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Research Article

Microemulsion loaded hydrogel as a promising vehicle for dermal delivery of the antifungal sertaconazole: design, optimization and ex vivo evaluation

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Pages 1351-1365 | Received 08 Oct 2016, Accepted 03 Apr 2017, Published online: 27 Apr 2017

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Noha M. Badawi, Rania M. Yehia, Caroline Lamie, Khaled A. Abdelrahman, Dalia A. Attia & Doaa A. Helal. (2023) Tackling acne vulgaris by fabrication of tazarotene-loaded essential oil-based microemulsion: In vitro and in vivo evaluation. International Journal of Pharmaceutics: X 5, pages 100185.
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Panoraia I. Siafaka, Evren Atlıhan Gündoğdu, Emre Sefik Cağlar, Emre Özgenç, Marta Gonzalez-Alvarez, Isabel Gonzalez-Alvarez & Neslihan Üstündağ Okur. (2023) Polymer based Gels: Recent and Future Applications in Drug Delivery Field. Current Drug Delivery 20:9, pages 1288-1313.
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Nihal Farid Younes & Basant Ahmed Habib. (2022) Augmented local skin accumulation efficiency of sertaconazole nitrate via glycerosomal hydrogel: Formulation, statistical optimization, ex vivo performance and in vivo penetration. Journal of Drug Delivery Science and Technology 72, pages 103364.
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Mahshid Daryab, Mehrdad Faizi, Arash Mahboubi & Reza Aboofazeli. (2022) Preparation and Characterization of Lidocaine-Loaded, Microemulsion-Based Topical Gels. Iranian Journal of Pharmaceutical Research 21:1.
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Hoang Vu Dang, Hung Tran Huu & Hue Minh Thi Nguyen. (2021) Investigating the influence of excipient batch variation on the structure, consistency and physical stability of polysorbate 60–based topical vehicles. International Journal of Cosmetic Science 43:6, pages 715-728.
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Mai El Halawany, Randa Latif & Alia Badawi. (2021) The Potential of a Site-Specific Delivery of Thiamine Hydrochloride as a Novel Insect Repellent Exerting Long-Term Protection on Human Skin: In-vitro, Ex-vivo Study and Clinical Assessment. Journal of Pharmaceutical Sciences 110:11, pages 3659-3669.
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Cristina da Costa Bernardes Araújo, Alice Simon, Thiago da Silva Honório, Silvia Valéria Cruz da Silva, Isabella Mourão Machado Valle, Luiz Cláudio Rodrigues Pereira da Silva, Carlos Rangel Rodrigues, Valeria Pereira de Sousa, Lucio Mendes Cabral, Plínio Cunha Sathler & Flávia Almada do Carmo. (2021) Development of rivaroxaban microemulsion-based hydrogel for transdermal treatment and prevention of venous thromboembolism. Colloids and Surfaces B: Biointerfaces 206, pages 111978.
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Nataša Bubić Pajić, Sonja Vucen, Tanja Ilić, Conor O'Mahony, Vladimir Dobričić & Snežana Savić. (2021) Comparative efficacy evaluation of different penetration enhancement strategies for dermal delivery of poorly soluble drugs – A case with sertaconazole nitrate. European Journal of Pharmaceutical Sciences 164, pages 105895.
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Shweta Nene, Saurabh Shah, Nagarjun Rangaraj, Neelesh Kumar Mehra, Pankaj Kumar Singh & Saurabh Srivastava. (2021) Lipid based nanocarriers: A novel paradigm for topical antifungal therapy. Journal of Drug Delivery Science and Technology 62, pages 102397.
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Sevgi Güngör & Emine Kahraman. (2021) Nanocarriers Mediated Cutaneous Drug Delivery. European Journal of Pharmaceutical Sciences 158, pages 105638.
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Ioanna Theochari, Tanja Ilic, Ines Nicolic, Vladimir Dobricic, Alia Tenchiou, Demetris Papahatjis, Snezana Savic, Aristotelis Xenakis, Vassiliki Papadimitriou & Vasiliki Pletsa. (2021) Biological Evaluation of Oil-in-Water Microemulsions as Carriers of Benzothiophene Analogues for Dermal Applications. Biomimetics 6:1, pages 10.
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Nishtha Chaurawal & Kaisar Raza. 2021. Design of Experiments for Pharmaceutical Product Development. Design of Experiments for Pharmaceutical Product Development 27 56 .
