411
Views
24
CrossRef citations to date
0
Altmetric
Research Articles

Systematic implementation of quality-by-design (QbD) to develop NSAID-loaded nanostructured lipid carriers for ocular application: preformulation screening studies and statistical hybrid-design for optimization of variables

, &
Pages 443-455 | Received 30 Sep 2019, Accepted 22 Jan 2020, Published online: 09 Feb 2020

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Sangseo Kim, Sadikalmahdi Abdella, Fatima Abid, Franklin Afinjuomo, Souha H Youssef, Amy Holmes, Yunmei Song, Sachin Vaidya & Sanjay Garg. (2023) Development and Optimization of Imiquimod-Loaded Nanostructured Lipid Carriers Using a Hybrid Design of Experiments Approach. International Journal of Nanomedicine 18, pages 1007-1029.
Read now
Shilpa Mandpe, Eknath Kole, Vishal Parate, Aniruddha Chatterjee, Arun Mujumdar & Jitendra Naik. (2023) Design, development, and evaluation of spray dried flurbiprofen loaded sustained release polymeric nanoparticles using QBD approach to manage inflammation. Drying Technology 41:15, pages 2418-2430.
Read now
Ali Sartaj, Annu  , Meraj Alam, Largee Biswas, Mohammad Shahar Yar, Showkat Rasool Mir, Anita Kamra Verma, Sanjula Baboota & Javed Ali. (2022) Combinatorial delivery of Ribociclib and green tea extract mediated nanostructured lipid carrier for oral delivery for the treatment of breast cancer synchronising in silico, in vitro, and in vivo studies. Journal of Drug Targeting 30:10, pages 1113-1134.
Read now

Articles from other publishers (21)

