257.
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Orchid Ashraf, Maha Nasr, Marianne Nebsen, Azza Mohamed Ahmed Said & Omaima Sammour. (2018) In vitro stabilization and in vivo improvement of ocular pharmacokinetics of the multi-therapeutic agent baicalin: Delineating the most suitable vesicular systems. International Journal of Pharmaceutics 539:1-2, pages 83-94.
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Marion Dubald, Sandrine Bourgeois, Véronique Andrieu & Hatem Fessi. (2018) Ophthalmic Drug Delivery Systems for Antibiotherapy—A Review. Pharmaceutics 10:1, pages 10.
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Mohammed Maher Mehanna, Nouran Abd El-Kader & Magda Wadih Samaha. (2017) Liposomes as potential carriers for ketorolac ophthalmic delivery: formulation and stability issues. Brazilian Journal of Pharmaceutical Sciences 53:2.
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Bhupinder Singh, Sumant Saini, Shikha Lohan & Sarwar Beg. 2017. Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes. Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes 110 148 .
Ankit Jain & Sanjay K. Jain. (2016) In vitro release kinetics model fitting of liposomes: An insight. Chemistry and Physics of Lipids 201, pages 28-40.
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Nazik A. Elgindy, Mohammed M. Mehanna & Salma M. Mohyeldin. (2016) Self-assembled nano-architecture liquid crystalline particles as a promising carrier for progesterone transdermal delivery. International Journal of Pharmaceutics 501:1-2, pages 167-179.
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Mohammed M. Mehanna, Jana K. Alwattar & Hoda A. Elmaradny. (2015) Optimization, physicochemical characterization and in vivo assessment of spray dried emulsion: A step toward bioavailability augmentation and gastric toxicity minimization. International Journal of Pharmaceutics 496:2, pages 766-779.
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Mohammed M. Mehanna, Salma M. Mohyeldin & Nazik A. Elgindy. (2014) Respirable nanocarriers as a promising strategy for antitubercular drug delivery. Journal of Controlled Release 187, pages 183-197.
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Keda Zhang, Ming Chen, Gerhard K.E. Scriba, Michael H. Abraham, Alfred Fahr & Xiangli Liu. (2011) Linear Free Energy Relationship Analysis of Retention Factors in Cerasome Electrokinetic Chromatography Intended for Predicting Drug Skin Permeation. Journal of Pharmaceutical Sciences 100:8, pages 3105-3113.
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Mohammed M. Mehanna, Adel M. Motawaa & Magda W. Samaha. (2011) Tadalafil Inclusion in Microporous Silica as Effective Dissolution Enhancer: Optimization of Loading Procedure and Molecular State Characterization. Journal of Pharmaceutical Sciences 100:5, pages 1805-1818.
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