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Drug Development and Industrial Pharmacy Volume 43, 2017 - Issue 2
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Research Articles

Quality by design (QbD), Process Analytical Technology (PAT), and design of experiment applied to the development of multifunctional sunscreens

Daniela D’Almeida PeresDepartment of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brasil;
,
Maira Bueno AriedeDepartment of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brasil;
,
Thalita Marcilio CandidoDepartment of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brasil;
,
Tania Santos de AlmeidaCBIOS, Universidade Lusófona, Campo Grande 376, Lisbon, Portugal
,
Felipe Rebello LourençoDepartment of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brasil;
,
Vladi Olga ConsiglieriDepartment of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brasil;
,
Telma Mary KanekoDepartment of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brasil;
,
Maria Valéria Robles VelascoDepartment of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brasil;
&
André Rolim BabyDepartment of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brasil; Correspondence[email protected]
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Pages 246-256 | Received 18 Mar 2016, Accepted 12 Sep 2016, Published online: 13 Oct 2016

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Yoon Tae Goo, Sangkil Lee, Ji Yeh Choi, Min Song Kim, Gi Hyeong Sin, Sun Ho Hong, Chang Hyun Kim, Seh Hyon Song & Young Wook Choi. (2022) Enhanced oral absorption of insulin: hydrophobic ion pairing and a self-microemulsifying drug delivery system using a D-optimal mixture design. Drug Delivery 29:1, pages 2831-2845.
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Camila Areias Oliveira, Camila Forster, Patrícia Léo & Carlota Rangel-Yagui. (2022) Development of triblock polymersomes for catalase delivery based on quality by design environment. Journal of Dispersion Science and Technology 43:1, pages 126-135.
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Celia Maria Vargas da Costa Buzzo, Attilio Converti, José Alexsandro da Silva & Alexsandra Conceição Apolinário. (2021) Quality by design enabled the development of stable and effective oil-in-water emulsions at compounding pharmacy: the case of a sunscreen formulation. Pharmaceutical Development and Technology 26:10, pages 1090-1101.
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Articles from other publishers (23)

