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Original Articles

Carbohydrate‐Based Molecular Scaffolding

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Pages 97-138 | Received 07 Oct 2005, Accepted 18 Nov 2005, Published online: 17 Aug 2006

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Laura Cipolla, Ana C Araújo, Davide Bini, Luca Gabrielli, Laura Russo & Nasrin Shaikh. (2010) Discovery and design of carbohydrate-based therapeutics. Expert Opinion on Drug Discovery 5:8, pages 721-737.
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Jie Wang, Yukun Zhang, Qi Lu, Dongming Xing & Renshuai Zhang. (2021) Exploring Carbohydrates for Therapeutics: A Review on Future Directions. Frontiers in Pharmacology 12.
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Hongfei Jiang, Xiaofei Qin, Qi Wang, Qi Xu, Jie Wang, Yudong Wu, Wujun Chen, Chao Wang, Tingting Zhang, Dongming Xing & Renshuai Zhang. (2021) Application of carbohydrates in approved small molecule drugs: A review. European Journal of Medicinal Chemistry 223, pages 113633.
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Yadavali Siva Prasad, S. Manikandan, Krishnamoorthy Lalitha, Miryala Sandeep, R. Vara Prasad, R. Arun Kumar, C.S. Srinandan, C. Uma Maheswari, Vellaisamy Sridharan & Subbiah Nagarajan. (2020) Supramolecular gels of gluconamides derived from renewable resources: Antibacterial and anti‐biofilm applications. Nano Select 1:5, pages 510-524.
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Mana Mohan Mukherjee, Sajal Kumar Maity & Rina Ghosh. (2020) One-pot construction of carbohydrate scaffolds mediated by metal catalysts. RSC Advances 10:54, pages 32450-32475.
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R. Prasanna, S. Purushothaman & R. Raghunathan. (2020) 1,3-Dipolar cycloaddition reaction on carbohydrate template: Stereoselective synthesis of glycospiroheterocycles. Tetrahedron 76:35, pages 131398.
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Nidhi Mishra, Vinod K. Tiwari & Richard R. Schmidt. 2020. Carbohydrates in Drug Discovery and Development. Carbohydrates in Drug Discovery and Development 1 69 .
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Virendra Prasad, Nidhi Mishra, Anand K. Agrahari, Sumit K. Singh, Prabhu P. Mohapatra & Vinod K. Tiwari. (2019) Cycloelimination-assisted Combinatorial Synthesis of Diverse Heterocyclic Scaffolds of Chemotherapeutic Values. Current Organic Chemistry 23:7, pages 768-808.
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Henok H. Kinfe. (2019) Versatility of glycals in synthetic organic chemistry: coupling reactions, diversity oriented synthesis and natural product synthesis. Organic & Biomolecular Chemistry 17:17, pages 4153-4182.
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Guang-Zong Tian, Jing Hu, Heng-Xi Zhang, Christoph Rademacher, Xiao-Peng Zou, Hong-Ning Zheng, Fei Xu, Xiao-Li Wang, Torsten Linker & Jian Yin. (2018) Synthesis and conformational analysis of linear homo- and heterooligomers from novel 2-C-branched sugar amino acids (SAAs). Scientific Reports 8:1.
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Noha A. Saleh & Wael M. Elshemey. (2017) Structure-based drug design of novel peptidomimetic cellulose derivatives as HCV-NS3 protease inhibitors. Life Sciences 187, pages 58-63.
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Mylène Richard, Yves Chapleur & Nadia Pellegrini-Moïse. (2016) Spiro sugar-isoxazolidine scaffold as useful polyfunctional building block for peptidomimetics design. Carbohydrate Research 422, pages 24-33.
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Stephen Barron & Paul V. Murphy. (2014) Synthesis of iminosugar derivatives presenting naphthyl and alkyl amine interacting groups and binding to somatostatin receptors. MedChemComm 5:8, pages 1150-1158.
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Shino Manabe, Masanori Yamaguchi & Yukishige Ito. (2013) Sulfonylcarbamate as a versatile and unique hydroxy-protecting group: a protecting group stable under severe conditions and labile under mild conditions. Chemical Communications 49:75, pages 8332.
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Annemiek D. Knijnenburg, Emile Spalburg, Albert J. de Neeling, Roos H. Mars‐Groenendijk, Daan Noort, Gijsbert M. Grotenbreg, Gijs A. van der Marel, Herman S. Overkleeft & Mark Overhand. (2012) Ring‐Extended Gramicidin S Analogs Containing cis δ ‐Sugar Amino Acid Turn Mimetics with Varying Ring Size . Helvetica Chimica Acta 95:12, pages 2544-2561.
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Bhuwan B. Mishra, Dhananjay Kumar, Amrita Mishra, Prabhu P. Mohapatra & Vinod K. Tiwari. 2012. Advances in Heterocyclic Chemistry Volume 107. Advances in Heterocyclic Chemistry Volume 107 41 99 .
Jian Zhou, Marie-Christine Matos & Paul V. Murphy. (2011) Synthesis of a Benzomacrolactone-Based Somatostatin Mimetic. Organic Letters 13:21, pages 5716-5719.
