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Research Articles

Amorphous nanoparticle complex of perphenazine and dextran sulfate as a new solubility enhancement strategy of antipsychotic perphenazine

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Pages 996-1002 | Received 25 Oct 2016, Accepted 24 Jan 2017, Published online: 13 Feb 2017

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Zahra Saghafi, Mojdeh Mohammadi, Mohammad Mehdi Mahboobian & Katayoun Derakhshandeh. (2021) Preparation, characterization, and in vivo evaluation of perphenazine-loaded nanostructured lipid carriers for oral bioavailability improvement. Drug Development and Industrial Pharmacy 47:3, pages 509-520.
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Sultan Alshehri, Faiyaz Shakeel, Ehab Elzayat, Osaid Almeanazel, Mohammad Altamimi, Gamal Shazly, Mohsin Kazi, Bjad Almutairy, Bader Alsulays, Abdullah Alshetaili, Ahmed Alalaiwe & Michael Repka. (2019) Rat palatability, pharmacodynamics effect and bioavailability of mefenamic acid formulations utilizing hot-melt extrusion technology. Drug Development and Industrial Pharmacy 45:10, pages 1610-1616.
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Hong Yu, Li Ming Lim, Bingxue Dong & Kunn Hadinoto. (2019) Proof-of-concept preparation and characterization of dual-drug amorphous nanoparticle complex as fixed-dose combination of poorly soluble drugs. Drug Development and Industrial Pharmacy 45:1, pages 105-116.
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Qandeel Khalid, Mahmood Ahmad & Muhammad Usman Minhas. (2017) Synthesis of β-cyclodextrin hydrogel nanoparticles for improving the solubility of dexibuprofen: characterization and toxicity evaluation. Drug Development and Industrial Pharmacy 43:11, pages 1873-1884.
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Articles from other publishers (11)

Héctor J. Prado, María C. Matulewicz & Marina Ciancia. 2023. Advanced Pharmacy. Advanced Pharmacy 135 196 .
Santiago E. Herrera, Maximiliano L. Agazzi, Eugenia Apuzzo, M. Lorena Cortez, Waldemar A. Marmisollé, Mario Tagliazucchi & Omar Azzaroni. (2023) Polyelectrolyte-multivalent molecule complexes: physicochemical properties and applications. Soft Matter 19:11, pages 2013-2041.
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Saima Asghar, Naveed Akhtar, Muhammad Usman Minhas & Kifayat Ullah Khan. (2021) Bi-polymeric Spongy Matrices Through Cross-linking Polymerization: Synthesized and Evaluated for Solubility Enhancement of Acyclovir. AAPS PharmSciTech 22:5.
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Soni Mishra & Abhishek Kumar Mishra. (2021) Raman microspectroscopic and quantum chemical investigations of neuroleptic drugs interactions with dipalmitoylphosphatidylcholine (DPPC) lipid. Vibrational Spectroscopy 114, pages 103242.
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Parisa Abbasi Farsani, Reza Mahjub, Mojdeh Mohammadi, Seyed Sajad Oliaei & Mohammad Mehdi Mahboobian. (2021) Development of Perphenazine-Loaded Solid Lipid Nanoparticles: Statistical Optimization and Cytotoxicity Studies. BioMed Research International 2021, pages 1-14.
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Allan Radaic & Daniel Martins-de-Souza. (2020) The state of the art of nanopsychiatry for schizophrenia diagnostics and treatment. Nanomedicine: Nanotechnology, Biology and Medicine 28, pages 102222.
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Li Ming Lim & Kunn Hadinoto. (2020) Enhancing the stability of amorphous drug-polyelectrolyte nanoparticle complex using a secondary small-molecule drug as the stabilizer: A case study of ibuprofen-stabilized curcumin-chitosan nanoplex. International Journal of Pharmaceutics 575, pages 119007.
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Bingxue Dong & Kunn Hadinoto. (2019) Carboxymethyl cellulose is a superior polyanion to dextran sulfate in stabilizing and enhancing the solubility of amorphous drug-polyelectrolyte nanoparticle complex. International Journal of Biological Macromolecules 139, pages 500-508.
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Bingxue Dong, Li Ming Lim & Kunn Hadinoto. (2019) Enhancing the physical stability and supersaturation generation of amorphous drug-polyelectrolyte nanoparticle complex via incorporation of crystallization inhibitor at the nanoparticle formation step: A case of HPMC versus PVP. European Journal of Pharmaceutical Sciences 138, pages 105035.
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Ali Ubeyitogullari & Ozan N. Ciftci. (2017) Generating phytosterol nanoparticles in nanoporous bioaerogels via supercritical carbon dioxide impregnation: Effect of impregnation conditions. Journal of Food Engineering 207, pages 99-107.
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Sultan Alshehri, Faiyaz Shakeel, Mohamed Ibrahim, Ehab Elzayat, Mohammad Altamimi, Gamal Shazly, Kazi Mohsin, Musaed Alkholief, Bader Alsulays, Abdullah Alshetaili, Abdulaziz Alshahrani, Bander Almalki & Fars Alanazi. (2017) Influence of the microwave technology on solid dispersions of mefenamic acid and flufenamic acid. PLOS ONE 12:7, pages e0182011.
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