Olubisi E. Adeyi, Oluwatobi T. Somade, Samson A. Rahman, Boluwatife T. Sobowale, Abimbola E. Ojeyemi, Isaiah M. Abati, Olajumoke O. Olufuwa, Gloria M. Olusegun & Olamide R. Soetan. (2023) The effect of ferulic acid on 2-methoxyethanol-induced spermatotoxicity, hematotoxicity and hepatotoxicity in rats. Journal of Umm Al-Qura University for Applied Sciences.
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Maíra de Oliveira Bispo, Ana Lucía Morocho-Jácome, Cassiano Carlos Escudeiro, Renata Miliani Martinez, Claudinéia Aparecida Sales de Oliveira Pinto, Catarina Rosado, Maria Valéria Robles Velasco & André Rolim Baby. (2023) Photoprotective Efficacy of the Association of Rosmarinic Acid 0.1% with Ethylhexyl Methoxycinnamate and Avobenzone. Cosmetics 10:1, pages 11.
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Bruna Bertoloni dos Santos, Ana Lucía Morocho-Jácome, Zulita Adriana Prieto, Mohammad Hossein Morowvat, Fabiana Vieira Lima, Maria Valéria Robles Velasco, João Carlos Monteiro de Carvalho & André Rolim Baby. 2023. Algae Materials. Algae Materials 285 312 .
Nadia Ruscinc, Ana Lucía Morocho‐Jácome, Renata Miliani Martinez, Wagner Vidal Magalhães, Cassiano Carlos Escudeiro, Jeanine Giarolla, Catarina Rosado, Maria Valéria Robles Velasco & André Rolim Baby. (2022) Vaccinium myrtillus L. extract associated with octocrylene, bisoctrizole, and titanium dioxide: in vitro and in vivo tests to evaluate safety and efficacy . Journal of Cosmetic Dermatology 21:10, pages 4765-4774.
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Thalita Marcílio Cândido, Maíra Bueno Ariede, Claudinéia Aparecida Sales de Oliveira Pinto, Felipe Rebello Lourenço, Catarina Rosado, Maria Valéria Robles Velasco & André Rolim Baby. (2022) Prospecting In Vitro Antioxidant and Photoprotective Properties of Rosmarinic Acid in a Sunscreen System Developed by QbD Containing Octyl p-Methoxycinnamate and Bemotrizinol. Cosmetics 9:2, pages 29.
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Manuschanok Jampa, Khaetthareeya Sutthanut, Natthida Weerapreeyakul, Wipawee Tukummee, Jintanaporn Wattanathorn & Suparporn Muchimapura. (2022) Multiple Bioactivities of Manihot esculenta Leaves: UV Filter, Anti-Oxidation, Anti-Melanogenesis, Collagen Synthesis Enhancement, and Anti-Adipogenesis. Molecules 27:5, pages 1556.
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Sanela M. Savic, Nebojsa D. Cekic, Sasa R. Savic, Tanja M. Ilic & Snezana D. Savic. (2021) ‘All‐natural’ anti‐wrinkle emulsion serum with Acmella oleracea extract: A design of experiments (DoE) formulation approach, rheology and in vivo skin performance/efficacy evaluation . International Journal of Cosmetic Science 43:5, pages 530-546.
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Denise Rampini, Renan Vinícius de Araújo, Rodrigo Esteves Foitinho, Felipe Rebello Lourenço & Jeanine Giarolla. (2021) Analytical Quality by Design as an Important Tool to Determine the Best Analytical Conditions for Isoniazid and Its Respective Succinylated Prodrug. Journal of AOAC INTERNATIONAL 104:1, pages 239-247.
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André Rolim Baby & Ana Lucía Morocho-Jácome. 2021. 63 93 .
Andressa Costa de Oliveira, Ana Lucía Morocho-Jácome, Cibele Ribeiro de Castro Lima, Gabriela Argollo Marques, Maíra de Oliveira Bispo, Amanda Beatriz de Barros, João Guilherme Costa, Tânia Santos de Almeida, Catarina Rosado, João Carlos Monteiro de Carvalho, Maria Valéria Robles Velasco & André Rolim Baby. 2021. Microalgae. Microalgae 313 338 .
Alexandra A. Hübner, Fernanda D. Sarruf, Camila A. Oliveira, Alberto V. Neto, Dominique C. H. Fischer, Edna T. M. Kato, Felipe R. Lourenço, André Rolim Baby & Elfriede M. Bacchi. (2020) Safety and Photoprotective Efficacy of a Sunscreen System Based on Grape Pomace (Vitis vinifera L.) Phenolics from Winemaking. Pharmaceutics 12:12, pages 1148.
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Paula Beatriz Silva Passarin & Felipe Rebello Lourenço. (2020) Modeling an in silico platform to predict chromatographic profiles of UV filters using ChromSimulator. Microchemical Journal 157, pages 105002.
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Fernanda D. Sarruf, Thalita M. Cândido, Camila A. Oliveira, Nádia A. Bou‐Chacra, Maria V. Robles Velasco & André R. Baby. (2019) Influence of Shea ( Butyrospermum parkii ) butter, TiO 2 and ethylhexyl methoxycinnamate on physical parameters and in vitro photoprotective efficacy . Journal of Cosmetic Dermatology 19:8, pages 2076-2085.
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Yoon Tae Goo, Sun Young Park, Bo Ram Chae, Ho Yub Yoon, Chang Hyun Kim, Ji Yeh Choi, Seh Hyon Song & Young Wook Choi. (2020) Optimization of solid self-dispersing micelle for enhancing dissolution and oral bioavailability of valsartan using Box-Behnken design. International Journal of Pharmaceutics 585, pages 119483.
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Cătălina Bogdan, Anca Pop, Sonia M. Iurian, Daniela Benedec & Mirela L. Moldovan. (2020) Research Advances in the Use of Bioactive Compounds from Vitis vinifera By-Products in Oral Care. Antioxidants 9:6, pages 502.
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Maíra Bueno Ariede, Ana Lucia Morocho-Jácome, Thalita Marcílio Candido, Felipe Rebello Lourenço, Edna Tomiko Myiake Kato, Fabiana Vieira Lima, Catarina Rosado, Maria Valéria Robles Velasco, João Carlos Monteiro de Carvalho & André Rolim Baby. (2020) Is the Botryococcus braunii Dry Biomass an Adjuvant for Anti-UVB Topical Formulations?. Scientia Pharmaceutica 88:2, pages 22.
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Sanela SavićM.M., Nebojša CekićD.D. & Saša SavićR.R.. (2020) D-optimal design of experiments and comprehensive rheological analysis in the development of natural anti-aging creams. Advanced Technologies 9:2, pages 29-40.
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Kiriiri Geoffrey, A.N. Mwangi & S.M. Maru. (2019) Sunscreen products: Rationale for use, formulation development and regulatory considerations. Saudi Pharmaceutical Journal 27:7, pages 1009-1018.
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Catarina Rosado, Viviane Kaori Tokunaga, Rafael Sauce, Camila Areias de Oliveira, Fernanda Daud Sarruf, Roberto Parise-Filho, Elisabete Maurício, Tânia Santos de Almeida, Maria Valéria Robles Velasco & André Rolim Baby. (2019) Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant. Frontiers in Physiology 10.
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Isa Martins Fukuda, Camila Francini Fidelis Pinto, Camila dos Santos Moreira, Alessandro Morais Saviano & Felipe Rebello Lourenço. (2018) Design of Experiments (DoE) applied to Pharmaceutical and Analytical Quality by Design (QbD). Brazilian Journal of Pharmaceutical Sciences 54:spe.
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Daniela D'Almeida Peres, Fernanda Daud Sarruf, Camila Areias de Oliveira, Maria Valéria Robles Velasco & André Rolim Baby. (2018) Ferulic acid photoprotective properties in association with UV filters: multifunctional sunscreen with improved SPF and UVA-PF. Journal of Photochemistry and Photobiology B: Biology 185, pages 46-49.
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Débora Cristina de Oliveira, Leandro Augusto Calixto, Isa Martins Fukuda, Alessandro Morais Saviano, Adir José Moreira, Yoshio Kawano, Ronaldo Domingues Mansano, Terezinha de Jesus Andreoli Pinto & Felipe Rebello Lourenço. (2018) Compatibility of Polyvinyl Chloride (PVC) Medical Devices and Other Polymeric Materials with Reactive Ion Etching (RIE) and Inductively Couple Plasma (ICP) Sterilization Using a Quality by Design (QbD) Approach. Journal of Pharmaceutical Innovation 13:2, pages 110-120.
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Selda Dogan Calhan, Ebru Derici Eker & Nefise Ozlen Sahin. (2017) Quality by design (QbD) and process analytical technology (PAT) applications in pharmaceutical industry. European Journal of Chemistry 8:4, pages 430-433.
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