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Seerat Fatima, Vivek Parashar Pandey, Surendra Singh Bisht & Rama P. Tripathi. (2011) Application of butenonyl-C-glucosides in the synthesis of pyrazolinyl-, aminopyrimidinyl- and biphenyl methyl-β-d-C-glucopyranosides. Molecular Diversity 15:3, pages 759-768.
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Annemiek D. Knijnenburg, Adriaan W. Tuin, Emile Spalburg, Albert J. de Neeling, Roos H. Mars‐Groenendijk, Daan Noort, José M. Otero, Antonio L. Llamas‐Saiz, Mark J. van Raaij, Gijs A. van der Marel, Herman S. Overkleeft & Mark Overhand. (2011) Exploring the Conformational and Biological Versatility of β‐Turn‐Modified Gramicidin S by Using Sugar Amino Acid Homologues that Vary in Ring Size. Chemistry – A European Journal 17:14, pages 3995-4004.
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Yunxue Zhao, Min Liu, Vincent Chagnault, Juying Wang, Xiumei Zhang & Paul V. Murphy. (2011) Biological study of a somatostatin mimetic based on the 1-deoxynojrimycin scaffold. Bioorganic & Medicinal Chemistry Letters 21:2, pages 824-828.
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Dilip V. Jarikote, Wei Li, Tao Jiang, Leif A. Eriksson & Paul V. Murphy. (2011) Towards echinomycin mimetics by grafting quinoxaline residues on glycophane scaffolds. Bioorganic & Medicinal Chemistry 19:2, pages 826-835.
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Ana M. Gómez, Ana Pedregosa, Clara Uriel, Serafín Valverde & J. Cristóbal López. (2010) 1-exo-Alkylidene-2,3-anhydrofuranoses: Valuable Synthons in the Preparation of Furanose-Based Templates. European Journal of Organic Chemistry 2010:29, pages 5619-5632.
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Dilip Venkatrao Jarikote & Paul V. Murphy. (2010) Metathesis and Macrocycles with Embedded Carbohydrates. European Journal of Organic Chemistry 2010:26, pages 4959-4970.
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Ming Zhong, Xiang-Bao Meng & Zhong-Jun Li. (2010) Synthesis of γ-aminobutyric acid analogs based on carbohydrate scaffolds. Carbohydrate Research 345:9, pages 1099-1106.
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Alexandre Novoa, Nadia Pellegrini-Moïse, Denise Bechet, Muriel Barberi-Heyob & Yves Chapleur. (2010) Sugar-based peptidomimetics as potential inhibitors of the vascular endothelium growth factor binding to neuropilin-1. Bioorganic & Medicinal Chemistry 18:9, pages 3285-3298.
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Laura CipollaBarbara La FerlaCristina AiroldiCristiano ZonaAlexandre OrsatoNasrin ShaikhLaura RussoFrancesco Nicotra. (2010) Carbohydrate mimetics and scaffolds: sweet spots in medicinal chemistry. Future Medicinal Chemistry 2:4, pages 587-599.
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Kirpal S. Bisht & Talal F. Al-Azemi. 2010. Green Polymer Chemistry: Biocatalysis and Biomaterials. Green Polymer Chemistry: Biocatalysis and Biomaterials 175 199 .
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Ruizhi Wu, Talal F. AL-Azemi & Kirpal S. Bisht. (2009) One-Shot Block Copolymerization of a Functional Seven-Membered Cyclic Carbonate Derived from l -Tartaric Acid with ε-Caprolactone . Macromolecules 42:7, pages 2401-2410.
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J. S. Shane Rountree & Paul V. Murphy. (2009) Synthesis of a Novel Polyhydroxylated Salicylic Acid Lactone Framework. Organic Letters 11:4, pages 871-874.
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Issa Samb, Nadia Pellegrini-Moïse, Sandrine Lamandé-Langle & Yves Chapleur. (2009) Efficient functionalizations of a pyranosido-pyrimidine scaffold. Tetrahedron 65:4, pages 896-902.
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Ruizhi Wu, Talal F. Al-Azemi & Kirpal S. Bisht. (2008) Functionalized Polycarbonate Derived from Tartaric Acid: Enzymatic Ring-Opening Polymerization of a Seven-Membered Cyclic Carbonate. Biomacromolecules 9:10, pages 2921-2928.
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Francesco Nicotra, Laura Cipolla, Francesco Peri & Barbara La Ferla. (2008) Carbohydrate scaffolds in chemical genomic studies. Journal of Biotechnology 136, pages S16-S17.
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Dearbhla Doyle & Paul V. Murphy. (2008) Synthesis of novel glycophanes derived from glucuronic acid by ring closing alkene and alkyne metathesis. Carbohydrate Research 343:15, pages 2535-2544.
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Vincent Chagnault, Jérôme Lalot & Paul V. Murphy. (2008) Synthesis of Somatostatin Mimetics Based on 1‐Deoxynojirimycin. ChemMedChem 3:7, pages 1071-1076.
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Paul V. Murphy. (2007) Peptidomimetics, Glycomimetics and Scaffolds from Carbohydrate Building Blocks. European Journal of Organic Chemistry 2007:25, pages 4177-4187.
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Ingrid Velter, Barbara La Ferla & Francesco Nicotra. (2006) Carbohydrate‐Based Molecular Scaffolding. ChemInform 37:47.
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