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Drug Development and Industrial Pharmacy Volume 43, 2017 - Issue 11
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Research Article

Biodegradable nanoparticles for improved kidney bioavailability of rhein: preparation, characterization, plasma, and kidney pharmacokinetics

Yinghui WeiCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, ChinaCorrespondence[email protected]
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Xiaoting LuoCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, ChinaView further author information
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Jiani GuanCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, ChinaView further author information
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Jianping MaCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, ChinaView further author information
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Yicong ZhongCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, ChinaView further author information
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Jingwen LuoCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, ChinaView further author information
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Fanzhu LiCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, ChinaView further author information
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Pages 1885-1891 | Received 15 Oct 2016, Accepted 03 Jul 2017, Published online: 26 Jul 2017

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Danfei Chen, Shunping Han, Yongqin Zhu, Fang Hu, Yinghui Wei & Guowei Wang. (2018) Kidney-targeted drug delivery via rhein-loaded polyethyleneglycol-co-polycaprolactone-co-polyethylenimine nanoparticles for diabetic nephropathy therapy. International Journal of Nanomedicine 13, pages 3507-3527.
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Articles from other publishers (13)

Shengjun Peng, Yizhou Wang, Zhifang Sun, Laien Zhao, Yanmei Huang, Xiaoxuan Fu, Rongrui Luo, Jianyue Xue, Shubin Yang, Longbing Ling & Zhuhong Zhang. (2023) Nanoparticles loaded with pharmacologically active plant-derived natural products: Biomedical applications and toxicity. Colloids and Surfaces B: Biointerfaces 225, pages 113214.
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Javier Avendaño-Godoy, Maria Gabriela Poblete, Ricardo Godoy Ramos & Carolina Gómez-Gaete. (2023) Evaluation of the Effects of Gamma Radiation Sterilization on Rhein-Loaded Biodegradable Microparticles for the Treatment of Osteoarthritis. Journal of Pharmaceutical Sciences 112:3, pages 837-843.
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Hongjuan Wang, Dezhi Yang, Wen Zhang, Junke Song, Ningbo Gong, Mingchao Yu, Shiying Yang, Baoxi Zhang, Qiwen Liu, Guanhua Du & Yang Lu. (2023) An innovative rhein-matrine cocrystal: Synthesis, characterization, formation mechanism and pharmacokinetic study. Chinese Chemical Letters 34:2, pages 107258.
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Tingting Deng, Jinxin Du, Ying Yin, Baorui Cao, Zhiying Wang, Zhongwen Zhang, Meina Yang & Jinxiang Han. (2023) Rhein for treating diabetes mellitus: A pharmacological and mechanistic overview. Frontiers in Pharmacology 13.
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Shanshan Qi, Ruifeng Luo, Xiaoqin Han, Wenbiao Nie, Naijing Ye, Chaomei Fu & Fei Gao. (2022) pH/ROS Dual-Sensitive Natural Polysaccharide Nanoparticles Enhance “One Stone Four Birds” Effect of Rhein on Ulcerative Colitis. ACS Applied Materials & Interfaces 14:45, pages 50692-50709.
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Ruifeng Luo, Meisi Lin, Chaomei Fu, Jinming Zhang, Qiyan Chen, Chen Zhang, Jinfeng Shi, Xiulan Pu, Linlin Dong, Haiting Xu, Naijing Ye, Jiayi Sun, Dasheng Lin, Bin Deng, Arlene McDowell, Shu Fu & Fei Gao. (2021) Calcium pectinate and hyaluronic acid modified lactoferrin nanoparticles loaded rhein with dual-targeting for ulcerative colitis treatment. Carbohydrate Polymers 263, pages 117998.
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Qiyan Chen, Ruifeng Luo, Xiaoqin Han, Jinming Zhang, Yao He, Shanshan Qi, Xiulan Pu, Wenbiao Nie, Lingling Dong, Haiting Xu, Fang Liu, Meisi Lin, Huiyun Zhong, Chaomei Fu & Fei Gao. (2021) Entrapment of Macrophage-Target Nanoparticles by Yeast Microparticles for Rhein Delivery in Ulcerative Colitis Treatment. Biomacromolecules 22:6, pages 2754-2767.
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R.J.A. Vibhavari, Gautam Kumar, Vanishree Rao, Sri Pragnya Cheruku & Nitesh Kumar. 2021. Nano-Pharmacokinetics and Theranostics. Nano-Pharmacokinetics and Theranostics 117 152 .
Shun-Li Xiao, Liang-Jun Guan, Ren-Feng Jiang, Xiang-Gen Wang, Xing Li & Wei Cai. (2020) The Metabolism and Pharmacokinetics of Rhein and Aurantio-Obtusin. Current Drug Metabolism 21:12, pages 960-968.
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Li Qiao, Maosen Han, Shijie Gao, Xinxin Shao, Xiaoming Wang, Linlin Sun, Xianjun Fu & Qingcong Wei. (2020) Research progress on nanotechnology for delivery of active ingredients from traditional Chinese medicines. Journal of Materials Chemistry B 8:30, pages 6333-6351.
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Liqing Chen, Atef Mohammed Qasem Ahmed, Yibin Deng, Dingyun Cao, Huanhuan Du, Jinghao Cui, Beom-Jin Lee & Qingri Cao. (2019) Novel triptorelin acetate-loaded microspheres prepared by a liquid/oil/oil method with high encapsulation efficiency and low initial burst release. Journal of Drug Delivery Science and Technology 54, pages 101390.
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Jatinder Kaur Mukker & Ravi Shankar Prasad Singh. (2019) Pharmacokinetic Modeling in Nano-formulations: Concept, Implementation and Challenges. Current Pharmaceutical Design 24:43, pages 5175-5180.
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Yanchun Wei, Li Quan, Chao Zhou & Qiuqiang Zhan. (2018) Factors relating to the biodistribution & clearance of nanoparticles & their effects on in vivo application . Nanomedicine 13:12, pages 1495-1512.
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