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Drug Development and Industrial Pharmacy Volume 43, 2017 - Issue 8
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Review Article

A review of co-milling techniques for the production of high dose dry powder inhaler formulation

Michael LauThe Woolcock Institute for Medical Research and Discipline of Pharmacology, Sydney Medical School, University of Sydney, Sydney, Australia
,
Paul M. YoungThe Woolcock Institute for Medical Research and Discipline of Pharmacology, Sydney Medical School, University of Sydney, Sydney, Australia
&
Daniela TrainiThe Woolcock Institute for Medical Research and Discipline of Pharmacology, Sydney Medical School, University of Sydney, Sydney, AustraliaCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-7173-017X
ORCID Icon
Pages 1229-1238 | Received 21 Oct 2016, Accepted 23 Mar 2017, Published online: 19 Apr 2017

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Junqi Wu, Sawnaz Shaidani, Sophia K. Theodossiou, Emily J. Hartzell & David L. Kaplan. (2022) Localized, on-demand, sustained drug delivery from biopolymer-based materials. Expert Opinion on Drug Delivery 19:10, pages 1317-1335.
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Bishal Raj Adhikari, Jack Dummer, Keith C. Gordon & Shyamal C. Das. (2022) An expert opinion on respiratory delivery of high dose powders for lung infections. Expert Opinion on Drug Delivery 19:7, pages 795-813.
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Ashlee D. Brunaugh, Shivam Sharma & Hugh Smyth. (2021) Inhaled fixed-dose combination powders for the treatment of respiratory infections. Expert Opinion on Drug Delivery 18:8, pages 1101-1115.
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Nivedita Shetty, David Cipolla, Heejun Park & Qi Tony Zhou. (2020) Physical stability of dry powder inhaler formulations. Expert Opinion on Drug Delivery 17:1, pages 77-96.
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Articles from other publishers (20)

