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Research Articles

In vitro and in vivo evaluation of puerarin-loaded PEGylated mesoporous silica nanoparticles

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Pages 2031-2037 | Received 18 Oct 2015, Accepted 11 May 2016, Published online: 09 Jun 2016

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Mahvash Hesari, Pantea Mohammadi, Fatemeh Khademi, Dareuosh Shackebaei, Saeideh Momtaz, Narges Moasefi, Mohammad Hosein Farzaei & Mohammad Abdollahi. (2021) Current Advances in the Use of Nanophytomedicine Therapies for Human Cardiovascular Diseases. International Journal of Nanomedicine 16, pages 3293-3315.
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Jun-Yong Wu, Yong-Jiang Li, Meng Han, Xiong-Bin Hu, Le Yang, Jie-Min Wang & Da-Xiong Xiang. (2018) A microemulsion of puerarin–phospholipid complex for improving bioavailability: preparation, in vitro and in vivo evaluations. Drug Development and Industrial Pharmacy 44:8, pages 1336-1341.
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Articles from other publishers (14)

Haritha Kirla, David J. Henry, Shirley Jansen, Peter L. Thompson & Juliana Hamzah. (2023) Use of Silica Nanoparticles for Drug Delivery in Cardiovascular Disease. Clinical Therapeutics 45:11, pages 1060-1068.
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Jayesh Gupta, Mural Quadros & Munira Momin. (2023) Mesoporous silica nanoparticles: Synthesis and multifaceted functionalization for controlled drug delivery. Journal of Drug Delivery Science and Technology 81, pages 104305.
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Rema Sreenivasan Soumya & Kozhiparambil Gopalan Raghu. (2023) Recent advances on nanoparticle-based therapies for cardiovascular diseases. Journal of Cardiology 81:1, pages 10-18.
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Shiqi Guo, Yanan Shi, Yanzi Liang, Lanze Liu, Kaoxiang Sun & Youxin Li. (2021) Relationship and improvement strategies between drug nanocarrier characteristics and hemocompatibility: What can we learn from the literature. Asian Journal of Pharmaceutical Sciences 16:5, pages 551-576.
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Hongfei Chen, Long He, Da Li, Feng Jin & Yanqiu Ai. (2021) Propofol-loaded nanomicelle with improved anesthetic, pharmacokinetic, hemocompatibility, safety, and permeation profiles. Arabian Journal of Chemistry 14:5, pages 103093.
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Jonas G. Croissant, Kimberly S. Butler, Jeffrey I. Zink & C. Jeffrey Brinker. (2020) Synthetic amorphous silica nanoparticles: toxicity, biomedical and environmental implications. Nature Reviews Materials 5:12, pages 886-909.
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Assaf Bar & Smadar Cohen. (2020) Inducing Endogenous Cardiac Regeneration: Can Biomaterials Connect the Dots?. Frontiers in Bioengineering and Biotechnology 8.
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Tongkai Chen, Wei Liu, Sha Xiong, Dongli Li, Shuhuan Fang, Zhenfeng Wu, Qi Wang & Xiaojia Chen. (2019) Nanoparticles Mediating the Sustained Puerarin Release Facilitate Improved Brain Delivery to Treat Parkinson’s Disease. ACS Applied Materials & Interfaces 11:48, pages 45276-45289.
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Jing Guo, Xiaowei Xing, Na Lv, Jingjie Zhao, Yusheng Liu, Huiping Gong, Yimeng Du, Qinghua Lu & Zhaoqiang Dong. (2019) Therapy for myocardial infarction: In vitro and in vivo evaluation of puerarin-prodrug and tanshinone co-loaded lipid nanoparticulate system. Biomedicine & Pharmacotherapy 120, pages 109480.
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Fatemeh Farjadian, Amir Roointan, Soliman Mohammadi-Samani & Majid Hosseini. (2019) Mesoporous silica nanoparticles: Synthesis, pharmaceutical applications, biodistribution, and biosafety assessment. Chemical Engineering Journal 359, pages 684-705.
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K. Tamarov, S. Näkki, W. Xu & V.-P. Lehto. (2018) Approaches to improve the biocompatibility and systemic circulation of inorganic porous nanoparticles. Journal of Materials Chemistry B 6:22, pages 3632-3649.
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Andrea M. Mebert, Carolyn J. Baglole, Martin F. Desimone & Dusica Maysinger. (2017) Nanoengineered silica: Properties, applications and toxicity. Food and Chemical Toxicology 109, pages 753-770.
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Kehua Jiang, Hongbo Chen, Kun Tang, Wei Guan, Hui Zhou, Xiaolin Guo, Zhiqiang Chen, Zhangqun Ye & Hua Xu. (2017) Puerarin inhibits bladder cancer cell proliferation through the mTOR/p70S6K signaling pathway. Oncology Letters.
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Zhaoqiang Dong, Jing Guo, Xiaowei Xing, Xuguang Zhang, Yimeng Du & Qinghua Lu. (2017) RGD modified and PEGylated lipid nanoparticles loaded with puerarin: Formulation, characterization and protective effects on acute myocardial ischemia model. Biomedicine & Pharmacotherapy 89, pages 297-304.
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