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Journal of the American College of Nutrition Volume 32, 2013 - Issue 3
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ORIGINAL RESEARCH

Chronic Intake of Onion Extract Containing Quercetin Improved Postprandial Endothelial Dysfunction in Healthy Men

Hideki Nakayama MSc House Foods Corporation, Yotsukaido, Chiba, JAPAN
,
Nobuaki Tsuge PhD House Foods Corporation, Yotsukaido, Chiba, JAPAN
,
Hiroshi Sawada PhD House Foods Corporation, Yotsukaido, Chiba, JAPAN
&
Yukihito Higashi MD, PhD, FAHA Department of Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, JAPAN
Pages 160-164 | Received 05 Jul 2012, Accepted 12 Apr 2013, Published online: 25 Jul 2013

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Burçin Karavelioğlu & Mustafa Hoca. (2022) Potential effects of onion (Allium cepa L.) and its phytomolecules on non-communicable chronic diseases: a review. The Journal of Horticultural Science and Biotechnology 97:1, pages 24-33.
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Articles from other publishers (25)

Junji Terao. (2023) Potential Role of Quercetin Glycosides as Anti-Atherosclerotic Food-Derived Factors for Human Health. Antioxidants 12:2, pages 258.
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Konstantina Papastavropoulou & Charalampos Proestos. 2023. Functional Foods and Their Implications for Health Promotion. Functional Foods and Their Implications for Health Promotion 3 28 .
Claudia Balderas, Javier Angulo, Alejandro Sevilleja-Ortiz, Concepción Peiró, Susana Vallejo, Pilar Dongil, Begoña de Ancos & Concepción Sánchez-Moreno. (2022) Onion and Apple Functional Ingredients Intake Improves Antioxidant and Inflammatory Status and Vascular Injury in Obese Zucker Rats. Antioxidants 11:10, pages 1953.
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Jack N. Losso. (2022) The Potential of Dietary Bioactive Compounds against SARS-CoV-2 and COVID-19-Induced Endothelial Dysfunction. Molecules 27:5, pages 1623.
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Esther García-Díez, Marta Cuesta-Hervás, Ana M. Veses-Alcobendas, Óscar Alonso-Gordo, Elena García-Maldonado, Miriam Martínez-Suárez, Beatriz Herranz, M. Pilar Vaquero, María Dolores Álvarez & Jara Pérez-Jiménez. (2021) Acute supplementation with grapes in obese subjects did not affect postprandial metabolism: a randomized, double-blind, crossover clinical trial. European Journal of Nutrition 60:5, pages 2671-2681.
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Phakorn Papan, Jiraporn Kantapan, Padchanee Sangthong, Puttinan Meepowpan & Nathupakorn Dechsupa. (2020) Iron (III)-Quercetin Complex: Synthesis, Physicochemical Characterization, and MRI Cell Tracking toward Potential Applications in Regenerative Medicine. Contrast Media & Molecular Imaging 2020, pages 1-22.
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Damini Kothari, Woo-Do Lee & Soo-Ki Kim. (2020) Allium Flavonols: Health Benefits, Molecular Targets, and Bioavailability. Antioxidants 9:9, pages 888.
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Bahare Salehi, Laura Machin, Lianet Monzote, Javad Sharifi-Rad, Shahira M. Ezzat, Mohamed A. Salem, Rana M. Merghany, Nihal M. El Mahdy, Ceyda Sibel Kılıç, Oksana Sytar, Mehdi Sharifi-Rad, Farukh Sharopov, Natália Martins, Miquel Martorell & William C. Cho. (2020) Therapeutic Potential of Quercetin: New Insights and Perspectives for Human Health. ACS Omega 5:20, pages 11849-11872.
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Nicola P. Bondonno, Catherine P. Bondonno, Natalie C. Ward, Richard J. Woodman, Jonathan M. Hodgson & Kevin D. Croft. (2019) Enzymatically modified isoquercitrin improves endothelial function in volunteers at risk of cardiovascular disease. British Journal of Nutrition 123:2, pages 182-189.
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Di Zhang, Mingzhao Du, Ying Wei, Chengtao Wang & Lingqin Shen. (2018) A review on the structure-activity relationship of dietary flavonoids for protecting vascular endothelial function: Current understanding and future issues. Journal of Food Biochemistry 42:5, pages e12557.
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Rahul V. Patel, Bhupendra M. Mistry, Surendra K. Shinde, Riyaz Syed, Vijay Singh & Han-Seung Shin. (2018) Therapeutic potential of quercetin as a cardiovascular agent. European Journal of Medicinal Chemistry 155, pages 889-904.
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Nicola P. Bondonno, Catherine P. Bondonno, Lauren C. Blekkenhorst, Michael J. Considine, Ghassan Maghzal, Roland Stocker, Richard J. Woodman, Natalie C. Ward, Jonathan M. Hodgson & Kevin D. Croft. (2018) Flavonoid-Rich Apple Improves Endothelial Function in Individuals at Risk for Cardiovascular Disease: A Randomized Controlled Clinical Trial. Molecular Nutrition & Food Research 62:3, pages 1700674.