Aditee Ghose, Bushra Nabi, Saleha Rehman, Shadab Md, Nabil A. Alhakamy, Osama A. A. Ahmad, Sanjula Baboota & Javed Ali. (2020) Development and Evaluation of Polymeric Nanosponge Hydrogel for Terbinafine Hydrochloride: Statistical Optimization, In Vitro and In Vivo Studies. Polymers 12:12, pages 2903.
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Farzana Anjum, Foziyah Zakir, Devina Verma, Mohd Aqil, Manvi Singh, Pooja Jain, Mohd Aamir Mirza, Md. Khalid Anwer & Zeenat Iqbal. (2020) Exploration of Nanoethosomal Transgel of Naproxen Sodium for the Treatment of Arthritis. Current Drug Delivery 17:10, pages 885-897.
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Shammy Jindal, Rajendra Awasthi, Dhananjay Singhare & Giriraj T. Kulkarni. (2020) Topical delivery of Tacrolimus using liposome containing gel: An emerging and synergistic approach in management of psoriasis. Medical Hypotheses 142, pages 109838.
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Shaimaa Ali Ali Radwan, Walaa H. El-Maadawy, Aliaa Nabil ElMeshad, Raguia Aly Shoukri & Carol Yousry. (2020) Impact of Reverse Micelle Loaded Lipid Nanocapsules on the Delivery of Gallic Acid into Activated Hepatic Stellate Cells: A Promising Therapeutic Approach for Hepatic Fibrosis. Pharmaceutical Research 37:9.
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Abhinava Garg, Ganti S. Sharma, Amit K. Goyal, Goutam Ghosh, Sudam Chandra Si & Goutam Rath. (2020) Recent advances in topical carriers of anti-fungal agents. Heliyon 6:8, pages e04663.
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Mohamed Moustafa Ibrahim, Doaa Nabih Maria, XiangDi Wang, Raven N. Simpson, T.J. Hollingsworth & Monica M. Jablonski. (2020) Enhanced Corneal Penetration of a Poorly Permeable Drug Using Bioadhesive Multiple Microemulsion Technology. Pharmaceutics 12:8, pages 704.
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Carol Yousry, Pakinam Mohsen ZikryEmad Basalious BasaliousOmaima Naem El-Gazayerly. (2020) Self-nanoemulsifying System Optimization for Higher Terconazole Solubilization and Non-Irritant Ocular Administration. Advanced Pharmaceutical Bulletin 10:3, pages 389-398.
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Ioanna Theochari, Aristotelis Xenakis & Vassiliki Papadimitriou. 2020. Smart Nanocontainers. Smart Nanocontainers 315 341 .
Menna Assem, Omneya Mohammed Khowessah & Dalia Ghorab. (2019) Nano-crystallization as a tool for the enhancement of beclomethasone dipropionate dermal deposition: Formulation, in vitro characterization and ex vivo study. Journal of Drug Delivery Science and Technology 54, pages 101318.
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Menna Assem, Omneya Mohammed Khowessah & Dalia Ghorab. (2019) Optimization and Evaluation of Beclomethasone Dipropionate Micelles Incorporated into Biocompatible Hydrogel Using a Sub-Chronic Dermatitis Animal Model. AAPS PharmSciTech 20:4.
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Sadaf Jamal Gilani, Md. Rizwanullah, Syed Sarim Imam, Jayamanti Pandit, Mohd. Aqil, Meraj Alam & Sarwar Beg. 2019. Pharmaceutical Quality by Design. Pharmaceutical Quality by Design 131 150 .
Natasa Bubic Pajic, Ines Nikolic, Evgenia Mitsou, Vassiliki Papadimitriou, Aristotelis Xenakis, Danijela Randjelovic, Vladimir Dobricic, Aleksandra Smitran, Nebojsa Cekic, Bojan Calija & Snezana Savic. (2018) Biocompatible microemulsions for improved dermal delivery of sertaconazole nitrate: Phase behavior study and microstructure influence on drug biopharamaceutical properties. Journal of Molecular Liquids 272, pages 746-758.
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Moammal S. Qurt, İmren Esentürk, Seher Birteksöz Tan, Meryem Sedef Erdal, Ahmet Araman & Sevgi Güngör. (2018) Voriconazole and sertaconazole loaded colloidal nano-carriers for enhanced skin deposition and improved topical fungal treatment. Journal of Drug Delivery Science and Technology 48, pages 215-222.
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Mohamed Ahmed Naseef, Howida Kamal Ibrahim & Samia Abd El-Kader Nour. (2018) Solid Form of Lipid-Based Self-Nanoemulsifying Drug Delivery Systems for Minimization of Diacerein Adverse Effects: Development and Bioequivalence Evaluation in Albino Rabbits. AAPS PharmSciTech 19:7, pages 3097-3109.
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