451
Views
57
CrossRef citations to date
0
Altmetric
Research Articles

A combination of complexation and self-nanoemulsifying drug delivery system for enhancing oral bioavailability and anticancer efficacy of curcumin

, , , , , & show all
Pages 847-861 | Received 02 May 2016, Accepted 19 Sep 2016, Published online: 06 Oct 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Mohammad A. Obeid, Manal Alsaadi & Alaa A. Aljabali. (2023) Recent updates in curcumin delivery. Journal of Liposome Research 33:1, pages 53-64.
Read now
Eesha Shukla, Divya Dhatri Kara, Tanvi Katikala & Mahalaxmi Rathnanand. (2023) Self-nanoemulsifying drug delivery systems (SNEDDS) of anti-cancer drugs: a multifaceted nanoplatform for the enhancement of oral bioavailability. Drug Development and Industrial Pharmacy 49:1, pages 1-16.
Read now
Sha Bao, Yanqin Zhang, Jing Ye, Yujin Zhu, Rui Li, Xiaohong Xu & Quan Zhang. (2021) Self-assembled micelles enhance the oral delivery of curcumin for the management of alcohol-induced tissue injury. Pharmaceutical Development and Technology 26:8, pages 880-889.
Read now
Heshu Sulaiman Rahman, Hemn Hassan Othman, Nahidah Ibrahim Hammadi, Swee Keong Yeap, Kawa Mohammad Amin, Nozlena Abdul Samad & Noorjahan Banu Alitheen. (2020) Novel Drug Delivery Systems for Loading of Natural Plant Extracts and Their Biomedical Applications. International Journal of Nanomedicine 15, pages 2439-2483.
Read now
Umesh Kannamangalam Vijayan, Sadineni Varakumar, Sushant Sole & Rekha S. Singhal. (2020) Enhancement of loading and oral bioavailability of curcumin loaded self-microemulsifying lipid carriers using Curcuma oleoresins. Drug Development and Industrial Pharmacy 46:6, pages 889-898.
Read now
Ying Liu, Peiwen Huang, Xuefeng Hou, Fei Yan, Zifei Jiang, Jiangpei Shi, Xingmei Xie, Junyi Shen, Qiangyuan Fan, Zhi Wang & Nianping Feng. (2019) Hybrid curcumin–phospholipid complex-near-infrared dye oral drug delivery system to inhibit lung metastasis of breast cancer. International Journal of Nanomedicine 14, pages 3311-3330.
Read now
Yingpeng Tong, Qin Zhang, Wen Shi & Jianxin Wang. (2019) Mechanisms of oral absorption improvement for insoluble drugs by the combination of phospholipid complex and SNEDDS. Drug Delivery 26:1, pages 1155-1166.
Read now
Ying-Yuan Lu, Wen-Bing Dai, Xin Wang, Xiao-Wei Wang, Jun-Yi Liu, Pu Li, Ya-Qing Lou, Chuang Lu, Qiang Zhang & Guo-Liang Zhang. (2018) Effects of crystalline state and self-nanoemulsifying drug delivery system (SNEDDS) on oral bioavailability of the novel anti-HIV compound 6-benzyl-1-benzyloxymethyl-5-iodouracil in rats. Drug Development and Industrial Pharmacy 44:2, pages 329-337.
Read now

Articles from other publishers (48)

Khushboo Bhardwaj, Arun Sharma, Rajan Kumar, Varnit Tyagi & Rajesh Kumar. (2024) Improving Oral Bioavailability of Herbal Drugs: A Focused Review of Self-Emulsifying Drug Delivery System for Colon Cancer. Current Drug Delivery 21:3, pages 389-402.
Crossref
Kamoru A. Adedokun, Sikiru O. Imodoye, Zwanden S. Yahaya, Ifeoluwa T. Oyeyemi, Ibrahim O. Bello, Mujidat T. Adeyemo‐Imodoye, Malik A. Sanusi & Ramat T. Kamorudeen. 2023. Polyphenols. Polyphenols 188 224 .
