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Drug Development and Industrial Pharmacy Volume 45, 2019 - Issue 8
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Research Article

Solubility measurement, Hansen solubility parameters and solution thermodynamics of gemfibrozil in different pharmaceutically used solvents

Mohd Abul KalamNanobiotechnology Unit, Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia;
,
Sultan AlshehriDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia;
,
Aws AlshamsanNanobiotechnology Unit, Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia;
,
Musaed AlkholiefNanobiotechnology Unit, Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia;
,
Raisuddin AliDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia; ;Central Laboratory, Research Center, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia
&
Faiyaz ShakeelDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia; Correspondence[email protected]
Pages 1258-1264 | Received 24 Dec 2018, Accepted 08 Mar 2019, Published online: 14 May 2019

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Ramadan Al-Shdefat, Mohammad Hailat & Osama Y. Alshogran. (2022) Solubilization of a novel antitumor drug ribociclib in water and ten different organic solvents at different temperatures. Drug Development and Industrial Pharmacy 48:1, pages 12-20.
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Sachin K. Jagdale & Rajesh B. Nawale. (2021) Experimental measurement – correlation of solubility and dissolution thermodynamics study of itraconazole in pure monosolvents at various temperatures. Drug Development and Industrial Pharmacy 47:7, pages 1038-1051.
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Faiyaz Shakeel, Md. Khalid Anwer, Abdullah M.E Youssof, Nazrul Haq, Fars K. Alanazi & Ibrahim A. Alsarra. (2021) Solubilization, Hansen solubility parameters, and thermodynamic studies of delafloxacin in (transcutol + 1-butyl-3-methyl imidazolium hexafluorophosphate) mixtures. Drug Development and Industrial Pharmacy 47:4, pages 654-662.
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Ramadan Al-Shdefat. (2020) Solubility determination and solution thermodynamics of olmesartan medoxomil in (PEG-400 + water) cosolvent mixtures. Drug Development and Industrial Pharmacy 46:12, pages 2098-2104.
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Xue-Xian Lang, Hong-Yao Li, Hao-Wen Cao, Yan-Song Chen, Peng-Xiang Zhang, Hai-Jiao Wang & Ming-Qi Wang. (2022) Exploring the binding mechanism of amine-functionalized tetraaryl imidazole fluorescent ligands with lipase: Insights from multi-spectroscopic, thermodynamic and docking approaches. Dyes and Pigments 205, pages 110535.
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Mingdi Liu, Zeren Shang, Yumin Liu, Guangle Wang, Ping Song, Haichao Li, Maolin Li & Dandan Han. (2021) Measurement and correlation of the solubility of 3-methoxybenzoic acid in fourteen mono-solvents at temperatures from 278.15 K to 323.15 K. The Journal of Chemical Thermodynamics 161, pages 106511.
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Mohammed H. Alqarni, Nazrul Haq, Prawez Alam, Maged S. Abdel-Kader, Ahmed I. Foudah & Faiyaz Shakeel. (2021) Solubility data, Hansen solubility parameters and thermodynamic behavior of pterostilbene in some pure solvents and different (PEG-400 + water) cosolvent compositions. Journal of Molecular Liquids 331, pages 115700.
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Faiyaz Shakeel, Nazrul Haq & Ibrahim A. Alsarra. (2021) Equilibrium solubility determination, Hansen solubility parameters and solution thermodynamics of cabozantinib malate in different monosolvents of pharmaceutical importance. Journal of Molecular Liquids 324, pages 115146.
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Faiyaz Shakeel, Nazrul Haq, Ibrahim Alsarra & Sultan Alshehri. (2021) Solubility Data, Solubility Parameters and Thermodynamic Behavior of an Antiviral Drug Emtricitabine in Different Pure Solvents: Molecular Understanding of Solubility and Dissolution. Molecules 26:3, pages 746.
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Guangle Wang, Gang Wang, Junbo Gong, Wenlong Li, Zeren Shang, Shaolei Zhao, Weibing Dong & Yan Wang. (2020) Experimental determination and computational analysis of solid–liquid phase equilibrium of nifedipine in twelve pure solvents. The Journal of Chemical Thermodynamics 150, pages 106223.
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Faiyaz Shakeel, Nazrul Haq, Fars K. Alanazi, Saleh A. Alanazi & Ibrahim A. Alsarra. (2020) Solubility of sinapic acid in various (Carbitol + water) systems: computational modeling and solution thermodynamics. Journal of Thermal Analysis and Calorimetry 142:4, pages 1437-1446.
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Sultan Alshehri & Faiyaz Shakeel. (2020) Solubility determination, various solubility parameters and solution thermodynamics of sunitinib malate in some cosolvents, water and various (Transcutol + water) mixtures. Journal of Molecular Liquids 307, pages 112970.
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Abdullah Alanazi, Sultan Alshehri, Mohammad Altamimi & Faiyaz Shakeel. (2020) Solubility determination and three dimensional Hansen solubility parameters of gefitinib in different organic solvents: Experimental and computational approaches. Journal of Molecular Liquids 299, pages 112211.
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Mohd Abul Kalam, Aws Alshamsan, Musaed Alkholief, Ibrahim A. Alsarra, Raisuddin Ali, Nazrul Haq, Md Khalid Anwer & Faiyaz Shakeel. (2020) Solubility Measurement and Various Solubility Parameters of Glipizide in Different Neat Solvents. ACS Omega 5:3, pages 1708-1716.
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