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Junji Terao. (2017) Factors modulating bioavailability of quercetin-related flavonoids and the consequences of their vascular function. Biochemical Pharmacology 139, pages 15-23.
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Guo-Yi Tang, Xiao Meng, Ya Li, Cai-Ning Zhao, Qing Liu & Hua-Bin Li. (2017) Effects of Vegetables on Cardiovascular Diseases and Related Mechanisms. Nutrients 9:8, pages 857.
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BERNARDITA MONSALVE, ANIBAL CONCHA-MEYER, IVÁN PALOMO & EDUARDO FUENTES. (2017) Mechanisms of Endothelial Protection by Natural Bioactive Compounds from Fruit and Vegetables. Anais da Academia Brasileira de Ciências 89:1 suppl, pages 615-633.
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Catarina Rendeiro, Honglin Dong, Caroline Saunders, Laura Harkness, Melvin Blaze, Yanpeng Hou, Ronald L. Belanger, Giulia Corona, Julie A. Lovegrove & Jeremy P. E. Spencer. (2017) Flavanone-rich citrus beverages counteract the transient decline in postprandial endothelial function in humans: a randomised, controlled, double-masked, cross-over intervention study. British Journal of Nutrition 116:12, pages 1999-2010.
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Bouke N Salden, Freddy J Troost, Eric de Groot, Yala R Stevens, Marta Garcés-Rimón, Sam Possemiers, Bjorn Winkens & Ad A Masclee. (2016) Randomized clinical trial on the efficacy of hesperidin 2S on validated cardiovascular biomarkers in healthy overweight individuals. The American Journal of Clinical Nutrition 104:6, pages 1523-1533.
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Nicola P Bondonno, Catherine P Bondonno, Lisa Rich, Emilie Mas, Sujata Shinde, Natalie C Ward, Jonathan M Hodgson & Kevin D Croft. (2016) Acute effects of quercetin-3-O-glucoside on endothelial function and blood pressure: a randomized dose-response study. The American Journal of Clinical Nutrition 104:1, pages 97-103.
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Nicola P. Bondonno, Catherine P. Bondonno, Jonathan M. Hodgson, Natalie C. Ward & Kevin D. Croft. (2015) The Efficacy of Quercetin in Cardiovascular Health. Current Nutrition Reports 4:4, pages 290-303.
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Yasuaki Kashino, Kaeko Murota, Namiko Matsuda, Muneaki Tomotake, Takuya Hamano, Rie Mukai & Junji Terao. (2015) Effect of Processed Onions on the Plasma Concentration of Quercetin in Rats and Humans. Journal of Food Science 80:11, pages H2597-H2602.
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Jordan LoaderDavid MonteroChristian LorenzenRani WattsCindy MéziatCyril ReboulSimon StewartGuillaume Walther. (2015) Acute Hyperglycemia Impairs Vascular Function in Healthy and Cardiometabolic Diseased Subjects. Arteriosclerosis, Thrombosis, and Vascular Biology 35:9, pages 2060-2072.
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Eun-Yong Choi, Hansongyi Lee, Jong Shin Woo, Hyun Hee Jang, Seung Joon Hwang, Hyun Soo Kim, Woo-Sik Kim, Young-Seol Kim, Ryowon Choue, Yong-Jun Cha, Jung-Eun Yim & Weon Kim. (2015) Effect of onion peel extract on endothelial function and endothelial progenitor cells in overweight and obese individuals. Nutrition 31:9, pages 1131-1135.
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Clara Colina-Coca, Luis M. Rodríguez-Alcalá, Javier Fontecha, Diana González-Peña, Begoña de Ancos & Concepción Sánchez-Moreno. (2014) Effects of hypercholesterolemic diet enriched with onion as functional ingredient on fatty acid metabolism in Wistar rats. Food Research International 64, pages 546-552.
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Ana Rodriguez-Mateos, David Vauzour, Christian G. Krueger, Dhanansayan Shanmuganayagam, Jess Reed, Luca Calani, Pedro Mena, Daniele Del Rio & Alan Crozier. (2014) Bioavailability, bioactivity and impact on health of dietary flavonoids and related compounds: an update. Archives of Toxicology 88:10, pages 1803-1853.
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Sigrid Theunissen, Julie Schumacker, François Guerrero, Frauke Tillmans, Antoine Boutros, Kate Lambrechts, Aleksandra Mazur, Massimo Pieri, Peter Germonpré & Costantino Balestra. (2013) Dark chocolate reduces endothelial dysfunction after successive breath-hold dives in cool water. European Journal of Applied Physiology 113:12, pages 2967-2975.
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