Min-Seok Yang, Ji-Hyun Kang, Dong-Wook Kim & Chun-Woong Park. (2023) Recent developments in dry powder inhalation (DPI) formulations for lung-targeted drug delivery. Journal of Pharmaceutical Investigation.
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Fidel Méndez Cañellas, Noor Al-Rifai, Luis Padrela, Lidia Tajber, Tatsiana Khamiakova, Martin Otava & Robert Geertman. (2023) A comparative study of dry and wet top-down milling approaches for the preparation of microparticle suspensions. Powder Technology 428, pages 118829.
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Dongli Qi, Bei Jia, Hui Peng, Jiachen He, Jiaxin Pi, Pan Guo, Ying Zhang, Xiuping Deng, Jiawei Li & Zhidong Liu. (2023) Baicalin/ambroxol hydrochloride combined dry powder inhalation formulation targeting lung delivery for treatment of idiopathic pulmonary fibrosis: Fabrication, characterization, pharmacokinetics, and pharmacodynamics. European Journal of Pharmaceutics and Biopharmaceutics 188, pages 243-253.
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Jae-Cheol Choi, Ji-Hyun Kang, Dong-Wook Kim & Chun-Woong Park. (2023) Preparation and Evaluation of Inhalable Amifostine Microparticles Using Wet Ball Milling. Pharmaceutics 15:6, pages 1696.
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Piyush Pradeep Mehta & Vividha Dhapte-Pawar. 2023. Pulmonary Drug Delivery Systems: Material and Technological Advances. Pulmonary Drug Delivery Systems: Material and Technological Advances 1 44 .
Bishal Raj Adhikari, Keith C. Gordon & Shyamal C. Das. (2022) Solid state of inhalable high dose powders. Advanced Drug Delivery Reviews 189, pages 114468.
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Nicholas Bungert, Mirjam Kobler & Regina Scherließ. (2022) Proof-of-Concept for Adjusted Surface Energies and Modified Fines as a Novel Concept in Particle Engineering for DPI Formulations. Pharmaceutics 14:5, pages 951.
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Bishal Raj Adhikari, Kārlis Bērziņš, Sara J. Fraser-Miller, Alex Cavallaro, Keith C. Gordon & Shyamal C. Das. (2022) Optimization of methionine in inhalable High-dose Spray-dried amorphous composite particles using response surface Method, infrared and low frequency Raman spectroscopy. International Journal of Pharmaceutics 614, pages 121446.
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Dipesh Khanal, Wei-Ren Ke & Hak-Kim Chan. (2022) Raman spectroscopic evaluation of crystallinity, chemical composition and stability of pharmaceutical powder aerosols. International Journal of Pharmaceutics 611, pages 121341.
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Gauri Shadambikar, Sushrut Marathe, Nan Ji, Mashan Almutairi, Suresh Bandari, Feng Zhang, Mahavir Chougule & Michael Repka. (2021) Formulation development of itraconazole PEGylated nano-lipid carriers for pulmonary aspergillosis using hot-melt extrusion technology. International Journal of Pharmaceutics: X 3, pages 100074.
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Heejun Park, Eun-Sol Ha & Min-Soo Kim. (2021) Surface modification strategies for high-dose dry powder inhalers. Journal of Pharmaceutical Investigation 51:6, pages 635-668.
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Yoen-Ju Son, Danforth P. Miller & Jeffry G. Weers. (2021) Optimizing Spray-Dried Porous Particles for High Dose Delivery with a Portable Dry Powder Inhaler. Pharmaceutics 13:9, pages 1528.
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Ahmed H. AlbariqiRachel Yoon Kyung ChangWaiting TaiWei-Ren KeMichael Y.T. ChowPatricia TangPhilip Chi Lip KwokHak-Kim Chan. (2021) Inhalable Hydroxychloroquine Powders for Potential Treatment of COVID-19. Journal of Aerosol Medicine and Pulmonary Drug Delivery 34:1, pages 20-31.
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Khaled AboulFotouh, Yi Zhang, Mohammed Maniruzzaman, Robert O. WilliamsIIIIII & Zhengrong Cui. (2020) Amorphous solid dispersion dry powder for pulmonary drug delivery: Advantages and challenges. International Journal of Pharmaceutics 587, pages 119711.
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Mahasweta Paul & Raymond Lau. (2020) Potentials and challenges of Levodopa particle formulation for treatment of Parkinson’s disease through intranasal and pulmonary delivery. Advanced Powder Technology 31:6, pages 2357-2365.
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Vibha Puri, Jagdeep ShurAjit S. Narang. (2019) Elucidating Molecular- and Particle-Level Changes during the Annealing of a Micronized Crystalline Drug. Molecular Pharmaceutics 16:10, pages 4339-4351.
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Junhong Ling, Sharad Mangal, Heejun Park, Shaoning Wang, Alex Cavallaro & Qi Tony Zhou. (2019) Simultaneous Particle Size Reduction and Homogeneous Mixing to Produce Combinational Powder Formulations for Inhalation by the Single-Step Co-Jet Milling. Journal of Pharmaceutical Sciences 108:9, pages 3146-3151.
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Sharad Mangal, Heejun Park, Reham Nour, Nivedita Shetty, Alex Cavallaro, Dmitry Zemlyanov, Kyrre Thalberg, Vibha Puri, Mark Nicholas, Ajit S. Narang & Qi (Tony) Zhou. (2019) Correlations between surface composition and aerosolization of jet-milled dry powder inhaler formulations with pharmaceutical lubricants. International Journal of Pharmaceutics 568, pages 118504.
Crossref
Mohammad A.M. Momin, Ian G. Tucker & Shyamal C. Das. (2018) High dose dry powder inhalers to overcome the challenges of tuberculosis treatment. International Journal of Pharmaceutics 550:1-2, pages 398-417.
Crossref
Regina Scherließ & Christian Etschmann. (2018) DPI formulations for high dose applications – Challenges and opportunities. International Journal of Pharmaceutics 548:1, pages 49-53.
Crossref

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