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Drug Development and Industrial Pharmacy Volume 44, 2018 - Issue 6
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Research Article

Enhancement of solubility and bioavailability of ambrisentan by solid dispersion using Daucus carota as a drug carrier: formulation, characterization, in vitro, and in vivo study

Subhash DeshmaneDepartment of Pharmaceutics, Anuradha College of Pharmacy, Chikhli, India; Correspondence[email protected]
,
Snehal DeshmaneDepartment of Pharmaceutics, Anuradha College of Pharmacy, Chikhli, India;
,
Santosh ShelkeDepartment of Pharmaceutics, Yash Institute of Pharmacy, Aurangabad, IndiaORCID Iconhttp://orcid.org/0000-0001-5904-6028
ORCID Icon &
Kailash BiyaniDepartment of Pharmaceutics, Anuradha College of Pharmacy, Chikhli, India;
Pages 1001-1011 | Received 22 Dec 2017, Accepted 11 Jan 2018, Published online: 05 Feb 2018

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Zhongcheng Ke, Jianjun Shi, Ziyang Cheng, Xiaoling Cheng, Huan Wang, Meng Wang, Jingjing Wu, Yinyu Sun & Changjiang Li. (2022) Design and characterization of gambogic acid-loaded mixed micelles system for enhanced oral bioavailability. Pharmaceutical Development and Technology 27:6, pages 695-701.
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Gajanan Shinde, Pankhita Desai, Santosh Shelke, Rakesh Patel, Ganesh Bangale & Deepak Kulkarni. (2022) Mometasone furoate-loaded aspasomal gel for topical treatment of psoriasis: formulation, optimization, in vitro and in vivo performance. Journal of Dermatological Treatment 33:2, pages 885-896.
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Hongfei Liu, Kunyu Du, Dongli Li, Yi Du, Jumei Xi, Ying Xu, Yan Shen, Tao Jiang & Thomas J Webster. (2018) A high bioavailability and sustained-release nano-delivery system for nintedanib based on electrospray technology. International Journal of Nanomedicine 13, pages 8379-8393.
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Hongxue Shen, Dandan He, Shuxia Wang, Pinggang Ding, Jianan Wang & Jianming Ju. (2018) Preparation, characterization, and pharmacokinetics study of a novel genistein-loaded mixed micelles system. Drug Development and Industrial Pharmacy 44:9, pages 1536-1542.
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U. Atneriya, D. Kapoor, J. Sainy & R. Maheshwari. (2023) In vitro profiling of fenofibrate solid dispersion mediated tablet formulation to treat high blood cholesterol. Annales Pharmaceutiques Françaises 81:2, pages 284-299.
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Haidy Abbas, Nesrine S El Sayed, Nancy Abdel Hamid Abou Youssef, Passent M. E. Gaafar, Mohamed R. Mousa, Ahmed M. Fayez & Manal A Elsheikh. (2022) Novel Luteolin-Loaded Chitosan Decorated Nanoparticles for Brain-Targeting Delivery in a Sporadic Alzheimer’s Disease Mouse Model: Focus on Antioxidant, Anti-Inflammatory, and Amyloidogenic Pathways. Pharmaceutics 14:5, pages 1003.
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Lali Ronsoni Zancan, Franciele Aline Bruinsmann, Karine Paese, Patrick Türck, Alan Bahr, Alexsandra Zimmer, Cristina Campos Carraro, Paulo Cavalheiro Schenkel, Adriane Belló-Klein, Claiton I. Schwertz, David Driemeier, Adriana Raffin Pohlmann & Sílvia Stanisçuaski Guterres. (2021) Oral delivery of ambrisentan-loaded lipid-core nanocapsules as a novel approach for the treatment of pulmonary arterial hypertension. International Journal of Pharmaceutics 610, pages 121181.
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Kalyani Sakure, Leena Kumari & Hemant Badwaik. (2020) Development and evaluation of solid dispersion based rapid disintegrating tablets of poorly water-soluble anti-diabetic drug. Journal of Drug Delivery Science and Technology 60, pages 101942.
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Jamshed Haneef, Datta Markad & Renu Chadha. (2020) Interaction Map Driven Cocrystallization of Ambrisentan: Structural and Biopharmaceutical Evaluation. Crystal Growth & Design 20:7, pages 4612-4620.
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Avinash Ramrao Tekade & Jyoti Narayan Yadav. (2020) A Review on Solid Dispersion and Carriers Used Therein for Solubility Enhancement of Poorly Water Soluble Drugs. Advanced Pharmaceutical Bulletin 10:3, pages 359-369.
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Xiaojing Xia, Zeng Tan, Yaru Fan, Ying Hu & Jin Deng. (2020) Preparation and evaluation of a novel solid dispersion using leucine as carrier. Journal of Pharmacy and Pharmacology 72:2, pages 175-184.
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