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Drug Development and Industrial Pharmacy Volume 44, 2018 - Issue 4
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Research Article

Development of optimized self-nanoemulsifying lyophilized tablets (SNELTs) to improve finasteride clinical pharmacokinetic behavior

Tarek A. AhmedDepartment of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia; ;Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt; Correspondence[email protected] [email protected]
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Khalid M. El-SayDepartment of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia; ;Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt; View further author information
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Khaled M. HosnyDepartment of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia; ;Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, EgyptView further author information
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Bader M. AljaeidDepartment of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia; View further author information
Pages 652-661 | Received 21 Aug 2017, Accepted 12 Nov 2017, Published online: 29 Nov 2017

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Malik Muhammad Irfan, Shefaat Ullah Shah, Ikram Ullah Khan, Muhammad Usman Munir, Nauman Rahim Khan, Kifayat Ullah Shah, Saif Ur Rehman, Muhammad Sohaib, Hafiz Muhammad Basit & Saima Mahmood. (2021) Physicochemical Characterization of Finasteride Nanosystem for Enhanced Topical Delivery. International Journal of Nanomedicine 16, pages 1207-1220.
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Khaled M. Hosny, Nabil A. Alhakamy & Khalid S. Al Nahyah. (2021) The relevance of nanotechnology, hepato-protective agents in reducing the toxicity and augmenting the bioavailability of isotretinoin. Drug Delivery 28:1, pages 115-125.
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Khaled M Hosny. (2019) Development Of Saquinavir Mesylate Nanoemulsion-Loaded Transdermal Films: Two-Step Optimization Of Permeation Parameters, Characterization, And Ex Vivo And In Vivo Evaluation. International Journal of Nanomedicine 14, pages 8589-8601.
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Tarek A Ahmed. (2019) Formulation and clinical investigation of optimized vinpocetine lyoplant-tabs: new strategy in development of buccal solid dosage form. Drug Design, Development and Therapy 13, pages 205-220.
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Articles from other publishers (14)

Saliha Ilyas, Safirah Maheen, Mehwish Andleeb, Hafeez Ullah Khan, Shahid Shah, Ghulam Abbas, Saleha Shabbir, Muhammad Sher, Syeda Amna Masood & Syed Salman Shafqat. (2023) Development, optimization and in vitro-in vivo evaluation of solid lipid microparticles for improved pharmacokinetic profile of bisoprolol. Materials Today Communications 37, pages 107097.
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Piyong Sola, Kusuma Kumari Garikapati, Praveen Thaggikuppe Krishnamurthy & Mamta Kumari. (2023) Polysorbate 80 surface modified SLNs of formoterol suppress SNCA gene and mitochondrial oxidative stress in mice model of Parkinson’s disease. Scientific Reports 13:1.
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Khalid M. El-Say & Tarek A. Ahmed. 2022. The ADME Encyclopedia. The ADME Encyclopedia 222 231 .
Haobing Shi, Yuhong Zheng, Hassan Karimi-Maleh & Li Fu. (2021) Alginate-modified Cassava Fiber Loaded Palladium for Electochemical Paracetamol Analysis. International Journal of Electrochemical Science 16:10, pages 21108.
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Amal M. Sindi, Khaled M. Hosny & Waleed S. Alharbi. (2021) Lyophilized Composite Loaded with Meloxicam-Peppermint oil Nanoemulsion for Periodontal Pain. Polymers 13:14, pages 2317.
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Hossam M. Abdallah, Hany M. El-Bassossy, Ali M. El-Halawany, Tarek A. Ahmed, Gamal A. Mohamed, Azizah M. Malebari & Noura A. Hassan. (2021) Self-Nanoemulsifying Drug Delivery System Loaded with Psiadia punctulata Major Metabolites for Hypertensive Emergencies: Effect on Hemodynamics and Cardiac Conductance. Frontiers in Pharmacology 12.
Crossref
Khalid M. El-Say & Tarek A. Ahmed. 2021. The ADME Encyclopedia. The ADME Encyclopedia 1 10 .
Fayez O. Alotaibi, Nabil A. Alhakamy, Abdelsattar M. Omar & Khalid M. El-Say. (2020) Clinical Pharmacokinetic Evaluation of Optimized Liquisolid Tablets as a Potential Therapy for Male Sexual Dysfunction. Pharmaceutics 12:12, pages 1187.
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Ceyda Tuba Sengel-Turk, Mehmet Eray Alcigir, Okan Ekim, Filiz Bakar-Ates & Canan Hascicek. (2020) Clinicopathological and immunohistochemical evaluation of lonidamine-entrapped lipid–polymer hybrid nanoparticles in treatment of benign prostatic hyperplasia: An experimental rat model. European Journal of Pharmaceutics and Biopharmaceutics 157, pages 211-220.
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Khaled M. Hosny, Nabil A. Alhakamy, Maeen A. Almodhwahi, Mallesh Kurakula, Alshaimaa M. Almehmady & Samar S. Elgebaly. (2020) Self-Nanoemulsifying System Loaded with Sildenafil Citrate and Incorporated within Oral Lyophilized Flash Tablets: Preparation, Optimization, and In Vivo Evaluation. Pharmaceutics 12:11, pages 1124.
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Naseem Akhtar, Salman A.A. Mohammed, Riaz A. Khan, Mohammad Yusuf, Varsha Singh, Hamdoon A. Mohammed, Mohsen S. Al-Omar, Ahmed A.H. Abdellatif, Mamuna Naz & Habeeb Khadri. (2020) Self-Generating nano-emulsification techniques for alternatively-routed, bioavailability enhanced delivery, especially for anti-cancers, anti-diabetics, and miscellaneous drugs of natural, and synthetic origins. Journal of Drug Delivery Science and Technology 58, pages 101808.
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Hanan Elimam, Khalid M. El-Say, Andrey V. Cybulsky & Hany Khalil. (2020) Regulation of Autophagy Progress via Lysosomal Depletion by Fluvastatin Nanoparticle Treatment in Breast Cancer Cells. ACS Omega 5:25, pages 15476-15486.
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Yasir A. Al-Amodi, Khaled M Hosny, Waleed S. Alharbi, Martin K. Safo & Khalid M El-Say. (2020) Investigating the Potential of Transmucosal Delivery of Febuxostat from Oral Lyophilized Tablets Loaded with a Self-Nanoemulsifying Delivery System. Pharmaceutics 12:6, pages 534.
Crossref
Renata Carvalho Feitosa, Danilo Costa Geraldes, Viviane Lucia Beraldo-de-Araújo, Juliana Souza Ribeiro Costa & Laura Oliveira-Nascimento. (2019) Pharmacokinetic Aspects of Nanoparticle-in-Matrix Drug Delivery Systems for Oral/Buccal Delivery. Frontiers in Pharmacology 10.
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