RASHMI BAGRI & RAVOURU NAGARAJU. (2023) FIXED DOSE COMBINATION THERAPY OF IBRUTINIB AND QUERCETIN BY SNEDDS-DEVELOPMENT AND EVALUATION BY DESIGN OF EXPERIMENT. International Journal of Applied Pharmaceutics, pages 93-105.
Crossref
Jai Bharti Sharma, Shailendra Bhatt, Abhishek Tiwari, Varsha Tiwari, Manish Kumar, Ravinder Verma, Deepak Kaushik, Tarun Virmani, Girish Kumar, Omkulthom Al kamaly, Asmaa Saleh, Mohammed Khalid Parvez & Abdulsalam Alhalmi. (2023) Statistical optimization of tetrahydrocurcumin loaded solid lipid nanoparticles using Box Behnken design in the management of streptozotocin-induced diabetes mellitus. Saudi Pharmaceutical Journal 31:9, pages 101727.
Crossref
R. Manasa & Mahesh Shivananjappa. 2023. Advances in Novel Formulations for Drug Delivery. Advances in Novel Formulations for Drug Delivery 449 472 .
Xiaojuan Liu, Yanping Lin, Kangfei Yao, Junting Xie, Jie Xiao & Yong Cao. (2023) Increasing β-carotene bioavailability and bioactivity in spinach demonstrated using excipient nanoemulsions—especially those of long-chain triglycerides. Food Chemistry 404, pages 134194.
Crossref
Yingpeng Tong, Wen Shi, Qin Zhang & Jianxin Wang. (2023) Preparation, Characterization, and In Vivo Evaluation of Gentiopicroside-Phospholipid Complex (GTP-PC) and Its Self-Nanoemulsion Drug Delivery System (GTP-PC-SNEDDS). Pharmaceuticals 16:1, pages 99.
Crossref
Vivek Verma, Pratikkumar Patel, Kevin M. Ryan, Sarah Hudson & Luis Padrela. (2023) Production of hydrochlorothiazide nanoparticles with increased permeability using top-spray coating process. The Journal of Supercritical Fluids 192, pages 105788.
Crossref
Leander Corrie, Jaskiran Kaur, Ankit Awasthi, Sukriti Vishwas, Monica Gulati, Sumant Saini, Bimlesh Kumar, Narendra Kumar Pandey, Gaurav Gupta, Harish Dureja, Dinesh Kumar Chellapan, Kamal Dua, Devesh Tewari & Sachin Kumar Singh. (2022) Multivariate Data Analysis and Central Composite Design-Oriented Optimization of Solid Carriers for Formulation of Curcumin-Loaded Solid SNEDDS: Dissolution and Bioavailability Assessment. Pharmaceutics 14:11, pages 2395.
Crossref
Mohammad Ekrami, Ali Ekrami, Rezvan Esmaeily & Zahra Emam-Djomeh. 2022. Biopolymers in Nutraceuticals and Functional Foods. Biopolymers in Nutraceuticals and Functional Foods 545 580 .
Russel Tonjan & Dilpreet Singh. (2022) Functional Excipients and Novel Drug Delivery Scenario in Self-nanoemulsifying Drug Delivery System: A Critical Note. Pharmaceutical Nanotechnology 10:5, pages 368-383.
Crossref
Mrugank Pandya, Bappaditya Chatterjee & Srikar Ganti. (2022) Self-emulsifying Drug Delivery System for Oral Anticancer Therapy: Constraints and Recent Development. Current Pharmaceutical Design 28:31, pages 2538-2553.
Crossref
Muhammad Abdullah, Tasmina Kanwal, Ali Asgher Shuja, Komal Rao, Khadija Rehman, Muhammad Kawish, Shabana Usman Simjee, Sirajuddin & Muhammad Raza Shah. (2022) Synthesis and characterization of cinnamic acid based glyceride and its application for developing self-nanoemulsifying drug delivery system for curcumin oral delivery. Journal of Molecular Structure 1263, pages 133131.
