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Research Articles

Co-milled API-lactose systems for inhalation therapy: impact of magnesium stearate on physico-chemical stability and aerosolization performance

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Pages 980-988 | Received 27 Sep 2016, Accepted 24 Jan 2017, Published online: 09 Feb 2017

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Rachel Yoon Kyung Chang, Lan Chen, Donghao Chen & Hak-Kim Chan. (2020) Overcoming challenges for development of amorphous powders for inhalation. Expert Opinion on Drug Delivery 17:11, pages 1583-1595.
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Articles from other publishers (16)

Sabrina Magramane, Kristina Vlahović, Péter Gordon, Nikolett Kállai-Szabó, Romána Zelkó, István Antal & Dóra Farkas. (2023) Inhalation Dosage Forms: A Focus on Dry Powder Inhalers and Their Advancements. Pharmaceuticals 16:12, pages 1658.
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Qingzhen Zhang, Shanglong Kou, Yingtong Cui, Jie Dong, Yuqing Ye, Yuanyuan Wang, Rui Lu, Xinduo Li, Yi Nie, Kaiqi Shi, Fang Chen, Philip Hall, Xiaoling Chen, Zheng Wang & Xingtao Jiang. (2023) Ternary Dry Powder Agglomerate Inhalation Formulation of Melatonin With Air Jet Mixing to Improve In Vitro And In Vivo Performance. Journal of Pharmaceutical Sciences.
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Min-Seok Yang, Ji-Hyun Kang, Dong-Wook Kim & Chun-Woong Park. (2023) Recent developments in dry powder inhalation (DPI) formulations for lung-targeted drug delivery. Journal of Pharmaceutical Investigation.
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Rachel Yoon Kyung Chang & Hak-Kim Chan. (2022) Advancements in Particle Engineering for Inhalation Delivery of Small Molecules and Biotherapeutics. Pharmaceutical Research 39:12, pages 3047-3061.
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Riya Mahar, Arpita Chakraborty & Nidhi Nainwal. (2022) The influence of carrier type, physical characteristics, and blending techniques on the performance of dry powder inhalers. Journal of Drug Delivery Science and Technology 76, pages 103759.
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Gerald A. Hebbink, Maarten Jaspers, Harry J.W. Peters & Bastiaan H.J. Dickhoff. (2022) Recent developments in lactose blend formulations for carrier-based dry powder inhalation. Advanced Drug Delivery Reviews 189, pages 114527.
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Yoen-Ju Son, Danforth P. Miller & Jeffry G. Weers. (2021) Optimizing Spray-Dried Porous Particles for High Dose Delivery with a Portable Dry Powder Inhaler. Pharmaceutics 13:9, pages 1528.
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Daniel P. Dobson, Evelyn Yanez, Joseph W. Lubach, Andreas Stumpf, Jackson Pellet & Jerry Tso. (2021) Utilizing Solid-State Techniques and Accelerated Conditions to Understand Particle Size Instability in Inhaled Drug Substances. Journal of Pharmaceutical Sciences 110:8, pages 3037-3046.
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Edit Benke, Patrícia Varga, Piroska Szabó-Révész & Rita Ambrus. (2021) Stability and In Vitro Aerodynamic Studies of Inhalation Powders Containing Ciprofloxacin Hydrochloride Applying Different DPI Capsule Types. Pharmaceutics 13:5, pages 689.
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Anne Haaije de Boer & Kyrre Thalberg. 2021. Inhaled Medicines. Inhaled Medicines 99 146 .
Edit Benke, Árpád Farkas, Piroska Szabó-Révész & Rita Ambrus. (2020) Development of an Innovative, Carrier-Based Dry Powder Inhalation Formulation Containing Spray-Dried Meloxicam Potassium to Improve the In Vitro and In Silico Aerodynamic Properties. Pharmaceutics 12:6, pages 535.
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Junhong Ling, Sharad Mangal, Heejun Park, Shaoning Wang, Alex Cavallaro & Qi Tony Zhou. (2019) Simultaneous Particle Size Reduction and Homogeneous Mixing to Produce Combinational Powder Formulations for Inhalation by the Single-Step Co-Jet Milling. Journal of Pharmaceutical Sciences 108:9, pages 3146-3151.
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Sharad Mangal, Heejun Park, Reham Nour, Nivedita Shetty, Alex Cavallaro, Dmitry Zemlyanov, Kyrre Thalberg, Vibha Puri, Mark Nicholas, Ajit S. Narang & Qi (Tony) Zhou. (2019) Correlations between surface composition and aerosolization of jet-milled dry powder inhaler formulations with pharmaceutical lubricants. International Journal of Pharmaceutics 568, pages 118504.
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Liang Chen, Xiaoyi Ding, Zizhou He, Siqi Fan, Kuriakose T. Kunnath, Kai Zheng & Rajesh N. Davé. (2018) Surface engineered excipients: II. Simultaneous milling and dry coating for preparation of fine-grade microcrystalline cellulose with enhanced properties. International Journal of Pharmaceutics 546:1-2, pages 125-136.
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Jiaqi Yu, Maria-Cristina Romeo, Alex A. Cavallaro & Hak-Kim Chan. (2018) Protective effect of sodium stearate on the moisture-induced deterioration of hygroscopic spray-dried powders. International Journal of Pharmaceutics 541:1-2, pages 11-18.
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M.W. Jetzer, B.D. Morrical, M. Schneider, S. Edge & G. Imanidis. (2018) Probing the particulate microstructure of the aerodynamic particle size distribution of dry powder inhaler combination products. International Journal of Pharmaceutics 538:1-2, pages 30-39.
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