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Drug Development and Industrial Pharmacy Volume 45, 2019 - Issue 9
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Research Articles

Nano- and microcrystals of griseofulvin subcutaneously administered to rats resulted in improved bioavailability and sustained release

Kalle SigfridssonAdvanced Drug Delivery, Pharmaceutical Science, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden; Correspondence[email protected]
,
Hanna RydbergAdvanced Drug Delivery, Pharmaceutical Science, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden;
&
Marie StrimforsBioscience, CVRM, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden
Pages 1477-1486 | Received 03 Apr 2019, Accepted 20 May 2019, Published online: 01 Jul 2019

Citations (8)

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Divya Sharma, Faraj Atassi, Steve Cook, Stacey Marden, Jianyan Wang, Aixiang Xue, David J. Wagner, Guangnong Zhang & Wenzhan Yang. (2021) Experimental design, development and evaluation of extended release subcutaneous thermo-responsive in situ gels for small molecules in drug discovery. Pharmaceutical Development and Technology 26:10, pages 1079-1089.
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Tao Liu, Xinxin Yu, Haipeng Yin & Jan P. Möschwitzer. (2019) Advanced modification of drug nanocrystals by using novel fabrication and downstream approaches for tailor-made drug delivery. Drug Delivery 26:1, pages 1092-1103.
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Articles from other publishers (6)

Krishna C. Aluri, Kalle Sigfridsson, Aixiang Xue, Niresh Hariparsad, Dermot McGinnity & Diane Ramsden. (2023) Pharmacokinetic evaluation of poorly soluble compounds formulated as nano- or microcrystals after intraperitoneal injection to mice. International Journal of Pharmaceutics 636, pages 122787.
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Hao Lou & Michael J. Hageman. (2023) Development of Drug Release Model for Suspensions in ESCAR (Emulator of SubCutaneous Absorption and Release). The AAPS Journal 25:3.
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Eman Gomaa, Mohamed S. Attia, Fakhr-Eldin S. Ghazy, Abdalla E.A. Hassan & Azza A. Hasan. (2022) Pump-free electrospraying: A novel approach for fabricating Soluplus®-based solid dispersion nanoparticles. Journal of Drug Delivery Science and Technology 67, pages 103027.
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Elene De Cleyn, René Holm, Tatsiana Khamiakova & Guy Van den Mooter. (2021) Picking up good vibrations: Exploration of the intensified vibratory mill via a modern design of experiments. International Journal of Pharmaceutics 598, pages 120367.
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Andrea Sekulović, Marion Petit, Ruud Verrijk, Thomas Rades & Jukka Rantanen. (2021) Probabilistic modeling of an injectable aqueous crystalline suspension using influence networks. International Journal of Pharmaceutics 596, pages 120283.
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Kalle Sigfridsson, Torbjörn Arvidsson, Aixiang Xue, David J. Wagner, Petar Pop-Damkov, Guangnong Zhang & Marie Strimfors. (2020) A candidate drug administered subcutaneously to rodents as drug particles showing hepatic recirculation which influenced the sustained release process. International Journal of Pharmaceutics 581, pages 119252.
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