Crossref
Saima Mahmood, Prapanna Bhattarai, Nauman Rahim Khan, Zakia Subhan, Ghulam Razaque, Hassan A. Albarqi, Abdulsalam A. Alqahtani, Ali Alasiri & Lin Zhu. (2022) An Investigation for Skin Tissue Regeneration Enhancement/Augmentation by Curcumin-Loaded Self-Emulsifying Drug Delivery System (SEDDS). Polymers 14:14, pages 2904.
Crossref
Kênia Alves Barcelos, Carolina Rodrigues Mendonça, Matias Noll, Ana Flávia Botelho, Cristiane Raquel Dias Francischini & Marco Augusto Machado Silva. (2022) Antitumor Properties of Curcumin in Breast Cancer Based on Preclinical Studies: A Systematic Review. Cancers 14:9, pages 2165.
Crossref
Rubiya Khursheed, Sachin Kumar Singh, Bimlesh Kumar, Sheetu Wadhwa, Monica Gulati, Anupriya A, Ankit Awasthi, Sukriti Vishwas, Jaskiran Kaur, Leander Corrie, Arya K.R.Rajan Kumar, Niraj Kumar Jha, Piyush Kumar Gupta, Flavia Zacconi, Kamal Dua, Nitin Chitranshi, Gulam Mustafa & Ankit Kumar. (2022) Self-nanoemulsifying composition containing curcumin, quercetin, Ganoderma lucidum extract powder and probiotics for effective treatment of type 2 diabetes mellitus in streptozotocin induced rats. International Journal of Pharmaceutics 612, pages 121306.
Crossref
Shaimaa A. Khalid, Kholoud K. Arafa & Ibrahim M. El-Sherbiny. 2022. Systems of Nanovesicular Drug Delivery. Systems of Nanovesicular Drug Delivery 55 68 .
Viviana di Giacomo, Claudio Ferrante, Luigi Menghini & Giustino Orlando. 2022. Industrial Hemp. Industrial Hemp 173 190 .
Rubiya Khursheed, Sachin Kumar Singh, Sheetu Wadhwa, Monica Gulati, Bhupinder Kapoor, Subheet Kumar Jain, Kuppusamy Gowthamarajan, Flavia Zacconi, Dinesh Kumar Chellappan, Gaurav Gupta, Niraj Kumar Jha, Piyush Kumar Gupta & Kamal Dua. (2021) Development of mushroom polysaccharide and probiotics based solid self-nanoemulsifying drug delivery system loaded with curcumin and quercetin to improve their dissolution rate and permeability: State of the art. International Journal of Biological Macromolecules 189, pages 744-757.
Crossref
Meiao Tan, Jintong Ye, Min Zhao, Xuehong Ke, Keer Huang & Huabao Liu. (2021) Recent developments in the regulation of cholesterol transport by natural molecules. Phytotherapy Research 35:10, pages 5623-5633.
Crossref
Hasriadi, Peththa Wadu Dasuni Wasana, Opa Vajragupta, Pornchai Rojsitthisak & Pasarapa Towiwat. (2021) Mechanistic Insight into the Effects of Curcumin on Neuroinflammation-Driven Chronic Pain. Pharmaceuticals 14:8, pages 777.
Crossref
Natália A. D'Angelo, Mariana A. Noronha, Isabelle S. Kurnik, Mayra C.C. Câmara, Jorge M. Vieira, Luís Abrunhosa, Joana T. Martins, Thais F.R. Alves, Louise L. Tundisi, Janaína A. Ataide, Juliana S.R. Costa, Angela F. Jozala, Laura O. Nascimento, Priscila G. Mazzola, Marco V. Chaud, António A. Vicente & André M. Lopes. (2021) Curcumin encapsulation in nanostructures for cancer therapy: A 10-year overview. International Journal of Pharmaceutics 604, pages 120534.
Crossref
Jai Bharti SharmaShailendra Bhatt, Vipin SainiManish Kumar. (2021) Pharmacokinetics and Pharmacodynamics of Curcumin-Loaded Solid Lipid Nanoparticles in the Management of Streptozotocin-Induced Diabetes Mellitus: Application of Central Composite Design. ASSAY and Drug Development Technologies 19:4, pages 262-279.