Amitkumar Virani, Nirali Dholaria, Namrata Matharoo & Bozena Michniak-Kohn. (2023) A Study of Microemulsion Systems for Transdermal Delivery of Risperidone Using Penetration Enhancers. Journal of Pharmaceutical Sciences 112:12, pages 3109-3119.
Crossref
Li Kar Stella Tan, Chee Wun How, Liang Ee Low, Boon Hoong Ong, Jian Sheng Loh, Su-Yin Lim, Yong Sze Ong & Jhi Biau Foo. (2023) Magnetic-guided targeted delivery of zerumbone/SPION co-loaded in nanostructured lipid carrier into breast cancer cells. Journal of Drug Delivery Science and Technology 87, pages 104830.
Crossref
Vishal Rathod, Bhavin Gajera, Anusha Pinninti, Irfan A. Mohammed & Rutesh H. Dave. (2023) Strategizing Spray Drying Process Optimization for the Manufacture of Redispersible Indomethacin Nanoparticles Using Quality-by-Design Principles. AAPS PharmSciTech 24:5.
Crossref
Burcu Uner, Samet Ozdemir, Cetin Tas, Melike Uner & Yildiz Ozsoy. (2023) Loteprednol-Loaded Nanoformulations for Corneal Delivery by Quality-by-Design Concepts: Optimization, Characterization, and Anti-inflammatory Activity. AAPS PharmSciTech 24:4.
Crossref
Harsh Shah, Kushal Shah, Bhavin Gajera, Rutesh H. Dave & David R. Taft. (2023) Developing a Formulation Strategy Coupled with PBPK Modeling and Simulation for the Weakly Basic Drug Albendazole. Pharmaceutics 15:4, pages 1040.
Crossref
Akanksha Patel & Abhay Dharamsi. (2023) Voriconazole Loaded Lipidic Nanoparticles for Ophthalmic Delivery: Development Using QbD Combined with Risk-based Approach. Current Nanomedicine 13:1, pages 56-69.
Crossref
Amal H. El-Kamel & Asmaa A. Ashour. 2023. Advanced Drug Delivery Systems. Advanced Drug Delivery Systems.
Felipe M. González-Fernández, Andrea Delledonne, Sara Nicoli, Paolo Gasco, Cristina Padula, Patrizia Santi, Cristina Sissa & Silvia Pescina. (2023) Nanostructured Lipid Carriers for Enhanced Transscleral Delivery of Dexamethasone Acetate: Development, Ex Vivo Characterization and Multiphoton Microscopy Studies. Pharmaceutics 15:2, pages 407.
Crossref
Vivek D. Patel, Vishal Rathod, Rahul V. Haware & William C. Stagner. (2023) Optimized L-SNEDDS and spray-dried S-SNEDDS using a linked QbD-DM3 rational design for model compound ketoprofen. International Journal of Pharmaceutics 631, pages 122494.
Crossref
Tausif Alam. (2022) Quality by design based development of nanostructured lipid carrier: a risk based approach. Exploration of Medicine, pages 617-638.
Crossref
Hery Mitsutake, Gustavo H. Rodrigues da Silva, Márcia C. Breitkreitz, Eneida de Paula & Heloisa N. Bordallo. (2022) Neither too little nor too much: Finding the ideal proportion of excipients using confocal Raman and chemometrics. European Journal of Pharmaceutics and Biopharmaceutics 181, pages 136-146.
Crossref
Biswarup Das, Amit Kumar Nayak & Subrata Mallick. (2022) Lipid-based nanocarriers for ocular drug delivery: An updated review. Journal of Drug Delivery Science and Technology 76, pages 103780.
Crossref
Harsh G. Shah, Vishal Rathod, Pratap Basim, Bhavin Gajera & Rutesh H. Dave. (2022) Understanding the Impact of Multi-factorial Composition on Efficient Loading of the Stable Ketoprofen Nanoparticles on Orodispersible Films Using Box-Behnken Design. Journal of Pharmaceutical Sciences 111:5, pages 1451-1462.
Crossref
Amit Kumar Nayak, Md Saquib Hasnain, Anindita Behera, Amal Kumar Dhara & Dilipkumar Pal. 2022. Biological Macromolecules. Biological Macromolecules 339 379 .
Lorena Bonilla, Marta Espina, Patricia Severino, Amanda Cano, Miren Ettcheto, Antoni Camins, Maria Luisa García, Eliana B. Souto & Elena Sánchez-López. (2021) Lipid Nanoparticles for the Posterior Eye Segment. Pharmaceutics 14:1, pages 90.
Crossref
Felipe M. González-Fernández, Annalisa Bianchera, Paolo Gasco, Sara Nicoli & Silvia Pescina. (2021) Lipid-Based Nanocarriers for Ophthalmic Administration: Towards Experimental Design Implementation. Pharmaceutics 13:4, pages 447.
Crossref
Ionuț-Mihai Tănase, Laura Sbârcea, Adriana Ledeţi, Paul Barvinschi, Denisa Cîrcioban, Gabriela Vlase, Renata-Maria Văruţ & Ionuţ Ledeţi. (2020) Compatibility studies with pharmaceutical excipients for aripiprazole–heptakis (2,6-di-O-methyl)-β-cyclodextrin supramolecular adduct. Journal of Thermal Analysis and Calorimetry 142:5, pages 1963-1976.
Crossref
Gustavo Braga, Katieli da Silva Souza Campanholi, Sabrina Barbosa de Souza Ferreira, Italo Rodrigo Calori, Jean Halison de Oliveira, Douglas Vanzin, Marcos Luciano Bruschi, Rodrigo Meneghetti Pontes, Paulo Henrique Março, André Luiz Tessaro, Noboru Hioka & Wilker Caetano. (2020) Tautomeric and Aggregational Dynamics of Curcumin-Supersaturated Pluronic Nanocarriers. ACS Applied Polymer Materials 2:11, pages 4493-4511.
Crossref
Vishal Rathod, William C. Stagner, Bhavin Gajera & Rahul V. Haware. (2020) Hybridized nanoamorphous micellar dispersion using a QbD–DM3 linked rational product design strategy for ritonavir: A BCS IV drug. International Journal of Pharmaceutics 588, pages 119727.
Crossref
Srividya Gorantla, Vamshi Krishna Rapalli, Tejashree Waghule, Prem Prakash Singh, Sunil Kumar Dubey, Ranendra N. SahaGautam Singhvi. (2020) Nanocarriers for ocular drug delivery: current status and translational opportunity. RSC Advances 10:46, pages 27835-27855.
Crossref
Bavani Subramaniam, Zahid H. Siddik & Noor Hasima Nagoor. (2020) Optimization of nanostructured lipid carriers: understanding the types, designs, and parameters in the process of formulations. Journal of Nanoparticle Research 22:6.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.