Crossref
Delaram Babadi, Simin Dadashzadeh, Mahraz Osouli, Zahra Abbasian, Maryam Sadat Daryabari, Sima Sadrai & Azadeh Haeri. (2021) Biopharmaceutical and pharmacokinetic aspects of nanocarrier-mediated oral delivery of poorly soluble drugs. Journal of Drug Delivery Science and Technology 62, pages 102324.
Crossref
Alicia S. Ombredane, Vitória R. P. Silva, Laise R. Andrade, Willie O. Pinheiro, Mayara Simonelly, Jaqueline V. Oliveira, Andréia C. Pinheiro, Gabriel F. Gonçalves, Gisela J. Felice, Mônica P. Garcia, Patrícia M. Campos, Glécia V. S. Luz & Graziella A. Joanitti. (2021) In Vivo Efficacy and Toxicity of Curcumin Nanoparticles in Breast Cancer Treatment: A Systematic Review. Frontiers in Oncology 11.
Crossref
Tasmina Kanwal, Salim Saifullah, Jawad ur Rehman, Muhammad Kawish, Anam Razzak, Rukesh Maharjan, Muhammad Imran, Imdad Ali, Talat Roome, Shabana Usman Simjee & Muhammad Raza Shah. (2021) Design of absorption enhancer containing self-nanoemulsifying drug delivery system (SNEDDS) for curcumin improved anti-cancer activity and oral bioavailability. Journal of Molecular Liquids 324, pages 114774.
Crossref
Shashank Chaturvedi & Kamla Pathak. 2021. Advanced Drug Delivery Systems in the Management of Cancer. Advanced Drug Delivery Systems in the Management of Cancer 299 318 .
Nabila M. Sweed, Ahmed M. Fayez, Soad Z. El-Emam & Marwa H. S. Dawoud. (2020) Response surface optimization of self nano-emulsifying drug delivery system of rosuvastatin calcium for hepatocellular carcinoma. Journal of Pharmaceutical Investigation 51:1, pages 85-101.
Crossref
Ghanshyam R. Parmar & Girish U. Sailor. 2021. Nanocarriers: Drug Delivery System. Nanocarriers: Drug Delivery System 281 301 .
Parijat Pandey, Nisha Gulati, Manish Makhija, Deepika Purohit & Harish Dureja. (2020) Nanoemulsion: A Novel Drug Delivery Approach for Enhancement of Bioavailability. Recent Patents on Nanotechnology 14:4, pages 276-293.
Crossref
Ankita Tiwari & Sanjay K. Jain. (2020) Curcumin Based Drug Delivery Systems for Cancer Therapy. Current Pharmaceutical Design 26:42, pages 5430-5440.
Crossref
Aristote B. Buya, Ana Beloqui, Patrick B. Memvanga & Véronique Préat. (2020) Self-Nano-Emulsifying Drug-Delivery Systems: From the Development to the Current Applications and Challenges in Oral Drug Delivery. Pharmaceutics 12:12, pages 1194.
Crossref
Zhenqi Liu, John D. Smart & Ananth S. Pannala. (2020) Recent developments in formulation design for improving oral bioavailability of curcumin: A review. Journal of Drug Delivery Science and Technology 60, pages 102082.
Crossref
Jai B. Sharma, Shailendra Bhatt, Asmita Sharma & Manish Kumar. (2020) Recent Advances in Curcumin Nanocarriers for the Treatment of Different Types of Cancer with Special Emphasis on In Vitro Cytotoxicity and Cellular Uptake Studies. Nanoscience & Nanotechnology-Asia 10:5, pages 577-590.
Crossref
Naseem Akhtar, Salman A.A. Mohammed, Riaz A. Khan, Mohammad Yusuf, Varsha Singh, Hamdoon A. Mohammed, Mohsen S. Al-Omar, Ahmed A.H. Abdellatif, Mamuna Naz & Habeeb Khadri. (2020) Self-Generating nano-emulsification techniques for alternatively-routed, bioavailability enhanced delivery, especially for anti-cancers, anti-diabetics, and miscellaneous drugs of natural, and synthetic origins. Journal of Drug Delivery Science and Technology 58, pages 101808.
Crossref
Agata Pucek, Beata Tokarek, Ewelina Waglewska & Urszula Bazylińska. (2020) Recent Advances in the Structural Design of Photosensitive Agent Formulations Using “Soft” Colloidal Nanocarriers. Pharmaceutics 12:6, pages 587.
Crossref
Delaram Babadi, Simin Dadashzadeh, Mahraz Osouli, Maryam Sadat Daryabari & Azadeh Haeri. (2020) Nanoformulation strategies for improving intestinal permeability of drugs: A more precise look at permeability assessment methods and pharmacokinetic properties changes. Journal of Controlled Release 321, pages 669-709.
Crossref
Hong Wang, Jianchun Luo, Yonghong Zhang, Dan He, Rong Jiang, Xuemei Xie, Qiang Yang, Kailing Li, Jiaxi Xie & Jingqing Zhang. (2020) Phospholipid/hydroxypropyl-β-cyclodextrin supramolecular complexes are promising candidates for efficient oral delivery of curcuminoids. International Journal of Pharmaceutics 582, pages 119301.
Crossref
Wenling Fan, Wenjing Zhu, Xinyi Zhang & Liuqing Di. (2020) The Preparation of Curcumin Sustained-Release Solid Dispersion by Hot Melt Extrusion—Ⅰ. Optimization of the Formulation. Journal of Pharmaceutical Sciences 109:3, pages 1242-1252.
Crossref
Prateek Mathur, Shruti Rawal, Bhoomika Patel & Mayur M. Patel. (2020) Oral Delivery of Anticancer Agents Using Nanoparticulate Drug Delivery System. Current Drug Metabolism 20:14, pages 1132-1140.
Crossref
Luana Izzo, Luigi Castaldo, Alfonso Narváez, Giulia Graziani, Anna Gaspari, Yelko Rodríguez-Carrasco & Alberto Ritieni. (2020) Analysis of Phenolic Compounds in Commercial Cannabis sativa L. Inflorescences Using UHPLC-Q-Orbitrap HRMS. Molecules 25:3, pages 631.
Crossref
Simona Piccolella, Giuseppina Crescente, Lorenzo Candela & Severina Pacifico. (2019) Nutraceutical polyphenols: New analytical challenges and opportunities. Journal of Pharmaceutical and Biomedical Analysis 175, pages 112774.
Crossref
Li Li, Chun Hui Zhou & Zhi Ping Xu. 2019. Nanocarriers for Drug Delivery. Nanocarriers for Drug Delivery 421 449 .
Yi‐Shiou Chiou, Shiming Li, Chi‐Tang Ho & Min‐Hsiung Pan. (2018) Prevention of Breast Cancer by Natural Phytochemicals: Focusing on Molecular Targets and Combinational Strategy. Molecular Nutrition & Food Research 62:23.
Crossref
Khaled AboulFotouh, Ayat A Allam, Mahmoud El-Badry & Ahmed M El-Sayed. (2018) Self-emulsifying drug–delivery systems modulate P-glycoprotein activity: role of excipients and formulation aspects. Nanomedicine 13:14, pages 1813-1834.
Crossref
Bijay Kumar GuptaShobhit KumarHarleen KaurJaved AliSanjula Baboota. (2018) Attenuation of Oxidative Damage by Coenzyme Q 10 Loaded Nanoemulsion Through Oral Route for the Management of Parkinson's Disease . Rejuvenation Research 21:3, pages 232-248.
Crossref
Saad M. Alshahrani, Abdullah S. Alshetaili, Ahmed Alalaiwe, Bader B. Alsulays, Md. Khalid Anwer, Ramadan Al-Shdefat, Faisal Imam & Faiyaz Shakeel. (2017) Anticancer Efficacy of Self-Nanoemulsifying Drug Delivery System of Sunitinib Malate. AAPS PharmSciTech 19:1, pages 123-133.
Crossref
Hira Choudhury, Bapi Gorain, Thiagarajan Madheswaran, Manisha Pandey, Prashant Kesharwani & Rakesh K. Tekade. 2018. Dosage Form Design Considerations. Dosage Form Design Considerations 473 512 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.